Hif1a (hypoxia inducible factor 1 subunit alpha) - Rat Genome Database

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Gene: Hif1a (hypoxia inducible factor 1 subunit alpha) Ictidomys tridecemlineatus
Analyze
Symbol: Hif1a
Name: hypoxia inducible factor 1 subunit alpha
RGD ID: 12694245
Description: ENCODES a protein that exhibits DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); protein heterodimerization activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN acute-phase response (ortholog); angiogenesis (ortholog); apoptotic process (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; vascular endothelial growth factor signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); Acute-Phase Reaction (ortholog); Alcoholic Liver Diseases (ortholog); FOUND IN nucleus (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypoxia inducible factor 1 alpha subunit; hypoxia-inducible factor 1-alpha
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864068,375,541 - 68,420,766 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364955,770,669 - 5,816,157 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364955,770,988 - 5,816,157 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute kidney failure  (ISO)
Acute-Phase Reaction  (ISO)
Alcoholic Liver Diseases  (ISO)
Alzheimer's disease  (ISO)
Anaplasia  (ISO)
Arterial Thrombosis  (ISO)
Asphyxia  (ISO)
asthma  (ISO)
atrial fibrillation  (ISO)
bladder neck obstruction  (ISO)
Brain Hypoxia-Ischemia  (ISO)
brain infarction  (ISO)
brain ischemia  (ISO)
Breast Neoplasms  (ISO)
bronchopulmonary dysplasia  (ISO)
Burns  (ISO)
carcinoma  (ISO)
Cardiomegaly  (ISO)
cerebral infarction  (ISO)
cholangiocarcinoma  (ISO)
cholesteatoma of middle ear  (ISO)
Choroidal Neovascularization  (ISO)
Chronic Cerebral Hypoperfusion  (ISO)
Chronic Intermittent Hypoxia  (ISO)
chronic obstructive pulmonary disease  (ISO)
Colonic Neoplasms  (ISO)
colorectal cancer  (ISO)
congenital heart disease  (ISO)
congestive heart failure  (ISO)
decubitus ulcer  (ISO)
Diabetes Complications  (ISO)
Diabetic Foot  (ISO)
Diabetic Nephropathies  (ISO)
diabetic retinopathy  (ISO)
Disease Progression  (ISO)
Ductal Carcinoma  (ISO)
ductal carcinoma in situ  (ISO)
esophagus squamous cell carcinoma  (ISO)
Experimental Arthritis  (ISO)
Experimental Autoimmune Neuritis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Mammary Neoplasms  (ISO)
Experimental Neoplasms  (ISO)
Experimental Radiation Injuries  (ISO)
Femur Head Necrosis  (ISO)
genetic disease  (ISO)
glioblastoma  (ISO)
glycogen storage disease V  (ISO)
glycogen storage disease VII  (ISO)
Hearing Loss, Noise-Induced  (ISO)
hemangioblastoma  (ISO)
hepatic encephalopathy  (ISO)
hepatocellular carcinoma  (ISO)
Hot Flashes  (ISO)
Hyperalgesia  (ISO)
Hyperplasia  (ISO)
hypertension  (ISO)
idiopathic pulmonary fibrosis  (ISO)
Infarction  (ISO)
Intervertebral Disc Disease  (ISO)
invasive ductal carcinoma  (ISO)
kidney failure  (ISO)
Kidney Reperfusion Injury  (ISO)
limb ischemia  (ISO)
liver cirrhosis  (ISO)
lung disease  (ISO)
lung non-small cell carcinoma  (ISO)
macular retinal edema  (ISO)
Maffucci syndrome  (ISO)
malignant astrocytoma  (ISO)
Memory Disorders  (ISO)
Micronuclei, Chromosome-Defective  (ISO)
middle cerebral artery infarction  (ISO)
morbid obesity  (ISO)
mycosis fungoides  (ISO)
myocardial infarction  (ISO)
Myocardial Ischemia  (ISO)
Myocardial Reperfusion Injury  (ISO)
Neoplasm Invasiveness  (ISO)
Neoplastic Cell Transformation  (ISO)
nephroblastoma  (ISO)
obesity  (ISO)
olfactory neuroblastoma  (ISO)
Ollier disease  (ISO)
osteoarthritis  (ISO)
ovarian cancer  (ISO)
Oxygen-Induced Retinopathy  (ISO)
pancreatic cancer  (ISO)
Phyllodes Tumor  (ISO)
polycystic kidney disease  (ISO)
Postmenopausal Osteoporosis  (ISO)
pre-eclampsia  (ISO)
primary biliary cholangitis  (ISO)
prostate cancer  (ISO)
Prostatic Neoplasms  (ISO)
proteinuria  (ISO)
psoriasis  (ISO)
pulmonary hypertension  (ISO)
Radiation Injuries  (ISO)
renal cell carcinoma  (ISO)
Reperfusion Injury  (ISO)
retinal ischemia  (ISO)
Retinal Neovascularization  (ISO)
rheumatoid arthritis  (ISO)
sclerosing cholangitis  (ISO)
skin melanoma  (ISO)
Skin Neoplasms  (ISO)
Spinal Cord Injuries  (ISO)
Subarachnoid Hemorrhage  (ISO)
Temporomandibular Joint Disorders  (ISO)
Testis Reperfusion Injury  (ISO)
Thyroid Neoplasms  (ISO)
transient cerebral ischemia  (ISO)
type 2 diabetes mellitus  (ISO)
Ulcer  (ISO)
urinary bladder cancer  (ISO)
Urologic Neoplasms  (ISO)
varicocele  (ISO)
Venous Thrombosis  (ISO)
Ventricular Remodeling  (ISO)
Werner syndrome  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
acute-phase response  (ISO)
angiogenesis  (IEA,ISO)
apoptotic process  (IEA,ISO)
axonal transport of mitochondrion  (IEA)
B-1 B cell homeostasis  (IEA,ISO)
blood vessel development  (IEA,ISO)
blood vessel morphogenesis  (IEA,ISO)
bone mineralization  (IEA,ISO)
camera-type eye morphogenesis  (IEA,ISO)
cardiac ventricle morphogenesis  (IEA,ISO)
cartilage development  (IEA,ISO)
cell differentiation  (IEA,ISO)
cellular response to anoxia  (ISO)
cellular response to carbon monoxide  (ISO)
cellular response to cobalt ion  (ISO)
cellular response to cyanide  (ISO)
cellular response to electrical stimulus  (ISO)
cellular response to estrogen stimulus  (ISO)
cellular response to glucose stimulus  (ISO)
cellular response to hydrogen peroxide  (ISO)
cellular response to hypoxia  (IEA,ISO)
cellular response to insulin stimulus  (ISO)
cellular response to interleukin-1  (IEA,ISO)
cellular response to light stimulus  (ISO)
cellular response to lipid  (ISO)
cellular response to lipopolysaccharide  (ISO)
cellular response to mechanical stimulus  (ISO)
cellular response to nitrite  (ISO)
cellular response to organic cyclic compound  (ISO)
cellular response to oxidative stress  (IEA)
cellular response to toxic substance  (ISO)
cellular response to virus  (IEA)
cellular response to wortmannin  (ISO)
cellular response to xenobiotic stimulus  (ISO)
cerebral cortex development  (IEA,ISO)
chondrocyte differentiation  (IEA,ISO)
collagen metabolic process  (IEA)
connective tissue replacement involved in inflammatory response wound healing  (IEA)
digestive tract morphogenesis  (IEA,ISO)
dopaminergic neuron differentiation  (IEA,ISO)
elastin metabolic process  (IEA)
embryonic hemopoiesis  (IEA,ISO)
embryonic placenta development  (IEA,ISO)
epithelial cell differentiation involved in mammary gland alveolus development  (IEA,ISO)
epithelial to mesenchymal transition  (IEA)
glandular epithelial cell differentiation  (IEA,ISO)
glandular epithelial cell maturation  (IEA,ISO)
glucose homeostasis  (IEA,ISO)
heart looping  (IEA,ISO)
hemoglobin biosynthetic process  (IEA,ISO)
hypoxia-inducible factor-1alpha signaling pathway  (IEA,ISO)
insulin secretion involved in cellular response to glucose stimulus  (IEA,ISO)
intestinal epithelial cell maturation  (IEA,ISO)
intracellular glucose homeostasis  (IEA)
intracellular iron ion homeostasis  (IEA,ISO)
intracellular oxygen homeostasis  (IEA,ISO)
iris morphogenesis  (IEA,ISO)
iron import into the mitochondrion  (ISO)
lactate metabolic process  (IEA,ISO)
lactation  (IEA,ISO)
maternal process involved in female pregnancy  (ISO)
mesenchymal cell apoptotic process  (IEA,ISO)
muscle cell cellular homeostasis  (IEA,ISO)
negative regulation of apoptotic process  (IEA,ISO)
negative regulation of bone mineralization  (IEA,ISO)
negative regulation of gene expression  (IEA)
negative regulation of growth  (IEA,ISO)
negative regulation of mesenchymal cell apoptotic process  (IEA,ISO)
negative regulation of miRNA transcription  (IEA)
negative regulation of neuron apoptotic process  (IEA,ISO)
negative regulation of ossification  (IEA)
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway  (IEA)
negative regulation of reactive oxygen species biosynthetic process  (ISO)
negative regulation of reactive oxygen species metabolic process  (IEA)
negative regulation of thymocyte apoptotic process  (IEA,ISO)
negative regulation of TOR signaling  (IEA,ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
negative regulation of vasoconstriction  (ISO)
neural crest cell migration  (IEA,ISO)
neural fold elevation formation  (IEA,ISO)
neuroblast proliferation  (IEA,ISO)
neuron apoptotic process  (IEA,ISO)
outflow tract morphogenesis  (IEA,ISO)
positive regulation of angiogenesis  (IEA)
positive regulation of apoptotic process  (ISO)
positive regulation of autophagy  (IEA)
positive regulation of blood vessel endothelial cell migration  (IEA)
positive regulation of cell population proliferation  (ISO)
positive regulation of cell size  (ISO)
positive regulation of chemokine-mediated signaling pathway  (IEA,ISO)
positive regulation of cytokine production involved in inflammatory response  (IEA)
positive regulation of DNA-templated transcription  (IEA,ISS)
positive regulation of endothelial cell migration  (ISO)
positive regulation of epithelial cell migration  (IEA)
positive regulation of erythrocyte differentiation  (IEA,ISO)
positive regulation of gene expression  (IEA,ISO)
positive regulation of gluconeogenesis  (ISO)
positive regulation of hormone biosynthetic process  (IEA)
positive regulation of insulin secretion involved in cellular response to glucose stimulus  (IEA,ISO)
positive regulation of macroautophagy  (IEA,ISO)
positive regulation of miRNA transcription  (IEA)
positive regulation of mitophagy  (IEA)
positive regulation of neuroblast proliferation  (IEA,ISO)
positive regulation of smooth muscle cell proliferation  (ISO)
positive regulation of sprouting angiogenesis  (ISO)
positive regulation of stress granule assembly  (ISO)
positive regulation of transcription by RNA polymerase II  (IEA,ISO)
positive regulation of vascular endothelial growth factor production  (IEA,ISO)
positive regulation of vascular endothelial growth factor receptor signaling pathway  (IEA,ISO)
positive regulation of vascular wound healing  (ISO)
regulation of aerobic respiration  (IEA)
regulation of cell population proliferation  (IEA,ISO)
regulation of cellular response to hypoxia  (ISO)
regulation of DNA-templated transcription  (IEA,ISO)
regulation of gene expression  (IEA)
regulation of glycolytic process  (IEA,ISO)
regulation of protein neddylation  (IEA)
regulation of thymocyte apoptotic process  (IEA,ISO)
regulation of transcription by RNA polymerase II  (IEA,ISO)
regulation of transforming growth factor beta2 production  (IEA)
response to activity  (ISO)
response to alkaloid  (ISO)
response to anesthetic  (ISO)
response to auditory stimulus  (ISO)
response to cobalt ion  (ISO)
response to estradiol  (ISO)
response to estrogen  (ISO)
response to fungicide  (ISO)
response to glucocorticoid  (ISO)
response to glucose  (ISO)
response to hypoxia  (IEA,ISO,ISS)
response to iron ion  (IEA)
response to mechanical stimulus  (ISO)
response to muscle activity  (IEA,ISO)
response to purine-containing compound  (ISO)
response to reactive oxygen species  (IEA)
response to salt stress  (ISO)
response to X-ray  (ISO)
response to xenobiotic stimulus  (ISO)
retina vasculature development in camera-type eye  (IEA,ISO)
signal transduction  (IEA)
tissue remodeling  (ISO)
TOR signaling  (IEA,ISO)
vascular endothelial growth factor production  (IEA)
vasculature development  (IEA,ISO)
visual learning  (IEA,ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:15811624   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Hif1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864068,375,541 - 68,420,766 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364955,770,669 - 5,816,157 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364955,770,988 - 5,816,157 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HIF1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381461,695,513 - 61,748,258 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1461,695,513 - 61,748,259 (+)EnsemblGRCh38hg38GRCh38
GRCh371462,162,231 - 62,214,976 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361461,231,992 - 61,284,729 (+)NCBINCBI36Build 36hg18NCBI36
Build 341461,231,991 - 61,284,729NCBI
Celera1442,212,391 - 42,265,247 (+)NCBICelera
Cytogenetic Map14q23.2NCBI
HuRef1442,326,005 - 42,378,869 (+)NCBIHuRef
CHM1_11462,101,569 - 62,154,420 (+)NCBICHM1_1
T2T-CHM13v2.01455,902,080 - 55,954,826 (+)NCBIT2T-CHM13v2.0
Hif1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391273,948,186 - 73,994,304 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1273,948,149 - 73,994,304 (+)EnsemblGRCm39 Ensembl
GRCm381273,901,324 - 73,947,554 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1273,901,375 - 73,947,530 (+)EnsemblGRCm38mm10GRCm38
MGSCv371275,008,854 - 75,048,517 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361274,826,868 - 74,865,729 (+)NCBIMGSCv36mm8
Celera1275,021,612 - 75,061,060 (+)NCBICelera
Cytogenetic Map12C3NCBI
cM Map1231.99NCBI
Hif1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8698,357,788 - 98,405,068 (+)NCBIGRCr8
mRatBN7.2692,624,059 - 92,669,262 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl692,624,390 - 92,669,261 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx693,016,163 - 93,061,234 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0693,315,666 - 93,360,736 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0692,743,543 - 92,788,613 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0696,810,868 - 96,856,303 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl696,810,907 - 96,856,052 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06106,242,409 - 106,287,957 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4696,419,024 - 96,463,891 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1696,422,479 - 96,467,347 (+)NCBI
Celera691,083,300 - 91,128,125 (+)NCBICelera
Cytogenetic Map6q24NCBI
Hif1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554668,000,044 - 8,022,497 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554668,000,311 - 8,022,497 (-)NCBIChiLan1.0ChiLan1.0
HIF1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21562,825,050 - 62,878,472 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11462,041,761 - 62,094,986 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01442,295,691 - 42,348,478 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11460,552,374 - 60,604,885 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1460,552,374 - 60,604,885 (+)Ensemblpanpan1.1panPan2
HIF1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1836,614,045 - 36,656,692 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl836,614,045 - 36,656,692 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha836,366,891 - 36,409,562 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0836,847,226 - 36,889,848 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl836,847,066 - 36,889,846 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1836,456,745 - 36,499,380 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0836,534,215 - 36,576,862 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0836,896,640 - 36,939,279 (+)NCBIUU_Cfam_GSD_1.0
HIF1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1190,625,244 - 190,674,845 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11190,625,436 - 190,673,926 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21212,130,958 - 212,179,888 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HIF1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12438,873,830 - 38,927,657 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2438,873,861 - 38,928,288 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605327,124,225 - 27,177,215 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hif1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473439,411,824 - 39,471,705 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473439,414,458 - 39,471,705 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000004839   ⟹   ENSSTOP00000004344
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364955,770,669 - 5,816,157 (+)Ensembl
RefSeq Acc Id: NM_001282252   ⟹   NP_001269181
RefSeq Status: VALIDATED
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864068,376,742 - 68,420,424 (-)NCBI
SpeTri2.0NW_0049364955,771,275 - 5,814,957 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013357468   ⟹   XP_013212922
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864068,375,541 - 68,420,766 (-)NCBI
SpeTri2.0NW_0049364955,770,988 - 5,816,157 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001269181 (Get FASTA)   NCBI Sequence Viewer  
  XP_013212922 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAU14021 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000004344.2
Reference Protein Sequences
RefSeq Acc Id: XP_013212922   ⟸   XM_013357468
- Peptide Label: isoform X1
- UniProtKB: I3M4Y9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001269181   ⟸   NM_001282252
- UniProtKB: Q64F54 (UniProtKB/TrEMBL),   I3M4Y9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000004344   ⟸   ENSSTOT00000004839
Protein Domains
bHLH   PAS


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000004833 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000004839.3 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/TrEMBL
  PAS domain UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/TrEMBL
  HIF-1_alpha UniProtKB/TrEMBL
  HIF-1_TAD_C UniProtKB/TrEMBL
  HIF_alpha_subunit UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/TrEMBL
  PAC UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
  PAS-like_dom_sf UniProtKB/TrEMBL
  PAS_fold UniProtKB/TrEMBL
  PAS_fold_3 UniProtKB/TrEMBL
NCBI Gene Hif1a ENTREZGENE
PANTHER HYPOXIA-INDUCIBLE FACTOR 1 ALPHA UniProtKB/TrEMBL
  HYPOXIA-INDUCIBLE FACTOR 1-ALPHA UniProtKB/TrEMBL
Pfam HIF-1 UniProtKB/TrEMBL
  HIF-1a_CTAD UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
  PAS_3 UniProtKB/TrEMBL
PRINTS HYPOXIAIF1A UniProtKB/TrEMBL
PROSITE BHLH UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
SMART HLH UniProtKB/TrEMBL
  PAC UniProtKB/TrEMBL
  PAS UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/TrEMBL
  SSF55785 UniProtKB/TrEMBL
UniProt I3M4Y9 ENTREZGENE, UniProtKB/TrEMBL
  Q64F54 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-01 Hif1a  hypoxia inducible factor 1 subunit alpha    hypoxia inducible factor 1 alpha subunit  Symbol and/or name change 5135510 APPROVED