Tubb6 (tubulin beta 6 class V) - Rat Genome Database

Name: Tubb6
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Tubb6 (tubulin beta 6 class V) Ictidomys tridecemlineatus

Analyze

Symbol:

Tubb6

Name:

tubulin beta 6 class V

RGD ID:

12706333

Description:

ENCODES a protein that exhibits GTP binding (inferred); GTPase activity (inferred); structural constituent of cytoskeleton (inferred); INVOLVED IN microtubule cytoskeleton organization (inferred); microtubule-based process (inferred); mitotic cell cycle (inferred); ASSOCIATED WITH chromosome 18p deletion syndrome (ortholog); Congenital Facial Palsy with Ptosis and Velopharyngeal Dysfunction (ortholog); dystonia (ortholog); FOUND IN cytoplasm (inferred); cytoskeleton (inferred); intercellular bridge (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

tubulin beta-6 chain

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TUBB6 (tubulin beta 6 class V)	NCBI	Ortholog
Mus musculus (house mouse):	Tubb6 (tubulin, beta 6 class V)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Tubb6 (tubulin, beta 6 class V)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tubb6 (tubulin beta 6 class V)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TUBB6 (tubulin beta 6 class V)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TUBB6 (tubulin beta 6 class V)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TUBB6 (tubulin beta 6 class V)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TUBB6 (tubulin beta 6 class V)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tubb6 (tubulin beta 6 class V)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404944	964,281 - 976,540 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936626	188,881 - 204,884 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936626	192,191 - 204,827 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

chromosome 18p deletion syndrome (ISO)

Congenital Facial Palsy with Ptosis and Velopharyngeal Dysfunction (ISO)

dystonia (ISO)

Experimental Liver Cirrhosis (ISO)

genetic disease (ISO)

intellectual disability (ISO)

optic atrophy 12 (ISO)

ptosis (ISO)

spastic ataxia 5 (ISO)

spinocerebellar ataxia type 28 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

microtubule cytoskeleton organization (IEA)

microtubule-based process (IEA)

mitotic cell cycle (IEA)

Cellular Component

cytoplasm (IEA)

cytoskeleton (IEA)

intercellular bridge (IEA)

microtubule (IEA)

microtubule cytoskeleton (IEA)

mitotic spindle (IEA)

Molecular Function

GTP binding (IEA)

GTPase activity (IEA)

protein binding (ISO)

structural constituent of cytoskeleton (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Tubb6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404944	964,281 - 976,540 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936626	188,881 - 204,884 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936626	192,191 - 204,827 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TUBB6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	18	12,307,669 - 12,329,826 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	18	12,307,669 - 12,344,320 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	18	12,307,668 - 12,329,825 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	18	12,298,257 - 12,316,568 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	18	12,298,256 - 12,316,567	NCBI
Celera	18	12,191,548 - 12,207,217 (+)	NCBI		Celera
Cytogenetic Map	18	p11.21	NCBI
HuRef	18	12,262,529 - 12,280,345 (+)	NCBI		HuRef
CHM1_1	18	12,307,671 - 12,325,969 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	18	12,470,687 - 12,492,842 (+)	NCBI		T2T-CHM13v2.0

Tubb6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	67,523,801 - 67,535,819 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	67,523,787 - 67,535,819 (+)	Ensembl		GRCm39 Ensembl
GRCm38	18	67,390,731 - 67,402,749 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	67,390,717 - 67,402,749 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	18	67,550,385 - 67,562,403 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	18	67,516,100 - 67,528,118 (+)	NCBI		MGSCv36	mm8
Celera	18	68,666,590 - 68,679,839 (+)	NCBI		Celera
Cytogenetic Map	18	E1	NCBI
cM Map	18	39.96	NCBI

Tubb6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	18	63,213,287 - 63,222,926 (+)	NCBI		GRCr8
mRatBN7.2	18	60,943,394 - 60,953,031 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	60,943,375 - 60,954,418 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	63,013,749 - 63,023,408 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	63,712,512 - 63,722,171 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	61,564,766 - 61,574,430 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	63,130,542 - 63,140,181 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	63,130,542 - 63,140,181 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	62,314,821 - 62,324,460 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	63,919,776 - 63,929,415 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	18	63,992,976 - 64,002,616 (+)	NCBI
Celera	18	59,049,986 - 59,059,625 (+)	NCBI		Celera
Cytogenetic Map	18	q12.1	NCBI

Tubb6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955402	1,070,858 - 1,081,385 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955402	1,071,135 - 1,081,385 (-)	NCBI	ChiLan1.0	ChiLan1.0

TUBB6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	17	25,714,533 - 25,737,628 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	18	11,408,762 - 11,430,225 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	18	1,998,428 - 2,020,202 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	18	17,111,755 - 17,130,003 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

TUBB6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	77,728,876 - 77,746,759 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	77,728,180 - 77,749,270 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	77,129,864 - 77,147,748 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	77,787,314 - 77,805,341 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	77,786,581 - 77,807,852 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	77,483,759 - 77,502,054 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	77,530,924 - 77,549,265 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	77,817,817 - 77,835,721 (+)	NCBI		UU_Cfam_GSD_1.0

TUBB6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	97,229,868 - 97,240,662 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	97,233,639 - 97,240,692 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	90,808,459 - 90,814,364 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TUBB6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	18	70,870,576 - 70,888,560 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	18	70,870,566 - 70,888,099 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	45,896,634 - 45,918,689 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tubb6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624770	19,580,623 - 19,590,617 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005334862	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000028040 ⟹ ENSSTOP00000020726

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936626	188,881 - 204,884 (-)	Ensembl

RefSeq Acc Id:

XM_005334862 ⟹ XP_005334919

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404944	964,281 - 976,540 (-)	NCBI
SpeTri2.0	NW_004936626	192,191 - 204,827 (-)	NCBI

Sequence:

show sequence

AATACGTGCCCAGGGCCGCCCTGGTGGACTTGGAGCCTGGCACCATGGACAGTGTGAGGTCCGG
ACCCTTTGGGCAGCTCTTCCGACCTGATAACTTCATCTTTGGACAGACGGGCGCCGGCAACAAC
TGGGCCAAGGGCCACTACACCGAGGGCGCAGAGCTGGTGGACTCGGTCCTGGATGTGGTGCGCA
AGGAGTGTGAGCACTGCGACTGCCTGCAGGGCTTTCAGCTGACCCACTCGCTGGGCGGCGGCAC
GGGCTCGGGCATGGGCACACTGCTCATCAGCAAGATCCGCGAGGAGTACCCCGACCGCATCATG
AACACCTTCAGCGTCATGCCCTCACCCAAGGTATCTGACACGGTGGTGGAGCCCTACAACGCCA
CGCTGTCGGTGCACCAGCTGGTGGAGAACACGGATGAGACCTACTGCATCGACAACGAGGCGCT
GTACGACATCTGCTTCCGCACCCTCAAGCTGACCACTCCTACCTACGGGGACCTTAACCATCTG
GTGTCGGCCACCATGAGCGGGGTCACCACCTCGCTGCGCTTCCCGGGTCAGCTCAACGCCGACC
TGCGGAAGCTGGCCGTGAACATGGTGCCCTTTCCGCGCCTGCACTTCTTCATGCCGGGCTTCGC
GCCACTGACCGCCCGAGGCAGCCAGCAGTACCGCGCGCTGACAGTGCCCGAGCTCACTCAGCAG
ATGTTCGACGCCAAGAACATGATGGCTGCCTGTGACCCACGCCATGGCCGCTATTTGACCGTGG
CCACCGTTTTCCGTGGCCTCATGTCCATGAAGGAGGTGGATGAGCAGATGCTGGCCATCCAGAA
CAAGAACAGCAGCTACTTTGTGGAGTGGATCCCCAACAACGTCAAGGTGGCTGTGTGCGACATT
CCGCCGCGTGGCCTGAAGATGGCCTCCACCTTTATTGGCAACAGCACAGCCATCCAGGAGCTGT
TCAAGCGCATCTCGGAGCAGTTCTCAGCCATGTTCCGCCGCAAGGCCTTCCTGCATTGGTTCAC
CGGTGAGGGCATGGACGAGATGGAGTTCACCGAGGCCGAGAGCAACATGAACGACTTGGTGTCC
GAATACCAGCAGTACCAGGATGCTACTGTAAACGATGGAGAGGAAGCTTTTGAAGATGAGGAAG
AGGAGATCAATGAATAAAGGCGCTGCCCTGTCCCCAACCAATGTGAAATGCGCGTATTCTTCCT
TTTACCTGATGGTTGTGGAGGGGTGCACTGGTCTCTAGATACATGGGGTAGGTCCCTGGCAAGT
GCAGAGCTGAGAGGTCAGCTGGAATAAAGTCCATATTTTACAATAGCAGAGAATAGGCGGTCCT
ACCCTTTCCAGTCAGCCTAGTGAGATTCTGTACTGGAGCATTTGAGAGAAACAACTAGGGAGCC
ATGAAGGGCTAATGGAAAAAAAACCCACCTGCCAGTATGCATTCAGATATCTGTGAGAACTAGC
AAGGGGCTTAGAAACAGGGTGTTTTCATCCTTCCTGATGAACATTGGAGCTTGCAGTGTTGCCT
TGTTTGAATATACAGTATGGAACTTTGAAACAATCTAGTCATAATAAAACCTATTCTGTTGTGG
CATCCA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005334919	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000020726.2
GenBank Protein	KAG3293487	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005334919 ⟸ XM_005334862

- UniProtKB:

I3N8N0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDSVRSGPFGQLFRPDNFIFGQTGAGNNWAKGHYTEGAELVDSVLDVVRKECEHCDCLQGFQLT
HSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETY
CIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTSLRFPGQLNADLRKLAVNMVPFPRLH
FFMPGFAPLTARGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVATVFRGLMSMKEVDE
QMLAIQNKNSSYFVEWIPNNVKVAVCDIPPRGLKMASTFIGNSTAIQELFKRISEQFSAMFRRK
AFLHWFTGEGMDEMEFTEAESNMNDLVSEYQQYQDATVNDGEEAFEDEEEEINE

hide sequence

RefSeq Acc Id:

ENSSTOP00000020726 ⟸ ENSSTOT00000028040

Protein Domains

Tubulin/FtsZ 2-layer sandwich Tubulin/FtsZ GTPase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000021203	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000028040.2	UniProtKB/TrEMBL
Gene3D-CATH	1.10.287.600	UniProtKB/TrEMBL
	3.30.1330.20	UniProtKB/TrEMBL
	3.40.50.1440	UniProtKB/TrEMBL
InterPro	Beta_tubulin	UniProtKB/TrEMBL
	Tub_FtsZ_C	UniProtKB/TrEMBL
	Tubulin	UniProtKB/TrEMBL
	Tubulin/FtsZ-like_C	UniProtKB/TrEMBL
	Tubulin/FtsZ_2-layer-sand-dom	UniProtKB/TrEMBL
	Tubulin/FtsZ_GTPase_sf	UniProtKB/TrEMBL
	Tubulin_C	UniProtKB/TrEMBL
	Tubulin_CS	UniProtKB/TrEMBL
	Tubulin_FtsZ_GTPase	UniProtKB/TrEMBL
NCBI Gene	Tubb6	ENTREZGENE
PANTHER	PTHR11588	UniProtKB/TrEMBL
	TUBULIN BETA-6 CHAIN	UniProtKB/TrEMBL
Pfam	Tubulin	UniProtKB/TrEMBL
	Tubulin_C	UniProtKB/TrEMBL
PRINTS	BETATUBULIN	UniProtKB/TrEMBL
	TUBULIN	UniProtKB/TrEMBL
PROSITE	TUBULIN	UniProtKB/TrEMBL
SMART	Tubulin	UniProtKB/TrEMBL
	Tubulin_C	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52490	UniProtKB/TrEMBL
	SSF55307	UniProtKB/TrEMBL
UniProt	I3N8N0	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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