Hsp90aa1 (heat shock protein 90 alpha family class A member 1) - Rat Genome Database

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Gene: Hsp90aa1 (heat shock protein 90 alpha family class A member 1) Ictidomys tridecemlineatus
Analyze
Symbol: Hsp90aa1
Name: heat shock protein 90 alpha family class A member 1
RGD ID: 12656329
Description: ENCODES a protein that exhibits ATP binding (ortholog); CTP binding (ortholog); dATP binding (ortholog); INVOLVED IN activation of innate immune response (ortholog); cardiac muscle cell apoptotic process (ortholog); cellular response to virus (ortholog); PARTICIPATES IN aldosterone signaling pathway; androgen signaling pathway; chaperone mediated autophagy pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); anaplastic large cell lymphoma (ortholog); Breast Neoplasms (ortholog); FOUND IN apical plasma membrane (ortholog); axonal growth cone (ortholog); basolateral plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: heat shock protein HSP 90-alpha
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244086403,873,950 - 3,879,144 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936835316,767 - 321,990 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936835316,767 - 321,999 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Hsp90aa1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244086403,873,950 - 3,879,144 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936835316,767 - 321,990 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936835316,767 - 321,999 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HSP90AA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3814102,080,742 - 102,139,749 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl14102,080,742 - 102,139,699 (-)EnsemblGRCh38hg38GRCh38
GRCh3714102,547,079 - 102,606,086 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3614101,616,828 - 101,675,839 (-)NCBINCBI36Build 36hg18NCBI36
Build 3414101,617,144 - 101,623,135NCBI
Celera1482,601,564 - 82,660,582 (-)NCBICelera
Cytogenetic Map14q32.31NCBI
HuRef1482,725,979 - 82,785,051 (-)NCBIHuRef
CHM1_114102,484,935 - 102,543,941 (-)NCBICHM1_1
T2T-CHM13v2.01496,316,329 - 96,375,332 (-)NCBIT2T-CHM13v2.0
Hsp90aa1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912110,657,470 - 110,662,829 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12110,657,039 - 110,669,162 (-)EnsemblGRCm39 Ensembl
GRCm3812110,691,036 - 110,696,395 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12110,690,605 - 110,702,728 (-)EnsemblGRCm38mm10GRCm38
MGSCv3712111,929,246 - 111,934,605 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612111,138,843 - 111,144,202 (-)NCBIMGSCv36mm8
Celera12111,881,002 - 111,886,365 (-)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1260.75NCBI
Hsp90aa1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86135,523,604 - 135,529,687 (-)NCBIGRCr8
mRatBN7.26129,702,376 - 129,707,907 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6129,702,383 - 129,707,268 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6129,879,675 - 129,884,976 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06130,175,668 - 130,180,969 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06129,539,256 - 129,544,788 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06135,107,262 - 135,112,793 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6135,107,271 - 135,112,775 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl6135,045,363 - 135,049,728 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06144,182,009 - 144,187,540 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46135,413,616 - 135,419,147 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16135,419,806 - 135,425,334 (-)NCBI
Celera6127,272,361 - 127,277,892 (-)NCBICelera
Cytogenetic Map6q32NCBI
Hsp90aa1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555381,469,544 - 1,475,019 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555381,469,544 - 1,475,010 (-)NCBIChiLan1.0ChiLan1.0
HSP90AA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v215103,233,362 - 103,292,106 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan114102,449,856 - 102,456,012 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01482,700,881 - 82,707,020 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.114102,519,033 - 102,524,639 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl14102,519,699 - 102,576,723 (-)Ensemblpanpan1.1panPan2
HSP90AA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1870,091,203 - 70,096,107 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl870,092,217 - 70,095,243 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha869,605,578 - 69,611,507 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0870,369,324 - 70,375,263 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl870,369,667 - 70,374,704 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1870,033,441 - 70,039,369 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0870,098,797 - 70,104,717 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0870,498,429 - 70,504,357 (-)NCBIUU_Cfam_GSD_1.0
HSP90AA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.27129,758,754 - 129,760,542 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HSP90AA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12480,016,352 - 80,019,130 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2480,016,232 - 80,019,120 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605367,207,536 - 67,213,629 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hsp90aa1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247342,233,547 - 2,241,436 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247342,233,932 - 2,239,687 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005340994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010003700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000009650   ⟹   ENSSTOP00000008658
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936835316,767 - 321,990 (-)Ensembl
RefSeq Acc Id: XM_005340994   ⟹   XP_005341051
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244086403,873,950 - 3,879,144 (+)NCBI
SpeTri2.0NW_004936835316,767 - 321,999 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005341051 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000003001.3
  ENSSTOP00000008658.2
GenBank Protein KAG3260328 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005341051   ⟸   XM_005340994
- UniProtKB: I3MDY9 (UniProtKB/TrEMBL),   I3M249 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000008658   ⟸   ENSSTOT00000009650
Protein Domains
Histidine kinase/HSP90-like ATPase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000003354 UniProtKB/TrEMBL
  ENSSTOG00000009643 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000003353.3 UniProtKB/TrEMBL
  ENSSTOT00000009650.3 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.790 UniProtKB/TrEMBL
  3.30.230.80 UniProtKB/TrEMBL
  3.30.565.10 UniProtKB/TrEMBL
  3.40.50.11260 UniProtKB/TrEMBL
InterPro HATPase_C UniProtKB/TrEMBL
  HATPase_C_sf UniProtKB/TrEMBL
  Heat_shock_protein_90_CS UniProtKB/TrEMBL
  HSP90_C UniProtKB/TrEMBL
  Hsp90_fam UniProtKB/TrEMBL
  Hsp90_N UniProtKB/TrEMBL
  Ribosomal_S5_D2-typ_fold UniProtKB/TrEMBL
NCBI Gene Hsp90aa1 ENTREZGENE
PANTHER HEAT SHOCK PROTEIN HSP 90-ALPHA UniProtKB/TrEMBL
  PTHR11528 UniProtKB/TrEMBL
Pfam HATPase_c_3 UniProtKB/TrEMBL
  HSP90 UniProtKB/TrEMBL
PIRSF Hsp90 UniProtKB/TrEMBL
PRINTS HEATSHOCK90 UniProtKB/TrEMBL
PROSITE HSP90 UniProtKB/TrEMBL
SMART HATPase_c UniProtKB/TrEMBL
Superfamily-SCOP SSF110942 UniProtKB/TrEMBL
  SSF54211 UniProtKB/TrEMBL
  SSF55874 UniProtKB/TrEMBL
UniProt I3M249 ENTREZGENE, UniProtKB/TrEMBL
  I3MDY9 ENTREZGENE, UniProtKB/TrEMBL