Pof1b (POF1B actin binding protein) - Rat Genome Database

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Gene: Pof1b (POF1B actin binding protein) Ictidomys tridecemlineatus
Analyze
Symbol: Pof1b
Name: POF1B actin binding protein
RGD ID: 12688435
Description: ENCODES a protein that exhibits actin filament binding (inferred); INVOLVED IN actin cytoskeleton organization (inferred); actin filament organization (inferred); bicellular tight junction assembly (inferred); ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); non-syndromic X-linked intellectual disability (ortholog); FOUND IN actin filament (inferred); adherens junction (inferred); bicellular tight junction (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: premature ovarian failure, 1B; premature ovarian failure, 1B, transcript variant X1; premature ovarian failure, 1B, transcript variant X2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X59,709,734 - 59,781,039 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365476,029,831 - 6,101,451 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365476,031,281 - 6,101,451 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Pof1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X59,709,734 - 59,781,039 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365476,029,831 - 6,101,451 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365476,031,281 - 6,101,451 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
POF1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X85,277,396 - 85,379,665 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX85,277,396 - 85,379,717 (-)EnsemblGRCh38hg38GRCh38
GRCh37X84,532,402 - 84,634,670 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X84,419,058 - 84,521,404 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X84,338,546 - 84,440,893NCBI
CeleraX84,771,759 - 84,874,115 (-)NCBICelera
Cytogenetic MapXq21.1NCBI
HuRefX78,105,395 - 78,207,259 (-)NCBIHuRef
CHM1_1X84,426,026 - 84,528,381 (-)NCBICHM1_1
T2T-CHM13v2.0X83,705,917 - 83,808,182 (-)NCBIT2T-CHM13v2.0
Pof1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X111,548,124 - 111,608,408 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX111,548,128 - 111,608,348 (-)EnsemblGRCm39 Ensembl
GRCm38X112,638,427 - 112,698,711 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX112,638,431 - 112,698,651 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X109,752,036 - 109,812,260 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X108,755,371 - 108,815,595 (-)NCBIMGSCv36mm8
CeleraX99,259,694 - 99,319,351 (-)NCBICelera
Cytogenetic MapXE1NCBI
cM MapX48.76NCBI
Pof1b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X81,875,348 - 81,942,046 (-)NCBIGRCr8
mRatBN7.2X77,683,128 - 77,749,827 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX77,683,128 - 77,749,688 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX79,341,070 - 79,405,975 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X82,771,162 - 82,836,183 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X80,359,561 - 80,426,136 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X84,099,618 - 84,167,717 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX84,099,618 - 84,167,717 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X84,048,665 - 84,115,822 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X101,220,259 - 101,288,788 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX78,983,162 - 79,047,222 (-)NCBICelera
Cytogenetic MapXq31NCBI
Pof1b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555294,136,480 - 4,224,537 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555294,137,746 - 4,224,542 (-)NCBIChiLan1.0ChiLan1.0
POF1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X84,754,788 - 84,851,564 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X84,758,395 - 84,855,171 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X74,347,322 - 74,444,182 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X84,457,716 - 84,554,569 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX84,457,716 - 84,554,627 (-)Ensemblpanpan1.1panPan2
POF1B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X66,233,225 - 66,342,297 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX66,214,255 - 66,342,904 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX56,990,661 - 57,099,614 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X67,569,114 - 67,673,467 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX67,545,959 - 67,673,419 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X65,212,794 - 65,321,752 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X66,849,598 - 66,958,554 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X66,441,806 - 66,550,764 (-)NCBIUU_Cfam_GSD_1.0
POF1B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX68,503,179 - 68,579,893 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X68,503,170 - 68,579,917 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X78,325,924 - 78,402,665 (-)NCBISscrofa10.2Sscrofa10.2susScr3
POF1B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X74,126,425 - 74,234,330 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660676,604,398 - 6,711,359 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pof1b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248523,022,251 - 3,134,418 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248523,022,251 - 3,136,807 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000011726   ⟹   ENSSTOP00000010521
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365476,029,831 - 6,101,451 (-)Ensembl
RefSeq Acc Id: XM_005328841   ⟹   XP_005328898
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X59,714,394 - 59,781,039 (-)NCBI
SpeTri2.0NW_0049365476,034,806 - 6,101,451 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005328842   ⟹   XP_005328899
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2X59,709,734 - 59,781,039 (-)NCBI
SpeTri2.0NW_0049365476,031,281 - 6,101,451 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005328898 (Get FASTA)   NCBI Sequence Viewer  
  XP_005328899 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000010521.3
GenBank Protein KAG3272526 (Get FASTA)   NCBI Sequence Viewer  
  KAG3272527 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005328899   ⟸   XM_005328842
- Peptide Label: isoform X2
- UniProtKB: I3MHW2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005328898   ⟸   XM_005328841
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSSTOP00000010521   ⟸   ENSSTOT00000011726


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000011717 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000011726.3 UniProtKB/TrEMBL
InterPro POF1B UniProtKB/TrEMBL
NCBI Gene Pof1b ENTREZGENE
PANTHER PROTEIN POF1B UniProtKB/TrEMBL
  PTHR22546 UniProtKB/TrEMBL
UniProt I3MHW2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-29 Pof1b  POF1B actin binding protein    POF1B, actin binding protein  Symbol and/or name change 5135510 APPROVED
2017-08-15 Pof1b  POF1B, actin binding protein    premature ovarian failure, 1B  Symbol and/or name change 5135510 APPROVED