Irf2bp1 (interferon regulatory factor 2 binding protein 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Irf2bp1 (interferon regulatory factor 2 binding protein 1) Ictidomys tridecemlineatus
Analyze
Symbol: Irf2bp1
Name: interferon regulatory factor 2 binding protein 1
RGD ID: 12652194
Description: ENCODES a protein that exhibits transcription corepressor activity (inferred); ubiquitin protein ligase activity (inferred); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: interferon regulatory factor 2-binding protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934917,863,540 - 17,866,588 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367062,211,280 - 2,213,034 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367062,210,882 - 2,213,432 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleoplasm  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Irf2bp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934917,863,540 - 17,866,588 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367062,211,280 - 2,213,034 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367062,210,882 - 2,213,432 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IRF2BP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381945,883,608 - 45,886,141 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1945,883,608 - 45,886,141 (-)EnsemblGRCh38hg38GRCh38
GRCh371946,386,866 - 46,389,399 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361951,078,706 - 51,081,216 (-)NCBINCBI36Build 36hg18NCBI36
Build 341951,078,705 - 51,081,216NCBI
Celera1943,191,891 - 43,194,401 (-)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1942,815,299 - 42,817,809 (-)NCBIHuRef
CHM1_11946,389,361 - 46,391,871 (-)NCBICHM1_1
T2T-CHM13v2.01948,711,051 - 48,713,583 (-)NCBIT2T-CHM13v2.0
Irf2bp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39718,737,983 - 18,740,688 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl718,737,969 - 18,740,702 (+)EnsemblGRCm39 Ensembl
GRCm38719,004,058 - 19,006,763 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl719,004,044 - 19,006,777 (+)EnsemblGRCm38mm10GRCm38
MGSCv37719,589,414 - 19,592,112 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36718,162,587 - 18,165,285 (+)NCBIMGSCv36mm8
Celera716,415,744 - 16,418,444 (+)NCBICelera
Cytogenetic Map7A3NCBI
cM Map79.46NCBI
Irf2bp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8187,780,782 - 87,783,483 (+)NCBIGRCr8
mRatBN7.2178,652,736 - 78,655,437 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl178,652,412 - 78,655,530 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx184,041,771 - 84,044,472 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0192,599,367 - 92,602,068 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0185,796,871 - 85,799,572 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0179,911,516 - 79,914,217 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl179,911,516 - 79,914,217 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0181,171,966 - 81,174,667 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4178,358,171 - 78,360,872 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1178,436,269 - 78,438,994 (+)NCBI
Celera173,118,814 - 73,121,515 (+)NCBICelera
Cytogenetic Map1q21NCBI
Irf2bp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955574308,947 - 312,853 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955574309,506 - 311,759 (-)NCBIChiLan1.0ChiLan1.0
IRF2BP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22052,049,602 - 52,052,159 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11953,921,001 - 53,923,804 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01942,893,381 - 42,896,189 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11951,428,693 - 51,432,920 (-)NCBIpanpan1.1PanPan1.1panPan2
IRF2BP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11109,737,988 - 109,740,915 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1109,738,756 - 109,740,510 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1109,223,423 - 109,226,278 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01110,270,851 - 110,273,707 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1110,271,404 - 110,273,703 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11109,946,860 - 109,949,713 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01109,581,568 - 109,584,421 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01110,450,331 - 110,453,187 (+)NCBIUU_Cfam_GSD_1.0
IRF2BP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl652,196,711 - 52,200,215 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1652,196,709 - 52,200,210 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2647,460,340 - 47,462,867 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IRF2BP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1639,329,839 - 39,332,670 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl639,330,249 - 39,332,003 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607318,972,022 - 18,974,912 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Irf2bp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248327,329,881 - 7,331,635 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248327,329,499 - 7,332,045 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005338242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010004409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000025429   ⟹   ENSSTOP00000015757
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049367062,211,280 - 2,213,034 (-)Ensembl
RefSeq Acc Id: XM_005338242   ⟹   XP_005338299
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934917,863,540 - 17,866,588 (-)NCBI
SpeTri2.0NW_0049367062,210,882 - 2,213,432 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005338299 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000015757.1
GenBank Protein KAG3256283 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005338299   ⟸   XM_005338242
- UniProtKB: I3MUG2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000015757   ⟸   ENSSTOT00000025429
Protein Domains
Interferon regulatory factor 2-binding protein 1 &


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000028673 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000025429.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.1580 UniProtKB/TrEMBL
InterPro I2BP1/2_C3HC4-RING_sf UniProtKB/TrEMBL
  Interferon_reg_fac2-bd1_2_Znf UniProtKB/TrEMBL
NCBI Gene Irf2bp1 ENTREZGENE
PANTHER INTERFERON REGULATORY FACTOR 2-BINDING PROTEIN 1 UniProtKB/TrEMBL
  MYELIN TRANSCRIPTION FACTOR 1-RELATED UniProtKB/TrEMBL
Pfam IRF-2BP1_2 UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
UniProt I3MUG2 ENTREZGENE, UniProtKB/TrEMBL