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Gene: Ak4 (adenylate kinase 4) Ictidomys tridecemlineatus

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Symbol:

Ak4

Name:

adenylate kinase 4

RGD ID:

12657077

Description:

ENCODES a protein that exhibits adenylate kinase activity (ortholog); nucleoside triphosphate adenylate kinase activity (ortholog); INVOLVED IN cellular response to hypoxia (ortholog); liver development (ortholog); regulation of oxidative phosphorylation (ortholog); PARTICIPATES IN de novo purine biosynthetic pathway; ASSOCIATED WITH acute kidney tubular necrosis (ortholog); Chemical and Drug Induced Liver Injury (ortholog); congenital disorder of glycosylation It (ortholog); FOUND IN mitochondrial matrix (inferred); mitochondrion (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

adenylate kinase 4, mitochondrial; adenylate kinase 4, transcript variant X1; adenylate kinase 4, transcript variant X2; adenylate kinase 4, transcript variant X3; adenylate kinase 4, transcript variant X4; adenylate kinase 4, transcript variant X5

RGD Orthologs

Alliance Orthologs

More Info

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More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	AK4 (adenylate kinase 4)	NCBI	Ortholog
Mus musculus (house mouse):	Ak4 (adenylate kinase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Ak4 (adenylate kinase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ak4 (adenylate kinase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	AK4 (adenylate kinase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	AK4 (adenylate kinase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	AK4 (adenylate kinase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	AK4 (adenylate kinase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ak4 (adenylate kinase 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	78,277,939 - 78,342,917 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936692	2,593,409 - 2,654,583 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute kidney tubular necrosis (ISO)

Chemical and Drug Induced Liver Injury (ISO)

congenital disorder of glycosylation It (ISO)

COVID-19 (ISO)

intellectual disability (ISO)

osteoarthritis (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

ADP biosynthetic process (IEA)

AMP metabolic process (IEA)

ATP metabolic process (IEA)

cellular response to hypoxia (ISO)

GTP metabolic process (IEA)

liver development (ISO)

nucleobase-containing compound metabolic process (IEA)

nucleoside monophosphate phosphorylation (IEA)

regulation of oxidative phosphorylation (ISO)

response to xenobiotic stimulus (ISO)

ribonucleoside diphosphate biosynthetic process (ISO)

Cellular Component

mitochondrial matrix (IEA)

mitochondrion (IEA)

Molecular Function

adenylate kinase activity (IEA,ISO)

ATP binding (IEA)

CMP kinase activity (IEA)

dCMP kinase activity (IEA)

deoxyadenylate kinase activity (IEA)

GTP binding (IEA)

kinase activity (IEA)

nucleobase-containing compound kinase activity (IEA)

nucleoside diphosphate kinase activity (IEA)

nucleoside monophosphate kinase activity (IEA)

nucleoside triphosphate adenylate kinase activity (IEA,ISO)

nucleotide binding (IEA)

phosphotransferase activity, phosphate group as acceptor (IEA)

protein binding (ISO)

transferase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

de novo purine biosynthetic pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Ak4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	78,277,939 - 78,342,917 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936692	2,593,409 - 2,654,583 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

AK4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	65,147,552 - 65,232,145 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	65,147,549 - 65,232,145 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	65,613,235 - 65,697,828 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	65,385,820 - 65,465,765 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	63,903,944 - 63,988,555 (+)	NCBI		Celera
Cytogenetic Map	1	p31.3	NCBI
HuRef	1	63,722,163 - 63,806,551 (+)	NCBI		HuRef
CHM1_1	1	65,729,523 - 65,814,075 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	65,025,531 - 65,110,134 (+)	NCBI		T2T-CHM13v2.0

Ak4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	101,273,675 - 101,324,968 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	101,276,474 - 101,324,192 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	101,416,478 - 101,467,771 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	101,419,277 - 101,466,995 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	101,091,894 - 101,140,376 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	100,917,690 - 100,964,927 (+)	NCBI		MGSCv36	mm8
Celera	4	99,759,270 - 99,808,044 (+)	NCBI		Celera
Cytogenetic Map	4	C6	NCBI
cM Map	4	46.84	NCBI

Ak4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	121,154,565 - 121,214,403 (+)	NCBI		GRCr8
mRatBN7.2	5	116,039,222 - 116,099,064 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	116,039,616 - 116,098,618 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	118,605,105 - 118,655,660 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	120,330,473 - 120,381,010 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	120,381,768 - 120,432,320 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	120,250,318 - 120,309,153 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	120,250,616 - 120,305,897 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	124,129,933 - 124,189,606 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	122,062,872 - 122,119,335 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	122,068,045 - 122,127,564 (+)	NCBI
Celera	5	114,576,993 - 114,626,919 (+)	NCBI		Celera
Cytogenetic Map	5	q33	NCBI

Ak4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955423	25,395,836 - 25,427,474 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955423	25,395,086 - 25,402,324 (-)	NCBI	ChiLan1.0	ChiLan1.0

AK4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	161,630,069 - 161,714,696 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	160,780,900 - 160,865,513 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	64,394,898 - 64,479,536 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	66,283,102 - 66,367,146 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	66,283,102 - 66,361,230 (+)	Ensembl	panpan1.1		panPan2

AK4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	45,055,294 - 45,119,595 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	44,884,283 - 45,120,203 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	45,107,227 - 45,176,810 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	45,230,958 - 45,300,604 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	45,235,891 - 45,300,627 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	45,196,507 - 45,265,914 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	45,140,926 - 45,210,260 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	45,392,014 - 45,461,310 (-)	NCBI		UU_Cfam_GSD_1.0

AK4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	147,177,029 - 147,257,814 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	147,177,029 - 147,257,799 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	135,587,473 - 135,663,801 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

AK4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	67,840,572 - 67,924,691 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666033	49,603,493 - 49,717,228 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ak4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624742	29,547,237 - 29,574,160 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005337722	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021734847	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021734848	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021734849	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021734850	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040288787	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040288788	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000117	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_005337722 ⟹ XP_005337779

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	78,277,947 - 78,342,917 (+)	NCBI
SpeTri2.0	NW_004936692	2,593,409 - 2,654,583 (+)	NCBI

Sequence:

show sequence

GGCGGCCGCCCTGGGCTCGGAGACTGAACAGGCGGAGGCGGCGCCGCCCATTGGGATCCGGGCT
GGGTGTCTCTGGTGGCGCTACTTTCAGCCGAGGGGCGGCAGGAGAGTCCCCGCGTGAGCAGAGG
GTTCCTGAGGCAGGGGCCAAGAAACAAAGTTCGCGGGGCTGCCTCCGGGGCCGCTGTCTGGGCT
GCCTGTTGGGCCGCTCGCCTCCTCGCGAAGGCCATGGCTTCCAAACTCCTGCGCGCGGTCATCC
TAGGGCCGCCTGGCTCGGGCAAGGGCACCGTTTGCCAGAGGATCGCCCAGAACTTTGGCCTCCA
GCATCTCTCCAGTGGCCACTTCTTGCGGGAGAACCTCAAAGCCAACACGGAAGTTGGCGAAATG
GCAAGGCAGTACCTGGAGAAAGGTCTTTTGGTTCCAGATCACGTGATCACACGCCTAATGGTGT
CAGAGCTGGAGCTCAGGAGCGGCCAACACTGGCTACTGGATGGTTTTCCAAGGACAATAGTACA
GGCTGAAGCCCTTGACAAAATCTGTGACCTGGATCTAGTGATCAGTTTGAACATTCCATTTGAA
ACACTTAAAGATCGTCTCAGTCGACGTTGGATTCACCGTCCTAGTGGAAGAGTCTATAATTTGG
ACTTCAACCCACCCCATGTGCATGGAATTGATGACATCACTGGTGAGCCACTCGTCCAGCAGGA
GGATGATAAGCCTGAAGCGGTTGCTGCCAAGCTAAGACGGTATAAAGATGCAGCTAAACCAGTC
ATCGAACTATACAAGAGTCGAGGAGTTCTCCACCAATTTTCTGGGACGGAGACAAACAGAATCT
GGCCTTATGTTTACACACTGTTCTCCAACAAGATCACACCTATTCAGTCCAAAGAAGCCTACTG
AGCCTGTCCCATGGAAGAACCAAGAAGATGTGGTCATTCATTCAATCGTGTGTGTAGCATTGAT
GCCATGTCCAAATTAGAAGTCAGCTGAGATAGCGTACAGCATCTTTTCTGTGTAAATGGTGAAC
TGATAGGAAAACTAGTAAATAGAAAGGGCTCGTGAGGAGGCCCTTCTCTGTCTTTCAAAAGAAG
GCAATTCTGGACCTGTCAAGCCCTTCACAAGCAAGCTCGTGCAGGCTGGATTTCAGGTGTCTAA
CCTACACTCTAGTTGGGTTTGGACAGCCAAGTTGTTGCTTTAATAGCCTCTTTTTGCATGTGAT
GACAGTGGTCTCTGGTTCTCCCCACCCTTCCAAGGCTGTATTGAAACACAGAACCAGTAAACAC
GAGAATGCAGAGGACGCTAGTCTTGGCTTTGCCACAGTTCTCTGCTTTGTGCCCCCTCGTAACA
GTGGAATTGAATCTTATTGCTCTCAGTGGTTGCTTACCTTGAGTGACTGTGTTCACAATTCATT
TTTTTTTTCCTGCTAAGAGTAACACCTTTCATCCATGCTCCACAGTGTCTCTCCTTTGCAGACA
TCCTGGAATGAAAGGATTTGTTTTCTTACATCTGTTTTCTCTCATCTTAGGATATTAAATAGAG
GCTATTAAATAATACAGATAGTTGCTGCATTTATCCCTCTCAGATTTGTTTTTTATGAACTGAG
AGCTAGGGGTTACATTGAATCTCTTCATGCATCATGAACTGAGCCATGCAGAGGGTCTTATTTA
AAGGCTGGTCTGATTCTCATGGGCTTGTTCTGCTCATTTTATTGTGAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_021734850 ⟹ XP_021590525

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	78,277,939 - 78,342,917 (+)	NCBI
SpeTri2.0	NW_004936692	2,593,741 - 2,654,583 (+)	NCBI

Sequence:

show sequence

GGCGGGGCGGCGGGGGCGCGCTTTGAGTCACCCCCTTATCTCGGTTTCCTTAGCTAGTCCGAGA
CTGGTTTGGGGATGCCTGGCCACACGACTCCCTCCTAGGACAAGGCGTGGGAGTGAGACAGCGG
AAGGGATCGAGATTGGAACTGGCGGGCCGACCTCCGCGCCCCCGAGGGCTGACTACGCTGGGCG
GGGGCATTGGAGTTCTCCATAACTGCTGCCTGGGGGCGAGGAGGTGGCGGAGGGCGGGGCTGAG
GGGAGGGGTTGTCTTAAAAGTCTCTCCTTTCCCCAGTAGGGGCGGCAGGAGAGTCCCCGCGTGA
GCAGAGGGTTCCTGAGGCAGGGGCCAAGAAACAAAGTTCGCGGGGCTGCCTCCGGGGCCGCTGT
CTGGGCTGCCTGTTGGGCCGCTCGCCTCCTCGCGAAGGCCATGGCTTCCAAACTCCTGCGCGCG
GTCATCCTAGGGCCGCCTGGCTCGGGCAAGGGCACCGTTTGCCAGAGGATCGCCCAGAACTTTG
GCCTCCAGCATCTCTCCAGTGGCCACTTCTTGCGGGAGAACCTCAAAGCCAACACGGGTTTTCC
AAGGACAATAGTACAGGCTGAAGCCCTTGACAAAATCTGTGACCTGGATCTAGTGATCAGTTTG
AACATTCCATTTGAAACACTTAAAGATCGTCTCAGTCGACGTTGGATTCACCGTCCTAGTGGAA
GAGTCTATAATTTGGACTTCAACCCACCCCATGTGCATGGAATTGATGACATCACTGGTGAGCC
ACTCGTCCAGCAGGAGGATGATAAGCCTGAAGCGGTTGCTGCCAAGCTAAGACGGTATAAAGAT
GCAGCTAAACCAGTCATCGAACTATACAAGAGTCGAGGAGTTCTCCACCAATTTTCTGGGACGG
AGACAAACAGAATCTGGCCTTATGTTTACACACTGTTCTCCAACAAGATCACACCTATTCAGTC
CAAAGAAGCCTACTGAGCCTGTCCCATGGAAGAACCAAGAAGATGTGGTCATTCATTCAATCGT
GTGTGTAGCATTGATGCCATGTCCAAATTAGAAGTCAGCTGAGATAGCGTACAGCATCTTTTCT
GTGTAAATGGTGAACTGATAGGAAAACTAGTAAATAGAAAGGGCTCGTGAGGAGGCCCTTCTCT
GTCTTTCAAAAGAAGGCAATTCTGGACCTGTCAAGCCCTTCACAAGCAAGCTCGTGCAGGCTGG
ATTTCAGGTGTCTAACCTACACTCTAGTTGGGTTTGGACAGCCAAGTTGTTGCTTTAATAGCCT
CTTTTTGCATGTGATGACAGTGGTCTCTGGTTCTCCCCACCCTTCCAAGGCTGTATTGAAACAC
AGAACCAGTAAACACGAGAATGCAGAGGACGCTAGTCTTGGCTTTGCCACAGTTCTCTGCTTTG
TGCCCCCTCGTAACAGTGGAATTGAATCTTATTGCTCTCAGTGGTTGCTTACCTTGAGTGACTG
TGTTCACAATTCATTTTTTTTTTCCTGCTAAGAGTAACACCTTTCATCCATGCTCCACAGTGTC
TCTCCTTTGCAGACATCCTGGAATGAAAGGATTTGTTTTCTTACATCTGTTTTCTCTCATCTTA
GGATATTAAATAGAGGCTATTAAATAATACAGATAGTTGCTGCATTTATCCCTCTCAGATTTGT
TTTTTATGAACTGAGAGCTAGGGGTTACATTGAATCTCTTCATGCATCATGAACTGAGCCATGC
AGAGGGTCTTATTTAAAGGCTGGTCTGATTCTCATGGGCTTGTTCTGCTCATTTTATTGTGAAA
AAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_040288787 ⟹ XP_040144721

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	78,277,942 - 78,342,917 (+)	NCBI

RefSeq Acc Id:

XM_040288788 ⟹ XP_040144722

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	78,277,954 - 78,342,917 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_005337779	(Get FASTA)	NCBI Sequence Viewer
	XP_021590525	(Get FASTA)	NCBI Sequence Viewer
	XP_040144721	(Get FASTA)	NCBI Sequence Viewer
	XP_040144722	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000014875.2
GenBank Protein	KAG3283326	(Get FASTA)	NCBI Sequence Viewer
	KAG3283327	(Get FASTA)	NCBI Sequence Viewer
	KAG3283328	(Get FASTA)	NCBI Sequence Viewer
	KAG3283329	(Get FASTA)	NCBI Sequence Viewer
	KAG3283330	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005337779 ⟸ XM_005337722
- Peptide Label:	isoform X1
- UniProtKB:	I3MRY0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MASKLLRAVILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENLKANTEVGEMARQYLEKGLLV PDHVITRLMVSELELRSGQHWLLDGFPRTIVQAEALDKICDLDLVISLNIPFETLKDRLSRRWI HRPSGRVYNLDFNPPHVHGIDDITGEPLVQQEDDKPEAVAAKLRRYKDAAKPVIELYKSRGVLH QFSGTETNRIWPYVYTLFSNKITPIQSKEAY hide sequence

RefSeq Acc Id:	XP_021590525 ⟸ XM_021734850
- Peptide Label:	isoform X2
- Sequence:	show sequence MASKLLRAVILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENLKANTGFPRTIVQAEALDKIC DLDLVISLNIPFETLKDRLSRRWIHRPSGRVYNLDFNPPHVHGIDDITGEPLVQQEDDKPEAVA AKLRRYKDAAKPVIELYKSRGVLHQFSGTETNRIWPYVYTLFSNKITPIQSKEAY hide sequence

RefSeq Acc Id:	XP_040144721 ⟸ XM_040288787
- Peptide Label:	isoform X1
- UniProtKB:	I3MRY0 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_040144722 ⟸ XM_040288788
- Peptide Label:	isoform X3

Protein Domains

Adenylate kinase active site lid

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000023008	UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000028323.2	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.300	UniProtKB/TrEMBL
InterPro	Adenyl_kin_sub	UniProtKB/TrEMBL
	Adenylat/UMP-CMP_kin	UniProtKB/TrEMBL
	Adenylat_kinase_CS	UniProtKB/TrEMBL
	Adenylate_kinase_lid-dom	UniProtKB/TrEMBL
	ADK_active_lid_dom_sf	UniProtKB/TrEMBL
	AK3/Ak4_mitochondrial	UniProtKB/TrEMBL
	AK4_mitochondrial	UniProtKB/TrEMBL
	P-loop_NTPase	UniProtKB/TrEMBL
NCBI Gene	Ak4	ENTREZGENE
PANTHER	PTHR23359	UniProtKB/TrEMBL
Pfam	ADK	UniProtKB/TrEMBL
	ADK_lid	UniProtKB/TrEMBL
PRINTS	ADENYLTKNASE	UniProtKB/TrEMBL
PROSITE	ADENYLATE_KINASE	UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/TrEMBL
	SSF57774	UniProtKB/TrEMBL
UniProt	I3MRY0	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

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RGD Manual Annotations