Nipbl (NIPBL cohesin loading factor) - Rat Genome Database

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Gene: Nipbl (NIPBL cohesin loading factor) Ictidomys tridecemlineatus
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Symbol: Nipbl
Name: NIPBL cohesin loading factor
RGD ID: 12660445
Description: ENCODES a protein that exhibits chromatin binding (ortholog); chromo shadow domain binding (ortholog); histone deacetylase binding (ortholog); INVOLVED IN brain development (ortholog); cellular protein localization (ortholog); cellular response to DNA damage stimulus (ortholog); ASSOCIATED WITH bone development disease (ortholog); brachydactyly (ortholog); congenital heart disease (ortholog); FOUND IN chromatin (ortholog); cytosol (ortholog); integrator complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: NIPBL, cohesin loading factor; NIPBL, cohesin loading factor, transcript variant X1; NIPBL, cohesin loading factor, transcript variant X2; NIPBL, cohesin loading factor, transcript variant X3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213226,330,734 - 226,501,147 (+)NCBI
SpeTri2.0NW_0049365184,870,686 - 5,041,099 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

Genomics

Comparative Map Data
Nipbl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213226,330,734 - 226,501,147 (+)NCBI
SpeTri2.0NW_0049365184,870,686 - 5,041,099 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NIPBL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl536,876,769 - 37,066,413 (+)EnsemblGRCh38hg38GRCh38
GRCh38536,876,769 - 37,066,413 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37536,876,871 - 37,066,515 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36536,912,742 - 37,101,678 (+)NCBINCBI36hg18NCBI36
Celera536,763,790 - 36,952,889 (+)NCBI
Cytogenetic Map5p13.2NCBI
HuRef536,829,492 - 37,018,602 (+)NCBIHuRef
CHM1_1536,879,597 - 37,068,738 (+)NCBICHM1_1
Nipbl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39158,319,308 - 8,494,799 (-)NCBIGRCm39mm39
GRCm39 Ensembl158,320,101 - 8,473,947 (-)Ensembl
GRCm38158,289,824 - 8,465,315 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl158,290,617 - 8,444,463 (-)EnsemblGRCm38mm10GRCm38
MGSCv37158,241,225 - 8,394,463 (-)NCBIGRCm37mm9NCBIm37
MGSCv36158,238,440 - 8,391,678 (-)NCBImm8
Celera158,136,258 - 8,289,610 (-)NCBICelera
Cytogenetic Map15A1NCBI
Nipbl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2257,399,443 - 57,586,770 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl257,399,445 - 57,565,899 (-)Ensembl
Rnor_6.0257,508,830 - 57,676,197 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl257,509,428 - 57,600,820 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0278,992,721 - 79,160,884 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4257,908,828 - 58,099,422 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1257,837,538 - 58,006,254 (-)NCBI
Celera253,014,297 - 53,179,686 (-)NCBICelera
Cytogenetic Map2q16NCBI
Nipbl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542621,666,857 - 21,841,515 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542621,666,958 - 21,841,515 (+)NCBIChiLan1.0ChiLan1.0
NIPBL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1578,585,649 - 78,772,665 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl578,585,649 - 78,698,184 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0573,306,527 - 73,491,367 (-)NCBIMhudiblu_PPA_v0panPan3
NIPBL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1471,583,118 - 71,780,986 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl471,583,732 - 71,780,852 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha471,193,245 - 71,390,556 (-)NCBI
ROS_Cfam_1.0472,093,046 - 72,290,807 (-)NCBI
UMICH_Zoey_3.1471,840,270 - 72,037,537 (-)NCBI
UNSW_CanFamBas_1.0471,962,190 - 72,159,916 (-)NCBI
UU_Cfam_GSD_1.0472,493,866 - 72,691,524 (-)NCBI
NIPBL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1622,152,501 - 22,363,847 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11622,152,455 - 22,364,373 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21623,393,877 - 23,512,467 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NIPBL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1435,748,112 - 35,940,075 (+)NCBI
ChlSab1.1 Ensembl435,829,386 - 35,941,271 (+)Ensembl
Vero_WHO_p1.0NW_02366607126,085,896 - 26,277,759 (+)NCBI
Nipbl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475917,899,152 - 18,078,213 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005325630   ⟹   XP_005325687
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213226,330,734 - 226,501,147 (+)NCBI
SpeTri2.0NW_0049365184,870,686 - 5,041,099 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021726576   ⟹   XP_021582251
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213226,388,051 - 226,500,831 (+)NCBI
SpeTri2.0NW_0049365184,870,686 - 4,983,763 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021726577   ⟹   XP_021582252
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213226,330,734 - 226,499,978 (+)NCBI
SpeTri2.0NW_0049365184,871,744 - 5,041,099 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040273065   ⟹   XP_040128999
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024407213226,330,779 - 226,501,147 (+)NCBI
Reference Sequences
RefSeq Acc Id: XP_005325687   ⟸   XM_005325630
- Peptide Label: isoform X1
- UniProtKB: I3MNZ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021582251   ⟸   XM_021726576
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_021582252   ⟸   XM_021726577
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_040128999   ⟸   XM_040273065
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000014981 ENTREZGENE
Ensembl Protein ENSSTOP00000013445 ENTREZGENE
NCBI Gene Nipbl ENTREZGENE
UniProt I3MNZ5 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-29 Nipbl  NIPBL cohesin loading factor    NIPBL, cohesin loading factor  Symbol and/or name change 5135510 APPROVED