Rab21 (RAB21, member RAS oncogene family) - Rat Genome Database

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Gene: Rab21 (RAB21, member RAS oncogene family) Ictidomys tridecemlineatus
Analyze
Symbol: Rab21
Name: RAB21, member RAS oncogene family
RGD ID: 12652839
Description: ENCODES a protein that exhibits GDP binding (inferred); GTP binding (inferred); GTPase activity (inferred); INVOLVED IN regulation of axon extension (ortholog); ASSOCIATED WITH genetic disease (ortholog); obesity (ortholog); FOUND IN synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ras-related protein Rab-21
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494544,881,896 - 44,913,662 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936568814,656 - 846,206 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936568814,647 - 846,426 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
genetic disease  (ISO)
obesity  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Rab21
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494544,881,896 - 44,913,662 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936568814,656 - 846,206 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936568814,647 - 846,426 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RAB21
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381271,754,863 - 71,800,286 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1271,754,863 - 71,800,286 (+)EnsemblGRCh38hg38GRCh38
GRCh371272,148,643 - 72,194,066 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361270,434,925 - 70,467,417 (+)NCBINCBI36Build 36hg18NCBI36
Build 341270,434,924 - 70,467,417NCBI
Celera1271,810,833 - 71,843,321 (+)NCBICelera
Cytogenetic Map12q21.1NCBI
HuRef1269,197,233 - 69,230,012 (+)NCBIHuRef
CHM1_11272,115,800 - 72,148,290 (+)NCBICHM1_1
T2T-CHM13v2.01271,732,345 - 71,777,766 (+)NCBIT2T-CHM13v2.0
Rab21
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910115,125,767 - 115,151,540 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10115,122,989 - 115,151,499 (-)EnsemblGRCm39 Ensembl
GRCm3810115,289,862 - 115,317,419 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10115,287,084 - 115,315,594 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710114,726,918 - 114,752,647 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610114,693,972 - 114,719,701 (-)NCBIMGSCv36mm8
Celera10117,219,099 - 117,244,914 (-)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1063.51NCBI
Rab21
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8752,790,158 - 52,814,943 (-)NCBIGRCr8
mRatBN7.2750,904,050 - 50,928,890 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl750,904,057 - 50,928,839 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx752,810,830 - 52,835,615 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0755,013,914 - 55,038,699 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0754,791,894 - 54,816,679 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0758,261,985 - 58,286,770 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl758,261,992 - 58,286,770 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0758,270,887 - 58,295,672 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4754,550,247 - 54,575,032 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1754,570,880 - 54,595,665 (-)NCBI
Celera747,696,205 - 47,720,990 (-)NCBICelera
Cytogenetic Map7q22NCBI
Rab21
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540511,765,857 - 11,777,192 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540511,766,674 - 11,778,637 (+)NCBIChiLan1.0ChiLan1.0
RAB21
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21079,783,659 - 79,818,267 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11279,780,063 - 79,814,666 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01269,278,191 - 69,309,143 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11272,137,432 - 72,171,844 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1272,137,432 - 72,171,844 (+)Ensemblpanpan1.1panPan2
RAB21
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11013,288,103 - 13,328,246 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1013,216,567 - 13,326,492 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1013,227,000 - 13,267,061 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01013,423,972 - 13,464,145 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1013,368,028 - 13,462,394 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11013,286,016 - 13,326,100 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01013,533,922 - 13,574,199 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01013,657,529 - 13,697,849 (+)NCBIUU_Cfam_GSD_1.0
TMEM19
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl535,757,494 - 35,787,654 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1535,757,273 - 35,788,754 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2538,458,562 - 38,490,039 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RAB21
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11167,379,415 - 67,411,424 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1167,379,397 - 67,411,368 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037178,237,720 - 178,271,773 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rab21
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475025,934,555 - 25,958,129 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475025,934,351 - 25,958,376 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005330419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000011609   ⟹   ENSSTOP00000010418
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936568814,656 - 846,206 (+)Ensembl
RefSeq Acc Id: XM_005330419   ⟹   XP_005330476
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494544,881,896 - 44,913,662 (-)NCBI
SpeTri2.0NW_004936568814,647 - 846,426 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005330476 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000010418.2
GenBank Protein KAG3291365 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005330476   ⟸   XM_005330419
- UniProtKB: I3MHN5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000010418   ⟸   ENSSTOT00000011609


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000011609 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000011609.3 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Rab21 UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
  Small_GTPase UniProtKB/TrEMBL
NCBI Gene Rab21 ENTREZGENE
PANTHER PTHR47978 UniProtKB/TrEMBL
  RAS-RELATED PROTEIN RAB-21 UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
SMART RAB UniProtKB/TrEMBL
  RAN UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt I3MHN5 ENTREZGENE, UniProtKB/TrEMBL