Hoxa7 (homeobox A7) - Rat Genome Database

Name: Hoxa7
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Hoxa7 (homeobox A7) Ictidomys tridecemlineatus

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Symbol:

Hoxa7

Name:

homeobox A7

RGD ID:

12677372

Description:

ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN anterior/posterior pattern specification (ortholog); embryonic skeletal system morphogenesis (ortholog); negative regulation of keratinocyte differentiation (ortholog); ASSOCIATED WITH pleomorphic xanthoastrocytoma (ortholog); FOUND IN nuclear membrane (inferred); nucleoplasm (inferred); nucleus (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

homeobox protein Hox-A7

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	HOXA7 (homeobox A7)	NCBI	Ortholog
Mus musculus (house mouse):	Hoxa7 (homeobox A7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Hoxa7 (homeobox A7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Hoxa7 (homeobox A7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	HOXA7 (homeobox A7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	HOXA7 (homeobox A7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LOC103226327 (homeobox protein Hox-A6)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Hoxa7 (homeobox A7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	84,569,675 - 84,572,760 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936478	3,782,482 - 3,784,361 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936478	3,782,476 - 3,784,361 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

pleomorphic xanthoastrocytoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

angiogenesis (IEA)

anterior/posterior pattern specification (IEA,ISO)

embryonic skeletal system development (IEA)

embryonic skeletal system morphogenesis (IEA,ISO)

negative regulation of cell-matrix adhesion (IEA)

negative regulation of DNA-templated transcription (IEA)

negative regulation of keratinocyte differentiation (IEA,ISO)

negative regulation of leukocyte migration (IEA)

negative regulation of monocyte differentiation (IEA)

negative regulation of transcription by RNA polymerase II (IEA,ISO)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

regulation of DNA-templated transcription (IEA,ISO)

regulation of transcription by RNA polymerase II (IEA)

stem cell differentiation (IEA,ISO)

Cellular Component

nuclear membrane (IEA)

nucleoplasm (IEA)

nucleus (IEA)

Molecular Function

DNA binding (IEA)

DNA-binding transcription activator activity, RNA polymerase II-specific (IEA)

DNA-binding transcription factor activity (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IEA)

DNA-binding transcription factor binding (IEA)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IEA)

sequence-specific DNA binding (IEA)

sequence-specific double-stranded DNA binding (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Hoxa7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	84,569,675 - 84,572,760 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936478	3,782,482 - 3,784,361 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936478	3,782,476 - 3,784,361 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

HOXA7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	27,153,716 - 27,156,675 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	27,153,716 - 27,157,936 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	27,193,335 - 27,196,294 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	27,159,860 - 27,162,821 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	7	26,967,529 - 26,969,536	NCBI
Celera	7	27,182,274 - 27,185,235 (-)	NCBI		Celera
Cytogenetic Map	7	p15.2	NCBI
HuRef	7	27,073,747 - 27,076,708 (-)	NCBI		HuRef
CHM1_1	7	27,193,051 - 27,196,012 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	7	27,289,707 - 27,297,085 (-)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	27,244,510 - 27,247,471 (-)	NCBI

Hoxa7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	52,191,471 - 52,198,757 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	52,191,471 - 52,198,834 (-)	Ensembl		GRCm39 Ensembl
GRCm38	6	52,215,623 - 52,218,573 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	52,214,491 - 52,221,854 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	52,165,622 - 52,168,572 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	52,145,206 - 52,148,156 (-)	NCBI		MGSCv36	mm8
Celera	6	52,737,261 - 52,740,211 (-)	NCBI		Celera
Cytogenetic Map	6	B3	NCBI
cM Map	6	25.4	NCBI

Hoxa7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	82,646,342 - 82,652,449 (-)	NCBI		GRCr8
mRatBN7.2	4	81,315,730 - 81,317,629 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	81,314,625 - 81,317,659 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	86,537,519 - 86,539,409 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	82,312,905 - 82,314,795 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	80,740,052 - 80,741,942 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	82,184,299 - 82,187,890 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	82,183,196 - 82,186,190 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	146,851,130 - 146,854,687 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	80,515,622 - 80,517,521 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	4	76,206,442 - 76,208,341 (-)	NCBI		Celera
Cytogenetic Map	4	q24	NCBI

Hoxa7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955410	28,847,893 - 28,851,062 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955410	28,848,029 - 28,851,069 (-)	NCBI	ChiLan1.0	ChiLan1.0

HOXA7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	31,982,932 - 31,987,550 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	80,308,768 - 80,310,610 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	27,799,317 - 27,802,492 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	27,397,888 - 27,402,142 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	27,396,898 - 27,402,142 (-)	Ensembl	panpan1.1		panPan2

HOXA7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	18	45,417,203 - 45,419,101 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	18	45,417,137 - 45,419,113 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	18	50,047,209 - 50,052,308 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LOC103226327
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	31,208,988 - 31,215,227 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	21	31,221,230 - 31,223,278 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
ChlSab1.1 Ensembl	21	31,212,209 - 31,215,392 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666042	73,509,101 - 73,524,828 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Hoxa7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624739	3,448,199 - 3,452,717 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624739	3,448,982 - 3,451,985 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005319143	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040291794	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000177	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000011207 ⟹ ENSSTOP00000010052

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936478	3,782,482 - 3,784,361 (-)	Ensembl

Ensembl Acc Id:

ENSSTOT00000039125 ⟹ ENSSTOP00000026882

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936478	3,783,386 - 3,784,229 (-)	Ensembl

RefSeq Acc Id:

XM_005319143 ⟹ XP_005319200

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	84,569,675 - 84,572,666 (-)	NCBI
SpeTri2.0	NW_004936478	3,782,476 - 3,784,361 (-)	NCBI

Sequence:

show sequence

GTGCTGCCGCGAGCTCCGTCCAAAAGAAAATGGGGTTTGGTGTAAATCTGGGGGTGTAATGTTA
TCATATATCACGCTACCTCGTAAAACCGACACTGAAAGCTGCCGGACAACAAATCACAGGTCAA
AATTATGAGTTCTTCGTATTATGTGAACGCGCTTTTTAGCAAATATACGGCGGGGGCTTCTCTG
TTCCAAAATGCCGAACCTACTTCTTGCTCCTTTGCGCCCAACTCTCAGAGAAGCGGCTACGGGG
CGGGCGCCGGCGCCTTCGCCTCCACGGTACCGGGCTTATACAATGTCAACAGCCCCCTCTATCA
GAGCCCCTTCGCATCGGGCTACGGCCTGGGCGCCGACGCCTACGGCAACCTGCCCTGCGCCTCC
TACGACCAAAACATCCCCGGGCTCTGCAGTGACCTCGCCAAAGGCGCCTGCGACAAGGCAGACG
AGGGCGCGCTGCACGGCCCAGCCGAGGCCAATTTCCGCATCTACCCCTGGATGAGGTCTTCAGG
ACCTGACAGGAAGCGAGGTCGCCAAACCTATACGCGCTACCAGACGCTGGAGCTGGAGAAGGAG
TTCCACTTCAATCGCTACCTGACGCGGCGGCGCCGCATCGAGATCGCCCACGCTCTCTGCCTCA
CTGAGCGCCAGATCAAGATCTGGTTCCAGAACCGCCGCATGAAGTGGAAGAAAGAACATAAGGA
CGAGGGTCCATCAGCCACTGCAGTCTCTGAGGGTGCAGTGCCCTCCGCTGCTTCTGCTGCCGCT
GCCGCGGACAAGGCCGATGAGGAGGAGGAAGATGAAGAGGAGGACGAAGAGGAGGAGGAATGAA
GGGCCACACTGGGGCCCTGGCTGCACTGGACAGTCAGAAAAGCGTCTTTGAGAAACTCACTGGT
TTTATTTACAAAAATGGGGAAAATAAGAAGAAAATGTAAAAAA

hide sequence

RefSeq Acc Id:

XM_040291794 ⟹ XP_040147728

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405118	84,571,203 - 84,572,760 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_005319200	(Get FASTA)	NCBI Sequence Viewer
	XP_040147728	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000010052.3
	ENSSTOP00000026882.1
GenBank Protein	KAG3278049	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005319200 ⟸ XM_005319143
- Peptide Label:	isoform X1
- UniProtKB:	I3MGW3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSSSYYVNALFSKYTAGASLFQNAEPTSCSFAPNSQRSGYGAGAGAFASTVPGLYNVNSPLYQS PFASGYGLGADAYGNLPCASYDQNIPGLCSDLAKGACDKADEGALHGPAEANFRIYPWMRSSGP DRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKDE GPSATAVSEGAVPSAASAAAAADKADEEEEDEEEDEEEEE hide sequence

RefSeq Acc Id:	XP_040147728 ⟸ XM_040291794
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSSTOP00000010052 ⟸ ENSSTOT00000011207

Ensembl Acc Id:

ENSSTOP00000026882 ⟸ ENSSTOT00000039125

Protein Domains

Homeobox

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000011208	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000011207.3	UniProtKB/TrEMBL
	ENSSTOT00000039125.1	UniProtKB/TrEMBL
Gene3D-CATH	Homeodomain-like	UniProtKB/TrEMBL
InterPro	Antp_homeobox	UniProtKB/TrEMBL
	Homeobox-like_sf	UniProtKB/TrEMBL
	Homeobox_antennapedia	UniProtKB/TrEMBL
	Homeobox_Antennapedia_CS	UniProtKB/TrEMBL
	Homeobox_CS	UniProtKB/TrEMBL
	Homeobox_dom	UniProtKB/TrEMBL
	Homeobox_metazoa	UniProtKB/TrEMBL
NCBI Gene	Hoxa7	ENTREZGENE
PANTHER	HOMEOBOX PROTEIN HOX	UniProtKB/TrEMBL
	HOMEOBOX PROTEIN HOX-A7	UniProtKB/TrEMBL
Pfam	Homeodomain	UniProtKB/TrEMBL
PRINTS	ANTENNAPEDIA	UniProtKB/TrEMBL
	HOMEOBOX	UniProtKB/TrEMBL
PROSITE	ANTENNAPEDIA	UniProtKB/TrEMBL
	HOMEOBOX_1	UniProtKB/TrEMBL
	HOMEOBOX_2	UniProtKB/TrEMBL
SMART	HOX	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46689	UniProtKB/TrEMBL
UniProt	A0A287CZZ2_ICTTR	UniProtKB/TrEMBL
	I3MGW3	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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