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Gene: Rpe65 (retinoid isomerohydrolase RPE65) Ictidomys tridecemlineatus
Symbol: Rpe65
Name: retinoid isomerohydrolase RPE65
RGD ID: 12677040
Description: ENCODES a protein that exhibits all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity (ortholog); all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity (ortholog); isomerase activity (ortholog); INVOLVED IN camera-type eye development (ortholog); cellular response to electrical stimulus (ortholog); circadian rhythm (ortholog); PARTICIPATES IN altered retinoid cycle metabolic pathway; retinitis pigmentosa pathway; retinoid cycle metabolic pathway; ASSOCIATED WITH adrenocorticotropic hormone deficiency (ortholog); autistic disorder (ortholog); basal cell carcinoma (ortholog); FOUND IN cell body (ortholog); endoplasmic reticulum membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: retinal pigment epithelium-specific protein 65kDa; retinoid isomerohydrolase; RPE65, retinoid isomerohydrolase
Homo sapiens (human) : RPE65 (retinoid isomerohydrolase RPE65)  HGNC  Alliance
Mus musculus (house mouse) : Rpe65 (retinal pigment epithelium 65)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rpe65 (retinoid isomerohydrolase RPE65)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rpe65 (retinoid isomerohydrolase RPE65)
Pan paniscus (bonobo/pygmy chimpanzee) : RPE65 (retinoid isomerohydrolase RPE65)
Canis lupus familiaris (dog) : RPE65 (retinoid isomerohydrolase RPE65)
Sus scrofa (pig) : RPE65 (retinoid isomerohydrolase RPE65)
Chlorocebus sabaeus (African green monkey) : RPE65 (retinoid isomerohydrolase RPE65)
Heterocephalus glaber (naked mole-rat) : Rpe65 (retinoid isomerohydrolase RPE65)
more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
SpeTri2.0NW_0049365913,347,346 - 3,368,062 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene Ontology Annotations
Molecular Pathway Annotations


Comparative Map Data



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Rpe65
Ensembl Gene
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 12677040
Created: 2017-01-27
Species: Ictidomys tridecemlineatus
Last Modified: 2020-08-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.