Synj2 (synaptojanin 2) - Rat Genome Database

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Gene: Synj2 (synaptojanin 2) Ictidomys tridecemlineatus
Analyze
Symbol: Synj2
Name: synaptojanin 2
RGD ID: 12711739
Description: ENCODES a protein that exhibits inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity (ortholog); inositol-1,4,5-trisphosphate 5-phosphatase activity (ortholog); phosphatidylinositol monophosphate phosphatase activity (ortholog); INVOLVED IN inositol phosphate catabolic process (ortholog); phosphatidylinositol dephosphorylation (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); chromosome 6q24-q25 deletion syndrome (ortholog); genetic disease (ortholog); FOUND IN axon terminus (ortholog); cytoplasmic microtubule (ortholog); presynapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: synaptojanin-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946142,595,865 - 142,659,959 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364899,848,062 - 9,908,760 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364899,848,070 - 9,911,952 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Synj2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946142,595,865 - 142,659,959 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364899,848,062 - 9,908,760 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364899,848,070 - 9,911,952 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SYNJ2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386157,981,296 - 158,099,176 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6157,981,863 - 158,099,176 (+)EnsemblGRCh38hg38GRCh38
GRCh376158,402,895 - 158,520,208 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366158,322,907 - 158,439,556 (+)NCBINCBI36Build 36hg18NCBI36
Build 346158,373,327 - 158,489,977NCBI
Celera6159,051,752 - 159,169,058 (+)NCBICelera
Cytogenetic Map6q25.3NCBI
HuRef6155,875,294 - 155,992,255 (+)NCBIHuRef
CHM1_16158,665,133 - 158,782,434 (+)NCBICHM1_1
T2T-CHM13v2.06159,227,492 - 159,345,318 (+)NCBIT2T-CHM13v2.0
Synj2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39175,991,555 - 6,106,041 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl175,991,555 - 6,094,565 (+)EnsemblGRCm39 Ensembl
GRCm38175,941,280 - 6,055,766 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl175,941,280 - 6,044,290 (+)EnsemblGRCm38mm10GRCm38
MGSCv37175,941,280 - 6,044,290 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36175,932,123 - 6,000,772 (+)NCBIMGSCv36mm8
Celera176,513,365 - 6,582,071 (+)NCBICelera
Cytogenetic Map17A1NCBI
cM Map173.59NCBI
Synj2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8148,923,742 - 49,027,153 (+)NCBIGRCr8
mRatBN7.2146,518,594 - 46,621,919 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl146,518,709 - 46,633,687 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx147,069,005 - 47,165,022 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0153,056,255 - 53,152,284 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0147,144,430 - 47,240,455 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0146,835,922 - 46,932,544 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl146,835,971 - 46,932,529 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0148,140,566 - 48,236,043 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4140,763,794 - 40,818,491 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1140,766,738 - 40,821,418 (+)NCBI
Celera142,211,492 - 42,305,219 (+)NCBICelera
Cytogenetic Map1q11NCBI
Synj2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554394,290,238 - 4,400,775 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554394,305,630 - 4,400,775 (-)NCBIChiLan1.0ChiLan1.0
SYNJ2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25178,095,787 - 178,228,422 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16175,999,205 - 176,128,735 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06155,881,818 - 156,011,416 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16157,940,846 - 158,058,462 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6157,940,179 - 158,055,662 (+)Ensemblpanpan1.1panPan2
SYNJ2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1147,506,925 - 47,582,353 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl147,483,942 - 47,579,831 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha148,327,920 - 48,426,329 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0147,669,938 - 47,768,899 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl147,669,793 - 47,771,015 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1147,548,877 - 47,647,228 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0147,418,371 - 47,516,811 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0147,977,352 - 48,075,852 (+)NCBIUU_Cfam_GSD_1.0
SYNJ2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl19,014,551 - 9,109,103 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.119,014,206 - 9,109,050 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2111,136,293 - 11,232,123 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SYNJ2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11385,579,457 - 85,695,694 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1385,580,392 - 85,692,908 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604057,949,365 - 58,065,977 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Synj2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624785145,228 - 266,022 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624785157,455 - 265,926 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000016478   ⟹   ENSSTOP00000014748
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364899,848,062 - 9,908,760 (+)Ensembl
RefSeq Acc Id: XM_021723933   ⟹   XP_021579608
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404946142,595,874 - 142,659,959 (+)NCBI
SpeTri2.0NW_0049364899,848,070 - 9,911,952 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021723934   ⟹   XP_021579609
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404946142,595,872 - 142,659,959 (+)NCBI
SpeTri2.0NW_0049364899,848,070 - 9,911,952 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021723935   ⟹   XP_021579610
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404946142,595,868 - 142,656,125 (+)NCBI
SpeTri2.0NW_0049364899,848,070 - 9,908,043 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021723936   ⟹   XP_021579611
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404946142,595,865 - 142,656,125 (+)NCBI
SpeTri2.0NW_0049364899,848,070 - 9,908,043 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040283480   ⟹   XP_040139414
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404946142,595,874 - 142,659,959 (+)NCBI
RefSeq Acc Id: XM_040283481   ⟹   XP_040139415
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404946142,595,873 - 142,659,959 (+)NCBI
RefSeq Acc Id: XM_040283482   ⟹   XP_040139416
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404946142,595,872 - 142,659,959 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021579608   ⟸   XM_021723933
- Peptide Label: isoform X1
- UniProtKB: I3MRL9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021579609   ⟸   XM_021723934
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_021579610   ⟸   XM_021723935
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_021579611   ⟸   XM_021723936
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_040139416   ⟸   XM_040283482
- Peptide Label: isoform X5
RefSeq Acc Id: XP_040139415   ⟸   XM_040283481
- Peptide Label: isoform X3
RefSeq Acc Id: XP_040139414   ⟸   XM_040283480
- Peptide Label: isoform X2
RefSeq Acc Id: ENSSTOP00000014748   ⟸   ENSSTOT00000016478
Protein Domains
RRM   SAC


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000016474 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000016478.3 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
  3.60.10.10 UniProtKB/TrEMBL
InterPro DUF1866 UniProtKB/TrEMBL
  Endo/exonu/phosph_ase_sf UniProtKB/TrEMBL
  IP5 UniProtKB/TrEMBL
  IPPc UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_dom UniProtKB/TrEMBL
  SAC_dom UniProtKB/TrEMBL
  SYNJ2_RRM UniProtKB/TrEMBL
NCBI Gene Synj2 ENTREZGENE
PANTHER INOSITOL 5-PHOSPHATASE UniProtKB/TrEMBL
  PTHR11200:SF148 UniProtKB/TrEMBL
Pfam DUF1866 UniProtKB/TrEMBL
  Syja_N UniProtKB/TrEMBL
PROSITE RRM UniProtKB/TrEMBL
  SAC UniProtKB/TrEMBL
SMART DUF1866 UniProtKB/TrEMBL
  IPPc UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/TrEMBL
  SSF56219 UniProtKB/TrEMBL
UniProt I3MRL9 ENTREZGENE, UniProtKB/TrEMBL