Dab2 (DAB adaptor protein 2) - Rat Genome Database

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Gene: Dab2 (DAB adaptor protein 2) Ictidomys tridecemlineatus
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Symbol: Dab2
Name: DAB adaptor protein 2
RGD ID: 12693925
Description: ENCODES a protein that exhibits low-density lipoprotein particle receptor binding (ortholog); INVOLVED IN cellular response to epidermal growth factor stimulus (ortholog); cellular response to transforming growth factor beta stimulus (ortholog); clathrin coat assembly (ortholog); PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH Brain Injuries (ortholog); Experimental Autoimmune Encephalomyelitis (ortholog); metabolic acidosis (ortholog); FOUND IN clathrin-coated vesicle membrane (ortholog); perinuclear region of cytoplasm (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: disabled homolog 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213228,434,139 - 228,472,266 (-)NCBI
SpeTri2.0NW_0049365182,915,819 - 2,936,474 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Dab2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213228,434,139 - 228,472,266 (-)NCBI
SpeTri2.0NW_0049365182,915,819 - 2,936,474 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DAB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl539,371,675 - 39,462,300 (-)EnsemblGRCh38hg38GRCh38
GRCh38539,460,870 - 39,462,304 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37539,371,776 - 39,425,335 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36539,407,537 - 39,461,092 (-)NCBINCBI36hg18NCBI36
Build 34539,408,502 - 39,460,703NCBI
Celera539,258,704 - 39,312,863 (-)NCBI
Cytogenetic Map5p13.1NCBI
HuRef539,323,383 - 39,377,010 (-)NCBIHuRef
CHM1_1539,373,679 - 39,427,330 (-)NCBICHM1_1
Dab2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2255,514,692 - 55,567,476 (+)NCBI
Rnor_6.0 Ensembl255,747,318 - 55,768,270 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0255,747,353 - 55,768,848 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0275,489,435 - 75,510,930 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4255,714,874 - 55,736,370 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1255,643,109 - 55,664,600 (+)NCBI
Celera251,166,390 - 51,187,877 (+)NCBICelera
Cytogenetic Map2q16NCBI
Dab2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542623,852,752 - 23,883,030 (-)NCBIChiLan1.0ChiLan1.0
DAB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1575,954,815 - 76,044,789 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl576,022,143 - 76,041,443 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0570,951,198 - 71,004,836 (+)NCBIMhudiblu_PPA_v0panPan3
DAB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1624,514,722 - 24,776,903 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11624,590,638 - 24,776,937 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21625,732,883 - 25,757,751 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DAB2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1438,171,320 - 38,224,275 (-)NCBI
ChlSab1.1 Ensembl438,173,026 - 38,224,231 (-)Ensembl
Vero_WHO_p1.0NW_02366607128,550,756 - 28,603,647 (-)NCBI
Dab2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475915,459,436 - 15,520,225 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_013358776   ⟹   XP_013214230
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213228,434,139 - 228,458,449 (-)NCBI
SpeTri2.0NW_0049365182,915,819 - 2,936,474 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013358777   ⟹   XP_013214231
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213228,434,139 - 228,458,449 (-)NCBI
SpeTri2.0NW_0049365182,915,819 - 2,936,474 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013358778   ⟹   XP_013214232
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213228,434,139 - 228,458,450 (-)NCBI
SpeTri2.0NW_0049365182,915,819 - 2,936,474 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013358779   ⟹   XP_013214233
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213228,434,139 - 228,458,449 (-)NCBI
SpeTri2.0NW_0049365182,915,819 - 2,936,474 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040272383   ⟹   XP_040128317
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213228,434,139 - 228,472,266 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_013214230   ⟸   XM_013358776
- Peptide Label: isoform X1
- UniProtKB: A0A287DCU6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013214232   ⟸   XM_013358778
- Peptide Label: isoform X4
- UniProtKB: I3M0H0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013214231   ⟸   XM_013358777
- Peptide Label: isoform X2
- UniProtKB: A0A287CY02 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013214233   ⟸   XM_013358779
- Peptide Label: isoform X5
- UniProtKB: A0A287CT74 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040128317   ⟸   XM_040272383
- Peptide Label: isoform X3
Protein Domains
PID


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000002461 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000002204 ENTREZGENE, UniProtKB/TrEMBL
  ENSSTOP00000024468 ENTREZGENE, UniProtKB/TrEMBL
  ENSSTOP00000026210 ENTREZGENE, UniProtKB/TrEMBL
  ENSSTOP00000031387 ENTREZGENE, UniProtKB/TrEMBL
  ENSSTOP00000032340 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000002465 UniProtKB/TrEMBL
  ENSSTOT00000033394 UniProtKB/TrEMBL
  ENSSTOT00000037377 UniProtKB/TrEMBL
  ENSSTOT00000038558 UniProtKB/TrEMBL
  ENSSTOT00000040967 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
InterPro PH_dom-like UniProtKB/TrEMBL
  PTB/PI_dom UniProtKB/TrEMBL
NCBI Gene Dab2 ENTREZGENE
Pfam PID UniProtKB/TrEMBL
PROSITE PID UniProtKB/TrEMBL
SMART PTB UniProtKB/TrEMBL
UniProt A0A287CT74 ENTREZGENE, UniProtKB/TrEMBL
  A0A287CY02 ENTREZGENE, UniProtKB/TrEMBL
  A0A287DCU6 ENTREZGENE, UniProtKB/TrEMBL
  A0A287DFN2_ICTTR UniProtKB/TrEMBL
  I3M0H0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-02-05 Dab2  DAB adaptor protein 2    DAB2, clathrin adaptor protein  Symbol and/or name change 5135510 APPROVED