Grin3b (glutamate ionotropic receptor NMDA type subunit 3B) - Rat Genome Database

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Gene: Grin3b (glutamate ionotropic receptor NMDA type subunit 3B) Ictidomys tridecemlineatus
Analyze
Symbol: Grin3b
Name: glutamate ionotropic receptor NMDA type subunit 3B
RGD ID: 12671995
Description: ENCODES a protein that exhibits calcium channel activity (ortholog); glycine binding (ortholog); monoatomic cation channel activity (ortholog); INVOLVED IN cellular response to glycine (ortholog); ionotropic glutamate receptor signaling pathway (ortholog); PARTICIPATES IN excitatory synaptic transmission pathway; ASSOCIATED WITH cerebral creatine deficiency syndrome (ortholog); cyclic hematopoiesis (ortholog); genetic disease (ortholog); FOUND IN hippocampal mossy fiber to CA3 synapse (ortholog); NMDA selective glutamate receptor complex (ortholog); postsynaptic density membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: glutamate ionotropic receptor NMDA type subunit 3B, transcript variant X1; glutamate ionotropic receptor NMDA type subunit 3B, transcript variant X2; glutamate ionotropic receptor NMDA type subunit 3B, transcript variant X3; glutamate receptor ionotropic, NMDA 3B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118217,394,254 - 217,401,759 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936588433,261 - 444,237 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936588433,544 - 440,534 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Grin3b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118217,394,254 - 217,401,759 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936588433,261 - 444,237 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936588433,544 - 440,534 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GRIN3B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38191,000,419 - 1,009,732 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl191,000,419 - 1,009,732 (+)EnsemblGRCh38hg38GRCh38
GRCh37191,000,418 - 1,009,731 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3619951,437 - 960,723 (+)NCBINCBI36Build 36hg18NCBI36
Celera19932,775 - 942,061 (+)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef19773,711 - 783,359 (+)NCBIHuRef
CHM1_119999,547 - 1,008,877 (+)NCBICHM1_1
T2T-CHM13v2.019963,087 - 972,401 (+)NCBIT2T-CHM13v2.0
Grin3b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391079,806,227 - 79,813,024 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1079,806,549 - 79,813,024 (+)EnsemblGRCm39 Ensembl
GRCm381079,970,397 - 79,977,190 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1079,970,715 - 79,977,190 (+)EnsemblGRCm38mm10GRCm38
MGSCv371079,433,469 - 79,439,935 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361079,373,853 - 79,380,319 (+)NCBIMGSCv36mm8
Celera1080,985,531 - 80,991,997 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Grin3b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8710,381,495 - 10,387,817 (-)NCBIGRCr8
mRatBN7.279,730,861 - 9,737,183 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl79,730,862 - 9,737,183 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx712,613,161 - 12,619,488 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0714,488,483 - 14,494,810 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0712,349,681 - 12,356,006 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0712,764,993 - 12,771,310 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl712,764,993 - 12,771,310 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0712,934,715 - 12,941,032 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4711,243,973 - 11,250,311 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1711,243,973 - 11,250,304 (-)NCBI
Celera77,906,482 - 7,912,799 (-)NCBICelera
Cytogenetic Map7q11NCBI
Grin3b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554956,859,909 - 6,866,306 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554956,859,909 - 6,866,297 (-)NCBIChiLan1.0ChiLan1.0
GRIN3B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2205,330,379 - 5,339,749 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1194,569,789 - 4,579,054 (+)NCBINHGRI_mPanPan1
PanPan1.1 Ensembl19975,872 - 982,757 (+)Ensemblpanpan1.1panPan2
GRIN3B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12057,703,569 - 57,710,119 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2057,505,626 - 57,512,392 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02058,445,553 - 58,452,550 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2058,445,603 - 58,452,334 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12057,500,871 - 57,509,457 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02057,980,403 - 57,987,181 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02058,183,413 - 58,190,220 (-)NCBIUU_Cfam_GSD_1.0
GRIN3B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl277,401,368 - 77,412,136 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1277,402,191 - 77,411,878 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2277,585,744 - 77,595,456 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GRIN3B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.16756,257 - 766,175 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl6756,618 - 766,048 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660818,153,737 - 8,163,435 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Grin3b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248287,614,672 - 7,622,111 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248287,614,656 - 7,622,111 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000006930   ⟹   ENSSTOP00000006193
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936588433,637 - 440,396 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000042625   ⟹   ENSSTOP00000024728
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936588433,261 - 444,237 (+)Ensembl
RefSeq Acc Id: XM_005331950   ⟹   XP_005332007
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118217,394,254 - 217,401,753 (-)NCBI
SpeTri2.0NW_004936588433,546 - 440,534 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040290793   ⟹   XP_040146727
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118217,394,254 - 217,401,759 (-)NCBI
Protein Sequences
Protein RefSeqs XP_005332007 (Get FASTA)   NCBI Sequence Viewer  
  XP_040146727 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000006193.3
  ENSSTOP00000024728.1
GenBank Protein KAG3280863 (Get FASTA)   NCBI Sequence Viewer  
  KAG3280864 (Get FASTA)   NCBI Sequence Viewer  
  KAG3280865 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005332007   ⟸   XM_005331950
- Peptide Label: isoform X1
- UniProtKB: A0A287CTX7 (UniProtKB/TrEMBL),   I3M8S8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040146727   ⟸   XM_040290793
- Peptide Label: isoform X2
- UniProtKB: I3M8S8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000024728   ⟸   ENSSTOT00000042625
RefSeq Acc Id: ENSSTOP00000006193   ⟸   ENSSTOT00000006930
Protein Domains
Ionotropic glutamate receptor C-terminal   Ionotropic glutamate receptor L-glutamate and


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000006913 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000006930.3 UniProtKB/TrEMBL
  ENSSTOT00000042625.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.2300 UniProtKB/TrEMBL
  Periplasmic binding protein-like II UniProtKB/TrEMBL
InterPro Glu/Gly-bd UniProtKB/TrEMBL
  Iono_rcpt_met UniProtKB/TrEMBL
  Ionotropic_Glu_rcpt UniProtKB/TrEMBL
  Iontro_rcpt UniProtKB/TrEMBL
  Peripla_BP_I UniProtKB/TrEMBL
  Solute-binding_3/MltF_N UniProtKB/TrEMBL
NCBI Gene Grin3b ENTREZGENE
PANTHER GLUTAMATE RECEPTOR IONOTROPIC, NMDA 3B UniProtKB/TrEMBL
  IONOTROPIC GLUTAMATE RECEPTOR UniProtKB/TrEMBL
Pfam Lig_chan UniProtKB/TrEMBL
  Lig_chan-Glu_bd UniProtKB/TrEMBL
  SBP_bac_3 UniProtKB/TrEMBL
PRINTS NMDARECEPTOR UniProtKB/TrEMBL
SMART Lig_chan-Glu_bd UniProtKB/TrEMBL
  PBPe UniProtKB/TrEMBL
Superfamily-SCOP Periplasmic binding protein-like II UniProtKB/TrEMBL
  SSF53822 UniProtKB/TrEMBL
UniProt A0A287CTX7 ENTREZGENE, UniProtKB/TrEMBL
  I3M8S8 ENTREZGENE, UniProtKB/TrEMBL