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Gene: LOC101966280 (sodium/potassium-transporting ATPase subunit alpha-4) Ictidomys tridecemlineatus

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Symbol:

LOC101966280 (Ensembl: ATP1A4)

Name:

sodium/potassium-transporting ATPase subunit alpha-4 (Ensembl:ATPase Na+/K+ transporting subunit alpha 4)

RGD ID:

12671134

Description:

ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ATPase-coupled monoatomic cation transmembrane transporter activity (inferred); INVOLVED IN establishment of localization in cell (ortholog); fertilization (ortholog); flagellated sperm motility (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; alfentanil pharmacodynamics pathway; ASSOCIATED WITH anthracosis (ortholog); autism spectrum disorder (ortholog); autoimmune interstitial lung, joint, and kidney disease (ortholog); FOUND IN cell projection (inferred); membrane (inferred); photoreceptor cell cilium (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

Atp1a4; ATPase Na+/K+ transporting subunit alpha 4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	6,275,960 - 6,308,838 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936740	445,952 - 478,532 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936740	445,952 - 478,580 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

anthracosis (ISO)

autism spectrum disorder (ISO)

autoimmune interstitial lung, joint, and kidney disease (ISO)

familial hemiplegic migraine (ISO)

gastrointestinal stromal tumor (ISO)

parathyroid carcinoma (ISO)

peroxisome biogenesis disorder 12A (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

establishment of localization in cell (IEA,ISO)

establishment or maintenance of transmembrane electrochemical gradient (IEA)

fertilization (IEA,ISO)

flagellated sperm motility (IEA,ISO)

intracellular potassium ion homeostasis (IEA)

intracellular sodium ion homeostasis (IEA)

potassium ion import across plasma membrane (IEA)

potassium ion transmembrane transport (IEA)

potassium ion transport (IEA)

proton transmembrane transport (IEA)

regulation of cellular pH (IEA,ISO)

regulation of membrane potential (IEA,ISO)

sodium ion export across plasma membrane (IEA)

sodium ion transmembrane transport (IEA)

sodium ion transport (IEA,ISO)

spermatogenesis (IEA,ISO)

Cellular Component

cell projection (IEA)

membrane (IEA)

photoreceptor cell cilium (IEA)

plasma membrane (IEA)

rod photoreceptor outer segment (IEA)

sodium:potassium-exchanging ATPase complex (IEA)

sperm midpiece (IEA)

Molecular Function

ATP binding (IEA)

ATP hydrolysis activity (IEA)

ATPase-coupled monoatomic cation transmembrane transporter activity (IEA)

metal ion binding (IEA)

P-type potassium transmembrane transporter activity (IEA)

P-type sodium:potassium-exchanging transporter activity (IEA)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

acebutolol pharmacodynamics pathway (ISO)

adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway (ISO)

alfentanil pharmacodynamics pathway (ISO)

amiloride pharmacodynamics pathway (ISO)

amiodarone pharmacodynamics pathway (ISO)

amlodipine pharmacodynamics pathway (ISO)

atenolol pharmacodynamics pathway (ISO)

bendroflumethiazide pharmacodynamics pathway (ISO)

betaxolol pharmacodynamics pathway (ISO)

bisoprolol pharmacodynamics pathway (ISO)

bumetanide pharmacodynamics pathway (ISO)

bupivacaine pharmacodynamics pathway (ISO)

bupranolol drug pathway (ISO)

bupranolol pharmacodynamics pathway (ISO)

buprenorphine pharmacodynamics pathway (ISO)

carvedilol pharmacodynamics pathway (ISO)

chloroprocaine pharmacodynamics pathway (ISO)

chlorothiazide pharmacodynamics pathway (ISO)

chlorthalidone pharmacodynamics pathway (ISO)

citalopram pharmacodynamics pathway (ISO)

cocaine pharmacodynamics pathway (ISO)

codeine and morphine pharmacodynamics pathway (ISO)

cystinuria pathway (ISO)

desipramine pharmacodynamics pathway (ISO)

diltiazem pharmacodynamics pathway (ISO)

diphenoxylate pharmacodynamics pathway (ISO)

disopyramide pharmacodynamics pathway (ISO)

dobutamine pharmacodynamics pathway (ISO)

eplerenone pharmacodynamics pathway (ISO)

escitalopram pharmacodynamics pathway (ISO)

esmolol pharmacodynamics pathway (ISO)

etacrynic acid pharmacodynamics pathway (ISO)

ethylmorphine pharmacodynamics pathway (ISO)

fentanyl pharmacodynamics pathway (ISO)

flecainde pharmacodynamics pathway (ISO)

fluoxetine pharmacodynamics pathway (ISO)

fosphenytoin pharmacodynamics pathway (ISO)

furosemide pharmacodynamics pathway (ISO)

Hartnup disease pathway (ISO)

heroin pharmacodynamics pathway (ISO)

hydrochlorothiazide pharmacodynamics pathway (ISO)

hydrocodone pharmacodynamics pathway (ISO)

hydroflumethiazide pharmacodynamics pathway (ISO)

hydromorphone pharmacodynamics pathway (ISO)

ibutilide pharmacodynamics pathway (ISO)

iminoglycinuria pathway (ISO)

imipramine pharmacodynamics pathway (ISO)

isoprenaline pharmacodynamics pathway (ISO)

isradipine pharmacodynamics pathway (ISO)

lactose degradation pathway (ISO)

levacetylmethadol pharmacodynamics pathway (ISO)

levobunolol pharmacodynamics pathway (ISO)

levobupivacaine phgarmacodynamics pathway (ISO)

levorphanol pharmacodynamics pathway (ISO)

lidocaine pharmacodynamics pathway (ISO)

lysinuric protein intolerance pathway (ISO)

mepivacaine pharmacodynamics pathway (ISO)

methadone pharmacodynamics pathway (ISO)

metolazone pharmacodynamics pathway (ISO)

metoprolol pharmacodynamics pathway (ISO)

mexiletine pharmacodynamics pathway (ISO)

nadolol pharmacodynamics pathway (ISO)

nalbuphine pharmacodynamics pathway (ISO)

naloxone pharmacodynamics pathway (ISO)

naltrexone pharmacodynamics pathway (ISO)

nebivolol pharmacodynamics pathway (ISO)

nicotine pharmacodynamics pathway (ISO)

nifedipine pharmacodynamics pathway (ISO)

nimodipine pharmacodynamics pathway (ISO)

nisoldipine pharmacodynamics pathway (ISO)

nitrendipine pharmacodynamics pathway (ISO)

oxybuprocaine pharmacodynamics pathway (ISO)

oxycodone pharmacodynamics pathway (ISO)

oxymorphone pharmacodynamics pathway (ISO)

penbutolol pharmacodynamics pathway (ISO)

pentazocine pharmacodynamics pathway (ISO)

phenytoin pharmacodynamics pathway (ISO)

pindolol pharmacodynamics pathway (ISO)

prilocaine pharmacodynamics pathway (ISO)

procainamide pharmacodynamics pathway (ISO)

procaine pharmacodynamics pathway (ISO)

propranolol pharmacodynamics pathway (ISO)

quinidine pharmacodynamics pathway (ISO)

remifentanil pharmacodynamics pathway (ISO)

ropivacaine pharmacodynamics pathway (ISO)

sotalol pharmacodynamics pathway (ISO)

spironolactone pharmacodynamics pathway (ISO)

timolol pharmacodynamics pathway (ISO)

torasemide pharmacodynamics pathway (ISO)

tramadol pharmacodynamics pathway (ISO)

trehalose degradation pathway (ISO)

triamterene pharmacodynamics pathway (ISO)

trichlormethiazide pharmacodynamics pathway (ISO)

verapamil pharmacodynamics pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

LOC101966280
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	6,275,960 - 6,308,838 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936740	445,952 - 478,532 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936740	445,952 - 478,580 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ATP1A4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	160,151,603 - 160,186,980 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	160,151,586 - 160,186,980 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	160,121,393 - 160,156,770 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	158,387,976 - 158,423,391 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	156,934,435 - 156,969,836	NCBI
Celera	1	133,190,120 - 133,225,532 (+)	NCBI		Celera
Cytogenetic Map	1	q23.2	NCBI
HuRef	1	131,478,471 - 131,513,484 (+)	NCBI		HuRef
CHM1_1	1	161,516,689 - 161,552,120 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	159,288,690 - 159,324,059 (+)	NCBI		T2T-CHM13v2.0

Atp1a4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	172,051,075 - 172,085,991 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	172,051,080 - 172,085,981 (-)	Ensembl		GRCm39 Ensembl
GRCm38	1	172,223,508 - 172,258,424 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	172,223,513 - 172,258,414 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	174,153,639 - 174,188,555 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
Celera	1	175,079,480 - 175,114,351 (-)	NCBI		Celera
Cytogenetic Map	1	H3	NCBI
cM Map	1	79.54	NCBI

Atp1a4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	87,216,139 - 87,252,155 (-)	NCBI		GRCr8
mRatBN7.2	13	84,683,766 - 84,719,790 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	84,683,768 - 84,719,687 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	87,187,089 - 87,223,004 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	88,587,350 - 88,623,276 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	85,772,091 - 85,807,950 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	90,605,792 - 90,642,032 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	90,605,794 - 90,641,772 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	95,126,899 - 95,163,433 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	88,213,848 - 88,249,075 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	88,402,731 - 88,437,959 (-)	NCBI
Celera	13	84,295,133 - 84,329,808 (-)	NCBI		Celera
Cytogenetic Map	13	q24	NCBI

ATP1A4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	89,663,062 - 89,701,813 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	89,403,023 - 89,441,794 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	135,504,929 - 135,540,651 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	139,426,556 - 139,462,393 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	139,426,556 - 139,462,393 (+)	Ensembl	panpan1.1		panPan2

ATP1A4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	3,759,509 - 3,794,106 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	3,759,597 - 3,793,980 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	2,816,977 - 2,852,218 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Atp1a4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624794	1,068,056 - 1,108,303 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013364793	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040287268	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040287269	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000117	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSTOT00000007527 ⟹ ENSSTOP00000006727

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936740	445,952 - 478,532 (-)	Ensembl

RefSeq Acc Id:

XM_013364793 ⟹ XP_013220247

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	6,275,960 - 6,308,838 (+)	NCBI
SpeTri2.0	NW_004936740	445,952 - 478,580 (-)	NCBI

Sequence:

show sequence

CTTCCCCCTCTTCCTGAAAATAACCTGGGGCCACCACCTGCCCGCTCAATGACTCTACTGTCCC
TGCAGGACGACCACAAATTAACCTTGGAAGAGCTGAGTGCCAAGTATTCTGTGGACCTGAACAA
AGGTCTTAGCCCCAAAAAAGCAAAGGAAAACCTGCTTCGAGATGGACCCAACGCAATTACTCCT
CCTGCCACCACTCCAGAATGGGTCAAATTCTGTAAACAGTTGTTTGGCGGCTTCTCTCTCCTGC
TGTGGACTGGGGCCATCCTCTGCTTCTTGGCCTATTGCATTCAGCTCTATGCCCATCAGGAACC
TTCCAAAGATAATCTGTTCCTGGGCATCGTGCTGTCTGTCGTGGTCATCATCACCGGCTGCTTC
TCCTATTACCAGGAGGCCAAGAGCTCAAAGATAATGGAATCGTTTAAGGACATGGTGCCACAGC
AAGCTCTGGTGATTCGAGACGGAGAGAAGATGCAAATTGATGTACAAGACGTGGTGGTGGGAGA
CCTGGTAGAGGTGAAAGGTGGAGACCGAATCCCTGCTGACCTCCGGCTTATCTCTTCACAAGGA
TGTAAGGTGGACAATTCCTCCCTGACTGGAGAGTCAGAGCCCCAATCCCGCTCCCCTGACTTCA
CCCATGAGAACCCTCTGGAGACACGAAATATCTGCTTCTTCTCCACCAACTGTGTCGAAGGAAC
AGCCCAGGGTATTGTGATTGCTACAGGAGACTCCACGGTGATGGGCCGAATCGCCACGCTAACA
TCAGGCCTGGTGGTTGGCAAGACGCCCATCGCTAAGGAGATCGAACACTTCATCCATATTATCA
CGATGGTGGCCATCTTCCTCGGTGTCACTTTCTTTGGGCTCTCGCTTCTCTTGGGCTATGACTG
GCTGGAGGCTGTCATTTTTCTCATTGGCATCATTGTGGCCAATGTGCCTGAGGGGCTGCTGGCC
ACTGTCACTGTGTGCTTGACCTTGACAGCCAAGCGCATGGCGCGGAAAAATTGCCTAGTGAAGA
ACCTGGAGGCGGTAGAGACGCTGGGCTCCACGTCTACCATCTGCTCGGACAAGACGGGCACCCT
CACCCAGAACCGCATGACCGTAGCCCACTTGTGGTTTGATTACAACGTGCATGAGGCTGACACC
AATGAAAGACAGTTTGGGGAAACATTTGCCAAGGACTCTGATACTTGGATTATCTTGGCCCAAA
TCGCGGGCCTCTGCAATCGGGCAGACTTTAAAGCTCATCAAGAAACCCTGCCCATAGCTCAGCG
GGAAACAACAGGGGATGCTTCTGAGTCAGCCCTCCTCAAGTTCATCGAGCAGTCCTACAGCTCC
GTGAAGGAGATGAGAGAGAAGTACCCCAAAGTAGCAGAGATTCCCTTTAATTCTACCAACAAGT
ACCAGTTGTCCATCCACCTTCGGGAGGACAGCTCCCAGGCCCACGTACTGATGATGAAAGGTGC
TCCTGAGAAGATCATGGAGTTGTGCTCTACTTTCTTCCTGAATGGCCAAGAGTACCCAATAGAT
GATGAAATGAGGACTGCTTTCCAAAAGGCCTACTTAGAACTGGGAGGCATGGGGGAACGTGTGC
TGGGGTTCTGCTTCTGCAACCTGCCTAGCAGCTTCTTCAAGGGATTCCAATTTAATACAGATGA
GATAAATTTTCCTATGGACACTTTGTGTTTTGTGGGGCTCATATCCATGATCGACCCTCCCCGG
GCAGCTGTTCCACATGCTGTGAGCAAGTGTCGTAGTTCAGGGATTAAGGTGATCATGGTAACAG
GAGATCATCCCATTACAGCCAAGGCCATTGCCAAGGGTGTGGGCATCATCTCAGAAGGTGCAGA
GACAGCAGAGGACATTGCTGCCCGGCTTAACATCCCTGTCAGCCAGGTGGATACCAGGAACGTC
ACAGCCATAGTGGTCCATGGCGCAGACCTGAAGAACATGAGCTCAGAAGAGCTTGACAGGATCC
TCCAGAACCACCCGGAGATTGTGTTTGCTCGGACCTCCCCTCAGCAGAAGCTCAACATTGTGGA
GGGTTGTCAGAGGCTGGGAGCCATTGTGGCGGTGACAGGTGATGGGGTGAACGACTCCCCTGCG
CTGAAGAAGGCGGACATTGGCATCGCCATGGGCATCACTGGCTCCGACGTCTCTAAGCAGGCGG
CCGACATGATCCTGCTGGACGACAACTTTGCCTCCATCGTCACAGGCGTGGAGGAGGGCCGCCT
CATCTTTGACAACCTGAAGAAATCCATTGCGTACACCCTGACCAGCAACATCCCTGAGATCACC
CCCTTCCTGCTGTTCATCATCCTCAGTATTCCGCTGCCACTAGGGACAATCACCATCCTATGCA
TTGACCTGGGCACTGATATGGTCCCAGCTATCTCCTTGGCTTATGAGACAGCGGAAAGTGACAT
CATGAAGAGGCACCCACGGAACTCGAAGACTGATAATCTGGTGAACCACCGTCTCATTGGCATG
GCTTATGGACAGATTGGGATGATCCAGGCTCTAGCAGGATTCTTCACCTACTTCGTGATCTTGG
CCGAAAATGGCTTTAAACCTTTCGATCTGCTGGGTATCCGCCTGAAATGGGATGATCGCTCCGT
AAATGACCTGGAGGACAGCTATGGACAGCAGTGGACCTACGAGCAGCGCAAGGTGGTGGAGTTC
ACTTGCCAGACGGCCTTCTTCGTCAGCATCGTGATTGTGCAGTGGGCTGACCTCATCATCTGCA
AGACCCGCCGCAACTCCGTCTTCCAGCAGGGCACGAAAAACAAGGTTCTAATATTCGGGATCCT
GGAGGAGACACTCCTGGCGGCTTTTCTGTCCTACACTCCAGGCATGGACGTGGCCCTGCGAATG
TACCCACTCAAGTTGGCCTGGTGGTTCTGCGCCCTCCCCTACAGCATTCTCATCTTCGCCTACG
ACGAGATCAGGAAACTCATCATCCGTCAACAGCCTGGCGGCTGGCTGGAGAGGGAGACGTACTA
CTAA

hide sequence

RefSeq Acc Id:

XM_040287268 ⟹ XP_040143202

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	6,281,415 - 6,308,838 (+)	NCBI

RefSeq Acc Id:

XM_040287269 ⟹ XP_040143203

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	6,287,755 - 6,308,838 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_013220247	(Get FASTA)	NCBI Sequence Viewer
	XP_040143202	(Get FASTA)	NCBI Sequence Viewer
	XP_040143203	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000006727.3
GenBank Protein	KAG3281050	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_013220247 ⟸ XM_013364793
- Peptide Label:	isoform X1
- UniProtKB:	I3M9X2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTLLSLQDDHKLTLEELSAKYSVDLNKGLSPKKAKENLLRDGPNAITPPATTPEWVKFCKQLFG GFSLLLWTGAILCFLAYCIQLYAHQEPSKDNLFLGIVLSVVVIITGCFSYYQEAKSSKIMESFK DMVPQQALVIRDGEKMQIDVQDVVVGDLVEVKGGDRIPADLRLISSQGCKVDNSSLTGESEPQS RSPDFTHENPLETRNICFFSTNCVEGTAQGIVIATGDSTVMGRIATLTSGLVVGKTPIAKEIEH FIHIITMVAIFLGVTFFGLSLLLGYDWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARK NCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHLWFDYNVHEADTNERQFGETFAKDSDTW IILAQIAGLCNRADFKAHQETLPIAQRETTGDASESALLKFIEQSYSSVKEMREKYPKVAEIPF NSTNKYQLSIHLREDSSQAHVLMMKGAPEKIMELCSTFFLNGQEYPIDDEMRTAFQKAYLELGG MGERVLGFCFCNLPSSFFKGFQFNTDEINFPMDTLCFVGLISMIDPPRAAVPHAVSKCRSSGIK VIMVTGDHPITAKAIAKGVGIISEGAETAEDIAARLNIPVSQVDTRNVTAIVVHGADLKNMSSE ELDRILQNHPEIVFARTSPQQKLNIVEGCQRLGAIVAVTGDGVNDSPALKKADIGIAMGITGSD VSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIILSIPLPLGT ITILCIDLGTDMVPAISLAYETAESDIMKRHPRNSKTDNLVNHRLIGMAYGQIGMIQALAGFFT YFVILAENGFKPFDLLGIRLKWDDRSVNDLEDSYGQQWTYEQRKVVEFTCQTAFFVSIVIVQWA DLIICKTRRNSVFQQGTKNKVLIFGILEETLLAAFLSYTPGMDVALRMYPLKLAWWFCALPYSI LIFAYDEIRKLIIRQQPGGWLERETYY hide sequence

RefSeq Acc Id:	XP_040143202 ⟸ XM_040287268
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_040143203 ⟸ XM_040287269
- Peptide Label:	isoform X3

Ensembl Acc Id:

ENSSTOP00000006727 ⟸ ENSSTOT00000007527

Protein Domains

Cation-transporting P-type ATPase N-terminal

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000007516	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000007527.3	UniProtKB/TrEMBL
Gene3D-CATH	3.40.1110.10	UniProtKB/TrEMBL
	3.40.50.1000	UniProtKB/TrEMBL
	Calcium-transporting ATPase, cytoplasmic transduction domain A	UniProtKB/TrEMBL
	Calcium-transporting ATPase, transmembrane domain	UniProtKB/TrEMBL
InterPro	ATPase_P-typ_cation-transptr_C	UniProtKB/TrEMBL
	ATPase_P-typ_cation-transptr_N	UniProtKB/TrEMBL
	ATPase_P-typ_cyto_dom_N	UniProtKB/TrEMBL
	ATPase_P-typ_P_site	UniProtKB/TrEMBL
	ATPase_P-typ_TM_dom_sf	UniProtKB/TrEMBL
	ATPase_P-typ_transduc_dom_A_sf	UniProtKB/TrEMBL
	Cation_transp_ATPase_P-type	UniProtKB/TrEMBL
	HAD-like_sf	UniProtKB/TrEMBL
	HAD_sf	UniProtKB/TrEMBL
	P-type_ATPase_IIC	UniProtKB/TrEMBL
	P_typ_ATPase	UniProtKB/TrEMBL
	P_typ_ATPase_HD_dom	UniProtKB/TrEMBL
NCBI Gene	Atp1a4	ENTREZGENE
PANTHER	SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA	UniProtKB/TrEMBL
	SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-4	UniProtKB/TrEMBL
Pfam	Cation_ATPase	UniProtKB/TrEMBL
	Cation_ATPase_C	UniProtKB/TrEMBL
	Cation_ATPase_N	UniProtKB/TrEMBL
	E1-E2_ATPase	UniProtKB/TrEMBL
	Hydrolase	UniProtKB/TrEMBL
PRINTS	CATATPASE	UniProtKB/TrEMBL
	NAKATPASE	UniProtKB/TrEMBL
PROSITE	ATPASE_E1_E2	UniProtKB/TrEMBL
SMART	Cation_ATPase_N	UniProtKB/TrEMBL
Superfamily-SCOP	SSF56784	UniProtKB/TrEMBL
	SSF81653	UniProtKB/TrEMBL
	SSF81660	UniProtKB/TrEMBL
	SSF81665	UniProtKB/TrEMBL
UniProt	I3M9X2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-26	LOC101966280	sodium/potassium-transporting ATPase subunit alpha-4	Atp1a4	ATPase Na+/K+ transporting subunit alpha 4	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - SMPDB