Itgb2 (integrin subunit beta 2) - Rat Genome Database

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Gene: Itgb2 (integrin subunit beta 2) Ictidomys tridecemlineatus
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Symbol: Itgb2
Name: integrin subunit beta 2
RGD ID: 12691416
Description: ENCODES a protein that exhibits amyloid-beta binding (ortholog); cargo receptor activity (ortholog); cell adhesion molecule binding (ortholog); INVOLVED IN activated T cell proliferation (ortholog); aging (ortholog); amyloid-beta clearance (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; integrin mediated signaling pathway; ASSOCIATED WITH Acute Lung Injury (ortholog); acute promyelocytic leukemia (ortholog); allergic disease (ortholog); FOUND IN cell surface (ortholog); cytoplasmic region (ortholog); external side of plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: integrin beta-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497137,819,024 - 37,843,866 (-)NCBI
SpeTri2.0NW_0049367781,286,475 - 1,311,184 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Itgb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497137,819,024 - 37,843,866 (-)NCBI
SpeTri2.0NW_0049367781,286,475 - 1,311,184 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ITGB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2144,885,953 - 44,931,989 (-)EnsemblGRCh38hg38GRCh38
GRCh382144,885,949 - 44,928,815 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372146,305,868 - 46,348,730 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362145,130,296 - 45,165,303 (-)NCBINCBI36hg18NCBI36
Build 342145,130,313 - 45,165,232NCBI
Celera2131,412,498 - 31,455,256 (-)NCBI
Cytogenetic Map21q22.3NCBI
HuRef2131,679,225 - 31,721,357 (-)NCBIHuRef
CHM1_12145,866,651 - 45,909,384 (-)NCBICHM1_1
Itgb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391077,366,164 - 77,401,542 (+)NCBIGRCm39mm39
GRCm39 Ensembl1077,366,086 - 77,401,542 (+)Ensembl
GRCm381077,530,329 - 77,565,708 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1077,530,252 - 77,565,708 (+)EnsemblGRCm38mm10GRCm38
MGSCv371076,993,093 - 77,028,419 (+)NCBIGRCm37mm9NCBIm37
MGSCv361076,985,685 - 77,009,099 (+)NCBImm8
Celera1078,572,639 - 78,608,564 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Itgb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22011,061,394 - 11,097,656 (-)NCBI
Rnor_6.0 Ensembl2011,777,783 - 11,815,647 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.02011,777,773 - 11,815,647 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02013,944,190 - 13,981,048 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42011,446,521 - 11,485,009 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12011,446,936 - 11,485,236 (-)NCBI
Celera2012,564,941 - 12,601,097 (-)NCBICelera
Cytogenetic Map20p12NCBI
Itgb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540741,777,777 - 41,800,201 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540741,779,849 - 41,805,637 (-)NCBIChiLan1.0ChiLan1.0
ITGB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12144,470,999 - 44,505,963 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2144,470,999 - 44,505,963 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02131,181,228 - 31,216,033 (-)NCBIMhudiblu_PPA_v0panPan3
ITGB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13138,520,733 - 38,547,003 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3138,521,103 - 38,547,018 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3137,718,851 - 37,741,911 (-)NCBI
ROS_Cfam_1.03138,125,566 - 38,152,274 (-)NCBI
UMICH_Zoey_3.13137,988,075 - 38,014,617 (-)NCBI
UNSW_CanFamBas_1.03137,949,217 - 37,972,818 (-)NCBI
UU_Cfam_GSD_1.03138,463,168 - 38,490,402 (-)NCBI
ITGB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13207,512,954 - 207,544,108 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113207,514,281 - 207,544,108 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213217,446,055 - 217,475,887 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ITGB2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1288,597,554 - 88,644,890 (-)NCBI
ChlSab1.1 Ensembl288,597,556 - 88,624,025 (-)Ensembl
Itgb2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474530,452,576 - 30,479,036 (-)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_021720072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_021720072   ⟹   XP_021575747
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440497137,819,024 - 37,843,866 (-)NCBI
SpeTri2.0NW_0049367781,286,475 - 1,311,184 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_021575747 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_021575747   ⟸   XM_021720072
- Sequence:
Protein Domains
EGF-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000001412 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000001265 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000001411 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.410 UniProtKB/TrEMBL
InterPro EGF-like_dom UniProtKB/TrEMBL
  Integrin_beta_N UniProtKB/TrEMBL
  Integrin_bsu UniProtKB/TrEMBL
  Integrin_bsu-2 UniProtKB/TrEMBL
  Integrin_bsu_cyt_dom UniProtKB/TrEMBL
  Integrin_bsu_tail UniProtKB/TrEMBL
  Integrin_bsu_tail_dom_sf UniProtKB/TrEMBL
  Integrin_bsu_VWA UniProtKB/TrEMBL
  Integrin_dom_sf UniProtKB/TrEMBL
  PSI UniProtKB/TrEMBL
  vWFA_dom_sf UniProtKB/TrEMBL
NCBI Gene Itgb2 ENTREZGENE
PANTHER PTHR10082 UniProtKB/TrEMBL
  PTHR10082:SF15 UniProtKB/TrEMBL
Pfam Integrin_b_cyt UniProtKB/TrEMBL
  Integrin_B_tail UniProtKB/TrEMBL
  Integrin_beta UniProtKB/TrEMBL
  PSI_integrin UniProtKB/TrEMBL
PIRSF Integrin_B UniProtKB/TrEMBL
PRINTS INTEGRINB UniProtKB/TrEMBL
PROSITE EGF_1 UniProtKB/TrEMBL
  INTEGRIN_BETA UniProtKB/TrEMBL
SMART INB UniProtKB/TrEMBL
  Integrin_b_cyt UniProtKB/TrEMBL
  Integrin_B_tail UniProtKB/TrEMBL
  PSI UniProtKB/TrEMBL
Superfamily-SCOP SSF53300 UniProtKB/TrEMBL
  SSF69179 UniProtKB/TrEMBL
  SSF69687 UniProtKB/TrEMBL
UniProt I3LYJ1_ICTTR UniProtKB/TrEMBL