Upb1 (beta-ureidopropionase 1) - Rat Genome Database
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Gene: Upb1 (beta-ureidopropionase 1) Ictidomys tridecemlineatus
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Symbol: Upb1
Name: beta-ureidopropionase 1
RGD ID: 12681056
Description: ENCODES a protein that exhibits beta-ureidopropionase activity (ortholog); protein homodimerization activity (ortholog); zinc ion binding (ortholog); INVOLVED IN beta-alanine biosynthetic process via 3-ureidopropionate (ortholog); beta-alanine metabolic process (ortholog); CMP catabolic process (ortholog); PARTICIPATES IN beta-alanine metabolic pathway; beta-ureidopropionase deficiency pathway; carnosinemia pathway; ASSOCIATED WITH autistic disorder (ortholog); Beta-Ureidopropionase Deficiency (ortholog); celiac disease (ortholog); FOUND IN cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: beta-ureidopropionase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936619668,380 - 713,720 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (ISO)

Molecular Function

References

Genomics

Comparative Map Data
Upb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936619668,380 - 713,720 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UPB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2224,494,107 - 24,528,390 (+)EnsemblGRCh38hg38GRCh38
GRCh382224,495,060 - 24,528,681 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372224,891,300 - 24,924,358 (+)NCBIGRCh37GRCh37hg19GRCh37
GRCh372224,863,344 - 24,922,553 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362223,221,251 - 23,252,553 (+)NCBINCBI36hg18NCBI36
Build 342223,215,804 - 23,247,106NCBI
Celera228,690,987 - 8,722,274 (+)NCBI
Cytogenetic Map22q11.23NCBI
HuRef227,840,918 - 7,872,203 (+)NCBIHuRef
CHM1_12224,849,971 - 24,881,302 (+)NCBICHM1_1
Upb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391075,242,745 - 75,277,513 (+)NCBIGRCm39mm39
GRCm381075,406,911 - 75,441,679 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1075,401,115 - 75,441,679 (+)EnsemblGRCm38mm10GRCm38
MGSCv371074,869,779 - 74,902,942 (+)NCBIGRCm37mm9NCBIm37
MGSCv361074,846,181 - 74,883,913 (+)NCBImm8
Celera1076,453,987 - 76,488,021 (+)NCBICelera
Cytogenetic Map10C1NCBI
Upb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22013,217,252 - 13,243,590 (-)NCBI
Rnor_6.0 Ensembl2014,167,586 - 14,193,690 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.02014,167,383 - 14,193,724 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02016,352,599 - 16,378,743 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42013,715,995 - 13,743,261 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12013,716,221 - 13,743,488 (-)NCBI
Celera2014,703,097 - 14,729,538 (-)NCBICelera
Cytogenetic Map20p12NCBI
Upb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554557,961,264 - 7,995,946 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554557,961,296 - 7,992,235 (+)NCBIChiLan1.0ChiLan1.0
UPB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12222,138,989 - 22,197,360 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2222,166,370 - 22,197,360 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0225,300,686 - 5,332,735 (+)NCBIMhudiblu_PPA_v0panPan3
UPB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2628,195,081 - 28,225,567 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12628,194,968 - 28,225,977 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
UPB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1449,533,226 - 49,565,100 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11449,533,208 - 49,561,518 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21452,975,014 - 53,003,329 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UPB1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1197,605,999 - 7,639,339 (-)NCBI
ChlSab1.1 Ensembl197,605,537 - 7,639,017 (-)Ensembl
Upb1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247479,911,323 - 9,940,770 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005334449   ⟹   XP_005334506
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_004936619668,380 - 696,269 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021732633   ⟹   XP_021588308
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_004936619668,380 - 709,362 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021732634   ⟹   XP_021588309
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_004936619668,380 - 713,720 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021732635   ⟹   XP_021588310
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_004936619668,393 - 696,269 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005334506 (Get FASTA)   NCBI Sequence Viewer  
  XP_021588308 (Get FASTA)   NCBI Sequence Viewer  
  XP_021588309 (Get FASTA)   NCBI Sequence Viewer  
  XP_021588310 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005334506   ⟸   XM_005334449
- Peptide Label: isoform X1
- UniProtKB: I3LW29 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021588309   ⟸   XM_021732634
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_021588308   ⟸   XM_021732633
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_021588310   ⟸   XM_021732635
- Peptide Label: isoform X2
- Sequence:
Protein Domains
CN hydrolase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000000161 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000000142 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000000162 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.60.110.10 UniProtKB/TrEMBL
InterPro C-N_Hydrolase UniProtKB/TrEMBL
  C-N_Hydrolase_sf UniProtKB/TrEMBL
NCBI Gene Upb1 ENTREZGENE
Pfam CN_hydrolase UniProtKB/TrEMBL
PROSITE CN_HYDROLASE UniProtKB/TrEMBL
Superfamily-SCOP SSF56317 UniProtKB/TrEMBL
UniProt I3LW29 ENTREZGENE, UniProtKB/TrEMBL