Spry1 (sprouty RTK signaling antagonist 1) - Rat Genome Database

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Gene: Spry1 (sprouty RTK signaling antagonist 1) Ictidomys tridecemlineatus
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Symbol: Spry1
Name: sprouty RTK signaling antagonist 1
RGD ID: 12655721
Description: INVOLVED IN bud elongation involved in lung branching (ortholog); epithelial to mesenchymal transition involved in cardiac fibroblast development (ortholog); ERK1 and ERK2 cascade (ortholog); ASSOCIATED WITH genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); Peritoneal Fibrosis (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); Golgi apparatus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sprouty homolog 1, antagonist of FGF signaling
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530164,874,359 - 64,879,870 (-)NCBI
SpeTri2.0NW_0049366622,241,928 - 2,245,616 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA)
Golgi apparatus  (IEA)
membrane  (IEA)
nucleoplasm  (IEA)

Molecular Function

References

Genomics

Comparative Map Data
Spry1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530164,874,359 - 64,879,870 (-)NCBI
SpeTri2.0NW_0049366622,241,928 - 2,245,616 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPRY1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384123,396,795 - 123,403,760 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl4123,396,795 - 123,403,760 (+)EnsemblGRCh38hg38GRCh38
GRCh374124,317,950 - 124,324,915 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364124,537,406 - 124,544,360 (+)NCBINCBI36hg18NCBI36
Build 344124,675,560 - 124,682,512NCBI
Celera4121,700,490 - 121,707,443 (+)NCBI
Cytogenetic Map4q28.1NCBI
HuRef4120,044,807 - 120,051,767 (+)NCBIHuRef
CHM1_14124,294,629 - 124,301,588 (+)NCBICHM1_1
T2T-CHM13v2.04126,700,894 - 126,707,854 (+)NCBI
Spry1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39337,694,096 - 37,698,748 (+)NCBIGRCm39mm39
GRCm39 Ensembl337,694,096 - 37,698,747 (+)Ensembl
GRCm38337,639,947 - 37,644,599 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl337,639,947 - 37,644,598 (+)EnsemblGRCm38mm10GRCm38
MGSCv37337,538,872 - 37,543,521 (+)NCBIGRCm37mm9NCBIm37
MGSCv36337,831,525 - 37,836,146 (+)NCBImm8
Celera337,514,171 - 37,518,800 (+)NCBICelera
Cytogenetic Map3BNCBI
Spry1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22120,557,276 - 120,561,918 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl2120,556,706 - 120,566,189 (+)Ensembl
Rnor_6.02124,400,689 - 124,405,331 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2124,400,679 - 124,405,331 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02144,010,441 - 144,015,083 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42124,213,692 - 124,218,334 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12124,164,062 - 124,168,594 (+)NCBI
Celera2115,501,106 - 115,505,962 (+)NCBICelera
Cytogenetic Map2q25NCBI
Spry1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542817,451,703 - 17,455,695 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542817,451,703 - 17,455,695 (-)NCBIChiLan1.0ChiLan1.0
SPRY1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.14126,715,650 - 126,720,973 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4126,718,811 - 126,719,770 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v04115,570,788 - 115,578,824 (+)NCBIMhudiblu_PPA_v0panPan3
SPRY1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11916,969,869 - 16,976,573 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1916,970,904 - 16,972,089 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1917,183,429 - 17,189,923 (-)NCBI
ROS_Cfam_1.01917,082,115 - 17,088,610 (-)NCBI
ROS_Cfam_1.0 Ensembl1917,079,998 - 17,088,580 (-)Ensembl
UMICH_Zoey_3.11917,039,814 - 17,046,311 (-)NCBI
UNSW_CanFamBas_1.01917,317,762 - 17,324,256 (-)NCBI
UU_Cfam_GSD_1.01917,789,162 - 17,795,661 (-)NCBI
SPRY1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8100,450,266 - 100,863,446 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18100,449,476 - 100,863,780 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28108,191,807 - 108,199,235 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SPRY1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1770,626,524 - 70,634,084 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl770,631,925 - 70,632,884 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603749,599,467 - 49,606,489 (+)NCBIVero_WHO_p1.0
Spry1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247773,731,299 - 3,735,373 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046247773,728,984 - 3,735,373 (+)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005336519   ⟹   XP_005336576
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530164,874,359 - 64,877,854 (-)NCBI
SpeTri2.0NW_0049366622,241,928 - 2,245,616 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040293322   ⟹   XP_040149256
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530164,874,359 - 64,879,827 (-)NCBI
RefSeq Acc Id: XR_005737394
RefSeq Status:
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440530164,878,884 - 64,879,870 (-)NCBI
Protein Sequences
Protein RefSeqs XP_005336576 (Get FASTA)   NCBI Sequence Viewer  
  XP_040149256 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3276217 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005336576   ⟸   XM_005336519
- Sequence:
RefSeq Acc Id: XP_040149256   ⟸   XM_040293322


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000019856 UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000020608.2 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000028806.2 UniProtKB/TrEMBL
InterPro Sprouty UniProtKB/TrEMBL
  SPRY1 UniProtKB/TrEMBL
NCBI Gene Spry1 ENTREZGENE
PANTHER PTHR12365:SF10 UniProtKB/TrEMBL
Pfam Sprouty UniProtKB/TrEMBL
PROSITE SPR UniProtKB/TrEMBL
UniProt I3N8B2_ICTTR UniProtKB/TrEMBL