Ltbp4 (latent transforming growth factor beta binding protein 4) - Rat Genome Database

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Gene: Ltbp4 (latent transforming growth factor beta binding protein 4) Ictidomys tridecemlineatus
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Symbol: Ltbp4
Name: latent transforming growth factor beta binding protein 4
RGD ID: 12661961
Description: ENCODES a protein that exhibits transforming growth factor beta binding (ortholog); INVOLVED IN elastic fiber assembly (ortholog); hormone secretion (ortholog); regulation of proteolysis (ortholog); ASSOCIATED WITH autosomal recessive cutis laxa type IC (ortholog); COVID-19 (ortholog); glioblastoma (ortholog); FOUND IN collagen-containing extracellular matrix (ortholog); extracellular matrix (ortholog); microfibril (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: latent-transforming growth factor beta-binding protein 4; LOW QUALITY PROTEIN: latent-transforming growth factor beta-binding protein 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934914,489,689 - 14,517,783 (+)NCBI
SpeTri2.0NW_0049366612,919,444 - 2,945,847 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
Ltbp4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934914,489,689 - 14,517,783 (+)NCBI
SpeTri2.0NW_0049366612,919,444 - 2,945,847 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LTBP4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1940,592,883 - 40,629,818 (+)EnsemblGRCh38hg38GRCh38
GRCh381940,593,166 - 40,629,820 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371941,099,072 - 41,135,725 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361945,790,912 - 45,827,565 (+)NCBINCBI36hg18NCBI36
Build 341945,790,911 - 45,827,562NCBI
Celera1937,898,123 - 37,934,766 (+)NCBI
Cytogenetic Map19q13.2NCBI
HuRef1937,533,157 - 37,570,214 (+)NCBIHuRef
CHM1_11941,098,957 - 41,135,597 (+)NCBICHM1_1
Ltbp4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39727,004,566 - 27,039,142 (-)NCBIGRCm39mm39
GRCm39 Ensembl727,004,561 - 27,037,117 (-)Ensembl
GRCm38727,305,140 - 27,339,720 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl727,305,136 - 27,337,692 (-)EnsemblGRCm38mm10GRCm38
MGSCv37728,090,160 - 28,122,631 (-)NCBIGRCm37mm9NCBIm37
MGSCv36727,013,902 - 27,046,452 (-)NCBImm8
Celera721,881,870 - 21,917,412 (-)NCBICelera
Cytogenetic Map7A3NCBI
Ltbp4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2182,600,136 - 82,634,346 (-)NCBI
Rnor_6.0 Ensembl184,118,046 - 84,150,084 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0184,118,046 - 84,152,095 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0185,328,915 - 85,361,198 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4182,385,953 - 82,418,177 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1182,464,068 - 82,487,843 (-)NCBI
Celera177,011,604 - 77,043,761 (-)NCBICelera
Cytogenetic Map1q21NCBI
Ltbp4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955578686,211 - 712,794 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955578685,960 - 712,809 (-)NCBIChiLan1.0ChiLan1.0
LTBP4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11946,144,485 - 46,181,636 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1946,144,485 - 46,181,636 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01937,637,509 - 37,674,791 (+)NCBIMhudiblu_PPA_v0panPan3
LTBP4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11113,124,109 - 113,152,283 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1113,124,109 - 113,150,442 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1112,526,364 - 112,552,684 (-)NCBI
ROS_Cfam_1.01113,722,679 - 113,749,021 (-)NCBI
UMICH_Zoey_3.11113,282,295 - 113,308,625 (-)NCBI
UNSW_CanFamBas_1.01112,913,954 - 112,940,503 (-)NCBI
UU_Cfam_GSD_1.01113,908,479 - 113,934,829 (-)NCBI
LTBP4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl648,831,014 - 48,861,507 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1648,831,018 - 48,861,503 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2644,591,804 - 44,609,182 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LTBP4
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1635,056,287 - 35,090,544 (+)NCBI
ChlSab1.1 Ensembl635,061,225 - 35,090,542 (+)Ensembl
Ltbp4
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624925543,656 - 572,810 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_021734027   ⟹   XP_021589702
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_0049366612,919,444 - 2,945,847 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040279184   ⟹   XP_040135118
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934914,490,460 - 14,517,783 (+)NCBI
RefSeq Acc Id: XM_040279185   ⟹   XP_040135119
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934914,491,431 - 14,517,783 (+)NCBI
RefSeq Acc Id: XM_040279186   ⟹   XP_040135120
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934914,490,458 - 14,517,783 (+)NCBI
RefSeq Acc Id: XM_040279187   ⟹   XP_040135121
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934914,491,431 - 14,517,783 (+)NCBI
RefSeq Acc Id: XM_040279188   ⟹   XP_040135122
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934914,489,689 - 14,517,783 (+)NCBI
Reference Sequences
RefSeq Acc Id: XP_021589702   ⟸   XM_021734027
- Sequence:
RefSeq Acc Id: XP_040135122   ⟸   XM_040279188
- Peptide Label: isoform X5
RefSeq Acc Id: XP_040135120   ⟸   XM_040279186
- Peptide Label: isoform X3
RefSeq Acc Id: XP_040135118   ⟸   XM_040279184
- Peptide Label: isoform X1
RefSeq Acc Id: XP_040135119   ⟸   XM_040279185
- Peptide Label: isoform X2
RefSeq Acc Id: XP_040135121   ⟸   XM_040279187
- Peptide Label: isoform X4
Protein Domains
EGF-like   TB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000013720 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000012301 UniProtKB/TrEMBL
  ENSSTOP00000024204 UniProtKB/TrEMBL
  ENSSTOP00000027862 UniProtKB/TrEMBL
  ENSSTOP00000031970 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000013728 UniProtKB/TrEMBL
  ENSSTOT00000034272 UniProtKB/TrEMBL
  ENSSTOT00000036407 UniProtKB/TrEMBL
  ENSSTOT00000038905 UniProtKB/TrEMBL
Gene3D-CATH 3.90.290.10 UniProtKB/TrEMBL
InterPro EGF-like_Ca-bd_dom UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/TrEMBL
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/TrEMBL
  EGF_Ca-bd_CS UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
  TB_dom UniProtKB/TrEMBL
  TB_dom_sf UniProtKB/TrEMBL
NCBI Gene Ltbp4 ENTREZGENE
Pfam EGF_CA UniProtKB/TrEMBL
  PF00683 UniProtKB/TrEMBL
PROSITE ASX_HYDROXYL UniProtKB/TrEMBL
  EGF_1 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
  PS51364 UniProtKB/TrEMBL
SMART EGF UniProtKB/TrEMBL
  EGF_CA UniProtKB/TrEMBL
Superfamily-SCOP SSF57184 UniProtKB/TrEMBL
  SSF57581 UniProtKB/TrEMBL
UniProt A0A287CSE4_ICTTR UniProtKB/TrEMBL
  A0A287D2V9_ICTTR UniProtKB/TrEMBL
  A0A287DEI3_ICTTR UniProtKB/TrEMBL
  I3MLK6_ICTTR UniProtKB/TrEMBL