Frs2 (fibroblast growth factor receptor substrate 2) - Rat Genome Database

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Gene: Frs2 (fibroblast growth factor receptor substrate 2) Ictidomys tridecemlineatus
Analyze
Symbol: Frs2
Name: fibroblast growth factor receptor substrate 2
RGD ID: 12682051
Description: ENCODES a protein that exhibits fibroblast growth factor receptor binding (ortholog); neurotrophin TRKA receptor binding (ortholog); transmembrane receptor protein tyrosine kinase adaptor activity (ortholog); INVOLVED IN anterior/posterior axis specification, embryo (ortholog); cellular response to fibroblast growth factor stimulus (ortholog); fibroblast growth factor receptor signaling pathway (ortholog); PARTICIPATES IN brain-derived neurotrophic factor signaling pathway; fibroblast growth factor signaling pathway; ASSOCIATED WITH renal cell carcinoma (ortholog); FOUND IN adherens junction (ortholog); cell-cell junction (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: fibroblast growth factor receptor substrate 2, transcript variant X1; fibroblast growth factor receptor substrate 2, transcript variant X2; fibroblast growth factor receptor substrate 2, transcript variant X3; fibroblast growth factor receptor substrate 2, transcript variant X4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494546,703,111 - 46,824,118 (-)NCBI
SpeTri2.0NW_0049365457,286,018 - 7,407,623 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Frs2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494546,703,111 - 46,824,118 (-)NCBI
SpeTri2.0NW_0049365457,286,018 - 7,407,623 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FRS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1269,470,349 - 69,579,793 (+)EnsemblGRCh38hg38GRCh38
GRCh381269,470,371 - 69,579,793 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371269,864,168 - 69,973,573 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361268,150,396 - 68,259,829 (+)NCBINCBI36hg18NCBI36
Build 341268,150,452 - 68,255,011NCBI
Celera1269,527,782 - 69,637,211 (+)NCBI
Cytogenetic Map12q15NCBI
HuRef1266,913,617 - 67,023,032 (+)NCBIHuRef
CHM1_11269,832,586 - 69,941,996 (+)NCBICHM1_1
Frs2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910116,905,330 - 116,984,442 (-)NCBIGRCm39mm39
GRCm39 Ensembl10116,905,332 - 116,984,439 (-)Ensembl
GRCm3810117,070,127 - 117,148,474 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10117,069,427 - 117,148,534 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710116,507,183 - 116,585,530 (-)NCBIGRCm37mm9NCBIm37
MGSCv3610116,474,237 - 116,552,584 (-)NCBImm8
Celera10119,013,278 - 119,091,626 (-)NCBICelera
Cytogenetic Map10D2NCBI
Frs2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2752,711,255 - 52,792,758 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl752,711,257 - 52,792,743 (-)Ensembl
Rnor_6.0760,128,506 - 60,210,482 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl760,128,508 - 60,210,518 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0760,128,589 - 60,210,278 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4756,409,863 - 56,490,535 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1756,435,173 - 56,446,435 (-)NCBI
Celera749,486,845 - 49,568,253 (-)NCBICelera
Cytogenetic Map7q22NCBI
Frs2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554059,843,925 - 9,884,220 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554059,785,857 - 9,884,220 (+)NCBIChiLan1.0ChiLan1.0
FRS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11269,767,526 - 69,878,293 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1269,829,435 - 69,878,293 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01266,992,207 - 67,107,313 (+)NCBIMhudiblu_PPA_v0panPan3
FRS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11011,445,843 - 11,552,325 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1011,539,994 - 11,552,890 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1011,377,588 - 11,487,799 (+)NCBI
ROS_Cfam_1.01011,569,128 - 11,679,363 (+)NCBI
UMICH_Zoey_3.11011,436,282 - 11,546,368 (+)NCBI
UNSW_CanFamBas_1.01011,683,256 - 11,793,428 (+)NCBI
UU_Cfam_GSD_1.01011,806,052 - 11,916,601 (+)NCBI
FRS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl533,725,444 - 33,849,976 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1533,725,432 - 33,852,952 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2536,346,044 - 36,385,117 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FRS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11165,097,789 - 65,208,373 (+)NCBI
ChlSab1.1 Ensembl1165,197,385 - 65,208,379 (+)Ensembl
Vero_WHO_p1.0NW_023666037180,481,351 - 180,595,730 (-)NCBI
Frs2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475028,224,289 - 28,359,473 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005328733   ⟹   XP_005328790
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494546,703,111 - 46,824,118 (-)NCBI
SpeTri2.0NW_0049365457,286,018 - 7,407,623 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021728695   ⟹   XP_021584370
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_0049365457,354,467 - 7,407,623 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021728696   ⟹   XP_021584371
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494546,703,111 - 46,729,955 (-)NCBI
SpeTri2.0NW_0049365457,380,161 - 7,407,623 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021728697   ⟹   XP_021584372
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494546,703,111 - 46,751,690 (-)NCBI
SpeTri2.0NW_0049365457,391,834 - 7,407,623 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040280334   ⟹   XP_040136268
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494546,703,111 - 46,751,725 (-)NCBI
RefSeq Acc Id: XM_040280335   ⟹   XP_040136269
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494546,703,111 - 46,751,725 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_005328790   ⟸   XM_005328733
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_021584370   ⟸   XM_021728695
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_021584371   ⟸   XM_021728696
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_021584372   ⟸   XM_021728697
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_040136268   ⟸   XM_040280334
- Peptide Label: isoform X2
RefSeq Acc Id: XP_040136269   ⟸   XM_040280335
- Peptide Label: isoform X4


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000014028 ENTREZGENE
Ensembl Protein ENSSTOP00000012569 ENTREZGENE
NCBI Gene Frs2 ENTREZGENE