Ror1 (receptor tyrosine kinase like orphan receptor 1) - Rat Genome Database

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Gene: Ror1 (receptor tyrosine kinase like orphan receptor 1) Ictidomys tridecemlineatus
Analyze
Symbol: Ror1
Name: receptor tyrosine kinase like orphan receptor 1
RGD ID: 12672806
Description: ENCODES a protein that exhibits ATP binding (inferred); nucleotide binding (inferred); protein kinase activity (inferred); INVOLVED IN astrocyte development (ortholog); ASSOCIATED WITH autosomal recessive nonsyndromic deafness 108 (ortholog); Breast Neoplasms (ortholog); genetic disease (ortholog); FOUND IN cell surface (ortholog); stress fiber (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: inactive tyrosine-protein kinase transmembrane receptor ROR1; tyrosine-protein kinase transmembrane receptor ROR1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505877,012,361 - 77,386,624 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366921,328,195 - 1,699,703 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366921,327,779 - 1,702,350 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ror1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505877,012,361 - 77,386,624 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366921,328,195 - 1,699,703 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366921,327,779 - 1,702,350 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ROR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38163,774,017 - 64,181,498 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl163,774,017 - 64,181,498 (+)EnsemblGRCh38hg38GRCh38
GRCh37164,239,688 - 64,647,181 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36164,012,278 - 64,417,295 (+)NCBINCBI36Build 36hg18NCBI36
Build 34163,951,734 - 64,356,728NCBI
Celera162,529,560 - 62,934,556 (+)NCBICelera
Cytogenetic Map1p31.3NCBI
HuRef162,347,586 - 62,756,081 (+)NCBIHuRef
CHM1_1164,355,431 - 64,762,928 (+)NCBICHM1_1
T2T-CHM13v2.0163,649,841 - 64,057,220 (+)NCBIT2T-CHM13v2.0
Ror1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39499,952,988 - 100,302,003 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl499,952,988 - 100,301,962 (+)EnsemblGRCm39 Ensembl
GRCm384100,095,791 - 100,444,806 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4100,095,791 - 100,444,765 (+)EnsemblGRCm38mm10GRCm38
MGSCv37499,768,396 - 100,115,150 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36499,593,723 - 99,940,477 (+)NCBIMGSCv36mm8
Celera498,440,698 - 98,803,975 (+)NCBICelera
Cytogenetic Map4C6NCBI
cM Map445.71NCBI
Ror1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85119,859,744 - 120,203,573 (+)NCBIGRCr8
mRatBN7.25114,744,311 - 115,088,155 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5114,744,304 - 115,088,155 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5117,300,787 - 117,645,050 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05119,026,114 - 119,370,397 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05119,088,648 - 119,432,748 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05118,892,874 - 119,239,528 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5119,097,715 - 119,241,733 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05122,797,453 - 123,142,158 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45120,746,419 - 121,098,205 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5113,291,894 - 113,634,989 (+)NCBICelera
Cytogenetic Map5q33NCBI
Ror1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542326,028,250 - 26,170,533 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542326,029,122 - 26,274,668 (-)NCBIChiLan1.0ChiLan1.0
ROR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21162,671,934 - 163,080,645 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11161,822,491 - 162,231,248 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0163,030,097 - 63,437,919 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1164,838,657 - 65,326,640 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl164,839,061 - 65,324,036 (+)Ensemblpanpan1.1panPan2
ROR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1546,010,097 - 46,477,882 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl546,013,195 - 46,190,880 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha546,068,820 - 46,544,259 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0546,188,060 - 46,663,533 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl546,187,788 - 46,589,860 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1546,150,427 - 46,625,603 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0546,096,358 - 46,571,532 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0546,354,072 - 46,829,399 (-)NCBIUU_Cfam_GSD_1.0
ROR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6148,315,286 - 148,761,524 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16148,314,575 - 148,834,659 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26136,767,337 - 136,909,420 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ROR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12068,910,736 - 69,318,775 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2068,910,751 - 68,954,618 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603348,147,169 - 48,565,776 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ror1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474230,172,093 - 30,319,067 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474230,172,458 - 30,474,801 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005337717 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000023080   ⟹   ENSSTOP00000023160
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366921,538,012 - 1,699,703 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000035601   ⟹   ENSSTOP00000027249
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366921,328,195 - 1,699,700 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000043092   ⟹   ENSSTOP00000026796
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366921,538,897 - 1,699,703 (+)Ensembl
RefSeq Acc Id: XM_005337717   ⟹   XP_005337774
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505877,012,361 - 77,386,624 (+)NCBI
SpeTri2.0NW_0049366921,327,779 - 1,702,350 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005337774 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000023160.2
  ENSSTOP00000026796.1
  ENSSTOP00000027249.1
GenBank Protein KAG3283316 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005337774   ⟸   XM_005337717
- UniProtKB: A0A287D149 (UniProtKB/TrEMBL),   I3NFL3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000026796   ⟸   ENSSTOT00000043092
RefSeq Acc Id: ENSSTOP00000027249   ⟸   ENSSTOT00000035601
RefSeq Acc Id: ENSSTOP00000023160   ⟸   ENSSTOT00000023080
Protein Domains
FZ   Ig-like   Kringle   Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000022807 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000023080.2 UniProtKB/TrEMBL
  ENSSTOT00000035601.1 UniProtKB/TrEMBL
  ENSSTOT00000043092.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.2000.10 UniProtKB/TrEMBL
  2.40.20.10 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Frizzled_dom UniProtKB/TrEMBL
  Frizzled_dom_sf UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Kringle UniProtKB/TrEMBL
  Kringle-like UniProtKB/TrEMBL
  Kringle_CS UniProtKB/TrEMBL
  Kringle_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/TrEMBL
  Tyr_kinase_rcpt_ROR UniProtKB/TrEMBL
NCBI Gene Ror1 ENTREZGENE
PANTHER INACTIVE TYROSINE-PROTEIN KINASE TRANSMEMBRANE RECEPTOR ROR1 UniProtKB/TrEMBL
  TYROSINE-PROTEIN KINASE RECEPTOR UniProtKB/TrEMBL
Pfam I-set UniProtKB/TrEMBL
  Kringle UniProtKB/TrEMBL
  PF01392 UniProtKB/TrEMBL
  PK_Tyr_Ser-Thr UniProtKB/TrEMBL
PIRSF TyrPK_TMrec_ROR UniProtKB/TrEMBL
PRINTS KRINGLE UniProtKB/TrEMBL
  TYRKINASE UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
  KRINGLE_1 UniProtKB/TrEMBL
  KRINGLE_2 UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/TrEMBL
  PS50038 UniProtKB/TrEMBL
SMART IGc2 UniProtKB/TrEMBL
  SM00130 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
  SSF57440 UniProtKB/TrEMBL
UniProt A0A287CZU9_ICTTR UniProtKB/TrEMBL
  A0A287D149 ENTREZGENE, UniProtKB/TrEMBL
  I3NFL3 ENTREZGENE, UniProtKB/TrEMBL