Def8 (differentially expressed in FDCP 8 homolog) - Rat Genome Database

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Gene: Def8 (differentially expressed in FDCP 8 homolog) Ictidomys tridecemlineatus
Analyze
Symbol: Def8
Name: differentially expressed in FDCP 8 homolog
RGD ID: 12691187
Description: INVOLVED IN lysosome localization (inferred); positive regulation of bone resorption (inferred); positive regulation of ruffle assembly (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934924,404,568 - 24,420,958 (-)NCBI
SpeTri2.0NW_004936641158,115 - 174,524 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

Genomics

Comparative Map Data
Def8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934924,404,568 - 24,420,958 (-)NCBI
SpeTri2.0NW_004936641158,115 - 174,524 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DEF8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381689,948,755 - 89,968,060 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1689,948,697 - 89,968,060 (+)EnsemblGRCh38hg38GRCh38
GRCh371690,015,163 - 90,034,468 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361688,542,652 - 88,561,968 (+)NCBINCBI36hg18NCBI36
Celera1675,080,190 - 75,100,010 (+)NCBI
Cytogenetic Map16q24.3NCBI
HuRef1675,708,713 - 75,727,359 (+)NCBIHuRef
CHM1_11691,427,253 - 91,446,352 (+)NCBICHM1_1
Def8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398124,169,695 - 124,193,275 (+)NCBIGRCm39mm39
GRCm39 Ensembl8124,150,266 - 124,190,009 (+)Ensembl
GRCm388123,442,956 - 123,467,076 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8123,423,527 - 123,463,270 (+)EnsemblGRCm38mm10GRCm38
MGSCv378125,966,886 - 125,987,799 (+)NCBIGRCm37mm9NCBIm37
MGSCv368126,329,076 - 126,349,989 (+)NCBImm8
Celera8127,679,290 - 127,701,748 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map872.1NCBI
Def8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21951,474,783 - 51,495,638 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1951,474,878 - 51,495,638 (+)Ensembl
Rnor_6.01956,238,353 - 56,259,867 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1956,243,408 - 56,259,196 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01966,949,601 - 66,969,857 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41953,765,017 - 53,781,294 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11953,769,897 - 53,786,171 (+)NCBI
Celera1950,712,066 - 50,727,943 (+)NCBICelera
Cytogenetic Map19q12NCBI
Def8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555413,412,484 - 3,424,869 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555413,412,534 - 3,424,010 (+)NCBIChiLan1.0ChiLan1.0
DEF8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11690,375,667 - 90,394,225 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1690,375,667 - 90,394,225 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01670,710,131 - 70,730,332 (+)NCBIMhudiblu_PPA_v0panPan3
DEF8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1563,656,411 - 63,671,934 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl563,656,218 - 63,669,025 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha563,669,605 - 63,685,136 (-)NCBI
ROS_Cfam_1.0563,884,458 - 63,900,204 (-)NCBI
ROS_Cfam_1.0 Ensembl563,877,522 - 63,900,172 (-)Ensembl
UMICH_Zoey_3.1563,904,916 - 63,920,446 (-)NCBI
UNSW_CanFamBas_1.0563,736,645 - 63,758,180 (-)NCBI
UU_Cfam_GSD_1.0564,148,799 - 64,164,331 (-)NCBI
DEF8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6140,897 - 160,884 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16140,854 - 160,936 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26293,386 - 307,179 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DEF8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1575,274,379 - 75,294,458 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl575,275,190 - 75,295,178 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666047123,902 - 145,056 (-)NCBIVero_WHO_p1.0
Def8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474699,543 - 119,535 (-)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005335405   ⟹   XP_005335462
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934924,404,568 - 24,420,957 (-)NCBI
SpeTri2.0NW_004936641158,115 - 174,524 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013362932   ⟹   XP_013218386
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934924,404,568 - 24,420,957 (-)NCBI
SpeTri2.0NW_004936641158,115 - 174,524 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013362933   ⟹   XP_013218387
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934924,404,568 - 24,420,957 (-)NCBI
SpeTri2.0NW_004936641158,115 - 174,524 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013362937   ⟹   XP_013218391
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934924,404,568 - 24,420,957 (-)NCBI
SpeTri2.0NW_004936641158,115 - 174,524 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021733347   ⟹   XP_021589022
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934924,404,568 - 24,420,553 (-)NCBI
SpeTri2.0NW_004936641158,115 - 174,099 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040279076   ⟹   XP_040135010
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934924,404,568 - 24,420,958 (-)NCBI
RefSeq Acc Id: XM_040279077   ⟹   XP_040135011
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934924,404,568 - 24,420,957 (-)NCBI
RefSeq Acc Id: XM_040279078   ⟹   XP_040135012
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934924,404,568 - 24,420,553 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_013218386   ⟸   XM_013362932
- Peptide Label: isoform X2
- UniProtKB: A0A287D4E4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013218387   ⟸   XM_013362933
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_005335462   ⟸   XM_005335405
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013218391   ⟸   XM_013362937
- Peptide Label: isoform X5
- UniProtKB: A0A287DFX1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021589022   ⟸   XM_021733347
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_040135010   ⟸   XM_040279076
- Peptide Label: isoform X4
RefSeq Acc Id: XP_040135011   ⟸   XM_040279077
- Peptide Label: isoform X5
RefSeq Acc Id: XP_040135012   ⟸   XM_040279078
- Peptide Label: isoform X5
Protein Domains
Phorbol-ester/DAG-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000020573 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000021656 UniProtKB/TrEMBL
  ENSSTOP00000028385 ENTREZGENE, UniProtKB/TrEMBL
  ENSSTOP00000032448 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000023781 UniProtKB/TrEMBL
  ENSSTOT00000038592 UniProtKB/TrEMBL
  ENSSTOT00000043234 UniProtKB/TrEMBL
InterPro Multihaem_cyt_sf UniProtKB/TrEMBL
  PE/DAG-bd UniProtKB/TrEMBL
  Zf-RING_9 UniProtKB/TrEMBL
NCBI Gene Def8 ENTREZGENE
Pfam C1_1 UniProtKB/TrEMBL
  zf-RING_9 UniProtKB/TrEMBL
PROSITE ZF_DAG_PE_1 UniProtKB/TrEMBL
  ZF_DAG_PE_2 UniProtKB/TrEMBL
SMART DUF4206 UniProtKB/TrEMBL
  SM00109 UniProtKB/TrEMBL
Superfamily-SCOP SSF48695 UniProtKB/TrEMBL
UniProt A0A287D4E4 ENTREZGENE, UniProtKB/TrEMBL
  A0A287DFX1 ENTREZGENE, UniProtKB/TrEMBL
  I3NBA9_ICTTR UniProtKB/TrEMBL