Cetn2 (centrin 2) - Rat Genome Database

Name: Cetn2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Cetn2 (centrin 2) Ictidomys tridecemlineatus

Analyze

Symbol:

Cetn2

Name:

centrin 2

RGD ID:

12687296

Description:

ENCODES a protein that exhibits calcium ion binding (inferred); G-protein beta/gamma-subunit complex binding (inferred); heterotrimeric G-protein binding (inferred); INVOLVED IN centriole replication (inferred); mitotic cell cycle (inferred); nucleotide-excision repair (inferred); PARTICIPATES IN nucleotide excision repair pathway; ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); syndromic X-linked intellectual disability Lubs type (ortholog); FOUND IN centrosome (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

centrin-2

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CETN2 (centrin 2)	NCBI	Ortholog
Mus musculus (house mouse):	Cetn2 (centrin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Cetn2 (centrin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cetn2 (centrin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CETN2 (centrin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CETN2 (centrin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CETN2 (centrin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CETN2 (centrin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cetn2 (centrin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	117,977,261 - 117,982,406 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936714	274,036 - 279,381 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936714	274,098 - 279,177 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

genetic disease (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

centriole replication (IEA)

mitotic cell cycle (IEA)

nucleotide-excision repair (IEA)

regulation of cytokinesis (IEA)

spermatogenesis (IEA)

Cellular Component

9+2 motile cilium (IEA)

apical part of cell (IEA)

centriole (IEA)

centrosome (IEA,ISO)

ciliary basal body (IEA)

cilium (IEA)

microtubule organizing center (IEA)

nuclear pore nuclear basket (IEA)

photoreceptor connecting cilium (IEA)

transcription export complex 2 (IEA)

XPC complex (IEA)

Molecular Function

calcium ion binding (IEA)

G-protein beta/gamma-subunit complex binding (IEA)

heterotrimeric G-protein binding (IEA)

metal ion binding (IEA)

microtubule binding (IEA)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

nucleotide excision repair pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Cetn2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	117,977,261 - 117,982,406 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936714	274,036 - 279,381 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936714	274,098 - 279,177 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CETN2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	152,826,994 - 152,830,757 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	152,826,994 - 152,830,757 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	151,995,538 - 151,999,301 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	151,746,527 - 151,749,957 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	151,666,440 - 151,669,869	NCBI
Celera	X	152,330,255 - 152,333,685 (-)	NCBI		Celera
Cytogenetic Map	X	q28	NCBI
CHM1_1	X	151,870,461 - 151,873,892 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	X	151,093,478 - 151,097,241 (-)	NCBI		T2T-CHM13v2.0

Cetn2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	71,957,137 - 71,961,967 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	71,957,138 - 71,962,017 (-)	Ensembl		GRCm39 Ensembl
GRCm38	X	72,913,565 - 72,918,344 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	72,913,532 - 72,918,411 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	70,158,904 - 70,163,683 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	69,166,285 - 69,171,064 (-)	NCBI		MGSCv36	mm8
Celera	X	63,848,732 - 63,853,510 (-)	NCBI		Celera
Cytogenetic Map	X	A7.3	NCBI
cM Map	X	37.29	NCBI

Cetn2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	155,812,212 - 155,817,186 (-)	NCBI		GRCr8
mRatBN7.2	X	150,769,944 - 150,774,833 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	150,769,953 - 150,774,919 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	152,961,970 - 152,966,859 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	156,494,314 - 156,499,203 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	154,037,424 - 154,042,313 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	152,927,852 - 152,933,095 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	152,927,718 - 152,932,953 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	148,656,625 - 148,661,864 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	158,917,650 - 158,923,210 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	X	158,991,770 - 158,994,109 (-)	NCBI
Celera	1	131,733,984 - 131,739,094 (-)	NCBI		Celera
Cytogenetic Map	X	q37	NCBI

Cetn2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955498	8,131,295 - 8,135,751 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955498	8,131,356 - 8,135,751 (-)	NCBI	ChiLan1.0	ChiLan1.0

CETN2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	152,891,513 - 152,895,020 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	152,895,116 - 152,898,630 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	142,401,679 - 142,405,206 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	152,320,893 - 152,324,362 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	152,320,893 - 152,324,362 (-)	Ensembl	panpan1.1		panPan2

CETN2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	120,714,676 - 120,720,012 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	106,083,242 - 106,088,561 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	122,939,332 - 122,944,667 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	122,939,337 - 122,944,584 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	119,655,565 - 119,660,884 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	122,146,252 - 122,151,579 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	122,021,281 - 122,026,614 (-)	NCBI		UU_Cfam_GSD_1.0

CETN2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	123,902,241 - 123,906,230 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	123,902,240 - 123,906,046 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	141,372,858 - 141,376,715 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CETN2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	127,339,163 - 127,342,626 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	127,338,862 - 127,341,575 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666065	65,172,423 - 65,175,920 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cetn2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624883	4,035,647 - 4,039,732 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624883	4,035,647 - 4,039,758 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005338503	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040286833	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040286836	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000614	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000029035 ⟹ ENSSTOP00000020634

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936714	274,036 - 279,381 (+)	Ensembl

RefSeq Acc Id:

XM_005338503 ⟹ XP_005338560

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	X	117,977,261 - 117,982,406 (-)	NCBI
SpeTri2.0	NW_004936714	274,098 - 279,177 (+)	NCBI

Sequence:

show sequence

GCGCGCGCGCGGGACAGTGGGAACAGCGGGCACCTAATCTGTGTGTACGCCGTTGCTGTAACAA
CCAACAGTGGAGTTCTTTTGCAATGGCCTCCAATTTTAAGAAGGCAAATATGGCATCAAGTGCC
CAGCGAAAAAGGATGAGTCCTAAGCCAGAGCTTACTGAAGAGCAGAAGCAAGAAATTCGGGAAG
CTTTTGATCTCTTTGATGCTGATGGAACTGGGACCATAGATATTAAGGAACTAAAGGTGGCAAT
GAGAGCCCTGGGCTTTGAACCTAAGAAAGAAGAAATCAAGAAAATGATAAGTGAAATTGACAAA
GAAGGGACAGGAAAAATGAATTTCAGTGACTTTTTGACTGTGATGACTCAGAAAATGTCTGAGA
AAGATACCAAAGAAGAAATCCTGAAAGCTTTCAAGCTCTTTGATGATGATGAAACTGGAAAGAT
ATCATTCAAGAATCTGAAGCGCGTGGCCAAAGAGTTGGGTGAGAACCTGACTGATGAGGAGCTA
CAGGAAATGATTGATGAAGCTGATCGAGATGGAGATGGAGAGGTCAATGAGCAGGAGTTCCTGC
GCATCATGAAAAAGACCAGCCTCTATTAACTTCAGTGTCTTCTGTTCTACTGCAAGCACACGTG
ACTAGATTTAGTGCCTGCCATTGTGTGAAATCTGGCTTTTGAGAACACAACCCCCCACTATCCT
GAATAACTTTCCTCATGACCTTGAGTCTATTTTAGATTTTTGGAAGAAGTCTTTGATATTAAAG
TTCTTTGTAAAATGACCTACCAATTTAATTCTCAAAAGCAGAATGAGAGCACATTAGAGTGGAG
AAAAGGGGCTTAAAGTTTGACTACCTGCCATTTCACATTGCATTGCTTCACTTTTGTCATGCAT
TTCCACATAGATACAAACACAAAACAACTTCTTAGACAAGCACATGTTGTACTTATGTCACCAC
AAGCAGTGGTCATTCTGCAGTGGTTCTGATTGCTAGTTGAAACCTGTATGTGGTTTTCTCTTTT
ATAAAATCCAGTGAACTCTTTCTCTGGCATTTGTATGTGTGTTAATGCTATTTATTTTGTCAGG
AAAAATAAAACCTTTCTTAATTTGA

hide sequence

RefSeq Acc Id:

XM_040286833 ⟹ XP_040142767

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	X	117,977,261 - 117,981,638 (-)	NCBI

RefSeq Acc Id:

XM_040286836 ⟹ XP_040142770

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	X	117,977,261 - 117,981,844 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_005338560	(Get FASTA)	NCBI Sequence Viewer
	XP_040142767	(Get FASTA)	NCBI Sequence Viewer
	XP_040142770	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000020634.1
GenBank Protein	KAG3273145	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005338560 ⟸ XM_005338503
- Peptide Label:	isoform X1
- UniProtKB:	I3N8D8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MASNFKKANMASSAQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDIKELKVAMRALGFEP KKEEIKKMISEIDKEGTGKMNFSDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKR VAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIMKKTSLY hide sequence

RefSeq Acc Id:	XP_040142770 ⟸ XM_040286836
- Peptide Label:	isoform X3
- UniProtKB:	I3N8D8 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040142767 ⟸ XM_040286833
- Peptide Label:	isoform X2
- UniProtKB:	I3N8D8 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSSTOP00000020634 ⟸ ENSSTOT00000029035

Protein Domains

EF-hand

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000023853	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000029035.2	UniProtKB/TrEMBL
Gene3D-CATH	EF-hand	UniProtKB/TrEMBL
InterPro	EF-hand-dom_pair	UniProtKB/TrEMBL
	EF_Hand_1_Ca_BS	UniProtKB/TrEMBL
	EF_hand_dom	UniProtKB/TrEMBL
	RNA-helicase_DEAD-box_CS	UniProtKB/TrEMBL
NCBI Gene	Cetn2	ENTREZGENE
PANTHER	CALCIUM BINDING PROTEIN	UniProtKB/TrEMBL
	PTHR23050:SF305	UniProtKB/TrEMBL
Pfam	EF-hand_7	UniProtKB/TrEMBL
PROSITE	DEAD_ATP_HELICASE	UniProtKB/TrEMBL
	EF_HAND_1	UniProtKB/TrEMBL
	EF_HAND_2	UniProtKB/TrEMBL
SMART	EFh	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47473	UniProtKB/TrEMBL
UniProt	I3N8D8	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

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