Bdkrb1 (bradykinin receptor B1) - Rat Genome Database

Name: Bdkrb1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Bdkrb1 (bradykinin receptor B1) Ictidomys tridecemlineatus

Analyze

Symbol:

Bdkrb1

Name:

bradykinin receptor B1

RGD ID:

12708227

Description:

ENCODES a protein that exhibits bradykinin receptor activity (ortholog); peptide binding (ortholog); INVOLVED IN cell migration (ortholog); cyclooxygenase pathway (ortholog); inflammatory response (ortholog); PARTICIPATES IN G protein mediated signaling pathway via Galphai family; G protein mediated signaling pathway via Galphaq family; kallikrein-kinin cascade pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); Diabetes Complications (ortholog); diabetic angiopathy (ortholog); FOUND IN membrane (ortholog); neuron projection (ortholog); plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

B1 bradykinin receptor

RGD Orthologs

Human

Mouse

Rat

Chinchilla

Bonobo

Dog

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	9,515,392 - 9,516,560 (-)	NCBI
SpeTri2.0	NW_004936604	551,774 - 567,014 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute myeloid leukemia (ISO)

Diabetes Complications (ISO)

diabetic angiopathy (ISO)

diabetic neuropathy (ISO)

diabetic retinopathy (ISO)

Edema (ISO)

end stage renal disease (ISO)

epilepsy (ISO)

essential thrombocythemia (ISO)

Experimental Arthritis (ISO)

Experimental Diabetes Mellitus (ISO)

Fibrosis (ISO)

focal segmental glomerulosclerosis (ISO)

glomerulonephritis (ISO)

Hyperalgesia (ISO)

hypertension (ISO)

Inflammation (ISO)

Insulin Resistance (ISO)

Kidney Reperfusion Injury (ISO)

Left Ventricular Hypertrophy (ISO)

Microvascular Angina (ISO)

myelofibrosis (ISO)

myocardial infarction (ISO)

nephritis (ISO)

obesity (ISO)

Overactive Urinary Bladder (ISO)

Pain (ISO)

pleurisy (ISO)

pulmonary fibrosis (ISO)

renal fibrosis (ISO)

rhinitis (ISO)

sciatic neuropathy (ISO)

Splenomegaly (ISO)

temporal lobe epilepsy (ISO)

Vascular System Injuries (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell migration (ISO)

cyclooxygenase pathway (ISO)

inflammatory response (ISO)

negative regulation of blood pressure (ISO)

negative regulation of cell growth (ISO)

negative regulation of protein phosphorylation (ISO)

positive regulation of leukocyte migration (ISO)

positive regulation of release of sequestered calcium ion into cytosol (ISO)

protein kinase C-activating G protein-coupled receptor signaling pathway (ISO)

response to lipopolysaccharide (ISO)

sensory perception of pain (ISO)

smooth muscle relaxation of the bladder outlet (ISO)

Cellular Component

membrane (ISO)

neuron projection (ISO)

plasma membrane (ISO)

Molecular Function

bradykinin receptor activity (ISO)

peptide binding (ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

G protein mediated signaling pathway via Galphai family (ISO)

G protein mediated signaling pathway via Galphaq family (ISO)

kallikrein-kinin cascade pathway (ISO)

kinin signaling pathway (ISO)

References

Genomics

Comparative Map Data

Bdkrb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	9,515,392 - 9,516,560 (-)	NCBI
SpeTri2.0	NW_004936604	551,774 - 567,014 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

BDKRB1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	96,256,210 - 96,264,763 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	14	96,256,210 - 96,268,967 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	96,722,547 - 96,731,100 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	95,792,312 - 95,800,853 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	14	95,792,311 - 95,800,851	NCBI
Celera	14	76,778,278 - 76,786,817 (+)	NCBI
Cytogenetic Map	14	q32.2	NCBI
HuRef	14	76,907,652 - 76,916,201 (+)	NCBI		HuRef
CHM1_1	14	96,661,476 - 96,670,026 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	90,487,459 - 90,496,013 (+)	NCBI

Bdkrb1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	105,570,350 - 105,571,770 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	12	105,569,344 - 105,571,687 (+)	Ensembl
GRCm38	12	105,604,091 - 105,605,511 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	105,603,085 - 105,605,428 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	106,842,301 - 106,843,638 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	12	106,005,141 - 106,006,478 (+)	NCBI			mm8
Celera	12	106,838,703 - 106,840,040 (+)	NCBI		Celera
Cytogenetic Map	12	E	NCBI

Bdkrb1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	6	124,510,827 - 124,514,475 (+)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	6	124,510,870 - 124,513,747 (+)	Ensembl
Rnor_6.0	6	129,437,423 - 129,441,553 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	129,438,158 - 129,440,574 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	138,631,450 - 138,633,866 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	129,760,129 - 129,762,545 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	6	129,763,875 - 129,766,292 (+)	NCBI
Celera	6	122,077,962 - 122,080,378 (+)	NCBI		Celera
RH 3.4 Map	6	821.1	RGD
Cytogenetic Map	6	q32	NCBI

Bdkrb1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955438	16,500,633 - 16,501,691 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955438	16,500,219 - 16,505,394 (-)	NCBI	ChiLan1.0	ChiLan1.0

BDKRB1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	14	96,208,312 - 96,221,049 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
Mhudiblu_PPA_v0	14	76,885,923 - 76,894,456 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

BDKRB1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	65,017,655 - 65,028,899 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	64,541,610 - 64,542,662 (+)	NCBI
ROS_Cfam_1.0	8	65,289,047 - 65,301,253 (+)	NCBI
ROS_Cfam_1.0 Ensembl	8	65,297,113 - 65,298,165 (+)	Ensembl
UMICH_Zoey_3.1	8	64,970,187 - 64,971,239 (+)	NCBI
UNSW_CanFamBas_1.0	8	65,031,504 - 65,032,556 (+)	NCBI
UU_Cfam_GSD_1.0	8	65,355,171 - 65,356,223 (+)	NCBI

BDKRB1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	117,491,350 - 117,492,410 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	117,491,350 - 117,492,410 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	124,701,695 - 124,749,780 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

BDKRB1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	74,136,464 - 74,146,668 (+)	NCBI	ChlSab1.1		chlSab2
ChlSab1.1 Ensembl	24	74,145,531 - 74,146,592 (+)	Ensembl	ChlSab1.1		chlSab2
Vero_WHO_p1.0	NW_023666053	61,287,030 - 61,297,919 (+)	NCBI	Vero_WHO_p1.0

Bdkrb1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	8,548,356 - 8,549,414 (+)	Ensembl	HetGla_female_1.0		hetGla2
HetGla 1.0	NW_004624734	8,545,707 - 8,549,846 (+)	NCBI	HetGla_female_1.0		hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013362226	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010003700	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

XM_013362226 ⟹ XP_013217680

RefSeq Status:

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	9,515,392 - 9,516,560 (-)	NCBI
SpeTri2.0	NW_004936604	551,774 - 567,014 (+)	NCBI

Sequence:

show sequence

ATGGCCCGGACTCCAGCATCAGGCAGCTTAGAGCCAGGCAGCGCTGCAGCACAAGATGACGTCC
TCAGGAACGGCTCTTTCCAGGAGCCCACCAAGCCCGGCTGCCTGCACCTCATCCGATGCCCCAG
CTCTGCAGAGCGGCTCCTGGAGAGGGCAGAGAAGGGCCCAGGTCGCCCTGCCCGCAGGGGTGGA
GCGGGGATTCAAGCCCTGGCGAGGCGTTTCCACTCCACCGACCTCCAAGCCGGCGGGCGCAGGG
CTGGAGCCGGAGGCTGGGTTCTGGGACTTTCCTCGTCCTCGGAATCCCTGGCCCAGTGGAGCTT
GTGCCACCAACGGCCCCTTCCTGTCCTGGAGCAGCGCTCAGGCCTGCACCTTGGCCAGCAGGTG
GGCTCAGGCCCCCGCCCCACCTGGGGCTCTCTGAATGCCGGGATCCGCCCAGTGATCTGGAGTC
TCCAGTGTAGAGGTCTTTCACTTGTTTTTTTAGGTTGAATCCCAAGTTTGTTTTTGTTTGTTGT
TATTGTGGTGGTTGCTTTTCAGGCTCTTGTCATGACCCTGCATCTCCTCCAGGCGGCAAGCCCC
ACAGAGTTGGGGCTGCTCTGTCCTGTGAGTCTCCAGGATCTTGCAAACGGGGTCATCAAGGCCC
ACCTGTTCATCAGCATCTTCCTGGTGGTGGCCATCAGCCAGGACCGCTACCAGGTGCTGGTACA
CCCCATGGCCAGCCGGAGGCGGCGGAGACGCCGGCAGGCCCAGGCCACCTGTGCGCTCATCTGG
GTGGTGGGGGGCCTCCTGAGCACCCCCACGTTCCTGCTGCGGTCCGTCGAAGCCGTCCCTGAGC
TGAACATCTCCGCCTGCATCCTGCTGCTGCCCCACCAGGCCTGGCACGTGGCTAGGATGGTGGA
GCTGACAGTGCTAGGCTTCCTGCTCCCCCTGGCCGCCATCCTCTTCTTCAACGTGCACATCCTG
GCCTCCCTGCGAGCGCGGGAGGCCGTCGGCAGGGCCCGGTGTGGGGGCCCCAGCGACGGCAAGA
CCACGGCGCTGATCCTGGCGCTCGTGGGGGCCTTCCTGGTGTGCTGGGCGCCCTACCACCTCTT
CGCCTTCCTGGAGTTCCTGTTCCGGGTGGGGGCCGTCCAGGGCTGCTCCTGGGAGGAGCCCATC
GACCTGGGCCTGCAGCTGGCCAACTCCCTGGCCTTCGCCAACAGCTGCCTGAACCCCGTGATCT
TCGTCTTCGTGGGCCGGCTCTTCAGGACCAAGCTCTGGGAGCTTTACAAACGATGCGCCCCCCG
GAGCCTGGCGGCGCTGTCCTCCACCCACAGGAAAGACTGCGGCCCGCTGTCCGGGCGGAGCTGA
AGCAGCAGAGAACGGAGAATCGTGGCCTCCGTTTCGATCCTTCCATCCTCATAAAGACTACGGT
GGTGGTCAGATGACCATCTACCAAATAATGACCCCCCAAGACATCCGGAGCCCGTTTCTAGACC
CTGGGGAGGTTGGTTGACAGGGTAACAGGGACTTTGTAGGTATCATTAAGATGAGGATCTCCGG
GTGGGGAGACGGTCCTGGATTATCCACGTGGCCCAACATAGTCACAGGGTCCTCAGAGTCAGAG
GAGATGTGGGGACACATGCAGAAGTCAGAGCCAGGAGGAAGGAGCCGTGAGCCAAGATTGCAGG
CGCCCTCAGAGGCGGGGCAAACCACGGGGGCAGATCCCCCTGGAGCCTCCAGAAGAGCCTC

hide sequence

Protein Sequences


Protein RefSeqs	XP_013217680	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

XP_013217680 ⟸ XM_013362226

- Sequence:

show sequence

MARTPASGSLEPGSAAAQDDVLRNGSFQEPTKPGCLHLIRCPSSAERLLERAEKGPGRPARRGG
AGIQALARRFHSTDLQAGGRRAGAGGWVLGLSSSSESLAQWSLCHQRPLPVLEQRSGLHLGQQV
GSGPRPTWGSLNAGIRPVIWSLQCRGLSLVFLGXIPSLFLFVVIVVVAFQALVMTLHLLQAASP
TELGLLCPVSLQDLANGVIKAHLFISIFLVVAISQDRYQVLVHPMASRRRRRRRQAQATCALIW
VVGGLLSTPTFLLRSVEAVPELNISACILLLPHQAWHVARMVELTVLGFLLPLAAILFFNVHIL
ASLRAREAVGRARCGGPSDGKTTALILALVGAFLVCWAPYHLFAFLEFLFRVGAVQGCSWEEPI
DLGLQLANSLAFANSCLNPVIFVFVGRLFRTKLWELYKRCAPRSLAALSSTHRKDCGPLSGRS

hide sequence

Additional Information

External Database Links

Database	Acc Id	Source(s)
NCBI Gene	Bdkrb1	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

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Imported Disease Annotations - ClinVar

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