Rgl1 (ral guanine nucleotide dissociation stimulator like 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Rgl1 (ral guanine nucleotide dissociation stimulator like 1) Ictidomys tridecemlineatus
Analyze
Symbol: Rgl1
Name: ral guanine nucleotide dissociation stimulator like 1
RGD ID: 12656946
Description: ENCODES a protein that exhibits guanyl-nucleotide exchange factor activity (inferred); INVOLVED IN Ras protein signal transduction (inferred); signal transduction (inferred); small GTPase-mediated signal transduction (inferred); ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); parathyroid carcinoma (ortholog); FOUND IN plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ral guanine nucleotide dissociation stimulator like 1, transcript variant X1; ral guanine nucleotide dissociation stimulator like 1, transcript variant X2; ral guanine nucleotide dissociation stimulator like 1, transcript variant X3; ral guanine nucleotide dissociation stimulator-like 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934488,179,408 - 88,420,192 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364816,025,581 - 6,267,012 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364816,026,157 - 6,175,453 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Rgl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934488,179,408 - 88,420,192 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364816,025,581 - 6,267,012 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364816,026,157 - 6,175,453 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RGL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381183,636,109 - 183,928,532 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1183,636,085 - 183,928,532 (+)EnsemblGRCh38hg38GRCh38
GRCh371183,605,244 - 183,897,666 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361181,871,831 - 182,164,289 (+)NCBINCBI36Build 36hg18NCBI36
Build 341180,336,876 - 180,629,322NCBI
Celera1156,716,240 - 157,008,586 (+)NCBICelera
Cytogenetic Map1q25.3NCBI
HuRef1154,841,067 - 155,133,408 (+)NCBIHuRef
CHM1_11185,027,897 - 185,320,329 (+)NCBICHM1_1
T2T-CHM13v2.01182,995,391 - 183,287,882 (+)NCBIT2T-CHM13v2.0
Rgl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391152,392,513 - 152,642,056 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1152,392,511 - 152,642,102 (-)EnsemblGRCm39 Ensembl
GRCm381152,516,762 - 152,766,308 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1152,516,760 - 152,766,351 (-)EnsemblGRCm38mm10GRCm38
MGSCv371154,364,660 - 154,472,241 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361154,279,748 - 154,387,329 (-)NCBIMGSCv36mm8
Celera1154,937,769 - 155,046,515 (-)NCBICelera
Cytogenetic Map1G2- G3NCBI
cM Map164.85NCBI
Ralgdsl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81367,184,402 - 67,454,019 (-)NCBIGRCr8
mRatBN7.21364,634,489 - 64,904,170 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1364,635,246 - 64,904,191 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1367,243,711 - 67,506,393 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01368,520,706 - 68,799,251 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01365,781,720 - 66,050,138 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01369,909,122 - 70,174,590 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1369,909,096 - 70,174,565 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01374,881,101 - 75,145,659 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41367,468,218 - 67,754,947 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11367,483,775 - 67,596,194 (-)NCBI
Celera1364,547,086 - 64,810,801 (-)NCBICelera
Cytogenetic Map13q21NCBI
Rgl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540622,483,336 - 22,670,537 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540622,419,137 - 22,670,537 (+)NCBIChiLan1.0ChiLan1.0
RGL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2165,790,123 - 66,081,962 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1165,473,320 - 65,765,120 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01159,166,090 - 159,457,883 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11163,323,651 - 163,614,657 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1163,429,258 - 163,614,657 (+)Ensemblpanpan1.1panPan2
RGL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1716,986,304 - 17,236,549 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl717,041,296 - 17,235,193 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha716,571,833 - 16,821,876 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0716,718,212 - 16,968,704 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl716,718,185 - 16,968,890 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1716,626,490 - 16,876,720 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0716,735,857 - 16,985,375 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0716,866,935 - 17,116,349 (+)NCBIUU_Cfam_GSD_1.0
RGL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9124,848,338 - 125,144,253 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19124,848,358 - 125,143,014 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29137,178,640 - 137,472,441 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RGL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12545,444,588 - 45,730,912 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2545,444,468 - 45,568,506 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605546,660,856 - 46,947,508 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rgl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248149,746,210 - 9,950,327 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248149,747,154 - 10,062,828 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000015605   ⟹   ENSSTOP00000013968
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364816,028,380 - 6,137,463 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000030618   ⟹   ENSSTOP00000027437
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364816,025,581 - 6,137,719 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000033638   ⟹   ENSSTOP00000027767
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364816,025,581 - 6,267,012 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000036876   ⟹   ENSSTOP00000025433
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364816,025,581 - 6,267,012 (-)Ensembl
RefSeq Acc Id: XM_005319702   ⟹   XP_005319759
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934488,179,408 - 88,290,911 (-)NCBI
SpeTri2.0NW_0049364816,026,157 - 6,137,660 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013356175   ⟹   XP_013211629
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934488,179,408 - 88,420,192 (-)NCBI
SpeTri2.0NW_0049364816,026,157 - 6,175,451 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021722566   ⟹   XP_021578241
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934488,179,408 - 88,420,168 (-)NCBI
SpeTri2.0NW_0049364816,026,157 - 6,175,453 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040277558   ⟹   XP_040133492
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934488,181,631 - 88,420,192 (-)NCBI
RefSeq Acc Id: XM_040277559   ⟹   XP_040133493
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934488,181,631 - 88,420,192 (-)NCBI
RefSeq Acc Id: XM_040277560   ⟹   XP_040133494
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934488,181,631 - 88,420,191 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_013211629   ⟸   XM_013356175
- Peptide Label: isoform X1
- UniProtKB: A0A287D2L5 (UniProtKB/TrEMBL),   I3MQ12 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005319759   ⟸   XM_005319702
- Peptide Label: isoform X2
- UniProtKB: A0A287D1P1 (UniProtKB/TrEMBL),   I3MQ12 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021578241   ⟸   XM_021722566
- Peptide Label: isoform X3
- UniProtKB: A0A287CVY4 (UniProtKB/TrEMBL),   I3MQ12 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040133493   ⟸   XM_040277559
- Peptide Label: isoform X1
- UniProtKB: A0A287D2L5 (UniProtKB/TrEMBL),   I3MQ12 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040133492   ⟸   XM_040277558
- Peptide Label: isoform X1
- UniProtKB: A0A287D2L5 (UniProtKB/TrEMBL),   I3MQ12 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040133494   ⟸   XM_040277560
- Peptide Label: isoform X3
- UniProtKB: A0A287CVY4 (UniProtKB/TrEMBL),   I3MQ12 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000027767   ⟸   ENSSTOT00000033638
RefSeq Acc Id: ENSSTOP00000027437   ⟸   ENSSTOT00000030618
RefSeq Acc Id: ENSSTOP00000025433   ⟸   ENSSTOT00000036876
RefSeq Acc Id: ENSSTOP00000013968   ⟸   ENSSTOT00000015605
Protein Domains
N-terminal Ras-GEF   Ras-associating   Ras-GEF


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000015596 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000015605.3 UniProtKB/TrEMBL
  ENSSTOT00000030618.1 UniProtKB/TrEMBL
  ENSSTOT00000033638.1 UniProtKB/TrEMBL
  ENSSTOT00000036876.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.840.10 UniProtKB/TrEMBL
  Son of sevenless (SoS) protein Chain: S domain 1 UniProtKB/TrEMBL
InterPro RA_dom UniProtKB/TrEMBL
  Ras-like_GEF UniProtKB/TrEMBL
  Ras-like_Gua-exchang_fac_N UniProtKB/TrEMBL
  Ras_G-nucl-exch_fac_CS UniProtKB/TrEMBL
  Ras_GEF_dom_sf UniProtKB/TrEMBL
  RASGEF_cat_dom UniProtKB/TrEMBL
  RASGEF_cat_dom_sf UniProtKB/TrEMBL
  RGL1 UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
NCBI Gene Rgl1 ENTREZGENE
PANTHER PTHR23113 UniProtKB/TrEMBL
  PTHR23113:SF199 UniProtKB/TrEMBL
Pfam PF00788 UniProtKB/TrEMBL
  RasGEF UniProtKB/TrEMBL
  RasGEF_N UniProtKB/TrEMBL
PROSITE PS50200 UniProtKB/TrEMBL
  RASGEF UniProtKB/TrEMBL
  RASGEF_CAT UniProtKB/TrEMBL
  RASGEF_NTER UniProtKB/TrEMBL
SMART RasGEF UniProtKB/TrEMBL
  RasGEFN UniProtKB/TrEMBL
  SM00314 UniProtKB/TrEMBL
Superfamily-SCOP SSF48366 UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
UniProt A0A287CVY4 ENTREZGENE, UniProtKB/TrEMBL
  A0A287D1P1 ENTREZGENE, UniProtKB/TrEMBL
  A0A287D2L5 ENTREZGENE, UniProtKB/TrEMBL
  I3MQ12 ENTREZGENE, UniProtKB/TrEMBL