Stxbp1 (syntaxin binding protein 1)

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Gene: Stxbp1 (syntaxin binding protein 1) Ictidomys tridecemlineatus

Analyze

Symbol:

Stxbp1

Name:

syntaxin binding protein 1

RGD ID:

12680934

Description:

ENCODES a protein that exhibits identical protein binding (ortholog); phospholipase binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN axon target recognition (ortholog); cellular response to interferon-gamma (ortholog); developmental process involved in reproduction (ortholog); PARTICIPATES IN insulin secretion pathway; synaptic vesicle exocytosis - neurotransmitter release pathway; ASSOCIATED WITH autistic disorder (ortholog); Bardet-Biedl syndrome 1 (ortholog); Bardet-Biedl syndrome 17 (ortholog); FOUND IN axon (ortholog); cytoplasm (ortholog); cytoskeleton (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Also known as:

syntaxin-binding protein 1

RGD Orthologs

Human

Mouse

Rat

Chinchilla

Bonobo

Dog

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936487	15,300,758 - 15,367,475 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

Bardet-Biedl syndrome 1 (ISO)

Bardet-Biedl syndrome 17 (ISO)

cerebellar hypoplasia (ISO)

childhood onset epileptic encephalopathy (ISO)

congenital disorder of glycosylation Iu (ISO)

developmental and epileptic encephalopathy (ISO)

developmental and epileptic encephalopathy 1 (ISO)

developmental and epileptic encephalopathy 4 (ISO)

Developmental Disabilities (ISO)

Duchenne muscular dystrophy (ISO)

early infantile epileptic encephalopathy (ISO)

epilepsy (ISO)

Generalized Epilepsy (ISO)

genetic disease (ISO)

intellectual disability (ISO)

microcephaly (ISO)

Muscle Spasticity (ISO)

Myoclonic Epilepsies (ISO)

Neurodevelopmental Disorders (ISO)

non-syndromic intellectual disability (ISO)

prostate cancer (ISO)

salt and pepper syndrome (ISO)

visual epilepsy (ISO)

West syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

axon target recognition (ISO)

cellular response to interferon-gamma (ISO)

developmental process involved in reproduction (ISO)

exocytosis (ISO)

long-term synaptic depression (ISO)

negative regulation of neuron apoptotic process (ISO)

negative regulation of protein-containing complex assembly (ISO)

negative regulation of synaptic transmission, GABAergic (ISO)

neuromuscular synaptic transmission (ISO)

neurotransmitter secretion (ISO)

platelet aggregation (ISO)

platelet degranulation (ISO)

positive regulation of calcium ion-dependent exocytosis (ISO)

positive regulation of exocytosis (ISO)

positive regulation of glutamate secretion, neurotransmission (ISO)

positive regulation of mast cell degranulation (ISO)

positive regulation of vesicle docking (ISO)

presynaptic dense core vesicle exocytosis (ISO)

protein localization to plasma membrane (ISO)

protein stabilization (ISO)

regulation of acrosomal vesicle exocytosis (ISO)

regulation of synaptic vesicle priming (ISO)

regulation of vesicle fusion (ISO)

response to estradiol (ISO)

SNARE complex assembly (ISO)

synaptic vesicle maturation (ISO)

synaptic vesicle priming (ISO)

vesicle docking involved in exocytosis (ISO)

Cellular Component

axon (ISO)

cytoplasm (ISO)

cytoskeleton (ISO)

cytosol (ISO)

glutamatergic synapse (ISO)

nucleoplasm (ISO)

nucleus (ISO)

perinuclear region of cytoplasm (ISO)

phagocytic vesicle (ISO)

plasma membrane (ISO)

platelet alpha granule (ISO)

postsynapse (ISO)

presynapse (ISO)

presynaptic active zone membrane (ISO)

protein-containing complex (ISO)

Molecular Function

identical protein binding (ISO)

phospholipase binding (ISO)

protein binding (ISO)

protein domain specific binding (ISO)

protein kinase binding (ISO)

protein N-terminus binding (ISO)

SNARE binding (ISO)

syntaxin binding (ISO)

syntaxin-1 binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

insulin secretion pathway (ISO)

synaptic vesicle exocytosis - neurotransmitter release pathway (ISO)

References

Genomics

Comparative Map Data

Stxbp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936487	15,300,758 - 15,367,475 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

STXBP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	9	127,579,370 - 127,696,027 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	9	127,611,912 - 127,696,029 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	9	130,374,191 - 130,458,308 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
GRCh37	9	130,374,486 - 130,454,995 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	129,414,390 - 129,494,816 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	9	127,454,121 - 127,534,549	NCBI
Celera	9	101,025,378 - 101,105,881 (+)	NCBI
Cytogenetic Map	9	q34.11	NCBI
HuRef	9	99,990,647 - 100,071,101 (+)	NCBI		HuRef
CHM1_1	9	130,525,679 - 130,606,190 (+)	NCBI		CHM1_1

Stxbp1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	32,677,619 - 32,737,249 (-)	NCBI	GRCm39		mm39
GRCm38	2	32,787,607 - 32,847,237 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	32,787,602 - 32,847,245 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	32,643,127 - 32,702,757 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	2	32,609,971 - 32,669,135 (-)	NCBI			mm8
Celera	2	32,494,462 - 32,554,183 (-)	NCBI		Celera
Cytogenetic Map	2	B	NCBI
cM Map	2	22.09	NCBI

Stxbp1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	3	16,076,725 - 16,138,431 (-)	NCBI
Rnor_6.0 Ensembl	3	11,823,785 - 11,885,417 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	3	11,823,779 - 11,885,479 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	3	17,160,752 - 17,221,893 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	11,762,105 - 11,825,531 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	3	11,658,476 - 11,721,903 (-)	NCBI
Celera	3	10,816,317 - 10,877,576 (-)	NCBI		Celera
RH 3.4 Map	3	79.6	RGD
Cytogenetic Map	3	p11	NCBI

Stxbp1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955419	963,829 - 1,000,759 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955419	963,829 - 1,000,759 (-)	NCBI	ChiLan1.0	ChiLan1.0

STXBP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	9	127,434,080 - 127,483,971 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	127,434,080 - 127,486,152 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	9	98,731,527 - 98,811,608 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

STXBP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	9	55,678,264 - 55,727,680 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	9	55,690,939 - 55,768,008 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

STXBP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	268,116,118 - 268,213,921 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	268,116,124 - 268,205,805 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	302,023,293 - 302,098,188 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

STXBP1
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	10,440,061 - 10,519,798 (-)	NCBI
ChlSab1.1 Ensembl	12	10,439,801 - 10,519,777 (-)	Ensembl

Stxbp1
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624760	7,843,741 - 7,914,444 (-)	NCBI

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005320989	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005320990	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGTP01020061	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AGTP01020062	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

XM_005320989 ⟹ XP_005321046

RefSeq Status:

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0	NW_004936487	15,300,758 - 15,367,475 (+)	NCBI

Sequence:

show sequence

CCCGCGCGCTCCGGCGGCTCAGCAGCCTCGCTCTGGCTCGGCGCCGCGCCCCCGCGCCGAGTCC
GCGCGTCAGTCGGTCCCGAGAGCGGCAGCGGGGCGGCGGGCTGCAGCCTTCCGAGCGCGCTCTT
GAGGAGACCGCGGTATCTGCGGGCGTCGTGTAAGGAGGCTTGAAGCCCAGAGAATCGCGCAGCG
CCATGGCCCCCATTGGTCTCAAAGCTGTGGTCGGAGAGAAGATCATGCATGATGTGATAAAGAA
GGTGAAGAAGAAGGGGGAGTGGAAGGTGCTGGTGGTGGACCAGCTAAGCATGAGGATGCTCTCC
TCCTGTTGCAAGATGACGGACATCATGACTGAAGGAATAACAATTGTGGAAGACATTAACAAGC
GCAGAGAACCACTCCCCAGCCTGGAGGCTGTGTACCTCATCACCCCATCTGAGAAGTCTGTCCA
CTCTCTCATCAGTGACTTTAAGGACCCACCAACTGCTAAGTACCGGGCTGCACATGTCTTCTTC
ACTGACTCTTGCCCAGATGCCCTGTTTAACGAGCTGGTAAAATCTCGAGCAGCCAAAGTCATCA
AAACGCTGACGGAAATCAACATTGCGTTTCTCCCATATGAATCCCAGGTATATTCCTTGGACTC
TGCTGACTCTTTCCAAAGCTTCTATAGTCCCCACAAAGCTCAGATGAAGAATCCTATACTAGAG
CGCCTGGCAGAGCAGATTGCAACCCTGTGTGCCACCTTGAAGGAGTACCCAGCTGTGCGGTATC
GGGGGGAGTACAAGGACAATGCCTTGCTGGCTCAACTAATCCAGGACAAACTCGACGCCTATAA
AGCTGATGATCCAACCATGGGGGAAGGTCCTGACAAGGCACGCTCCCAGCTGCTGATCCTGGAT
CGGGGCTTTGACCCTAGCTCCCCTGTGCTTCATGAGTTGACTTTTCAGGCCATGAGTTACGACC
TGCTGCCTATTGAAAATGACGTTTACAAGTACGAGACCAGTGGCATTGGGGAGGCACGGGTAAA
GGAAGTGCTCCTGGACGAGGACGACGACCTGTGGATAGCGCTTCGCCACAAGCACATCGCAGAG
GTGTCCCAGGAAGTCACCCGGTCTCTGAAAGACTTTTCTTCTAGCAAGAGAATGAATACTGGAG
AAAAGACCACCATGCGGGACCTGTCCCAGATGCTGAAGAAGATGCCCCAATATCAGAAAGAACT
CAGCAAGTACTCCACCCACCTGCACCTTGCCGAGGACTGCATGAAGCACTACCAAGGCACCGTG
GACAAGCTCTGCCGAGTAGAGCAGGACCTGGCGATGGGCACAGATGCTGAGGGGGAGAAGATCA
AGGACCCCATGAGAGCCATCGTCCCCATTCTGTTGGATGCGAACGTCAGCACTTACGACAAAAT
CCGCATCATCCTCCTCTACATCTTTCTGAAGAACGGCATCACTGAGGAAAACCTGAACAAACTG
ATCCAGCACGCCCAGATCCCCCCAGAGGACAGTGAGATCATCACCAACATGGCCCACCTGGGTG
TGCCCATCGTCACGGATTCCACGCTGCGCCGCAGGAGCAAGCCGGAGCGGAAGGAGCGCATCAG
TGAGCAGACTTACCAGCTCTCACGGTGGACCCCGATTATTAAGGACATCATGGAGGACACAATC
GAGGACAAACTTGACACCAAGCACTACCCGTACATCTCCACCCGCTCCTCTGCCTCCTTCAGCA
CCACTGCTGTCAGCGCCCGCTACGGGCACTGGCACAAGAACAAGGCCCCAGGGGAGTACCGCAG
TGGGCCCCGCCTTATCATTTTCATCCTGGGGGGCGTGAGCCTGAACGAGATGCGCTGTGCTTAC
GAGGTGACCCAGGCCAACGGCAAGTGGGAAGTGCTGATAGGTTCTACTCACATTCTTACTCCCA
CCAAATTTCTCATGGACCTGAGACACCCCGACTTCAGGGAGTCCTCTAGGGTATCTTTTGAGGA
TCAGGCTCCAACAATGGAGTGAGAGCCAAAGAAACAAAGATCCACGCACATTCTCACCCCACAG
AAACTGCTGGACACGCTGAAGAAACTGAATAAAACAGAAGAAGAAATAAGCAGTTAAACAATAA
GCCGCCCCTCCAAGCCGCGCCCTCCCACTGCTCTGAGCCCCTAGCGCAGGCCGGTGTCTTGCTG
CCTCCCCGCCCTGCACGCCCTGGCCGGCCCGCACTGCTCGTGTTTAATGATGCCCTCCTCCAGT
GTGAACCGAGAATAATGCATTGTGTTTTTTAAAAAGATATATATGTATCCTACAAGAAGTTCCT
GTGCAAGCTGCAGAAATTTTGGAATTCTTGAGAATGAATGGACTCCTCCCCCTCATTTATGATC
CTGTGACCTTGTACATAGCCACCTTCGTCGCGTGCAAACTGCTCGAGTACGGAAAGGTAGAAGT
TTGGGTCTTTTAAAAATGTGTATTGGGTTTTTCCTGTTCTTGCTGGGAATCACAGAGCCGTCTG
TGTCCTTCAGGTATTTCACACTGAGGATTAATCTGTTACCTCCTCTCCTGTTCCTATCCCTCGG
TGTCTGCTCACATCCAGATAAGCTGGGAAATGACAATCAGGGGACAGACACCTCACAAAGTTGA
GATGGAACTGGCTCTTTGCTTTCCCTCCCAGCTTGTGCCCCAGAGATGCAGCTGTGGGTGGGGC
TGGAGAGTGTCCATGAGGCCAGGCTGGGTGTCCCCTGGTGTCTTCCACAGTGTGGCCCTGCTTC
CCCAGGCCTGTGGCCACACTGTGTGACCCTGAGAAAGATCCTTCCCAGCCTAGGTCACTATGCA
CAAGACAATGAAAAGCAGACTCCTCCCCAGACGGAGAAGCAGTTAGGGTTGACACACTGACCAG
GTCCCTTGCCTGGGGCATCACCCCTCACAGCTCCTGTTCCCCAGAAGGATCAGCCTGGGTTGAG
TTCAAGGTCAGGACTGGACTGGAACAGGTGGTTCCTGACAGCCGTGGAGAAGGGCCCGTCGAGC
TGATGCTGACGCTGTCCCCACTCCACACGCAGCCTTGTCAGGTTGTCCTCAGTTTAAGATACTT
TGTGGTACTTTATTTTGAGTGATGTGTAGTCATATGTCATCGTGGTTGTGAGAGGCCCATCGTC
TTTCTCCTGTGCAATGGTGTCGCTATGAAGCAGAGGGGAAGAGCAGGTGCTGGAGGTGCGCCCG
TCCCCAGGTCTCGGCAGCTCCCGTCTCAGGAGCGAGCACACGTCGTTCTGCTGCTGTTGTCGTG
AAATATAATGACAGTGGAAGTCACAAAAAATGTCCCCTGCCCCGGCCCTCGCCGCCCTTGCCTC
CCGCAGACTGTGTGTATATTACTGTGTCTCGTGACGTCCTTGCAAACGTGATGTGCGCTTGCCC
CGCCCGCCCGCCCGCCTTCCTTGGAGAATAGTCCTGGACGCACTGTCACTGTGGTGTCCTCTCC
TGCTGGCTCTGGAATCTCCTGTGCACTCTACTTAGCTCCCAGGTCTCCTGTCGCCTTCTCCCCT
TGAGATCCTGCCTCCTTAGGACAGAACCCTAGGACCTGCGCTGGTTGGTTTCTTACGGTCCCCG
CTTGTTTTGTCCCCTCCCTCCGACCAAGCAACGCTCACGCTTTAGAACCTTGTTTGTCAAACAT
GTTGGTTTTCCTTTCTCTGTTATTTATATAAAAAATAATTTATCAAAAGGATATTTTAAAAAAA
AAGCTAGTCTGTCTTGAAACTTGTTTACCTTGAAATTATCAGAATCTCAGTGTTTGAAAGTATT
GAAGCACAAACATGTATCCTCCGTACCGTTCTGTACTGAAGCACTTGAGTCTAATAAATAAAGA
ATCAGCGCCCACTGCTGCTGTCCAGGG

hide sequence

RefSeq Acc Id:

XM_005320990 ⟹ XP_005321047

RefSeq Status:

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0	NW_004936487	15,300,758 - 15,367,475 (+)	NCBI

Sequence:

show sequence

CCCGCGCGCTCCGGCGGCTCAGCAGCCTCGCTCTGGCTCGGCGCCGCGCCCCCGCGCCGAGTCC
GCGCGTCAGTCGGTCCCGAGAGCGGCAGCGGGGCGGCGGGCTGCAGCCTTCCGAGCGCGCTCTT
GAGGAGACCGCGGTATCTGCGGGCGTCGTGTAAGGAGGCTTGAAGCCCAGAGAATCGCGCAGCG
CCATGGCCCCCATTGGTCTCAAAGCTGTGGTCGGAGAGAAGATCATGCATGATGTGATAAAGAA
GGTGAAGAAGAAGGGGGAGTGGAAGGTGCTGGTGGTGGACCAGCTAAGCATGAGGATGCTCTCC
TCCTGTTGCAAGATGACGGACATCATGACTGAAGGAATAACAATTGTGGAAGACATTAACAAGC
GCAGAGAACCACTCCCCAGCCTGGAGGCTGTGTACCTCATCACCCCATCTGAGAAGTCTGTCCA
CTCTCTCATCAGTGACTTTAAGGACCCACCAACTGCTAAGTACCGGGCTGCACATGTCTTCTTC
ACTGACTCTTGCCCAGATGCCCTGTTTAACGAGCTGGTAAAATCTCGAGCAGCCAAAGTCATCA
AAACGCTGACGGAAATCAACATTGCGTTTCTCCCATATGAATCCCAGGTATATTCCTTGGACTC
TGCTGACTCTTTCCAAAGCTTCTATAGTCCCCACAAAGCTCAGATGAAGAATCCTATACTAGAG
CGCCTGGCAGAGCAGATTGCAACCCTGTGTGCCACCTTGAAGGAGTACCCAGCTGTGCGGTATC
GGGGGGAGTACAAGGACAATGCCTTGCTGGCTCAACTAATCCAGGACAAACTCGACGCCTATAA
AGCTGATGATCCAACCATGGGGGAAGGTCCTGACAAGGCACGCTCCCAGCTGCTGATCCTGGAT
CGGGGCTTTGACCCTAGCTCCCCTGTGCTTCATGAGTTGACTTTTCAGGCCATGAGTTACGACC
TGCTGCCTATTGAAAATGACGTTTACAAGTACGAGACCAGTGGCATTGGGGAGGCACGGGTAAA
GGAAGTGCTCCTGGACGAGGACGACGACCTGTGGATAGCGCTTCGCCACAAGCACATCGCAGAG
GTGTCCCAGGAAGTCACCCGGTCTCTGAAAGACTTTTCTTCTAGCAAGAGAATGAATACTGGAG
AAAAGACCACCATGCGGGACCTGTCCCAGATGCTGAAGAAGATGCCCCAATATCAGAAAGAACT
CAGCAAGTACTCCACCCACCTGCACCTTGCCGAGGACTGCATGAAGCACTACCAAGGCACCGTG
GACAAGCTCTGCCGAGTAGAGCAGGACCTGGCGATGGGCACAGATGCTGAGGGGGAGAAGATCA
AGGACCCCATGAGAGCCATCGTCCCCATTCTGTTGGATGCGAACGTCAGCACTTACGACAAAAT
CCGCATCATCCTCCTCTACATCTTTCTGAAGAACGGCATCACTGAGGAAAACCTGAACAAACTG
ATCCAGCACGCCCAGATCCCCCCAGAGGACAGTGAGATCATCACCAACATGGCCCACCTGGGTG
TGCCCATCGTCACGGATTCCACGCTGCGCCGCAGGAGCAAGCCGGAGCGGAAGGAGCGCATCAG
TGAGCAGACTTACCAGCTCTCACGGTGGACCCCGATTATTAAGGACATCATGGAGGACACAATC
GAGGACAAACTTGACACCAAGCACTACCCGTACATCTCCACCCGCTCCTCTGCCTCCTTCAGCA
CCACTGCTGTCAGCGCCCGCTACGGGCACTGGCACAAGAACAAGGCCCCAGGGGAGTACCGCAG
TGGGCCCCGCCTTATCATTTTCATCCTGGGGGGCGTGAGCCTGAACGAGATGCGCTGTGCTTAC
GAGGTGACCCAGGCCAACGGCAAGTGGGAAGTGCTGATAGGATCCACGCACATTCTCACCCCAC
AGAAACTGCTGGACACGCTGAAGAAACTGAATAAAACAGAAGAAGAAATAAGCAGTTAAACAAT
AAGCCGCCCCTCCAAGCCGCGCCCTCCCACTGCTCTGAGCCCCTAGCGCAGGCCGGTGTCTTGC
TGCCTCCCCGCCCTGCACGCCCTGGCCGGCCCGCACTGCTCGTGTTTAATGATGCCCTCCTCCA
GTGTGAACCGAGAATAATGCATTGTGTTTTTTAAAAAGATATATATGTATCCTACAAGAAGTTC
CTGTGCAAGCTGCAGAAATTTTGGAATTCTTGAGAATGAATGGACTCCTCCCCCTCATTTATGA
TCCTGTGACCTTGTACATAGCCACCTTCGTCGCGTGCAAACTGCTCGAGTACGGAAAGGTAGAA
GTTTGGGTCTTTTAAAAATGTGTATTGGGTTTTTCCTGTTCTTGCTGGGAATCACAGAGCCGTC
TGTGTCCTTCAGGTATTTCACACTGAGGATTAATCTGTTACCTCCTCTCCTGTTCCTATCCCTC
GGTGTCTGCTCACATCCAGATAAGCTGGGAAATGACAATCAGGGGACAGACACCTCACAAAGTT
GAGATGGAACTGGCTCTTTGCTTTCCCTCCCAGCTTGTGCCCCAGAGATGCAGCTGTGGGTGGG
GCTGGAGAGTGTCCATGAGGCCAGGCTGGGTGTCCCCTGGTGTCTTCCACAGTGTGGCCCTGCT
TCCCCAGGCCTGTGGCCACACTGTGTGACCCTGAGAAAGATCCTTCCCAGCCTAGGTCACTATG
CACAAGACAATGAAAAGCAGACTCCTCCCCAGACGGAGAAGCAGTTAGGGTTGACACACTGACC
AGGTCCCTTGCCTGGGGCATCACCCCTCACAGCTCCTGTTCCCCAGAAGGATCAGCCTGGGTTG
AGTTCAAGGTCAGGACTGGACTGGAACAGGTGGTTCCTGACAGCCGTGGAGAAGGGCCCGTCGA
GCTGATGCTGACGCTGTCCCCACTCCACACGCAGCCTTGTCAGGTTGTCCTCAGTTTAAGATAC
TTTGTGGTACTTTATTTTGAGTGATGTGTAGTCATATGTCATCGTGGTTGTGAGAGGCCCATCG
TCTTTCTCCTGTGCAATGGTGTCGCTATGAAGCAGAGGGGAAGAGCAGGTGCTGGAGGTGCGCC
CGTCCCCAGGTCTCGGCAGCTCCCGTCTCAGGAGCGAGCACACGTCGTTCTGCTGCTGTTGTCG
TGAAATATAATGACAGTGGAAGTCACAAAAAATGTCCCCTGCCCCGGCCCTCGCCGCCCTTGCC
TCCCGCAGACTGTGTGTATATTACTGTGTCTCGTGACGTCCTTGCAAACGTGATGTGCGCTTGC
CCCGCCCGCCCGCCCGCCTTCCTTGGAGAATAGTCCTGGACGCACTGTCACTGTGGTGTCCTCT
CCTGCTGGCTCTGGAATCTCCTGTGCACTCTACTTAGCTCCCAGGTCTCCTGTCGCCTTCTCCC
CTTGAGATCCTGCCTCCTTAGGACAGAACCCTAGGACCTGCGCTGGTTGGTTTCTTACGGTCCC
CGCTTGTTTTGTCCCCTCCCTCCGACCAAGCAACGCTCACGCTTTAGAACCTTGTTTGTCAAAC
ATGTTGGTTTTCCTTTCTCTGTTATTTATATAAAAAATAATTTATCAAAAGGATATTTTAAAAA
AAAAGCTAGTCTGTCTTGAAACTTGTTTACCTTGAAATTATCAGAATCTCAGTGTTTGAAAGTA
TTGAAGCACAAACATGTATCCTCCGTACCGTTCTGTACTGAAGCACTTGAGTCTAATAAATAAA
GAATCAGCGCCCACTGCTGCTGTCCAGGG

hide sequence

Protein Sequences


Protein RefSeqs	XP_005321046	(Get FASTA)	NCBI Sequence Viewer
	XP_005321047	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

XP_005321047 ⟸ XM_005320990

- Peptide Label:

isoform X2

- Sequence:

show sequence

MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVEDINKR
REPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVKSRAAKVIK
TLTEINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLAEQIATLCATLKEYPAVRYR
GEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPSSPVLHELTFQAMSYDL
LPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGE
KTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQGTVDKLCRVEQDLAMGTDAEGEKIK
DPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENLNKLIQHAQIPPEDSEIITNMAHLGV
PIVTDSTLRRRSKPERKERISEQTYQLSRWTPIIKDIMEDTIEDKLDTKHYPYISTRSSASFST
TAVSARYGHWHKNKAPGEYRSGPRLIIFILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTPQ
KLLDTLKKLNKTEEEISS

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RefSeq Acc Id:

XP_005321046 ⟸ XM_005320989

- Peptide Label:

isoform X1

- Sequence:

show sequence

MAPIGLKAVVGEKIMHDVIKKVKKKGEWKVLVVDQLSMRMLSSCCKMTDIMTEGITIVEDINKR
REPLPSLEAVYLITPSEKSVHSLISDFKDPPTAKYRAAHVFFTDSCPDALFNELVKSRAAKVIK
TLTEINIAFLPYESQVYSLDSADSFQSFYSPHKAQMKNPILERLAEQIATLCATLKEYPAVRYR
GEYKDNALLAQLIQDKLDAYKADDPTMGEGPDKARSQLLILDRGFDPSSPVLHELTFQAMSYDL
LPIENDVYKYETSGIGEARVKEVLLDEDDDLWIALRHKHIAEVSQEVTRSLKDFSSSKRMNTGE
KTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQGTVDKLCRVEQDLAMGTDAEGEKIK
DPMRAIVPILLDANVSTYDKIRIILLYIFLKNGITEENLNKLIQHAQIPPEDSEIITNMAHLGV
PIVTDSTLRRRSKPERKERISEQTYQLSRWTPIIKDIMEDTIEDKLDTKHYPYISTRSSASFST
TAVSARYGHWHKNKAPGEYRSGPRLIIFILGGVSLNEMRCAYEVTQANGKWEVLIGSTHILTPT
KFLMDLRHPDFRESSRVSFEDQAPTME

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Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000008909	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSSTOP00000007989	ENTREZGENE, UniProtKB/TrEMBL
	ENSSTOP00000028650	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000008916	ENTREZGENE, UniProtKB/TrEMBL
	ENSSTOT00000036899	ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.1910	UniProtKB/TrEMBL
	3.40.50.2060	UniProtKB/TrEMBL
	3.90.830.10	UniProtKB/TrEMBL
InterPro	Sec-1-like_dom1	UniProtKB/TrEMBL
	Sec-1-like_dom2	UniProtKB/TrEMBL
	Sec-1-like_dom3a	UniProtKB/TrEMBL
	Sec1-like	UniProtKB/TrEMBL
	Sec1-like_sf	UniProtKB/TrEMBL
NCBI Gene	Stxbp1	ENTREZGENE
PANTHER	PTHR11679	UniProtKB/TrEMBL
Pfam	Sec1	UniProtKB/TrEMBL
PIRSF	VPS45_Sec1	UniProtKB/TrEMBL
Superfamily-SCOP	SSF56815	UniProtKB/TrEMBL
UniProt	A0A287D563_ICTTR	UniProtKB/TrEMBL
	I3MCJ8_ICTTR	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations