Adcyap1 (adenylate cyclase activating polypeptide 1) - Rat Genome Database

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Gene: Adcyap1 (adenylate cyclase activating polypeptide 1) Ictidomys tridecemlineatus
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Symbol: Adcyap1
Name: adenylate cyclase activating polypeptide 1
RGD ID: 12658174
Description: ENCODES a protein that exhibits pituitary adenylate cyclase-activating polypeptide receptor binding (ortholog); INVOLVED IN ATP metabolic process (ortholog); behavioral fear response (ortholog); cellular response to glucocorticoid stimulus (ortholog); ASSOCIATED WITH acute necrotizing pancreatitis (ortholog); autistic disorder (ortholog); Brain Injuries (ortholog); FOUND IN extracellular space (ortholog); terminal bouton (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: adenylate cyclase activating polypeptide 1, transcript variant X1; adenylate cyclase activating polypeptide 1, transcript variant X2; pituitary adenylate cyclase-activating polypeptide
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494464,074,352 - 64,081,544 (+)NCBI
SpeTri2.0NW_0049366723,461,387 - 3,468,053 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adenylate cyclase-activating G protein-coupled receptor signaling pathway  (IEA)
ATP metabolic process  (ISO)
behavioral fear response  (ISO)
cAMP-mediated signaling  (IEA)
cellular response to glucocorticoid stimulus  (ISO)
G protein-coupled receptor signaling pathway  (IEA)
histamine secretion  (ISO)
insulin secretion  (IEA)
negative regulation of acute inflammatory response to antigenic stimulus  (ISO)
negative regulation of acute inflammatory response to non-antigenic stimulus  (ISO)
negative regulation of cell cycle  (IEA,ISO)
negative regulation of glial cell proliferation  (ISO)
negative regulation of GTPase activity  (ISO)
negative regulation of muscle cell apoptotic process  (ISO)
negative regulation of potassium ion transport  (ISO)
neuron projection development  (IEA)
neuropeptide signaling pathway  (IEA)
ovarian follicle development  (ISO)
pituitary gland development  (ISO)
positive regulation of cAMP-mediated signaling  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of chemokine (C-C motif) ligand 5 production  (IEA)
positive regulation of cold-induced thermogenesis  (IEA)
positive regulation of cytosolic calcium ion concentration  (ISO)
positive regulation of ERK1 and ERK2 cascade  (IEA)
positive regulation of gene expression  (IEA,ISO)
positive regulation of growth hormone secretion  (ISO)
positive regulation of GTPase activity  (IEA)
positive regulation of interleukin-6 production  (ISO)
positive regulation of neuron projection development  (ISO)
positive regulation of protein kinase activity  (IEA)
positive regulation of somatostatin secretion  (ISO)
positive regulation of synaptic transmission, glutamatergic  (ISO)
positive regulation of transcription by RNA polymerase II  (IEA)
regulation of G protein-coupled receptor signaling pathway  (IEA)
regulation of oligodendrocyte progenitor proliferation  (ISO)
regulation of postsynaptic membrane potential  (ISO)
regulation of protein localization  (IEA)
regulation of protein phosphorylation  (ISO)
response to ethanol  (ISO)
response to starvation  (ISO)
sensory perception of pain  (ISO)
vasodilation  (ISO)

Cellular Component

References

Genomics

Comparative Map Data
Adcyap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494464,074,352 - 64,081,544 (+)NCBI
SpeTri2.0NW_0049366723,461,387 - 3,468,053 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADCYAP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3818904,411 - 912,172 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl18904,871 - 912,172 (+)EnsemblGRCh38hg38GRCh38
GRCh3718904,872 - 912,173 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3618894,944 - 902,173 (+)NCBINCBI36hg18NCBI36
Build 3418895,386 - 901,050NCBI
Celera18779,552 - 786,777 (+)NCBI
Cytogenetic Map18p11.32NCBI
HuRef18865,131 - 872,354 (+)NCBIHuRef
CHM1_118904,574 - 911,803 (+)NCBICHM1_1
T2T-CHM13v2.0181,059,166 - 1,066,467 (+)NCBI
Adcyap1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391793,505,673 - 93,513,969 (+)NCBIGRCm39mm39
GRCm39 Ensembl1793,506,445 - 93,513,965 (+)Ensembl
GRCm381793,198,245 - 93,206,541 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1793,199,017 - 93,206,537 (+)EnsemblGRCm38mm10GRCm38
MGSCv371793,598,762 - 93,604,831 (+)NCBIGRCm37mm9NCBIm37
MGSCv361793,503,713 - 93,509,782 (+)NCBImm8
Celera1797,603,693 - 97,609,773 (+)NCBICelera
Cytogenetic Map17E5NCBI
Adcyap1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.29113,102,632 - 113,122,500 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl9113,103,718 - 113,109,773 (-)Ensembl
Rnor_6.09121,705,897 - 121,725,736 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl9121,706,979 - 121,725,716 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.09121,155,213 - 121,175,023 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera9110,207,950 - 110,213,150 (-)NCBICelera
Cytogenetic Map9q38NCBI
Adcyap1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554029,091,725 - 9,099,803 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554029,091,927 - 9,099,803 (-)NCBIChiLan1.0ChiLan1.0
ADCYAP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11815,712,078 - 15,718,693 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1815,713,479 - 15,717,749 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01813,414,618 - 13,421,668 (-)NCBIMhudiblu_PPA_v0panPan3
ADCYAP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1767,682,421 - 67,691,035 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha767,135,853 - 67,143,650 (+)NCBI
ROS_Cfam_1.0767,748,641 - 67,756,430 (+)NCBI
ROS_Cfam_1.0 Ensembl767,749,208 - 67,822,788 (+)Ensembl
UMICH_Zoey_3.1767,424,965 - 67,432,752 (+)NCBI
UNSW_CanFamBas_1.0767,436,457 - 67,444,234 (+)NCBI
UU_Cfam_GSD_1.0767,738,672 - 67,746,464 (+)NCBI
ADCYAP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6105,414,631 - 105,422,294 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16105,414,628 - 105,422,294 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2698,531,534 - 98,539,159 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ADCYAP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11860,259,479 - 60,267,302 (+)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605035,058,453 - 35,066,176 (+)NCBIVero_WHO_p1.0
Adcyap1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477011,358,286 - 11,375,813 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462477011,359,606 - 11,375,833 (+)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_021734452   ⟹   XP_021590127
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494464,074,352 - 64,081,544 (+)NCBI
SpeTri2.0NW_0049366723,461,387 - 3,468,053 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_021590127 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3294126 (Get FASTA)   NCBI Sequence Viewer  
  KAG3294127 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_021590127   ⟸   XM_021734452
- Sequence:
Protein Domains
GLUCAGON


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000011453 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000010278 ENTREZGENE
  ENSSTOP00000010278.2 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000011453.3 UniProtKB/TrEMBL
InterPro Glucagon UniProtKB/TrEMBL
  Glucagon_GIP_secretin_VIP UniProtKB/TrEMBL
  PACAP UniProtKB/TrEMBL
NCBI Gene Adcyap1 ENTREZGENE
PANTHER PTHR11213 UniProtKB/TrEMBL
  PTHR11213:SF1 UniProtKB/TrEMBL
Pfam Hormone_2 UniProtKB/TrEMBL
PRINTS GLUCAGON UniProtKB/TrEMBL
PROSITE GLUCAGON UniProtKB/TrEMBL
SMART GLUCA UniProtKB/TrEMBL
UniProt I3MHD0_ICTTR UniProtKB/TrEMBL