Ncln (nicalin) - Rat Genome Database

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Gene: Ncln (nicalin) Ictidomys tridecemlineatus
Analyze
Symbol: Ncln
Name: nicalin
RGD ID: 12669741
Description: ENCODES a protein that exhibits ribosome binding (inferred); INVOLVED IN multi-pass transmembrane protein insertion into ER membrane (inferred); protein stabilization (inferred); regulation of protein complex stability (inferred); ASSOCIATED WITH genetic disease (ortholog); Hirschsprung's disease (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN endoplasmic reticulum membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118215,994,392 - 216,008,251 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365881,826,045 - 1,840,411 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365881,826,065 - 1,840,391 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ncln
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118215,994,392 - 216,008,251 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365881,826,045 - 1,840,411 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365881,826,065 - 1,840,391 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NCLN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38193,185,930 - 3,209,575 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl193,185,563 - 3,209,575 (+)EnsemblGRCh38hg38GRCh38
GRCh37193,185,928 - 3,209,573 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36193,136,875 - 3,160,573 (+)NCBINCBI36Build 36hg18NCBI36
Build 34193,136,874 - 3,160,572NCBI
Celera193,122,250 - 3,145,978 (+)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef192,952,961 - 2,976,782 (+)NCBIHuRef
CHM1_1193,184,524 - 3,208,222 (+)NCBICHM1_1
T2T-CHM13v2.0193,160,750 - 3,184,441 (+)NCBIT2T-CHM13v2.0
Ncln
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391081,322,289 - 81,333,178 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1081,322,083 - 81,332,226 (-)EnsemblGRCm39 Ensembl
GRCm381081,486,455 - 81,496,954 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1081,486,249 - 81,496,392 (-)EnsemblGRCm38mm10GRCm38
MGSCv371080,949,204 - 80,959,108 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361080,889,378 - 80,899,485 (-)NCBIMGSCv36mm8
Celera1082,509,842 - 82,519,746 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Ncln
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr878,862,324 - 8,872,699 (+)NCBIGRCr8
mRatBN7.278,211,978 - 8,221,938 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl78,211,996 - 8,221,934 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx711,098,042 - 11,107,974 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0712,973,525 - 12,983,457 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0710,840,645 - 10,850,578 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0711,081,544 - 11,091,583 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl711,081,536 - 11,091,584 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0711,248,733 - 11,258,772 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.479,695,951 - 9,705,989 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.179,695,950 - 9,705,988 (+)NCBI
Celera76,402,537 - 6,412,474 (+)NCBICelera
Cytogenetic Map7q11NCBI
Ncln
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554955,222,808 - 5,238,643 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554955,222,990 - 5,238,644 (-)NCBIChiLan1.0ChiLan1.0
NCLN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2207,581,716 - 7,605,672 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1196,815,021 - 6,838,924 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0192,211,474 - 2,235,691 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1193,166,042 - 3,189,681 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl193,166,042 - 3,189,681 (+)Ensemblpanpan1.1panPan2
NCLN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12056,088,017 - 56,104,723 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2056,088,017 - 56,104,723 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2055,811,878 - 55,828,580 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02056,746,690 - 56,763,396 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2056,745,969 - 56,763,411 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12055,802,155 - 55,818,810 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02056,286,144 - 56,302,913 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02056,484,881 - 56,501,641 (-)NCBIUU_Cfam_GSD_1.0
NCLN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl275,369,955 - 75,390,545 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1275,369,926 - 75,390,609 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2275,891,204 - 75,909,206 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NCLN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.162,948,723 - 2,975,465 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl62,948,212 - 2,975,596 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660815,608,300 - 5,633,124 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ncln
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248286,018,439 - 6,035,446 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248286,018,438 - 6,035,310 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSSTOT00000024044   ⟹   ENSSTOP00000017005
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365881,826,045 - 1,840,411 (+)Ensembl
RefSeq Acc Id: XM_005332014   ⟹   XP_005332071
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118215,994,392 - 216,008,251 (-)NCBI
SpeTri2.0NW_0049365881,826,065 - 1,840,391 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021730869   ⟹   XP_021586544
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118215,994,392 - 216,008,123 (-)NCBI
SpeTri2.0NW_0049365881,826,065 - 1,840,391 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005332071 (Get FASTA)   NCBI Sequence Viewer  
  XP_021586544 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000017005.1
RefSeq Acc Id: XP_005332071   ⟸   XM_005332014
- Peptide Label: isoform X1
- UniProtKB: I3MY10 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021586544   ⟸   XM_021730869
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSSTOP00000017005   ⟸   ENSSTOT00000024044
Protein Domains
Peptidase M28


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000022427 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000024044.2 UniProtKB/TrEMBL
Gene3D-CATH Zn peptidases UniProtKB/TrEMBL
InterPro Nicalin UniProtKB/TrEMBL
  Peptidase_M28 UniProtKB/TrEMBL
NCBI Gene Ncln ENTREZGENE
PANTHER NICALIN UniProtKB/TrEMBL
  PTHR31826 UniProtKB/TrEMBL
Pfam Peptidase_M28 UniProtKB/TrEMBL
PIRSF Nicalin UniProtKB/TrEMBL
Superfamily-SCOP Zn-dependent exopeptidases UniProtKB/TrEMBL
UniProt I3MY10 ENTREZGENE, UniProtKB/TrEMBL