Lhcgr (luteinizing hormone/choriogonadotropin receptor) - Rat Genome Database

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Gene: Lhcgr (luteinizing hormone/choriogonadotropin receptor) Ictidomys tridecemlineatus
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Symbol: Lhcgr
Name: luteinizing hormone/choriogonadotropin receptor
RGD ID: 12655312
Description: ENCODES a protein that exhibits ATPase binding (ortholog); G protein-coupled peptide receptor activity (ortholog); identical protein binding (ortholog); INVOLVED IN activation of adenylate cyclase activity (ortholog); adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ortholog); arachidonic acid secretion (ortholog); PARTICIPATES IN G protein mediated signaling pathway via Galphas family; luteinizing hormone signaling pathway; peptide and protein hormone signaling pathway; ASSOCIATED WITH 46, XY Disorders of Sex Development (ortholog); Anorchia (ortholog); breast cancer (ortholog); FOUND IN cytoplasm (ortholog); endoplasmic reticulum (ortholog); endosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: lutropin-choriogonadotropic hormone receptor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629232,499,857 - 32,557,352 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365083,928,466 - 3,983,890 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049365083,928,467 - 3,983,481 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of adenylate cyclase activity  (IEA,ISO)
adenylate cyclase-activating G protein-coupled receptor signaling pathway  (IEA)
adenylate cyclase-modulating G protein-coupled receptor signaling pathway  (ISO)
arachidonic acid secretion  (ISO)
cellular response to gonadotropin stimulus  (IEA)
cellular response to luteinizing hormone stimulus  (IEA)
central nervous system development  (ISO)
cognition  (IEA)
development of secondary male sexual characteristics  (IEA,ISO)
female gonad development  (IEA,ISO)
G protein-coupled receptor signaling pathway  (IEA)
hormone-mediated signaling pathway  (ISO)
luteinizing hormone signaling pathway  (IEA,ISO)
male gonad development  (IEA,ISO)
ovarian follicle development  (IEA,ISO)
ovulation cycle process  (IEA,ISO)
phospholipase C-activating G protein-coupled receptor signaling pathway  (IEA,ISO)
positive regulation of calcium ion transport into cytosol  (ISO)
positive regulation of calcium-mediated signaling  (ISO)
positive regulation of hormone biosynthetic process  (ISO)
positive regulation of inositol trisphosphate biosynthetic process  (IEA)
positive regulation of release of sequestered calcium ion into cytosol  (ISO)
protein targeting to lysosome  (ISO)
regulation of steroid biosynthetic process  (ISO)
regulation of steroid hormone biosynthetic process  (IEA,ISO)
response to luteinizing hormone  (ISO)
response to xenobiotic stimulus  (ISO)
seminiferous tubule development  (IEA,ISO)
signal transduction  (IEA)
spermatogenesis  (IEA,ISO)
uterus development  (IEA,ISO)

Cellular Component

References

Genomics

Comparative Map Data
Lhcgr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629232,499,857 - 32,557,352 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365083,928,466 - 3,983,890 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049365083,928,467 - 3,983,481 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LHCGR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38248,686,774 - 48,755,724 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl248,686,774 - 48,755,730 (-)EnsemblGRCh38hg38GRCh38
GRCh37248,913,913 - 48,982,863 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36248,767,417 - 48,836,367 (-)NCBINCBI36Build 36hg18NCBI36
Build 34248,825,619 - 48,894,468NCBI
Celera248,754,221 - 48,823,183 (-)NCBICelera
Cytogenetic Map2p16.3NCBI
HuRef248,647,284 - 48,716,442 (-)NCBIHuRef
CHM1_1248,844,653 - 48,913,614 (-)NCBICHM1_1
T2T-CHM13v2.0248,682,806 - 48,751,772 (-)NCBIT2T-CHM13v2.0
Lhcgr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391789,023,812 - 89,099,487 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1789,023,909 - 89,099,418 (-)EnsemblGRCm39 Ensembl
GRCm381788,716,384 - 88,792,059 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1788,716,481 - 88,791,990 (-)EnsemblGRCm38mm10GRCm38
MGSCv371789,140,889 - 89,191,316 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361788,649,875 - 88,700,302 (-)NCBIMGSCv36mm8
Celera1793,149,952 - 93,199,996 (-)NCBICelera
Cytogenetic Map17E4NCBI
cM Map1758.35NCBI
Lhcgr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.265,661,871 - 5,728,109 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl65,661,871 - 5,724,521 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx65,950,334 - 6,013,310 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.066,259,709 - 6,322,689 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.065,786,872 - 5,849,858 (+)NCBIRnor_WKY
Rnor_6.0612,493,182 - 12,554,482 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl612,493,943 - 12,554,439 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0622,455,216 - 22,516,430 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4612,613,622 - 12,651,587 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1612,613,621 - 12,651,587 (-)NCBI
Celera65,442,191 - 5,504,330 (+)NCBICelera
Cytogenetic Map6q12NCBI
Lhcgr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544115,207,252 - 15,242,914 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544115,205,883 - 15,263,617 (-)NCBIChiLan1.0ChiLan1.0
LHCGR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A49,728,994 - 49,798,780 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A49,729,002 - 49,798,780 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A48,808,822 - 48,879,021 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
LHCGR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11050,540,706 - 50,594,336 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1050,541,960 - 50,598,036 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1050,394,259 - 50,456,607 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01051,416,899 - 51,479,209 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1051,417,733 - 51,474,628 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11051,119,798 - 51,182,164 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01051,404,008 - 51,466,313 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01051,595,139 - 51,657,483 (-)NCBIUU_Cfam_GSD_1.0
LHCGR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl391,964,415 - 92,021,398 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1391,964,415 - 92,023,821 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2397,929,099 - 97,949,675 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap3q22-q23NCBI
LHCGR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11458,413,334 - 58,479,124 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1458,413,993 - 58,477,987 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604553,365,608 - 53,428,814 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lhcgr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473829,903,571 - 29,966,915 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473829,902,364 - 29,967,384 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000024208   ⟹   ENSSTOP00000022756
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365083,928,466 - 3,983,890 (+)Ensembl
RefSeq Acc Id: XM_040271114   ⟹   XP_040127048
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440629232,499,857 - 32,557,352 (+)NCBI
RefSeq Acc Id: XM_040271115   ⟹   XP_040127049
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440629232,499,858 - 32,553,555 (+)NCBI
Protein Sequences
Protein RefSeqs XP_040127048 (Get FASTA)   NCBI Sequence Viewer  
  XP_040127049 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3267334 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_040127048   ⟸   XM_040271114
- Peptide Label: isoform X1
- UniProtKB: I3NEF9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040127049   ⟸   XM_040271115
- Peptide Label: isoform X2
RefSeq Acc Id: ENSSTOP00000022756   ⟸   ENSSTOT00000024208
Protein Domains
G_PROTEIN_RECEP_F1_2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000023268 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000022756.1 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000024208.2 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Gphrmn_rcpt_fam UniProtKB/TrEMBL
  LRR_5 UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  LSH_rcpt UniProtKB/TrEMBL
NCBI Gene Lhcgr ENTREZGENE
Pfam 7tm_1 UniProtKB/TrEMBL
  LRR_5 UniProtKB/TrEMBL
PRINTS GLYCHORMONER UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/TrEMBL
  LSHRECEPTOR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
UniProt I3NEF9 ENTREZGENE, UniProtKB/TrEMBL