LOC101972165 (myosin-7) - Rat Genome Database

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Advanced Search (OLGA)
Gene: LOC101972165 (myosin-7) Ictidomys tridecemlineatus
Analyze
Symbol: LOC101972165 (Ensembl: MYH7)
Name: myosin-7
RGD ID: 12718128
Description: ENCODES a protein that exhibits ATP binding (ortholog); ATP hydrolysis activity (ortholog); identical protein binding (ortholog); INVOLVED IN cardiac muscle hypertrophy in response to stress (ortholog); cellular response to 3,3',5-triiodo-L-thyronine (ortholog); cellular response to angiotensin (ortholog); ASSOCIATED WITH adenosine deaminase deficiency (ortholog); arrhythmogenic right ventricular cardiomyopathy (ortholog); arrhythmogenic right ventricular dysplasia 9 (ortholog); FOUND IN muscle myosin complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Myh7; myosin heavy chain 7
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864035,397,460 - 35,421,544 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936722969,384 - 991,129 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936722967,443 - 991,530 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
adenosine deaminase deficiency  (ISO)
arrhythmogenic right ventricular cardiomyopathy  (ISO)
arrhythmogenic right ventricular dysplasia 9  (ISO)
atrial fibrillation  (ISO)
atrial heart septal defect  (ISO)
autism spectrum disorder  (ISO)
autosomal dominant hyaline body myopathy  (ISO)
autosomal recessive hyaline body myopathy  (ISO)
Brain-Lung-Thyroid Syndrome  (ISO)
Camptocormia  (ISO)
Cardiac Arrhythmias  (ISO)
Cardiac Conduction Defect  (ISO)
Cardiomegaly  (ISO)
cardiomyopathy  (ISO)
combined immunodeficiency  (ISO)
combined T cell and B cell immunodeficiency  (ISO)
congenital heart disease  (ISO)
congenital myopathy  (ISO)
congenital myopathy 4A  (ISO)
congenital structural myopathy  (ISO)
congestive heart failure  (ISO)
coronary stenosis  (ISO)
craniosynostosis  (ISO)
Craniosynostosis 4  (ISO)
diastolic heart failure  (ISO)
dilated cardiomyopathy  (ISO)
dilated cardiomyopathy 1A  (ISO)
dilated cardiomyopathy 1B  (ISO)
dilated cardiomyopathy 1H  (ISO)
dilated cardiomyopathy 1S  (ISO)
Dilated Cardiomyopathy with Left Ventricular Noncompaction  (ISO)
distal myopathy  (ISO)
distal myopathy 1  (ISO)
Dyspnea  (ISO)
Ebstein anomaly  (ISO)
Endotoxemia  (ISO)
familial hypertrophic cardiomyopathy  (ISO)
Familial Ventricular Tachycardia  (ISO)
first-degree atrioventricular block  (ISO)
genetic disease  (ISO)
Heart Block  (ISO)
heart disease  (ISO)
hyaline body myopathy  (ISO)
hypertension  (ISO)
hypertrophic cardiomyopathy  (ISO)
hypertrophic cardiomyopathy 1  (ISO)
hypertrophic cardiomyopathy 14  (ISO)
hypertrophic cardiomyopathy 2  (ISO)
hypertrophic cardiomyopathy 4  (ISO)
hypoplastic left heart syndrome  (ISO)
hypothyroidism  (ISO)
intrinsic cardiomyopathy  (ISO)
Leber congenital amaurosis  (ISO)
Left Ventricular Hypertrophy  (ISO)
left ventricular noncompaction  (ISO)
long QT syndrome  (ISO)
lymphopenia  (ISO)
lysinuric protein intolerance  (ISO)
Metabolic Side Effects of Drugs and Substances  (ISO)
microcephalic osteodysplastic primordial dwarfism type I  (ISO)
muscular disease  (ISO)
myocardial infarction  (ISO)
myopathy  (ISO)
neuromuscular disease  (ISO)
pericarditis  (ISO)
restrictive cardiomyopathy  (ISO)
scapuloperoneal myopathy  (ISO)
severe combined immunodeficiency  (ISO)
Specific Granule Deficiency  (ISO)
Sudden Cardiac Death  (ISO)
Sudden Death  (ISO)
Ventricular Fibrillation  (ISO)
Ventricular Fibrillation, Paroxysmal Familial, 1  (ISO)
Ventricular Tachycardia  (ISO)
Wolff-Parkinson-White syndrome  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
LOC101972165
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864035,397,460 - 35,421,544 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936722969,384 - 991,129 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936722967,443 - 991,530 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYH7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381423,412,740 - 23,435,660 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1423,412,740 - 23,435,660 (-)EnsemblGRCh38hg38GRCh38
GRCh371423,881,949 - 23,904,869 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361422,951,787 - 22,974,710 (-)NCBINCBI36Build 36hg18NCBI36
Build 341422,951,788 - 22,974,690NCBI
Celera143,744,643 - 3,767,558 (-)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef143,998,386 - 4,019,919 (-)NCBIHuRef
CHM1_11423,880,619 - 23,902,164 (-)NCBICHM1_1
T2T-CHM13v2.01417,613,744 - 17,636,658 (-)NCBIT2T-CHM13v2.0
Myh7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391455,208,141 - 55,232,083 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1455,208,141 - 55,232,083 (-)EnsemblGRCm39 Ensembl
GRCm381454,970,684 - 54,994,626 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1454,970,684 - 54,994,626 (-)EnsemblGRCm38mm10GRCm38
MGSCv371455,589,525 - 55,613,386 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361453,924,897 - 53,948,620 (-)NCBIMGSCv36mm8
Celera1452,776,617 - 52,800,228 (-)NCBICelera
Cytogenetic Map14C3NCBI
cM Map1428.01NCBI
Myh7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81532,416,525 - 32,439,851 (-)NCBIGRCr8
mRatBN7.21528,446,550 - 28,469,888 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1528,446,550 - 28,468,217 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1530,292,350 - 30,313,937 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01531,439,549 - 31,461,136 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01529,682,125 - 29,703,795 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01533,605,769 - 33,657,761 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1533,634,422 - 33,656,089 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01537,512,803 - 37,544,317 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41533,072,928 - 33,094,595 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1528,024,223 - 28,045,877 (-)NCBICelera
Cytogenetic Map15p13NCBI
LOC100978529
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21524,843,945 - 24,866,994 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11424,060,435 - 24,083,484 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0144,231,344 - 4,254,295 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11422,325,814 - 22,348,763 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1422,325,812 - 22,348,763 (-)Ensemblpanpan1.1panPan2
MYH7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.183,660,155 - 3,677,650 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl83,629,585 - 3,792,725 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha83,578,091 - 3,599,679 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.083,767,766 - 3,789,981 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl83,736,980 - 3,815,024 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.183,459,417 - 3,479,285 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.083,520,889 - 3,540,771 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.083,782,913 - 3,802,783 (-)NCBIUU_Cfam_GSD_1.0
MYH7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl775,648,442 - 75,673,225 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1775,650,841 - 75,672,908 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2781,066,278 - 81,088,335 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103231480
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12923,783,610 - 23,804,981 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2923,783,557 - 23,799,771 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366746111,909 - 30,900 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005342988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010003700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSSTOT00000002616   ⟹   ENSSTOP00000002340
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936722969,384 - 991,129 (+)Ensembl
RefSeq Acc Id: XM_005342988   ⟹   XP_005343045
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864035,397,460 - 35,421,544 (-)NCBI
SpeTri2.0NW_004936722967,443 - 991,530 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005343045 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000002340.3
RefSeq Acc Id: XP_005343045   ⟸   XM_005342988
- UniProtKB: I3M0R9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSTOP00000002340   ⟸   ENSSTOT00000002616
Protein Domains
Myosin motor   Myosin N-terminal SH3-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000002580 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000002616.3 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.820 UniProtKB/TrEMBL
  1.20.5.340 UniProtKB/TrEMBL
  1.20.5.370 UniProtKB/TrEMBL
  1.20.5.4820 UniProtKB/TrEMBL
  1.20.58.530 UniProtKB/TrEMBL
  2.30.30.360 UniProtKB/TrEMBL
  3.40.850.10 UniProtKB/TrEMBL
  6.10.250.2420 UniProtKB/TrEMBL
  Myosin VI head, motor domain, U50 subdomain UniProtKB/TrEMBL
InterPro Kinesin_motor_dom_sf UniProtKB/TrEMBL
  Myosin_head_motor_dom UniProtKB/TrEMBL
  Myosin_N UniProtKB/TrEMBL
  Myosin_S1_N UniProtKB/TrEMBL
  Myosin_tail UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  XRCC4-like_C UniProtKB/TrEMBL
NCBI Gene Myh7 ENTREZGENE
PANTHER MYOSIN HEAVY CHAIN, NON-MUSCLE UniProtKB/TrEMBL
  MYOSIN-7 UniProtKB/TrEMBL
Pfam Myosin_head UniProtKB/TrEMBL
  Myosin_N UniProtKB/TrEMBL
  Myosin_tail_1 UniProtKB/TrEMBL
PRINTS MYOSINHEAVY UniProtKB/TrEMBL
PROSITE MYOSIN_MOTOR UniProtKB/TrEMBL
  PS50096 UniProtKB/TrEMBL
  SH3_LIKE UniProtKB/TrEMBL
SMART MYSc UniProtKB/TrEMBL
Superfamily-SCOP Myosin rod fragments UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt I3M0R9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-07-13 LOC101972165  myosin-7  Myh7  myosin heavy chain 7  Symbol and/or name change 5135510 APPROVED