Zer1 (zyg-11 related cell cycle regulator) - Rat Genome Database

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Gene: Zer1 (zyg-11 related cell cycle regulator) Ictidomys tridecemlineatus
Analyze
Symbol: Zer1
Name: zyg-11 related cell cycle regulator
RGD ID: 12661614
Description: INVOLVED IN positive regulation of proteasomal ubiquitin-dependent protein catabolic process (inferred); protein quality control for misfolded or incompletely synthesized proteins (inferred); ASSOCIATED WITH genetic disease (ortholog); primary coenzyme Q10 deficiency 7 (ortholog); FOUND IN Cul2-RING ubiquitin ligase complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein zer-1 homolog; zyg-11 related cell cycle regulator, transcript variant X1; zyg-11 related cell cycle regulator, transcript variant X2; zyg-11 related cell cycle regulator, transcript variant X3; zyg-11 related cell cycle regulator, transcript variant X4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947196,442,211 - 196,471,977 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648716,210,707 - 16,239,660 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648716,210,738 - 16,239,686 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Zer1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947196,442,211 - 196,471,977 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648716,210,707 - 16,239,660 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648716,210,738 - 16,239,686 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZER1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389128,729,786 - 128,772,486 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9128,729,786 - 128,772,414 (-)EnsemblGRCh38hg38GRCh38
GRCh379131,492,065 - 131,534,765 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369130,531,886 - 130,574,019 (-)NCBINCBI36Build 36hg18NCBI36
Build 349128,571,619 - 128,613,752NCBI
Celera9102,142,849 - 102,184,970 (-)NCBICelera
Cytogenetic Map9q34.11NCBI
HuRef9101,101,396 - 101,143,207 (-)NCBIHuRef
CHM1_19131,643,031 - 131,685,172 (-)NCBICHM1_1
T2T-CHM13v2.09140,934,550 - 140,977,266 (-)NCBIT2T-CHM13v2.0
Zer1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39229,987,295 - 30,016,299 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl229,987,295 - 30,014,597 (-)EnsemblGRCm39 Ensembl
GRCm38230,097,283 - 30,126,287 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl230,097,283 - 30,124,585 (-)EnsemblGRCm38mm10GRCm38
MGSCv37229,952,803 - 29,979,974 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36229,919,292 - 29,946,463 (-)NCBIMGSCv36mm8
Celera229,800,800 - 29,827,973 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map221.16NCBI
Zer1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8333,767,520 - 33,806,716 (-)NCBIGRCr8
mRatBN7.2313,369,688 - 13,397,524 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl313,369,688 - 13,397,420 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx316,444,349 - 16,472,223 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0325,029,315 - 25,057,189 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0323,279,906 - 23,307,760 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.038,662,579 - 8,690,486 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl38,662,579 - 8,690,305 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0314,014,737 - 14,042,632 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.439,102,502 - 9,118,423 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.139,102,801 - 9,130,537 (-)NCBI
Celera38,143,197 - 8,170,925 (-)NCBICelera
Cytogenetic Map3p12NCBI
Zer1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555701,138,477 - 1,152,198 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555701,138,477 - 1,153,246 (-)NCBIChiLan1.0ChiLan1.0
ZER1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21110,578,962 - 10,620,951 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1910,581,310 - 10,623,301 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0999,853,433 - 99,895,399 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19128,519,972 - 128,560,107 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9128,519,972 - 128,560,098 (-)Ensemblpanpan1.1panPan2
ZER1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1954,842,607 - 54,873,336 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl954,842,317 - 54,871,717 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha954,038,038 - 54,068,779 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0955,763,691 - 55,794,421 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl955,763,715 - 55,794,421 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1954,524,306 - 54,555,013 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0954,836,989 - 54,867,669 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0954,930,434 - 54,961,182 (+)NCBIUU_Cfam_GSD_1.0
ZER1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1269,090,159 - 269,108,256 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11269,088,696 - 269,121,895 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21303,108,885 - 303,142,096 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ZER1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1129,371,038 - 9,413,127 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl129,371,701 - 9,413,134 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366609653,876 - 98,048 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zer1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247606,247,052 - 6,270,621 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247606,247,016 - 6,270,621 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000009406   ⟹   ENSSTOP00000008437
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493648716,212,235 - 16,229,070 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000038331   ⟹   ENSSTOP00000027091
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493648716,210,707 - 16,239,660 (-)Ensembl
RefSeq Acc Id: XM_005321049   ⟹   XP_005321106
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947196,442,211 - 196,471,158 (-)NCBI
SpeTri2.0NW_00493648716,210,738 - 16,239,686 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013356711   ⟹   XP_013212165
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947196,442,211 - 196,471,158 (-)NCBI
SpeTri2.0NW_00493648716,210,738 - 16,239,679 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013356712   ⟹   XP_013212166
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947196,442,211 - 196,471,159 (-)NCBI
SpeTri2.0NW_00493648716,210,738 - 16,239,679 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013356713   ⟹   XP_013212167
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947196,442,211 - 196,471,153 (-)NCBI
SpeTri2.0NW_00493648716,210,738 - 16,239,679 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040286451   ⟹   XP_040142385
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947196,442,211 - 196,471,977 (-)NCBI
RefSeq Acc Id: XM_040286452   ⟹   XP_040142386
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947196,442,211 - 196,471,159 (-)NCBI
RefSeq Acc Id: XM_040286453   ⟹   XP_040142387
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024404947196,442,211 - 196,471,153 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005321106   ⟸   XM_005321049
- Peptide Label: isoform X4
- UniProtKB: A0A287D0I0 (UniProtKB/TrEMBL),   I3MDH5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013212167   ⟸   XM_013356713
- Peptide Label: isoform X4
- UniProtKB: A0A287D0I0 (UniProtKB/TrEMBL),   I3MDH5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013212166   ⟸   XM_013356712
- Peptide Label: isoform X2
- UniProtKB: I3MDH5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013212165   ⟸   XM_013356711
- Peptide Label: isoform X1
- UniProtKB: I3MDH5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040142385   ⟸   XM_040286451
- Peptide Label: isoform X3
- UniProtKB: I3MDH5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040142386   ⟸   XM_040286452
- Peptide Label: isoform X5
- UniProtKB: I3MDH5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040142387   ⟸   XM_040286453
- Peptide Label: isoform X5
- UniProtKB: I3MDH5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000027091   ⟸   ENSSTOT00000038331
RefSeq Acc Id: ENSSTOP00000008437   ⟸   ENSSTOT00000009406


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000009393 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000009406.3 UniProtKB/TrEMBL
  ENSSTOT00000038331.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Armadillo UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
NCBI Gene Zer1 ENTREZGENE
PANTHER PROTEIN ZER-1 HOMOLOG UniProtKB/TrEMBL
  PTHR12904 UniProtKB/TrEMBL
SMART ARM UniProtKB/TrEMBL
Superfamily-SCOP RNI-like UniProtKB/TrEMBL
  SSF48371 UniProtKB/TrEMBL
UniProt A0A287D0I0 ENTREZGENE, UniProtKB/TrEMBL
  I3MDH5 ENTREZGENE, UniProtKB/TrEMBL