Kbtbd7 (kelch repeat and BTB domain containing 7) - Rat Genome Database

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Gene: Kbtbd7 (kelch repeat and BTB domain containing 7) Ictidomys tridecemlineatus
Analyze
Symbol: Kbtbd7
Name: kelch repeat and BTB domain containing 7 (Ensembl:kelch repeat and BTB domain-containing protein 7)
RGD ID: 12706924
Description: INVOLVED IN proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); protein K48-linked ubiquitination (ortholog); regulation of Rac protein signal transduction (ortholog); ASSOCIATED WITH genetic disease (ortholog); Moebius syndrome (ortholog); FOUND IN Cul3-RING ubiquitin ligase complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: kelch repeat and BTB (POZ) domain containing 7; kelch repeat and BTB domain-containing protein 7; LOC101969813
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945151,505,418 - 151,510,168 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936667389,858 - 391,900 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936667389,544 - 394,475 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Kbtbd7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945151,505,418 - 151,510,168 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936667389,858 - 391,900 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936667389,544 - 394,475 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KBTBD7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381341,189,834 - 41,194,569 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1341,189,834 - 41,194,569 (-)EnsemblGRCh38hg38GRCh38
GRCh371341,763,970 - 41,768,705 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361340,663,711 - 40,666,702 (-)NCBINCBI36Build 36hg18NCBI36
Build 341340,663,710 - 40,666,702NCBI
Celera1322,823,146 - 22,826,137 (-)NCBICelera
Cytogenetic Map13q14.11NCBI
HuRef1322,565,790 - 22,568,531 (-)NCBIHuRef
CHM1_11341,733,514 - 41,736,505 (-)NCBICHM1_1
T2T-CHM13v2.01340,408,967 - 40,413,700 (-)NCBIT2T-CHM13v2.0
Kbtbd7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391479,663,951 - 79,668,479 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1479,663,951 - 79,668,476 (+)EnsemblGRCm39 Ensembl
GRCm381479,426,511 - 79,431,039 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1479,426,511 - 79,431,036 (+)EnsemblGRCm38mm10GRCm38
MGSCv371479,826,318 - 79,830,846 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361478,160,666 - 78,165,194 (+)NCBIMGSCv36mm8
Celera1476,926,553 - 76,931,081 (+)NCBICelera
Cytogenetic Map14D3NCBI
cM Map1442.65NCBI
Kbtbd7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81561,215,957 - 61,220,536 (+)NCBIGRCr8
mRatBN7.21554,806,878 - 54,811,457 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1554,806,873 - 54,811,687 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1558,940,309 - 58,944,888 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01560,058,688 - 60,063,267 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01556,883,582 - 56,888,161 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01561,692,041 - 61,696,506 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01565,356,122 - 65,358,216 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1554,390,173 - 54,394,752 (+)NCBICelera
Cytogenetic Map15q12NCBI
Kbtbd7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555184,979,207 - 4,984,721 (+)NCBIChiLan1.0ChiLan1.0
LOC100982140
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21440,711,256 - 40,720,412 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11331,814,975 - 31,824,137 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01322,397,204 - 22,401,999 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11340,986,990 - 40,991,738 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1340,989,363 - 40,991,417 (-)Ensemblpanpan1.1panPan2
KBTBD7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1229,388,467 - 9,391,099 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl229,388,832 - 9,390,871 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha229,384,715 - 9,387,265 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0229,614,481 - 9,617,030 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1229,309,947 - 9,312,500 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0229,359,505 - 9,363,534 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0229,373,998 - 9,378,028 (+)NCBIUU_Cfam_GSD_1.0
KBTBD7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1125,643,719 - 25,646,129 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11125,643,661 - 25,647,662 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21126,571,815 - 26,574,769 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KBTBD7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1319,449,319 - 19,455,117 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl319,451,622 - 19,453,679 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605724,783,638 - 24,788,774 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005336782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000023003   ⟹   ENSSTOP00000019386
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936667389,858 - 391,900 (+)Ensembl
RefSeq Acc Id: XM_005336782   ⟹   XP_005336839
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404945151,505,418 - 151,510,168 (-)NCBI
SpeTri2.0NW_004936667389,544 - 394,475 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005336839 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000019386.2
GenBank Protein KAG3292961 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005336839   ⟸   XM_005336782
- UniProtKB: I3N4U0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000019386   ⟸   ENSSTOT00000023003
Protein Domains
BTB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000029195 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000023003.2 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.420 UniProtKB/TrEMBL
  2.120.10.80 UniProtKB/TrEMBL
InterPro BACK UniProtKB/TrEMBL
  BTB-kelch_protein UniProtKB/TrEMBL
  BTB/POZ_dom UniProtKB/TrEMBL
  KBTB_W-LIR UniProtKB/TrEMBL
  KBTBD6_7_BACK UniProtKB/TrEMBL
  KBTBD6_7_BTB_POZ UniProtKB/TrEMBL
  Kelch-typ_b-propeller UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/TrEMBL
NCBI Gene LOC101969813 ENTREZGENE
PANTHER KELCH PROTEIN UniProtKB/TrEMBL
  KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 7 UniProtKB/TrEMBL
Pfam BACK UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
  KBTB_W-LIR UniProtKB/TrEMBL
  Kelch_1 UniProtKB/TrEMBL
PIRSF Kelch-like_protein_gigaxonin UniProtKB/TrEMBL
PROSITE BTB UniProtKB/TrEMBL
SMART BACK UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
  Kelch UniProtKB/TrEMBL
Superfamily-SCOP SSF117281 UniProtKB/TrEMBL
  SSF54695 UniProtKB/TrEMBL
UniProt I3N4U0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-26 Kbtbd7  kelch repeat and BTB domain containing 7  LOC101969813  kelch repeat and BTB domain-containing protein 7  Symbol and/or name change 5135510 APPROVED