Kcnj16 (potassium inwardly rectifying channel subfamily J member 16) - Rat Genome Database

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Gene: Kcnj16 (potassium inwardly rectifying channel subfamily J member 16) Ictidomys tridecemlineatus
Analyze
Symbol: Kcnj16
Name: potassium inwardly rectifying channel subfamily J member 16
RGD ID: 12669902
Description: ENCODES a protein that exhibits inward rectifier potassium channel activity (inferred); INVOLVED IN potassium ion transport (ortholog); regulation of pH (ortholog); response to carbon dioxide (ortholog); ASSOCIATED WITH hypokalemia (ortholog); Hypokalemic Tubulopathy and Deafness (ortholog); metabolic acidosis (ortholog); FOUND IN basolateral plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: inward rectifier potassium channel 16; potassium inwardly-rectifying channel, subfamily J, member 16; potassium voltage-gated channel subfamily J member 16
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056029,989,581 - 10,013,038 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366553,488,338 - 3,489,597 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366553,487,071 - 3,489,686 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Kcnj16
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056029,989,581 - 10,013,038 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366553,488,338 - 3,489,597 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366553,487,071 - 3,489,686 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNJ16
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381770,075,225 - 70,135,608 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1770,053,429 - 70,135,608 (+)EnsemblGRCh38hg38GRCh38
GRCh371768,071,366 - 68,131,749 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361765,583,021 - 65,643,344 (+)NCBINCBI36Build 36hg18NCBI36
Build 341765,612,589 - 65,643,339NCBI
Celera1764,643,318 - 64,703,632 (+)NCBICelera
Cytogenetic Map17q24.3NCBI
HuRef1763,457,561 - 63,518,274 (+)NCBIHuRef
CHM1_11768,137,477 - 68,197,868 (+)NCBICHM1_1
T2T-CHM13v2.01770,953,535 - 71,013,930 (+)NCBIT2T-CHM13v2.0
Kcnj16
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911110,858,859 - 110,918,794 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11110,858,859 - 110,918,794 (+)EnsemblGRCm39 Ensembl
GRCm3811110,968,033 - 111,027,968 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11110,968,033 - 111,027,968 (+)EnsemblGRCm38mm10GRCm38
MGSCv3711110,829,347 - 110,889,282 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611110,835,677 - 110,844,058 (+)NCBIMGSCv36mm8
Celera11122,716,155 - 122,778,458 (+)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1175.01NCBI
Kcnj16
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81096,489,329 - 96,520,745 (+)NCBIGRCr8
mRatBN7.21095,990,009 - 96,021,356 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1095,960,725 - 96,021,702 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10101,081,523 - 101,083,303 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010100,544,500 - 100,546,280 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01095,952,661 - 95,954,441 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01099,330,894 - 99,391,551 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1099,388,130 - 99,389,898 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01099,027,026 - 99,087,674 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410100,514,180 - 100,515,949 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110100,528,549 - 100,530,318 (+)NCBI
Celera1094,663,783 - 94,665,552 (+)NCBICelera
Cytogenetic Map10q32.1NCBI
Kcnj16
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554782,775,702 - 2,802,501 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554782,775,702 - 2,833,821 (-)NCBIChiLan1.0ChiLan1.0
KCNJ16
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21986,125,515 - 86,157,672 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11790,946,509 - 90,978,647 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01764,005,085 - 64,065,153 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11769,389,581 - 69,449,593 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1769,411,032 - 69,447,343 (+)Ensemblpanpan1.1panPan2
KCNJ16
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1916,369,312 - 16,441,953 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl916,383,702 - 16,441,953 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha917,274,785 - 17,333,030 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0918,023,819 - 18,096,162 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl918,038,198 - 18,096,041 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1916,982,418 - 17,040,164 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0910,494,745 - 10,552,754 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0910,460,571 - 10,518,835 (-)NCBIUU_Cfam_GSD_1.0
KCNJ16
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1210,393,179 - 10,558,169 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11210,393,172 - 10,538,423 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
KCNJ16
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11651,491,064 - 51,631,037 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1651,493,340 - 51,494,596 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607722,382,841 - 22,554,086 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcnj16
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624801269,533 - 335,535 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624801269,449 - 335,535 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000034291   ⟹   ENSSTOP00000030640
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366553,488,338 - 3,489,597 (-)Ensembl
RefSeq Acc Id: XM_005335990   ⟹   XP_005336047
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244056029,989,581 - 10,013,038 (-)NCBI
SpeTri2.0NW_0049366553,487,071 - 3,489,686 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040268519   ⟹   XP_040124453
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244056029,989,581 - 9,992,540 (-)NCBI
RefSeq Acc Id: XM_040268521   ⟹   XP_040124455
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244056029,989,581 - 9,992,510 (-)NCBI
Protein Sequences
Protein RefSeqs XP_005336047 (Get FASTA)   NCBI Sequence Viewer  
  XP_040124453 (Get FASTA)   NCBI Sequence Viewer  
  XP_040124455 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000030640.1
GenBank Protein KAG3268586 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005336047   ⟸   XM_005335990
- UniProtKB: A0A287DAQ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040124453   ⟸   XM_040268519
- UniProtKB: A0A287DAQ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040124455   ⟸   XM_040268521
- UniProtKB: A0A287DAQ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000030640   ⟸   ENSSTOT00000034291
Protein Domains
Inward rectifier potassium channel C-terminal   Potassium channel inwardly rectifying transmembrane


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000030465 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000034291.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.70 UniProtKB/TrEMBL
  2.60.40.1400 UniProtKB/TrEMBL
InterPro Ig_E-set UniProtKB/TrEMBL
  IRK_C UniProtKB/TrEMBL
  K_chnl_inward-rec_Kir UniProtKB/TrEMBL
  K_chnl_inward-rec_Kir5 UniProtKB/TrEMBL
  K_chnl_inward-rec_Kir_cyto UniProtKB/TrEMBL
  Kir_TM UniProtKB/TrEMBL
NCBI Gene Kcnj16 ENTREZGENE
PANTHER PTHR11767 UniProtKB/TrEMBL
  PTHR11767:SF24 UniProtKB/TrEMBL
Pfam IRK UniProtKB/TrEMBL
  IRK_C UniProtKB/TrEMBL
PIRSF GIRK_kir UniProtKB/TrEMBL
PRINTS KIR5CHANNEL UniProtKB/TrEMBL
  KIRCHANNEL UniProtKB/TrEMBL
Superfamily-SCOP SSF81296 UniProtKB/TrEMBL
  Voltage-gated potassium channels UniProtKB/TrEMBL
UniProt A0A287DAQ5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-07-23 Kcnj16  potassium inwardly rectifying channel subfamily J member 16  Kcnj16  potassium voltage-gated channel subfamily J member 16  Symbol and/or name change 5135510 APPROVED