Agrn (agrin) - Rat Genome Database

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Gene: Agrn (agrin) Ictidomys tridecemlineatus
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Symbol: Agrn
Name: agrin
RGD ID: 12672181
Description: ENCODES a protein that exhibits acetylcholine receptor regulator activity (ortholog); ATPase inhibitor activity (ortholog); BMP binding (ortholog); INVOLVED IN chemical synaptic transmission (ortholog); negative regulation of P-type sodium:potassium-exchanging transporter activity (ortholog); negative regulation of sodium ion export across plasma membrane (ortholog); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; ASSOCIATED WITH acute myeloid leukemia (ortholog); congenital myasthenic syndrome (ortholog); congenital myasthenic syndrome 8 (ortholog); FOUND IN axonal growth cone (ortholog); basement membrane (ortholog); cell surface (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505827,426,638 - 27,455,302 (+)NCBI
SpeTri2.0NW_0049367372,010,647 - 2,041,401 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
Agrn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505827,426,638 - 27,455,302 (+)NCBI
SpeTri2.0NW_0049367372,010,647 - 2,041,401 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AGRN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl11,020,120 - 1,056,118 (+)EnsemblGRCh38hg38GRCh38
GRCh3811,020,102 - 1,056,119 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371955,500 - 991,496 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361945,366 - 981,355 (+)NCBINCBI36hg18NCBI36
Celera11,597,136 - 1,631,462 (-)NCBI
Cytogenetic Map1p36.33NCBI
HuRef1226,888 - 263,237 (+)NCBIHuRef
CHM1_11942,522 - 978,540 (+)NCBICHM1_1
Agrn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394156,249,747 - 156,281,997 (-)NCBIGRCm39mm39
GRCm39 Ensembl4156,249,747 - 156,281,945 (-)Ensembl
GRCm384156,165,290 - 156,197,533 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4156,165,290 - 156,197,488 (-)EnsemblGRCm38mm10GRCm38
MGSCv374155,539,399 - 155,559,244 (-)NCBIGRCm37mm9NCBIm37
MGSCv364155,009,090 - 155,028,935 (-)NCBImm8
Celera4158,419,989 - 158,441,614 (-)NCBICelera
Cytogenetic Map4E2NCBI
cM Map488.55NCBI
Agrn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25166,749,306 - 166,782,212 (-)NCBI
Rnor_6.0 Ensembl5173,589,819 - 173,622,645 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.05173,589,910 - 173,622,813 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05177,063,797 - 177,096,674 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45172,999,420 - 173,020,764 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15173,009,918 - 173,031,259 (-)NCBI
Celera5164,949,181 - 164,970,209 (-)NCBICelera
Cytogenetic Map5q36NCBI
Agrn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554869,675,214 - 9,704,991 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554869,674,103 - 9,704,994 (-)NCBIChiLan1.0ChiLan1.0
AGRN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11953,977 - 967,946 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1936,000 - 966,808 (+)Ensemblpanpan1.1panPan2
AGRN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1556,239,621 - 56,273,679 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl556,239,701 - 56,272,745 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha556,317,660 - 56,351,511 (+)NCBI
ROS_Cfam_1.0556,443,168 - 56,477,026 (+)NCBI
UMICH_Zoey_3.1556,434,207 - 56,468,062 (+)NCBI
UNSW_CanFamBas_1.0556,326,114 - 56,359,961 (+)NCBI
UU_Cfam_GSD_1.0556,716,182 - 56,750,025 (+)NCBI
AGRN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl663,365,983 - 63,398,311 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1663,366,017 - 63,398,311 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2657,851,241 - 57,880,816 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AGRN
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120130,383,226 - 130,416,926 (-)NCBI
ChlSab1.1 Ensembl20130,383,220 - 130,416,933 (-)Ensembl
Agrn
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248188,475,453 - 8,508,818 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005339270   ⟹   XP_005339327
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505827,436,165 - 27,455,302 (+)NCBI
SpeTri2.0NW_0049367372,010,647 - 2,029,757 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005339271   ⟹   XP_005339328
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505827,426,638 - 27,455,302 (+)NCBI
SpeTri2.0NW_0049367372,010,647 - 2,041,401 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021735915   ⟹   XP_021591590
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505827,436,165 - 27,455,302 (+)NCBI
SpeTri2.0NW_0049367372,010,647 - 2,029,994 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021735916   ⟹   XP_021591591
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505827,436,165 - 27,455,302 (+)NCBI
SpeTri2.0NW_0049367372,010,647 - 2,029,757 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021735917   ⟹   XP_021591592
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505827,436,165 - 27,455,302 (+)NCBI
SpeTri2.0NW_0049367372,010,647 - 2,029,994 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021735918   ⟹   XP_021591593
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505827,436,165 - 27,455,302 (+)NCBI
SpeTri2.0NW_0049367372,010,647 - 2,029,994 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021735919   ⟹   XP_021591594
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505827,436,165 - 27,455,302 (+)NCBI
SpeTri2.0NW_0049367372,010,647 - 2,029,994 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021735920   ⟹   XP_021591595
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505827,436,165 - 27,455,302 (+)NCBI
SpeTri2.0NW_0049367372,010,647 - 2,029,991 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021735921   ⟹   XP_021591596
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_0049367372,010,647 - 2,029,991 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021735922   ⟹   XP_021591597
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505827,436,165 - 27,455,302 (+)NCBI
SpeTri2.0NW_0049367372,010,647 - 2,029,990 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040287731   ⟹   XP_040143665
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505827,436,433 - 27,455,302 (+)NCBI
Reference Sequences
RefSeq Acc Id: XP_005339328   ⟸   XM_005339271
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: XP_005339327   ⟸   XM_005339270
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_021591592   ⟸   XM_021735917
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_021591593   ⟸   XM_021735918
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_021591594   ⟸   XM_021735919
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_021591590   ⟸   XM_021735915
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_021591596   ⟸   XM_021735921
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_021591595   ⟸   XM_021735920
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_021591597   ⟸   XM_021735922
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_021591591   ⟸   XM_021735916
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_040143665   ⟸   XM_040287731
- Peptide Label: isoform X7
Protein Domains
EGF-like   Kazal-like   LAM_G_DOMAIN   Laminin EGF-like   NtA   SEA


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000015318 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000013734 ENTREZGENE, UniProtKB/TrEMBL
  ENSSTOP00000029835 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000015328 UniProtKB/TrEMBL
  ENSSTOT00000034585 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.120 UniProtKB/TrEMBL
  3.30.70.960 UniProtKB/TrEMBL
InterPro ConA-like_dom_sf UniProtKB/TrEMBL
  EGF-like_Ca-bd_dom UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  FacI_MAC UniProtKB/TrEMBL
  Fol_N UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
  Kazal_dom UniProtKB/TrEMBL
  Kazal_dom_sf UniProtKB/TrEMBL
  Laminin_EGF UniProtKB/TrEMBL
  Laminin_G UniProtKB/TrEMBL
  NtA_dom UniProtKB/TrEMBL
  SEA_dom UniProtKB/TrEMBL
  SEA_dom_sf UniProtKB/TrEMBL
  TIMP-like_OB-fold UniProtKB/TrEMBL
NCBI Gene Agrn ENTREZGENE
Pfam EGF UniProtKB/TrEMBL
  Kazal_1 UniProtKB/TrEMBL
  Kazal_2 UniProtKB/TrEMBL
  Laminin_EGF UniProtKB/TrEMBL
  Laminin_G_1 UniProtKB/TrEMBL
  NtA UniProtKB/TrEMBL
  SEA UniProtKB/TrEMBL
PROSITE EGF_1 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_LAM_1 UniProtKB/TrEMBL
  EGF_LAM_2 UniProtKB/TrEMBL
  KAZAL_2 UniProtKB/TrEMBL
  LAM_G_DOMAIN UniProtKB/TrEMBL
  NTA UniProtKB/TrEMBL
  SEA UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  EGF_Lam UniProtKB/TrEMBL
  FIMAC UniProtKB/TrEMBL
  FOLN UniProtKB/TrEMBL
  KAZAL UniProtKB/TrEMBL
  LamG UniProtKB/TrEMBL
  SEA UniProtKB/TrEMBL
Superfamily-SCOP SSF100895 UniProtKB/TrEMBL
  SSF49899 UniProtKB/TrEMBL
  SSF50242 UniProtKB/TrEMBL
  SSF57184 UniProtKB/TrEMBL
  SSF82671 UniProtKB/TrEMBL
UniProt A0A287D8F4_ICTTR UniProtKB/TrEMBL
  I3MPK1_ICTTR UniProtKB/TrEMBL