Dll1 (delta like canonical Notch ligand 1) - Rat Genome Database

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Gene: Dll1 (delta like canonical Notch ligand 1) Ictidomys tridecemlineatus
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Symbol: Dll1
Name: delta like canonical Notch ligand 1
RGD ID: 12678884
Description: ENCODES a protein that exhibits Notch binding (ortholog); scaffold protein binding (ortholog); Tat protein binding (ortholog); INVOLVED IN astrocyte development (ortholog); cell-cell signaling (ortholog); cerebellar molecular layer formation (ortholog); PARTICIPATES IN Notch signaling pathway; Notch signaling pathway; ASSOCIATED WITH Brain Neoplasms (ortholog); Breast Neoplasms (ortholog); Chronic Pancreatitis (ortholog); FOUND IN adherens junction (ortholog); apical plasma membrane (ortholog); cytoplasmic vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: delta-like protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946151,369,680 - 151,377,618 (+)NCBI
SpeTri2.0NW_004937098212,704 - 220,589 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
astrocyte development  (ISO)
cell-cell signaling  (ISO)
cerebellar molecular layer formation  (ISO)
cerebellar Purkinje cell layer structural organization  (ISO)
clathrin-dependent endocytosis  (ISO)
compartment pattern specification  (ISO)
determination of left/right symmetry  (ISO)
endothelial tip cell fate specification  (ISO)
energy homeostasis  (ISO)
heart looping  (ISO)
inner ear development  (ISO)
lateral inhibition  (ISO)
left/right axis specification  (ISO)
loop of Henle development  (ISO)
marginal zone B cell differentiation  (ISO)
negative regulation of cardiac muscle cell differentiation  (ISO)
negative regulation of cell differentiation  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of epidermal cell differentiation  (ISO)
negative regulation of epithelial cell differentiation  (ISO)
negative regulation of glial cell apoptotic process  (ISO)
negative regulation of inner ear auditory receptor cell differentiation  (ISO)
negative regulation of interleukin-10 production  (ISO)
negative regulation of myeloid cell differentiation  (ISO)
negative regulation of myoblast differentiation  (ISO)
negative regulation of neuron differentiation  (ISO)
nephron development  (ISO)
neuron fate specification  (ISO)
neuronal stem cell population maintenance  (ISO)
Notch signaling pathway  (ISO)
Notch signaling pathway involved in arterial endothelial cell fate commitment  (ISO)
organ growth  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of endocytosis  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of Notch signaling pathway  (ISO)
positive regulation of skeletal muscle tissue growth  (ISO)
positive regulation of sprouting angiogenesis  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
proximal tubule development  (ISO)
proximal/distal pattern formation  (ISO)
regulation of blood pressure  (ISO)
regulation of cell adhesion  (ISO)
regulation of cell division  (ISO)
regulation of growth  (ISO)
regulation of neurogenesis  (ISO)
regulation of skeletal muscle tissue growth  (ISO)
regulation of somitogenesis  (ISO)
regulation of vascular endothelial growth factor signaling pathway  (ISO)
retina development in camera-type eye  (ISO)
retina morphogenesis in camera-type eye  (ISO)
skeletal muscle tissue growth  (ISO)
skin epidermis development  (ISO)
somite specification  (ISO)
somitogenesis  (ISO)
spinal cord development  (ISO)
type B pancreatic cell development  (ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Dll1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946151,369,680 - 151,377,618 (+)NCBI
SpeTri2.0NW_004937098212,704 - 220,589 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DLL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl6170,282,206 - 170,306,565 (-)EnsemblGRCh38hg38GRCh38
GRCh386170,282,200 - 170,291,078 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh376170,591,294 - 170,600,166 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366170,433,219 - 170,441,622 (-)NCBINCBI36hg18NCBI36
Build 346170,508,932 - 170,517,112NCBI
Celera6171,388,861 - 171,397,261 (-)NCBI
Cytogenetic Map6q27NCBI
HuRef6168,098,039 - 168,106,439 (-)NCBIHuRef
CHM1_16170,851,870 - 170,860,273 (-)NCBICHM1_1
Dll1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391715,587,616 - 15,597,275 (-)NCBIGRCm39mm39
GRCm39 Ensembl1715,587,616 - 15,597,134 (-)Ensembl
GRCm381715,367,354 - 15,376,932 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1715,367,354 - 15,376,872 (-)EnsemblGRCm38mm10GRCm38
MGSCv371715,504,318 - 15,512,787 (-)NCBIGRCm37mm9NCBIm37
MGSCv361715,072,317 - 15,080,550 (-)NCBImm8
Celera1716,154,981 - 16,163,462 (-)NCBICelera
Cytogenetic Map17A2NCBI
cM Map178.95NCBI
Dll1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2156,312,062 - 56,320,177 (-)NCBImRatBN7.2
Rnor_6.0 Ensembl157,318,708 - 57,327,379 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0157,318,621 - 57,326,732 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01242,107,684 - 242,115,795 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4154,240,395 - 54,248,183 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1154,243,339 - 54,251,125 (-)NCBI
Celera152,521,212 - 52,529,325 (-)NCBICelera
Cytogenetic Map1q12NCBI
Dll1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554113,478,033 - 3,486,604 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554113,478,943 - 3,486,541 (+)NCBIChiLan1.0ChiLan1.0
DLL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.16173,535,941 - 173,545,362 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6173,534,292 - 173,544,759 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v06168,440,192 - 168,449,071 (-)NCBIMhudiblu_PPA_v0panPan3
DLL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11272,265,078 - 72,272,347 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1272,265,682 - 72,272,348 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1272,029,118 - 72,036,680 (-)NCBI
ROS_Cfam_1.01273,251,013 - 73,258,571 (-)NCBI
UMICH_Zoey_3.11272,524,902 - 72,532,408 (-)NCBI
UNSW_CanFamBas_1.01272,346,638 - 72,354,211 (-)NCBI
UU_Cfam_GSD_1.01272,737,393 - 72,744,967 (-)NCBI
DLL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1199,231 - 211,344 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11198,815 - 211,346 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21280,640 - 291,729 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DLL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11397,928,480 - 97,936,594 (+)NCBI
ChlSab1.1 Ensembl1397,928,634 - 97,936,589 (+)Ensembl
Vero_WHO_p1.0NW_02366604069,934,302 - 69,943,226 (+)NCBI
Dll1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248506,135,214 - 6,142,975 (-)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005342496 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_005342496   ⟹   XP_005342553
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404946151,369,680 - 151,377,618 (+)NCBI
SpeTri2.0NW_004937098212,704 - 220,589 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005342553 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3290634 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005342553   ⟸   XM_005342496
- UniProtKB: I3N1H9 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
DSL   EGF-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000026359 ENTREZGENE
Ensembl Protein ENSSTOP00000018225 ENTREZGENE
NCBI Gene Dll1 ENTREZGENE
UniProt I3N1H9 ENTREZGENE