Syt4 (synaptotagmin 4) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Syt4 (synaptotagmin 4) Ictidomys tridecemlineatus
Analyze
Symbol: Syt4
Name: synaptotagmin 4
RGD ID: 12675656
Description: ENCODES a protein that exhibits calcium-dependent phospholipid binding (ortholog); phosphatidylserine binding (ortholog); phospholipid binding (ortholog); INVOLVED IN negative regulation of calcium ion-dependent exocytosis (ortholog); negative regulation of dense core granule exocytosis (ortholog); negative regulation of neurotransmitter secretion (ortholog); ASSOCIATED WITH intellectual disability (ortholog); melanoma (ortholog); visual epilepsy (ortholog); FOUND IN dense core granule (ortholog); glutamatergic synapse (ortholog); neuron projection terminus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: synaptotagmin-4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494443,708,440 - 43,718,775 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365173,035,521 - 3,047,964 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365173,035,840 - 3,044,065 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Syt4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494443,708,440 - 43,718,775 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365173,035,521 - 3,047,964 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365173,035,840 - 3,044,065 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SYT4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381843,267,892 - 43,277,490 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1843,267,892 - 43,277,535 (-)EnsemblGRCh38hg38GRCh38
GRCh371840,847,857 - 40,857,455 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361839,101,855 - 39,111,342 (-)NCBINCBI36Build 36hg18NCBI36
Build 341839,101,856 - 39,111,342NCBI
Celera1837,656,042 - 37,665,799 (-)NCBICelera
Cytogenetic Map18q12.3NCBI
HuRef1837,706,367 - 37,716,125 (-)NCBIHuRef
CHM1_11840,774,888 - 40,784,646 (-)NCBICHM1_1
T2T-CHM13v2.01843,459,665 - 43,469,261 (-)NCBIT2T-CHM13v2.0
Syt4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391831,570,861 - 31,580,468 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1831,570,861 - 31,580,459 (-)EnsemblGRCm39 Ensembl
GRCm381831,437,808 - 31,447,415 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1831,437,808 - 31,447,406 (-)EnsemblGRCm38mm10GRCm38
MGSCv371831,597,462 - 31,607,069 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361831,580,818 - 31,590,425 (-)NCBIMGSCv36mm8
Celera1831,923,439 - 31,933,127 (-)NCBICelera
Cytogenetic Map18B1NCBI
cM Map1817.75NCBI
Syt4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81823,311,454 - 23,320,863 (-)NCBIGRCr8
mRatBN7.21823,036,973 - 23,046,380 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1823,038,378 - 23,046,332 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1823,165,351 - 23,174,758 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01823,922,462 - 23,931,883 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01823,260,316 - 23,269,724 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01824,172,580 - 24,181,989 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1824,172,587 - 24,182,012 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01823,893,019 - 23,902,428 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41823,805,080 - 23,814,489 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11823,833,130 - 23,841,087 (-)NCBI
Celera1822,798,742 - 22,808,151 (-)NCBICelera
Cytogenetic Map18p12NCBI
Syt4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540229,193,455 - 29,204,975 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540229,195,124 - 29,204,816 (-)NCBIChiLan1.0ChiLan1.0
SYT4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21760,684,036 - 60,693,728 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11846,376,629 - 46,386,310 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01836,540,756 - 36,550,439 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11840,089,938 - 40,099,721 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1840,089,938 - 40,099,721 (-)Ensemblpanpan1.1panPan2
SYT4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1747,555,110 - 47,565,313 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl747,509,852 - 47,563,714 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha746,971,902 - 46,982,069 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0747,511,288 - 47,521,437 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl747,511,232 - 47,521,424 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1747,213,662 - 47,223,814 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0747,249,749 - 47,259,895 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0747,539,197 - 47,549,385 (+)NCBIUU_Cfam_GSD_1.0
SYT4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6127,382,263 - 127,392,164 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16127,382,248 - 127,392,258 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SYT4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11837,595,187 - 37,604,931 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1837,595,035 - 37,606,007 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605012,024,554 - 12,034,291 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Syt4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477917,592,669 - 17,603,403 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477917,593,760 - 17,603,217 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005325559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSSTOT00000009202   ⟹   ENSSTOP00000008253
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365173,035,521 - 3,047,964 (+)Ensembl
RefSeq Acc Id: XM_005325559   ⟹   XP_005325616
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494443,708,440 - 43,718,775 (+)NCBI
SpeTri2.0NW_0049365173,035,840 - 3,044,065 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005325616 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000008253.3
GenBank Protein KAG3293952 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_005325616   ⟸   XM_005325559
- UniProtKB: I3MD43 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSSTOP00000008253   ⟸   ENSSTOT00000009202
Protein Domains
C2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000009215 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000009202.3 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.150 UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  Synaptotagmin UniProtKB/TrEMBL
NCBI Gene Syt4 ENTREZGENE
PANTHER PTHR10024:SF114 UniProtKB/TrEMBL
  SYNAPTOTAGMIN UniProtKB/TrEMBL
Pfam PF00168 UniProtKB/TrEMBL
PRINTS SYNAPTOTAGMN UniProtKB/TrEMBL
PROSITE PS50004 UniProtKB/TrEMBL
SMART SM00239 UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/TrEMBL
UniProt I3MD43 ENTREZGENE, UniProtKB/TrEMBL