Parpbp (PARP1 binding protein) - Rat Genome Database

Name: Parpbp
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Parpbp (PARP1 binding protein) Ictidomys tridecemlineatus

Analyze

Symbol:

Parpbp

Name:

PARP1 binding protein

RGD ID:

12690399

Description:

INVOLVED IN negative regulation of double-strand break repair via homologous recombination (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN chromatin (inferred); cytoplasm (inferred); nucleoplasm (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

LOC101969566; PCNA-interacting partner

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PARPBP (PARP1 binding protein)	NCBI	Ortholog
Mus musculus (house mouse):	Parpbp (PARP1 binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Parpbp (PARP1 binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Parpbp (PARP1 binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PARPBP (PARP1 binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PARPBP (PARP1 binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PARPBP (PARP1 binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PARPBP (PARP1 binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Parpbp (PARP1 binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	18,938,566 - 18,988,550 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936492	11,948,765 - 11,994,838 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936492	11,948,765 - 11,994,838 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of double-strand break repair via homologous recombination (IEA)

Cellular Component

chromatin (IEA)

cytoplasm (IEA)

nucleoplasm (IEA)

nucleus (IEA)

Molecular Function

protein binding (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Parpbp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	18,938,566 - 18,988,550 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936492	11,948,765 - 11,994,838 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936492	11,948,765 - 11,994,838 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PARPBP
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	102,120,183 - 102,197,520 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	102,120,183 - 102,197,520 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	102,513,961 - 102,591,298 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	101,038,086 - 101,115,428 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	12	102,177,976 - 102,255,257 (+)	NCBI		Celera
Cytogenetic Map	12	q23.2	NCBI
HuRef	12	99,573,544 - 99,650,766 (+)	NCBI		HuRef
CHM1_1	12	102,480,622 - 102,557,963 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	102,081,315 - 102,158,656 (+)	NCBI		T2T-CHM13v2.0

Parpbp
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	87,927,260 - 87,982,831 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	87,927,294 - 87,982,803 (-)	Ensembl		GRCm39 Ensembl
GRCm38	10	88,091,398 - 88,146,969 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	88,091,432 - 88,146,941 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	87,554,143 - 87,609,686 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	87,554,143 - 87,609,686 (-)	NCBI		MGSCv36	mm8
Celera	10	90,076,046 - 90,124,027 (-)	NCBI		Celera
Cytogenetic Map	10	C1	NCBI
cM Map	10	43.7	NCBI

Parpbp
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	24,398,897 - 24,468,330 (-)	NCBI		GRCr8
mRatBN7.2	7	22,511,427 - 22,580,834 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	22,511,427 - 22,573,695 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	24,506,078 - 24,568,330 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	26,668,781 - 26,731,039 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	26,445,803 - 26,508,070 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	28,654,707 - 28,724,412 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	28,654,707 - 28,715,224 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	28,764,494 - 28,832,211 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	24,777,634 - 24,847,083 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	7	19,681,545 - 19,736,880 (-)	NCBI		Celera
Cytogenetic Map	7	q13	NCBI

Parpbp
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955405	37,297,329 - 37,361,803 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955405	37,297,816 - 37,357,191 (+)	NCBI	ChiLan1.0	ChiLan1.0

PARPBP
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	110,193,534 - 110,270,852 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	110,189,912 - 110,267,250 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	99,707,641 - 99,784,993 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	103,105,104 - 103,182,366 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	103,105,117 - 103,182,366 (+)	Ensembl	panpan1.1		panPan2

PARPBP
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	15	40,972,098 - 41,039,044 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	15	40,976,598 - 41,036,068 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	15	41,340,064 - 41,407,033 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	15	41,626,400 - 41,693,434 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	15	41,626,510 - 41,691,031 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	15	40,893,493 - 40,960,657 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	15	40,989,550 - 41,056,791 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	15	41,264,005 - 41,331,108 (+)	NCBI		UU_Cfam_GSD_1.0

PARPBP
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	82,019,216 - 82,091,376 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	82,018,857 - 82,091,946 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	85,946,152 - 85,994,211 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PARPBP
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	97,367,270 - 97,437,248 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	97,370,965 - 97,437,967 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	147,567,036 - 147,637,067 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Parpbp
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624750	6,111,050 - 6,163,335 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624750	6,110,357 - 6,163,347 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005322354	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040279256	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000015666 ⟹ ENSSTOP00000014023

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936492	11,948,765 - 11,994,838 (-)	Ensembl

RefSeq Acc Id:

XM_005322354 ⟹ XP_005322411

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404945	18,938,566 - 18,988,550 (-)	NCBI
SpeTri2.0	NW_004936492	11,948,765 - 11,994,838 (-)	NCBI

Sequence:

show sequence

AATGGCTGTGCTTAACCAGAAGTCTGTCTTGGACATGATTAAAGCATTTAGAAGGAACTGGCAT
GTTCTTTGTGATTCTGAAAGAACTACTCTGTGTGGCGCAGACTCCATGCTCTTGGCATTGCAGC
TTTCCATGGCAGAGAACAATAAACAGCACTATGAAGAATTTACAGTCTCTCTCAGTGATGTTTT
AATGACATGGAAATTCTTACTACATGAGAAATTAAACTTACCCATTGAAGATATGGAAGTGGTT
GACCATTATGAAGACATTAAGAAGACTTATGATGATTTTTTGACGAATAGTAATATGGTAGATC
TGATCGACATTTATAAAAAATGTAGGATTTTGACTTCTAATTGTGAAAATAATGACATGATATC
CCCCATTCAACTACTGGATTTTCTCTGTGGCAAAGAGCATGCAGGAGATGATGAAAATGATCTT
TTTATGCCAATGTCACCGGTAAAACACAACCAGGATCATGAAAAGGTACAGCTACTAGCAAAGA
AAGTTATCTTTTCATATTTAAGCCTGCTAGTAAATTCAAAGAATGACCTGGCTCTGGCTCATAT
TCTCAATATTCCTGATAGAGGACTTGGAAGAGAAGCCTTCACTGATTTGAAACATGCTGCTCAA
GAGAAACAGATGTCTATCTATTTGATGGCTACATCCTTTATTAGAACATTAGAACTTGGAGGGA
AAGGCTATGCACCATCACCATCTGATCCTTTAAGGAAACATGTAAAGGGACTGTCTAATTTTAT
TCATTTAATTGACAAATTAAATGAGATTCTCGGAGAAGTATCAAGTCCAAGCATTGCAGGGAGT
CGGATTCTGTCAGTGATAAAGATGCAGCTGACTAAAGGCCAGAACAGCAGGGATCCTTTTTATA
AAGCAGTTGAGGAAGCTGCTCAGGCTTTGGACTTGAGGATTAAAAACATTATCAATTCTCAACA
AGAGGCTGTAGCTGTCAGCACCCCTGACATCAGTCCTGCCCGGCCAAAATCTCATGCCATCAAC
CATGACACATCATACTGTGGCAGAGATACCGTGAAAACTTTACTAGTTCTTTTGGATGAAGAAG
CAGCCCGTGCTCCCACCAGAAACAAAGCAGAGCTTTTATATGGTGACGAAAGCACCATTCATTG
TAATGCAACTTCTATTCTTACACTTTTTACCTCTCCCACACAAGTGAATAACTCATCAGTGAAA
CCCCTAAGAGAACGCATCTATAAGTCAATGCAAGAGAAAAAAAATAAGATGACTCAAACATTAA
TTAGATCGCAGTTTGCTTGTACTTATAAAGATGACTACATGATAAGCAAGGATAAATGGAATAA
CATGAATTCTGCATCAGAACCTTTATGTGTTCTTCATATGGAAAACAACCTTGCTGAGGGTATA
AAATCATCTGTTGGAAAATCAACAATTGCAACAAGTTCTGGAAATGTTCATTTGGACAGAAGTG
AAAATGACAAAGTATCAAGAAAATCAAGTGGCCAGACAGGAAATAAAAGCTCAAAAAGGAAACA
GGTGGATTTGGATGGCGAAAATATTCTCCGTGATAACAGAAATGAACCACCTCAACATAAAAAT
GTTAAGAAACCTAAACCATCAAACGATTCACAGAATAAATTGGATATCGAAGTAACCAAAGTAG
CAAAAGGCAAAAAGTGTACTTCTAAGGCCAAATTCATCACTGGCCAGACAAAATTAACTCAATT
TTTTAGACTATGATTGTGTCTTTTATGTGTTTTAGATTTATGCATATGGAAAGCTGTACACCAA
AGTCACATGTTTAATTTATAAAAGCTCAAGGTGTCAGTTGTGATGCTTTCAAATTTTTTTTTGA
AGTGAACGTAAGGTTCATGTGATAAGCATTGTTTAAAAACACCACTGAGTCATAATTATGCAGA
ATTTTCACAAAGTTTAATATACAGAAAAAGCACATCATTTAGATTATTGGTATGTCTTAACACT
ACTTTCTTTTAAAGCAGACATTTAAAATAATATACAAGTTATAGGAACATTAAGGGTTT

hide sequence

RefSeq Acc Id:

XM_040279256 ⟹ XP_040135190

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404945	18,938,566 - 18,988,381 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_005322411	(Get FASTA)	NCBI Sequence Viewer
	XP_040135190	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000014023.2
GenBank Protein	KAG3291139	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005322411 ⟸ XM_005322354

- UniProtKB:

I3MQ48 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAVLNQKSVLDMIKAFRRNWHVLCDSERTTLCGADSMLLALQLSMAENNKQHYEEFTVSLSDVL
MTWKFLLHEKLNLPIEDMEVVDHYEDIKKTYDDFLTNSNMVDLIDIYKKCRILTSNCENNDMIS
PIQLLDFLCGKEHAGDDENDLFMPMSPVKHNQDHEKVQLLAKKVIFSYLSLLVNSKNDLALAHI
LNIPDRGLGREAFTDLKHAAQEKQMSIYLMATSFIRTLELGGKGYAPSPSDPLRKHVKGLSNFI
HLIDKLNEILGEVSSPSIAGSRILSVIKMQLTKGQNSRDPFYKAVEEAAQALDLRIKNIINSQQ
EAVAVSTPDISPARPKSHAINHDTSYCGRDTVKTLLVLLDEEAARAPTRNKAELLYGDESTIHC
NATSILTLFTSPTQVNNSSVKPLRERIYKSMQEKKNKMTQTLIRSQFACTYKDDYMISKDKWNN
MNSASEPLCVLHMENNLAEGIKSSVGKSTIATSSGNVHLDRSENDKVSRKSSGQTGNKSSKRKQ
VDLDGENILRDNRNEPPQHKNVKKPKPSNDSQNKLDIEVTKVAKGKKCTSKAKFITGQTKLTQF
FRL

hide sequence

RefSeq Acc Id:	XP_040135190 ⟸ XM_040279256
- UniProtKB:	I3MQ48 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSSTOP00000014023 ⟸ ENSSTOT00000015666

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000015665	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000015666.3	UniProtKB/TrEMBL
InterPro	P-loop_NTPase	UniProtKB/TrEMBL
	PARPBP	UniProtKB/TrEMBL
NCBI Gene	Parpbp	ENTREZGENE
PANTHER	PCNA-INTERACTING PARTNER	UniProtKB/TrEMBL
	PTHR32121	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
UniProt	I3MQ48	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-08-09	Parpbp	PARP1 binding protein	LOC101969566	PARP1 binding protein	Symbol and/or name change	5135510	APPROVED
2021-03-26	LOC101969566	PARP1 binding protein	Parpbp	PARP1 binding protein	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar