Klk15 (kallikrein related peptidase 15)

Gene: Klk15 (kallikrein related peptidase 15) Ictidomys tridecemlineatus

Analyze

Symbol:

Klk15

Name:

kallikrein related peptidase 15

RGD ID:

12718292

Description:

ENCODES a protein that exhibits serine-type endopeptidase activity (inferred); serine-type peptidase activity (inferred); INVOLVED IN proteolysis (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN secretory granule (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

kallikrein-15

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	22,663,277 - 22,665,277 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936889	539,403 - 544,136 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936889	539,195 - 544,136 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

proteolysis (IEA)

Cellular Component

secretory granule (IEA)

Molecular Function

protein binding (ISO)

serine-type endopeptidase activity (IEA)

serine-type peptidase activity (IEA)

References

Additional References at PubMed

PMID:22301074

Genomics

Comparative Map Data

Klk15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	22,663,277 - 22,665,277 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936889	539,403 - 544,136 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936889	539,195 - 544,136 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KLK15
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	50,825,289 - 50,833,574 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	50,825,289 - 50,837,213 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	51,328,545 - 51,336,830 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	56,020,357 - 56,026,591 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	19	48,379,647 - 48,385,881 (-)	NCBI		Celera
Cytogenetic Map	19	q13.33	NCBI
HuRef	19	47,663,585 - 47,669,818 (-)	NCBI		HuRef
CHM1_1	19	51,330,337 - 51,336,572 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	53,914,924 - 53,923,210 (-)	NCBI		T2T-CHM13v2.0

Klk15
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	43,578,829 - 43,589,459 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	43,583,164 - 43,589,063 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	43,929,405 - 43,940,035 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	43,933,740 - 43,939,639 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	51,189,141 - 51,194,960 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	43,801,813 - 43,807,632 (+)	NCBI		MGSCv36	mm8
Celera	7	39,392,357 - 39,398,200 (+)	NCBI		Celera
Cytogenetic Map	7	B3	NCBI
cM Map	7	28.41	NCBI

Klk15
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	103,834,215 - 103,843,321 (+)	NCBI		GRCr8
mRatBN7.2	1	94,699,422 - 94,706,626 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	94,499,413 - 94,502,789 (-)	Ensembl		mRatBN7.2 Ensembl
mRatBN7.2 Ensembl	1	94,703,158 - 94,706,329 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	1	100,187,830 - 100,196,494 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	99,398,248 - 99,401,126 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	1	100,189,515 - 100,196,281 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	100,465,312 - 100,473,383 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	94,683,175 - 94,690,080 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	88,964,867 - 88,973,693 (+)	NCBI		Celera
Cytogenetic Map	1	q22	NCBI

Klk15
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955559	450,472 - 455,179 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955559	450,472 - 455,179 (+)	NCBI	ChiLan1.0	ChiLan1.0

KLK15
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	56,893,627 - 56,896,854 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	58,814,120 - 58,820,334 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	47,790,502 - 47,797,145 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	56,683,713 - 56,689,939 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	56,683,713 - 56,689,939 (-)	Ensembl	panpan1.1		panPan2

LOC480822
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	106,005,601 - 106,007,583 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	106,019,171 - 106,022,517 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	105,575,838 - 105,590,238 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	106,513,163 - 106,527,567 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	106,514,790 - 106,519,584 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	106,185,727 - 106,200,119 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	105,828,576 - 105,833,559 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	106,645,789 - 106,667,203 (+)	NCBI		UU_Cfam_GSD_1.0

KLK15
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	55,578,472 - 55,584,419 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	55,578,476 - 55,586,397 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	51,477,332 - 51,483,294 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KLK15
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	43,873,709 - 43,885,350 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	43,873,614 - 43,885,624 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666073	23,894,978 - 23,903,041 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Klk15
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624832	3,862,479 - 3,867,187 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624832	3,862,479 - 3,867,674 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013365870	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010004409	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000029193 ⟹ ENSSTOP00000022378

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936889	539,403 - 544,136 (-)	Ensembl

RefSeq Acc Id:

XM_013365870 ⟹ XP_013221324

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024409349	22,663,277 - 22,665,277 (-)	NCBI
SpeTri2.0	NW_004936889	539,195 - 544,136 (-)	NCBI

Sequence:

show sequence

ATGTGGCTTCTGCTCATCTTCTCCATCCTGGTGACATCTGCAGCCCAGGATAGAGACAAGGCGC
TGGAAGGGGAGGAGTGTGTGCCCCACTCCCAGCCATGGCAAGTGGCCCTCTTCGAGCGTGGGCG
CTTCAACTGCGGGGCTTCCCTCATCTCCCCACGCTGGGTGCTCTCTGCTGCACACTGCCTCACC
CGCTTCATGAGAGTGCGCCTGGGTGAGCACAATCTGCGCAAGCGTGATGGCCCCGAGCAACTGC
GGATGGTTTCTCGCATCATCCCCCACCCGCAGTACGAAGCACGCAGCCACCGCCATGACGTCAT
GTTGGTGCGGCTAGCCAGACCTGCGCGTCTGACCCCCCAGGTGCGCCCAGTGGCTCTGCCCACC
CGTTGCCCCGACCCAGGAGAGGCCTGCAGGGTGTCTGGCTGGGGCCTGGTGTCCAACAAGGAGT
CCGGGACCACAGGAAGCCCTGAGTCTCAAGTGAGCCTCCCAGACACGCTGCATTGTGCCAACAT
CAGCATCATCTCGGACGCCTCTTGTAACAAGGATTACCCTGGACGCCTGACAAGCGCCATGGTG
TGTGCAGGAGTGGAGGGCGGAGGAACGGACTCCTGCGAGGGTGACTCCGGGGGACCCCTGATCT
GTAGAGGTGCTCTTCAGGGCATTGTGTCCTGGGGTGATGTCCCTTGTGACACTACCACCAAGCC
TGGTGTCTATACCAAAGTCTGCCGCTACCTGAAGTGGATCAGGGAAACCATGAAGAGAAACTGA
CTAATTGGCCTACCTGACTGAGCGGAAGCCTCCAGGGCTGGCCAGCGGTCCCGTCCTGCCCTAC
TAGGCTACTATGTCCCTGTCCTGCCCTGCACCTACTATGTCCCTGTCTAAGTCCCAGATGGTAG
CCAAGGACTTGTCATGCCTGAAGCCAAAGCTGGTGTTCAAGGTCACCTGTTTAACACCAAGATC
AGAGGTTGATTCACAT

hide sequence

Protein Sequences


Protein RefSeqs	XP_013221324	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000022378.2
GenBank Protein	KAG3256598	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_013221324 ⟸ XM_013365870

- UniProtKB:

I3NDD1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MWLLLIFSILVTSAAQDRDKALEGEECVPHSQPWQVALFERGRFNCGASLISPRWVLSAAHCLT
RFMRVRLGEHNLRKRDGPEQLRMVSRIIPHPQYEARSHRHDVMLVRLARPARLTPQVRPVALPT
RCPDPGEACRVSGWGLVSNKESGTTGSPESQVSLPDTLHCANISIISDASCNKDYPGRLTSAMV
CAGVEGGGTDSCEGDSGGPLICRGALQGIVSWGDVPCDTTTKPGVYTKVCRYLKWIRETMKRN

hide sequence

RefSeq Acc Id:

ENSSTOP00000022378 ⟸ ENSSTOT00000029193

Protein Domains

Peptidase S1

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000022412	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000029193.2	UniProtKB/TrEMBL
Gene3D-CATH	2.40.10.10	UniProtKB/TrEMBL
InterPro	Peptidase_S1_PA	UniProtKB/TrEMBL
	Peptidase_S1_PA_chymotrypsin	UniProtKB/TrEMBL
	Peptidase_S1A	UniProtKB/TrEMBL
	Trypsin_dom	UniProtKB/TrEMBL
	TRYPSIN_HIS	UniProtKB/TrEMBL
	TRYPSIN_SER	UniProtKB/TrEMBL
NCBI Gene	Klk15	ENTREZGENE
PANTHER	KALLIKREIN-15	UniProtKB/TrEMBL
	KALLIKREIN-RELATED	UniProtKB/TrEMBL
Pfam	Trypsin	UniProtKB/TrEMBL
PRINTS	CHYMOTRYPSIN	UniProtKB/TrEMBL
PROSITE	TRYPSIN_DOM	UniProtKB/TrEMBL
	TRYPSIN_HIS	UniProtKB/TrEMBL
	TRYPSIN_SER	UniProtKB/TrEMBL
SMART	Tryp_SPc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF50494	UniProtKB/TrEMBL
UniProt	I3NDD1	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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