Ephx2 (epoxide hydrolase 2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Ephx2 (epoxide hydrolase 2) Ictidomys tridecemlineatus
Analyze
Symbol: Ephx2
Name: epoxide hydrolase 2
RGD ID: 12707426
Description: ENCODES a protein that exhibits epoxide hydrolase activity (ortholog); magnesium ion binding (ortholog); phosphatase activity (ortholog); INVOLVED IN inflammatory response (ortholog); linoleic acid metabolic process (ortholog); positive regulation of blood pressure (ortholog); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; ASSOCIATED WITH acute kidney failure (ortholog); Acute Lung Injury (ortholog); atherosclerosis (ortholog); FOUND IN cytosol (ortholog); peroxisome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: bifunctional epoxide hydrolase 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049438,193,232 - 8,235,694 (-)NCBI
SpeTri2.0NW_004936675350,357 - 392,919 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Comparative Map Data
Ephx2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049438,193,232 - 8,235,694 (-)NCBI
SpeTri2.0NW_004936675350,357 - 392,919 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EPHX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38827,491,143 - 27,545,564 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl827,490,781 - 27,545,564 (+)EnsemblGRCh38hg38GRCh38
GRCh37827,348,660 - 27,403,081 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36827,404,562 - 27,458,403 (+)NCBINCBI36hg18NCBI36
Build 34827,404,561 - 27,458,403NCBI
Celera826,308,750 - 26,362,585 (+)NCBI
Cytogenetic Map8p21.2-p21.1NCBI
HuRef825,893,566 - 25,947,482 (+)NCBIHuRef
CHM1_1827,550,382 - 27,604,304 (+)NCBICHM1_1
T2T-CHM13v2.0827,768,490 - 27,822,905 (+)NCBI
Ephx2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391466,321,821 - 66,361,971 (-)NCBIGRCm39mm39
GRCm39 Ensembl1466,321,823 - 66,361,949 (-)Ensembl
GRCm381466,084,372 - 66,124,522 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1466,084,374 - 66,124,500 (-)EnsemblGRCm38mm10GRCm38
MGSCv371466,703,214 - 66,743,337 (-)NCBIGRCm37mm9NCBIm37
MGSCv361465,038,487 - 65,078,610 (-)NCBImm8
Celera1463,832,362 - 63,872,496 (-)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1434.36NCBI
Ephx2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21540,289,901 - 40,327,632 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1540,289,902 - 40,327,615 (-)Ensembl
Rnor_6.01542,757,241 - 42,794,211 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1542,757,235 - 42,794,279 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01548,799,823 - 48,836,848 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41545,497,660 - 45,556,101 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11545,513,439 - 45,571,881 (-)NCBI
Celera1539,961,087 - 40,000,936 (-)NCBICelera
Cytogenetic Map15p12NCBI
Ephx2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540349,999,563 - 50,041,572 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540349,999,563 - 50,038,800 (+)NCBIChiLan1.0ChiLan1.0
EPHX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1823,964,094 - 24,017,749 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl823,964,094 - 24,017,749 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0826,761,090 - 26,818,436 (+)NCBIMhudiblu_PPA_v0panPan3
EPHX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12530,045,040 - 30,107,110 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2530,045,291 - 30,107,110 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2530,631,771 - 30,693,869 (-)NCBI
ROS_Cfam_1.02530,235,290 - 30,297,630 (-)NCBI
ROS_Cfam_1.0 Ensembl2530,232,724 - 30,297,642 (-)Ensembl
UMICH_Zoey_3.12530,165,721 - 30,227,963 (-)NCBI
UNSW_CanFamBas_1.02530,046,546 - 30,108,832 (-)NCBI
UU_Cfam_GSD_1.02530,212,901 - 30,275,213 (-)NCBI
EPHX2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1411,216,978 - 11,293,410 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11411,217,125 - 11,293,018 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21412,397,646 - 12,473,595 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EPHX2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1825,603,668 - 25,659,232 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl825,603,735 - 25,659,345 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605216,482,843 - 16,540,761 (-)NCBIVero_WHO_p1.0
Ephx2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475822,221,314 - 22,254,813 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462475822,216,462 - 22,252,467 (+)NCBIHetGla_female_1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005337209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_005337209   ⟹   XP_005337266
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244049438,193,232 - 8,235,694 (-)NCBI
SpeTri2.0NW_004936675350,357 - 392,919 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005337266 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3294319 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005337266   ⟸   XM_005337209
- UniProtKB: I3MG99 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
AB hydrolase-1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000010872 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000009758 ENTREZGENE
  ENSSTOP00000009758.3 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000010876.3 UniProtKB/TrEMBL
Gene3D-CATH 1.10.150.240 UniProtKB/TrEMBL
  3.40.50.1000 UniProtKB/TrEMBL
  3.40.50.1820 UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/TrEMBL
  AB_hydrolase_1 UniProtKB/TrEMBL
  Epox_hydrolase-like UniProtKB/TrEMBL
  HAD-like_sf UniProtKB/TrEMBL
  HAD-SF_hydro_IA UniProtKB/TrEMBL
  HAD_2 UniProtKB/TrEMBL
  HAD_sf UniProtKB/TrEMBL
  PGP-like_dom2 UniProtKB/TrEMBL
NCBI Gene Ephx2 ENTREZGENE
Pfam Abhydrolase_1 UniProtKB/TrEMBL
  HAD_2 UniProtKB/TrEMBL
PRINTS ABHYDROLASE UniProtKB/TrEMBL
  EPOXHYDRLASE UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/TrEMBL
  SSF56784 UniProtKB/TrEMBL
TIGRFAMs HAD-SF-IA-v3 UniProtKB/TrEMBL
UniProt I3MG99 ENTREZGENE, UniProtKB/TrEMBL