Gmps (guanine monophosphate synthase) - Rat Genome Database

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Gene: Gmps (guanine monophosphate synthase) Ictidomys tridecemlineatus
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Symbol: Gmps
Name: guanine monophosphate synthase
RGD ID: 12695123
Description: ENCODES a protein that exhibits enzyme binding (ortholog); GMP synthase (glutamine-hydrolyzing) activity (ortholog); GMP synthase activity (ortholog); INVOLVED IN GMP biosynthetic process (ortholog); GMP salvage (ortholog); response to L-cysteine (ortholog); PARTICIPATES IN 2-hydroxyglutaric aciduria pathway; adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; ASSOCIATED WITH Acute Myelomonocytic Leukemia (ortholog); Experimental Diabetes Mellitus (ortholog); hepatocellular carcinoma (ortholog); FOUND IN cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: GMP synthase [glutamine-hydrolyzing]
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560286,587,606 - 86,639,212 (-)NCBI
SpeTri2.0NW_0049365193,094,763 - 3,143,322 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IEA,ISO)

Molecular Function

References

Genomics

Comparative Map Data
Gmps
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560286,587,606 - 86,639,212 (-)NCBI
SpeTri2.0NW_0049365193,094,763 - 3,143,322 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GMPS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383155,869,430 - 155,944,020 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl3155,870,650 - 155,944,020 (+)EnsemblGRCh38hg38GRCh38
GRCh373155,588,439 - 155,661,809 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363157,071,019 - 157,138,215 (+)NCBINCBI36hg18NCBI36
Build 343157,071,026 - 157,138,223NCBI
Celera3154,009,947 - 154,077,188 (+)NCBI
Cytogenetic Map3q25.31NCBI
HuRef3152,982,759 - 153,049,917 (+)NCBIHuRef
CHM1_13155,551,614 - 155,618,831 (+)NCBICHM1_1
T2T-CHM13v2.03158,645,288 - 158,718,668 (+)NCBI
Gmps
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39363,871,054 - 63,928,975 (+)NCBIGRCm39mm39
GRCm39 Ensembl363,883,527 - 63,930,000 (+)Ensembl
GRCm38363,963,633 - 64,021,554 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl363,976,106 - 64,022,579 (+)EnsemblGRCm38mm10GRCm38
MGSCv37363,780,065 - 63,823,000 (+)NCBIGRCm37mm9NCBIm37
MGSCv36364,064,072 - 64,107,007 (+)NCBImm8
Celera363,647,946 - 63,691,053 (+)NCBICelera
Cytogenetic Map3E1NCBI
Gmps
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22148,441,369 - 148,491,908 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl2148,435,643 - 148,485,875 (+)Ensembl
Rnor_6.02154,555,967 - 154,590,662 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2154,555,871 - 154,590,662 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02173,939,844 - 173,974,539 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42153,804,512 - 153,840,009 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12153,754,474 - 153,789,970 (+)NCBI
Celera2142,726,833 - 142,761,299 (+)NCBICelera
Cytogenetic Map2q31NCBI
Gmps
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554486,932,926 - 6,984,662 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554486,931,891 - 6,984,662 (+)NCBIChiLan1.0ChiLan1.0
GMPS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13160,977,222 - 161,045,214 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3160,977,222 - 161,045,214 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03152,925,905 - 152,999,180 (+)NCBIMhudiblu_PPA_v0panPan3
GMPS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12349,569,571 - 49,645,999 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2349,569,531 - 49,699,199 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2349,445,713 - 49,522,068 (+)NCBI
ROS_Cfam_1.02350,203,908 - 50,286,767 (+)NCBI
ROS_Cfam_1.0 Ensembl2350,203,868 - 50,333,624 (+)Ensembl
UMICH_Zoey_3.12349,789,609 - 49,866,167 (+)NCBI
UNSW_CanFamBas_1.02349,838,479 - 49,915,927 (+)NCBI
UU_Cfam_GSD_1.02350,126,162 - 50,202,992 (+)NCBI
GMPS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1395,742,383 - 95,819,762 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11395,742,342 - 95,820,903 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213103,766,547 - 103,819,693 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GMPS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11534,817,603 - 34,885,363 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1534,815,066 - 34,885,228 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660417,450,006 - 7,520,263 (-)NCBIVero_WHO_p1.0
Gmps
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473033,460,566 - 33,535,593 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462473033,459,059 - 33,535,593 (+)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_040269957   ⟹   XP_040125891
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560286,587,606 - 86,639,212 (-)NCBI
RefSeq Acc Id: XM_040269958   ⟹   XP_040125892
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560286,587,606 - 86,636,394 (-)NCBI
Protein Sequences
Protein RefSeqs XP_040125891 (Get FASTA)   NCBI Sequence Viewer  
  XP_040125892 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3270851 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_040125891   ⟸   XM_040269957
- Peptide Label: isoform X1
RefSeq Acc Id: XP_040125892   ⟸   XM_040269958
- Peptide Label: isoform X2
Protein Domains
GMPS ATP-PPase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000026541 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000021258 UniProtKB/TrEMBL
  ENSSTOP00000032136 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000020540 UniProtKB/TrEMBL
  ENSSTOT00000038403 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.620 UniProtKB/TrEMBL
  3.40.50.880 UniProtKB/TrEMBL
InterPro Class_I_gatase-like UniProtKB/TrEMBL
  GATASE UniProtKB/TrEMBL
  GMP_synth_C UniProtKB/TrEMBL
  GMP_synth_GATase UniProtKB/TrEMBL
  GMPS_ATP_PPase_dom UniProtKB/TrEMBL
  NAD/GMP_synthase UniProtKB/TrEMBL
  Rossmann-like_a/b/a_fold UniProtKB/TrEMBL
NCBI Gene Gmps ENTREZGENE
Pfam GATase UniProtKB/TrEMBL
  GMP_synt_C UniProtKB/TrEMBL
  NAD_synthase UniProtKB/TrEMBL
PROSITE GMPS_ATP_PPASE UniProtKB/TrEMBL
Superfamily-SCOP SSF52317 UniProtKB/TrEMBL
TIGRFAMs guaA_Nterm UniProtKB/TrEMBL
UniProt A0A287DEZ6_ICTTR UniProtKB/TrEMBL
  I3NA61_ICTTR UniProtKB/TrEMBL