Kcnj2 (potassium inwardly rectifying channel subfamily J member 2) - Rat Genome Database

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Gene: Kcnj2 (potassium inwardly rectifying channel subfamily J member 2) Ictidomys tridecemlineatus
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Symbol: Kcnj2
Name: potassium inwardly rectifying channel subfamily J member 2
RGD ID: 12695208
Description: ENCODES a protein that exhibits identical protein binding (ortholog); inward rectifier potassium channel activity (ortholog); phosphatidylinositol-4,5-bisphosphate binding (ortholog); INVOLVED IN cardiac muscle cell action potential (ortholog); cardiac muscle cell action potential involved in contraction (ortholog); cellular response to mechanical stimulus (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH Andersen-Tawil syndrome (ortholog); Arsenic Poisoning (ortholog); atrial fibrillation (ortholog); FOUND IN dendrite (ortholog); dendritic spine (ortholog); Golgi apparatus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: inward rectifier potassium channel 2; potassium inwardly-rectifying channel, subfamily J, member 2; potassium voltage-gated channel subfamily J member 2; potassium voltage-gated channel subfamily J member 2, transcript variant X1; potassium voltage-gated channel subfamily J member 2, transcript variant X2; potassium voltage-gated channel subfamily J member 2, transcript variant X3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056029,949,176 - 9,968,112 (-)NCBI
SpeTri2.0NW_0049366553,447,026 - 3,459,569 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
acebutolol pharmacodynamics pathway  (ISO)
adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway  (ISO)
amiodarone pharmacodynamics pathway  (ISO)
amlodipine pharmacodynamics pathway  (ISO)
atenolol pharmacodynamics pathway  (ISO)
betaxolol pharmacodynamics pathway  (ISO)
bisoprolol pharmacodynamics pathway  (ISO)
bupranolol drug pathway  (ISO)
bupranolol pharmacodynamics pathway  (ISO)
carvedilol pharmacodynamics pathway  (ISO)
diltiazem pharmacodynamics pathway  (ISO)
disopyramide pharmacodynamics pathway  (ISO)
dobutamine pharmacodynamics pathway  (ISO)
esmolol pharmacodynamics pathway  (ISO)
flecainde pharmacodynamics pathway  (ISO)
fosphenytoin pharmacodynamics pathway  (ISO)
ibutilide pharmacodynamics pathway  (ISO)
isoprenaline pharmacodynamics pathway  (ISO)
isradipine pharmacodynamics pathway  (ISO)
levobunolol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
metoprolol pharmacodynamics pathway  (ISO)
mexiletine pharmacodynamics pathway  (ISO)
nadolol pharmacodynamics pathway  (ISO)
nebivolol pharmacodynamics pathway  (ISO)
neuron-to-neuron signaling pathway via the chemical synapse  (ISO)
nifedipine pharmacodynamics pathway  (ISO)
nimodipine pharmacodynamics pathway  (ISO)
nisoldipine pharmacodynamics pathway  (ISO)
nitrendipine pharmacodynamics pathway  (ISO)
penbutolol pharmacodynamics pathway  (ISO)
phenytoin pharmacodynamics pathway  (ISO)
pindolol pharmacodynamics pathway  (ISO)
procainamide pharmacodynamics pathway  (ISO)
propranolol pharmacodynamics pathway  (ISO)
quinidine pharmacodynamics pathway  (ISO)
sotalol pharmacodynamics pathway  (ISO)
timolol pharmacodynamics pathway  (ISO)
verapamil pharmacodynamics pathway  (ISO)

References

Genomics

Comparative Map Data
Kcnj2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056029,949,176 - 9,968,112 (-)NCBI
SpeTri2.0NW_0049366553,447,026 - 3,459,569 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNJ2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1770,168,673 - 70,180,044 (+)EnsemblGRCh38hg38GRCh38
GRCh381770,169,532 - 70,180,044 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371768,165,673 - 68,176,185 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361765,677,271 - 65,687,780 (+)NCBINCBI36hg18NCBI36
Build 341765,677,270 - 65,687,776NCBI
Celera1764,737,556 - 64,748,065 (+)NCBI
Cytogenetic Map17q24.3NCBI
HuRef1763,551,441 - 63,561,946 (+)NCBIHuRef
CHM1_11768,231,773 - 68,242,282 (+)NCBICHM1_1
Kcnj2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911110,956,990 - 110,967,651 (+)NCBIGRCm39mm39
GRCm39 Ensembl11110,956,990 - 110,967,647 (+)Ensembl
GRCm3811111,066,164 - 111,076,825 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11111,066,164 - 111,076,821 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711110,927,478 - 110,938,139 (+)NCBIGRCm37mm9NCBIm37
MGSCv3611110,882,254 - 110,891,741 (+)NCBImm8
Celera11122,816,654 - 122,827,315 (+)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1175.23NCBI
Kcnj2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21096,060,849 - 96,071,401 (+)NCBImRatBN7.2
Rnor_6.0 Ensembl1099,437,436 - 99,439,114 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01099,429,337 - 99,442,520 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01099,125,234 - 99,134,077 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410100,574,985 - 100,576,268 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.110100,589,354 - 100,590,638 (+)NCBI
Celera1094,712,069 - 94,713,352 (+)NCBICelera
Cytogenetic Map10q32.1NCBI
Kcnj2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554782,734,795 - 2,745,217 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554782,734,795 - 2,745,217 (-)NCBIChiLan1.0ChiLan1.0
KCNJ2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11769,482,344 - 69,492,838 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1769,487,846 - 69,489,129 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01764,097,908 - 64,112,914 (+)NCBIMhudiblu_PPA_v0panPan3
KCNJ2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1916,468,938 - 16,475,722 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl916,468,938 - 16,475,722 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha917,360,013 - 17,366,796 (+)NCBI
ROS_Cfam_1.0918,122,955 - 18,129,749 (+)NCBI
UMICH_Zoey_3.1917,067,115 - 17,073,888 (+)NCBI
UNSW_CanFamBas_1.0910,461,025 - 10,467,799 (-)NCBI
UU_Cfam_GSD_1.0910,426,806 - 10,433,589 (-)NCBI
KCNJ2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1210,349,409 - 10,362,244 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11210,351,959 - 10,380,631 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
KCNJ2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11651,448,821 - 51,461,801 (-)NCBI
ChlSab1.1 Ensembl1651,452,567 - 51,453,850 (-)Ensembl
Vero_WHO_p1.0NW_02366607722,340,093 - 22,354,971 (-)NCBI
Kcnj2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624801365,393 - 375,802 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005335988   ⟹   XP_005336045
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244056029,949,176 - 9,959,735 (-)NCBI
SpeTri2.0NW_0049366553,447,026 - 3,457,550 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005335989   ⟹   XP_005336046
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244056029,949,176 - 9,960,591 (-)NCBI
SpeTri2.0NW_0049366553,447,026 - 3,458,430 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021733728   ⟹   XP_021589403
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244056029,949,176 - 9,960,891 (-)NCBI
SpeTri2.0NW_0049366553,447,026 - 3,459,569 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040268518   ⟹   XP_040124452
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244056029,949,176 - 9,968,112 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_005336046   ⟸   XM_005335989
- UniProtKB: I3MQE3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005336045   ⟸   XM_005335988
- UniProtKB: I3MQE3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021589403   ⟸   XM_021733728
- Sequence:
RefSeq Acc Id: XP_040124452   ⟸   XM_040268518
Protein Domains
IRK   IRK_C   IRK_N


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000015811 ENTREZGENE
Ensembl Protein ENSSTOP00000014149 ENTREZGENE
NCBI Gene Kcnj2 ENTREZGENE
UniProt I3MQE3 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-07-23 Kcnj2  potassium inwardly rectifying channel subfamily J member 2  Kcnj2  potassium voltage-gated channel subfamily J member 2  Symbol and/or name change 5135510 APPROVED