Nars2 (asparaginyl-tRNA synthetase 2, mitochondrial) - Rat Genome Database

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Gene: Nars2 (asparaginyl-tRNA synthetase 2, mitochondrial) Ictidomys tridecemlineatus
Analyze
Symbol: Nars2
Name: asparaginyl-tRNA synthetase 2, mitochondrial
RGD ID: 12717825
Description: ENCODES a protein that exhibits aminoacyl-tRNA ligase activity (inferred); asparagine-tRNA ligase activity (inferred); ATP binding (inferred); INVOLVED IN asparaginyl-tRNA aminoacylation (inferred); ASSOCIATED WITH autosomal recessive nonsyndromic deafness 94 (ortholog); combined oxidative phosphorylation deficiency 1 (ortholog); combined oxidative phosphorylation deficiency 24 (ortholog); FOUND IN cytosol (inferred); mitochondrion (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: asparaginyl-tRNA synthetase 2, mitochondrial (putative); probable asparagine--tRNA ligase, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494765,367,635 - 65,508,517 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364986,972,180 - 7,108,116 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364986,967,277 - 7,108,130 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA)
mitochondrion  (IEA)
nucleoplasm  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Nars2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494765,367,635 - 65,508,517 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364986,972,180 - 7,108,116 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364986,967,277 - 7,108,130 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NARS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381178,435,968 - 78,574,864 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1178,435,620 - 78,575,194 (-)EnsemblGRCh38hg38GRCh38
GRCh371178,147,014 - 78,285,909 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361177,824,886 - 77,963,367 (-)NCBINCBI36Build 36hg18NCBI36
Celera1175,455,482 - 75,594,400 (-)NCBICelera
Cytogenetic Map11q14.1NCBI
HuRef1174,444,114 - 74,583,005 (-)NCBIHuRef
CHM1_11178,030,151 - 78,168,915 (-)NCBICHM1_1
T2T-CHM13v2.01178,369,261 - 78,508,161 (-)NCBIT2T-CHM13v2.0
Nars2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39796,600,698 - 96,725,606 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl796,600,712 - 96,713,965 (+)EnsemblGRCm39 Ensembl
GRCm38796,950,839 - 97,064,758 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl796,951,505 - 97,064,758 (+)EnsemblGRCm38mm10GRCm38
MGSCv377104,100,037 - 104,213,268 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36796,826,719 - 96,939,947 (+)NCBIMGSCv36mm8
MGSCv36786,687,459 - 86,800,685 (+)NCBIMGSCv36mm8
Cytogenetic Map7E1NCBI
cM Map753.13NCBI
Nars2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81160,711,680 - 160,823,311 (+)NCBIGRCr8
mRatBN7.21151,300,446 - 151,412,086 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1151,300,467 - 151,413,521 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1159,283,727 - 159,398,167 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01166,463,898 - 166,578,341 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01159,337,376 - 159,451,835 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01161,922,132 - 162,035,817 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1161,922,141 - 162,034,700 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01168,135,529 - 168,218,633 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41154,216,134 - 154,299,695 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11154,294,448 - 154,407,988 (+)NCBI
Celera1149,405,605 - 149,488,192 (+)NCBICelera
Cytogenetic Map1q32NCBI
Nars2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541413,410,741 - 13,528,423 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541413,410,751 - 13,528,014 (+)NCBIChiLan1.0ChiLan1.0
NARS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2979,369,492 - 79,507,715 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11180,413,341 - 80,551,532 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01173,496,423 - 73,634,623 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11177,117,668 - 77,255,037 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1177,117,668 - 77,255,037 (-)Ensemblpanpan1.1panPan2
NARS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12120,277,707 - 20,413,624 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2120,277,507 - 20,606,736 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2120,172,632 - 20,308,737 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02120,480,690 - 20,616,549 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2120,480,413 - 20,624,453 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12120,258,355 - 20,393,504 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02120,472,646 - 20,608,490 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02120,396,339 - 20,532,773 (+)NCBIUU_Cfam_GSD_1.0
NARS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl912,867,686 - 13,010,887 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1912,869,347 - 13,010,897 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2914,153,526 - 14,294,377 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NARS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1169,647,713 - 69,778,390 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl169,643,531 - 69,778,361 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604355,958,968 - 56,097,658 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nars2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248631,446,081 - 1,584,003 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248631,439,257 - 1,583,877 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000030055   ⟹   ENSSTOP00000023292
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364986,972,180 - 7,108,116 (-)Ensembl
RefSeq Acc Id: XM_005323249   ⟹   XP_005323306
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494765,373,812 - 65,508,516 (-)NCBI
SpeTri2.0NW_0049364986,973,446 - 7,108,129 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021725133   ⟹   XP_021580808
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494765,367,635 - 65,508,517 (-)NCBI
SpeTri2.0NW_0049364986,967,277 - 7,108,130 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040284998   ⟹   XP_040140932
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494765,367,635 - 65,508,517 (-)NCBI
RefSeq Acc Id: XM_040284999   ⟹   XP_040140933
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494765,368,904 - 65,508,517 (-)NCBI
RefSeq Acc Id: XM_040285000   ⟹   XP_040140934
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494765,373,812 - 65,493,330 (-)NCBI
Protein Sequences
Protein RefSeqs XP_005323306 (Get FASTA)   NCBI Sequence Viewer  
  XP_021580808 (Get FASTA)   NCBI Sequence Viewer  
  XP_040140932 (Get FASTA)   NCBI Sequence Viewer  
  XP_040140933 (Get FASTA)   NCBI Sequence Viewer  
  XP_040140934 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000023292.2
Reference Protein Sequences
RefSeq Acc Id: XP_005323306   ⟸   XM_005323249
- Peptide Label: isoform X1
- UniProtKB: I3NFZ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021580808   ⟸   XM_021725133
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_040140932   ⟸   XM_040284998
- Peptide Label: isoform X3
RefSeq Acc Id: XP_040140933   ⟸   XM_040284999
- Peptide Label: isoform X3
RefSeq Acc Id: XP_040140934   ⟸   XM_040285000
- Peptide Label: isoform X4
RefSeq Acc Id: ENSSTOP00000023292   ⟸   ENSSTOT00000030055
Protein Domains
Aminoacyl-transfer RNA synthetases class-II family


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000019758 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000030055.2 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.140 UniProtKB/TrEMBL
InterPro Aa-tRNA-synt_II UniProtKB/TrEMBL
  aa-tRNA-synth_II UniProtKB/TrEMBL
  aa-tRNA-synth_II/BPL/LPL UniProtKB/TrEMBL
  Asn-tRNA-ligase UniProtKB/TrEMBL
  Asp/Asn-tRNA-synth_IIb UniProtKB/TrEMBL
  NA-bd_OB-fold UniProtKB/TrEMBL
  NA-bd_OB_tRNA UniProtKB/TrEMBL
NCBI Gene Nars2 ENTREZGENE
PANTHER ASPARAGINE--TRNA LIGASE, MITOCHONDRIAL-RELATED UniProtKB/TrEMBL
  ASPARTYL/LYSYL-TRNA SYNTHETASE UniProtKB/TrEMBL
Pfam tRNA-synt_2 UniProtKB/TrEMBL
  tRNA_anti-codon UniProtKB/TrEMBL
PRINTS TRNASYNTHASP UniProtKB/TrEMBL
PROSITE AA_TRNA_LIGASE_II UniProtKB/TrEMBL
Superfamily-SCOP SSF50249 UniProtKB/TrEMBL
  SSF55681 UniProtKB/TrEMBL
UniProt I3NFZ5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-09-26 Nars2  asparaginyl-tRNA synthetase 2, mitochondrial    asparaginyl-tRNA synthetase 2, mitochondrial (putative)  Symbol and/or name change 5135510 APPROVED