Pcsk2 (proprotein convertase subtilisin/kexin type 2)

Advanced Search (OLGA)

Gene: Pcsk2 (proprotein convertase subtilisin/kexin type 2) Ictidomys tridecemlineatus

Analyze

Symbol:

Pcsk2

Name:

proprotein convertase subtilisin/kexin type 2

RGD ID:

12705202

Description:

ENCODES a protein that exhibits endopeptidase activity (inferred); serine-type endopeptidase activity (inferred); serine-type peptidase activity (inferred); INVOLVED IN islet amyloid polypeptide processing (ortholog); peptide hormone processing (ortholog); protein processing (ortholog); PARTICIPATES IN alfentanil pharmacodynamics pathway; bupivacaine pharmacodynamics pathway; buprenorphine pharmacodynamics pathway; ASSOCIATED WITH cataract 33 (ortholog); chronic kidney disease (ortholog); Endotoxemia (ortholog); FOUND IN dendrite (ortholog); neuronal cell body (ortholog); perikaryon (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

neuroendocrine convertase 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	154,177,620 - 154,434,915 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936485	2,608,353 - 2,866,294 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936485	2,611,313 - 2,866,260 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

cataract 33 (ISO)

chronic kidney disease (ISO)

Endotoxemia (ISO)

Experimental Diabetes Mellitus (ISO)

familial hyperinsulinemic hypoglycemia 1 (ISO)

Inflammation (ISO)

myocardial infarction (ISO)

Reperfusion Injury (ISO)

type 2 diabetes mellitus (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

enkephalin processing (IEA)

insulin processing (IEA)

islet amyloid polypeptide processing (ISO)

nervous system development (IEA)

peptide hormone processing (IEA,ISO)

protein autoprocessing (IEA)

protein processing (IEA,ISO)

proteolysis (IEA,ISO)

Cellular Component

dendrite (ISO)

extracellular space (IEA)

intracellular membrane-bounded organelle (IEA)

membrane (IEA)

neuron projection (IEA)

neuronal cell body (ISO)

nucleoplasm (IEA)

perikaryon (ISO)

secretory granule (IEA,ISO)

Molecular Function

endopeptidase activity (IEA)

protein binding (ISO)

serine-type endopeptidase activity (IEA)

serine-type peptidase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

alfentanil pharmacodynamics pathway (ISO)

bupivacaine pharmacodynamics pathway (ISO)

buprenorphine pharmacodynamics pathway (ISO)

chloroprocaine pharmacodynamics pathway (ISO)

citalopram pharmacodynamics pathway (ISO)

cocaine pharmacodynamics pathway (ISO)

codeine and morphine pharmacodynamics pathway (ISO)

desipramine pharmacodynamics pathway (ISO)

diphenoxylate pharmacodynamics pathway (ISO)

escitalopram pharmacodynamics pathway (ISO)

ethylmorphine pharmacodynamics pathway (ISO)

fentanyl pharmacodynamics pathway (ISO)

fluoxetine pharmacodynamics pathway (ISO)

heroin pharmacodynamics pathway (ISO)

hydrocodone pharmacodynamics pathway (ISO)

hydromorphone pharmacodynamics pathway (ISO)

imipramine pharmacodynamics pathway (ISO)

levacetylmethadol pharmacodynamics pathway (ISO)

levobupivacaine phgarmacodynamics pathway (ISO)

levorphanol pharmacodynamics pathway (ISO)

lidocaine pharmacodynamics pathway (ISO)

melanocortin system pathway (ISO)

mepivacaine pharmacodynamics pathway (ISO)

methadone pharmacodynamics pathway (ISO)

nalbuphine pharmacodynamics pathway (ISO)

naloxone pharmacodynamics pathway (ISO)

naltrexone pharmacodynamics pathway (ISO)

nicotine pharmacodynamics pathway (ISO)

oxybuprocaine pharmacodynamics pathway (ISO)

oxycodone pharmacodynamics pathway (ISO)

oxymorphone pharmacodynamics pathway (ISO)

pentazocine pharmacodynamics pathway (ISO)

prilocaine pharmacodynamics pathway (ISO)

procaine pharmacodynamics pathway (ISO)

remifentanil pharmacodynamics pathway (ISO)

ropivacaine pharmacodynamics pathway (ISO)

tramadol pharmacodynamics pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Pcsk2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	154,177,620 - 154,434,915 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936485	2,608,353 - 2,866,294 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936485	2,611,313 - 2,866,260 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PCSK2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	17,226,107 - 17,484,578 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	17,226,107 - 17,484,578 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	20	17,206,752 - 17,465,223 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	17,155,631 - 17,413,223 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	20	17,155,630 - 17,413,223	NCBI
Celera	20	17,282,082 - 17,539,671 (+)	NCBI		Celera
Cytogenetic Map	20	p12.1	NCBI
HuRef	20	17,169,857 - 17,428,162 (+)	NCBI		HuRef
CHM1_1	20	17,206,780 - 17,465,251 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	17,276,847 - 17,535,278 (+)	NCBI		T2T-CHM13v2.0

Pcsk2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	143,388,053 - 143,658,204 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	143,388,076 - 143,658,205 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	143,546,133 - 143,816,284 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	143,546,156 - 143,816,285 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	143,371,869 - 143,642,020 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	143,237,620 - 143,507,725 (+)	NCBI		MGSCv36	mm8
Celera	2	144,735,342 - 144,999,086 (+)	NCBI		Celera
Cytogenetic Map	2	G1	NCBI
cM Map	2	70.89	NCBI

Pcsk2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	151,333,938 - 151,636,628 (+)	NCBI		GRCr8
mRatBN7.2	3	130,880,422 - 131,183,127 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	130,880,422 - 131,183,127 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	134,802,865 - 135,106,847 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	143,386,914 - 143,690,922 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	141,090,099 - 141,394,130 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	137,618,891 - 137,923,385 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	137,618,898 - 137,925,605 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	144,059,121 - 144,362,761 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	131,925,648 - 132,256,178 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	131,831,220 - 132,161,751 (+)	NCBI
Celera	3	129,792,699 - 130,080,973 (+)	NCBI		Celera
RH 3.4 Map	3	1176.7	RGD
Cytogenetic Map	3	q41	NCBI

Pcsk2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955415	26,266,484 - 26,497,001 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955415	26,266,513 - 26,496,905 (+)	NCBI	ChiLan1.0	ChiLan1.0

PCSK2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	18,114,726 - 18,371,018 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	18,111,564 - 18,367,856 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	17,184,878 - 17,443,355 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	17,163,675 - 17,421,157 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	17,163,675 - 17,421,157 (+)	Ensembl	panpan1.1		panPan2

PCSK2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	5,507,997 - 5,765,911 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	5,508,714 - 5,766,153 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	5,440,841 - 5,698,548 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	5,915,819 - 6,173,890 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	5,915,828 - 6,173,865 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	5,528,990 - 5,786,629 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	5,622,926 - 5,880,531 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	5,898,980 - 6,157,570 (-)	NCBI		UU_Cfam_GSD_1.0

PCSK2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	25,681,197 - 25,923,004 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	25,681,424 - 25,920,690 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	29,095,048 - 29,329,854 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PCSK2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	46,293,983 - 46,548,902 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	46,294,005 - 46,549,609 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666078	961,154 - 1,215,957 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pcsk2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624741	18,368,928 - 18,643,600 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624741	18,368,976 - 18,643,151 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013356426	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010003700	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000009907 ⟹ ENSSTOP00000008886

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936485	2,608,353 - 2,866,294 (-)	Ensembl

RefSeq Acc Id:

XM_013356426 ⟹ XP_013211880

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	154,177,620 - 154,434,915 (-)	NCBI
SpeTri2.0	NW_004936485	2,611,313 - 2,866,260 (-)	NCBI

Sequence:

show sequence

CCCAGTGGAACTGAAGCCGAGGAGGAGCTGAAAATGCAGATTTAGCATCAAGCACAGACATACA
CTCGCTCTTTCTCTCCGGTACACACAGCTCCCCACATTCGCACCCCTGCCAGCAAGCCGGGCCG
CTTGACTACACAGCCTCCCCGCCAGCCAGATGCTGGAGGAGAACACACACTGATTTGCTGCTTT
CCAAGCCCCAATTCAGTCTTTCTCCATACAAAGATTTTTTTAAACAACAACAAAAAACTACATA
TCTATTTTTTATTTGCACCTTCCCCTTCGGGTCCCCTGCTCCACCAGCCTGCGCTCCTTCTAAC
CCCACTTTTCACTCCCAAAGAAGGATGAAGGGTGGTTGTGGCTCCCAGTGGAAGGCAGCCGCTG
GGCTCCTCTTCTGTGTCATGGTTTTTGCATCTGCCGAGAAACCAGTCTTCACGAATCATTTTCT
TGTGGAGTTGCATAAAGGGGGAGAGGAAGAAGCTCGCCAAGTTGCAGCAGAACACGGCTTTGGA
GTCCGAAAGCTACCATTCGCAGAAGGCCTGTACCACTTTTATCACAATGGTCTTGCAAAGGCCA
AAAGAAGACGCAGCCTGCATCACAAGCAGCAGCTGGAGAGAGACCCCAGGGTAAAGATGGCCTT
GCAACAGGAAGGATTTGACCGAAAAAAGCGAGGATACAGAGACATCAACGATATTGACATCAAC
ATGAATGATCCTCTTTTTACAAAGCAGTGGTATCTGATCAACACTGGGCAAGCAGATGGTACAC
CAGGGCTTGATTTGAATGTGGCAGAAGCCTGGGAGCTGGGATACACTGGGAAAGGTGTGACCAT
TGGAATTATGGATGATGGAATTGACTACCTCCACCCAGACCTGGCCTCCAACTATAATGCCGAA
GCAAGTTACGACTTCAGCAGCAATGACCCCTATCCTTACCCTCGCTACACAGACGACTGGTTCA
ACAGCCACGGAACCCGATGTGCAGGAGAAGTCTCAGCAGCAGCCAACAACAATATTTGTGGGGT
TGGTGTAGCCTACAACTCCAAGGTTGCAGGTATACGGATGTTGGACCAGCCATTTATGACGGAC
ATCATCGAGGCCTCCTCCATCAGCCACATGCCACAGCTGATTGACATCTACAGCGCCAGCTGGG
GCCCCACAGACAATGGGAAGACGGTGGATGGACCCCGAGAACTCACGCTGCAGGCCATGGCGGA
TGGTGTGAACAAGGGTCGCGGGGGCAAAGGCAGCATCTACGTGTGGGCCTCTGGGGACGGCGGC
AGTTATGATGACTGCAATTGTGATGGCTACGCGTCAAGCATGTGGACCATCTCCATCAACTCGG
CCATCAATGACGGCAGGACAGCCCTGTACGACGAGAGCTGCTCCTCCACCTTGGCCTCCACCTT
CAGCAACGGCAGGAAGAGGAACCCTGAGGCCGGTGTGGCCACCACAGATTTGTATGGCAACTGC
ACACTGAGGCATTCTGGGACATCTGCAGCTGCTCCAGAAGCAGCTGGTGTGTTCGCCCTGGCTT
TAGAGGCTAACCTGGGCCTGACCTGGCGAGACATGCAGCATCTGACCGTGCTCACCTCCAAACG
GAACCAGCTTCACGACGAGGTCCATCAGTGGCGGCGAAACGGGGTCGGCCTGGAGTTTAATCAC
CTCTTTGGCTACGGGGTCCTTGATGCAGGCGCCATGGTGAAAATGGCTAAAGACTGGAAAACCG
TGCCTGAGAGATTCCACTGTGTGGGAGGCTCCGTGCAGGACCCTGAGAAAATACCATCCACTGG
CAAGCTGGTGCTGACCCTCACGACTGATGCATGTGAAGGGAAGGAGAATTTCGTCCGCTACCTC
GAGCACGTCCAAGCTGTCATCACAGTCAATGCAACCAGAAGAGGAGACCTGAACATCAACATGA
CTTCCCCTATGGGCACCAAGTCCATTTTGCTAAGCAGACGTCCAAGGGATGACGACTCCAAGGT
GGGCTTTGACAAGTGGCCTTTCATGACCACCCACACTTGGGGGGAAGATGCCCGAGGAACCTGG
ACCCTGGAGCTGGGGTTTGTGGGCAGCGCACCCCAGAAGGGGGTGCTAAAGGAGTGGACTCTCA
TGCTGCATGGCACACAGAGTGCCCCATACATCGACCAGGTGGTGAGGGATTACCAGTCCAAGCT
GGCCATGTCCAAAAAGCAAGAGCTAGAGGAAGAGCTGGACGAAGCTGTGGAGAGAAGCCTGAAA
AGCATCCTAAATAAGAACTAGTGCTGCACTTCTGCCTCCACCACCTCCTTCCCTTCCCATTCTC
TGCCTCTATCCTTGCTCCACATTTCTGGCAGGCACCTAGCAATTACTGTCACCCCACACAAGCA
ATTCCATCTTCTTGAACTGCAGCTTTGCTCACTATCAATGATTATTTTCATTACAATGAAAGCA
ACCTTTTTTTTTCTATGACCCAAATATAATGTTCCCACTAACA

hide sequence

Protein Sequences


Protein RefSeqs	XP_013211880	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000008886.3
GenBank Protein	KAG3262808	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_013211880 ⟸ XM_013356426

- UniProtKB:

I3MEG8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MKGGCGSQWKAAAGLLFCVMVFASAEKPVFTNHFLVELHKGGEEEARQVAAEHGFGVRKLPFAE
GLYHFYHNGLAKAKRRRSLHHKQQLERDPRVKMALQQEGFDRKKRGYRDINDIDINMNDPLFTK
QWYLINTGQADGTPGLDLNVAEAWELGYTGKGVTIGIMDDGIDYLHPDLASNYNAEASYDFSSN
DPYPYPRYTDDWFNSHGTRCAGEVSAAANNNICGVGVAYNSKVAGIRMLDQPFMTDIIEASSIS
HMPQLIDIYSASWGPTDNGKTVDGPRELTLQAMADGVNKGRGGKGSIYVWASGDGGSYDDCNCD
GYASSMWTISINSAINDGRTALYDESCSSTLASTFSNGRKRNPEAGVATTDLYGNCTLRHSGTS
AAAPEAAGVFALALEANLGLTWRDMQHLTVLTSKRNQLHDEVHQWRRNGVGLEFNHLFGYGVLD
AGAMVKMAKDWKTVPERFHCVGGSVQDPEKIPSTGKLVLTLTTDACEGKENFVRYLEHVQAVIT
VNATRRGDLNINMTSPMGTKSILLSRRPRDDDSKVGFDKWPFMTTHTWGEDARGTWTLELGFVG
SAPQKGVLKEWTLMLHGTQSAPYIDQVVRDYQSKLAMSKKQELEEELDEAVERSLKSILNKN

hide sequence

Ensembl Acc Id:

ENSSTOP00000008886 ⟸ ENSSTOT00000009907

Protein Domains

P/Homo B

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000009909	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000009907.3	UniProtKB/TrEMBL
Gene3D-CATH	3.30.70.850	UniProtKB/TrEMBL
	3.40.50.200	UniProtKB/TrEMBL
	Galactose-binding domain-like	UniProtKB/TrEMBL
InterPro	Galactose-bd-like_sf	UniProtKB/TrEMBL
	Kexin/furin	UniProtKB/TrEMBL
	P_dom	UniProtKB/TrEMBL
	Peptidase_S8/S53_dom	UniProtKB/TrEMBL
	Peptidase_S8/S53_dom_sf	UniProtKB/TrEMBL
	Peptidase_S8_Asp-AS	UniProtKB/TrEMBL
	Peptidase_S8_His-AS	UniProtKB/TrEMBL
	Peptidase_S8_Ser-AS	UniProtKB/TrEMBL
	Peptidase_S8_subtilisin-rel	UniProtKB/TrEMBL
	S8_pro-domain	UniProtKB/TrEMBL
	S8_pro-domain_sf	UniProtKB/TrEMBL
NCBI Gene	Pcsk2	ENTREZGENE
PANTHER	NEUROENDOCRINE CONVERTASE 2	UniProtKB/TrEMBL
	PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED	UniProtKB/TrEMBL
Pfam	P_proprotein	UniProtKB/TrEMBL
	Peptidase_S8	UniProtKB/TrEMBL
	S8_pro-domain	UniProtKB/TrEMBL
PRINTS	SUBTILISIN	UniProtKB/TrEMBL
PROSITE	P_HOMO_B	UniProtKB/TrEMBL
	SUBTILASE	UniProtKB/TrEMBL
	SUBTILASE_ASP	UniProtKB/TrEMBL
	SUBTILASE_HIS	UniProtKB/TrEMBL
	SUBTILASE_SER	UniProtKB/TrEMBL
Superfamily-SCOP	Protease propeptides/inhibitors	UniProtKB/TrEMBL
	SSF49785	UniProtKB/TrEMBL
	SSF52743	UniProtKB/TrEMBL
UniProt	I3MEG8	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - SMPDB

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - SMPDB