Tbpl1 (TATA-box binding protein like 1)

Gene: Tbpl1 (TATA-box binding protein like 1) Ictidomys tridecemlineatus

Analyze

Symbol:

Tbpl1

Name:

TATA-box binding protein like 1

RGD ID:

12650988

Description:

ENCODES a protein that exhibits DNA binding (inferred); general transcription initiation factor activity (inferred); RNA polymerase II core promoter sequence-specific DNA binding (inferred); INVOLVED IN acrosome assembly (ortholog); dTTP biosynthetic process (ortholog); spermatid nucleus differentiation (ortholog); ASSOCIATED WITH genetic disease (ortholog); FOUND IN cytoplasm (inferred); male germ cell nucleus (inferred); nucleus (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

TATA box-binding protein-like 1; TATA box-binding protein-like protein 1

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	122,018,007 - 122,050,977 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936560	1,797,333 - 1,830,188 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936560	1,797,791 - 1,830,199 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

acrosome assembly (IEA,ISO)

DNA-templated transcription initiation (IEA)

dTTP biosynthetic process (IEA,ISO)

spermatid nucleus differentiation (IEA,ISO)

spermatogenesis (IEA,ISO)

transcription by RNA polymerase II (IEA)

Cellular Component

cytoplasm (IEA)

male germ cell nucleus (IEA)

nucleus (IEA)

transcription factor TFIIA complex (IEA)

Molecular Function

DNA binding (IEA)

general transcription initiation factor activity (IEA)

protein binding (ISO)

RNA polymerase II core promoter sequence-specific DNA binding (IEA)

RNA polymerase II general transcription initiation factor activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Tbpl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	122,018,007 - 122,050,977 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936560	1,797,333 - 1,830,188 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936560	1,797,791 - 1,830,199 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TBPL1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	133,952,174 - 133,990,432 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	133,952,170 - 133,990,432 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	6	134,273,312 - 134,311,570 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	134,315,994 - 134,350,322 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	6	134,315,993 - 134,350,322	NCBI
Celera	6	135,015,381 - 135,049,709 (+)	NCBI		Celera
Cytogenetic Map	6	q23.2	NCBI
HuRef	6	131,841,901 - 131,877,571 (+)	NCBI		HuRef
CHM1_1	6	134,535,432 - 134,570,879 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	135,140,198 - 135,178,439 (+)	NCBI		T2T-CHM13v2.0

Tbpl1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	22,579,776 - 22,607,882 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	22,579,778 - 22,607,837 (-)	Ensembl		GRCm39 Ensembl
GRCm38	10	22,703,877 - 22,732,666 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	22,703,879 - 22,731,938 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	22,423,683 - 22,451,253 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	22,393,295 - 22,420,794 (-)	NCBI		MGSCv36	mm8
Celera	10	23,650,605 - 23,678,195 (-)	NCBI		Celera
Cytogenetic Map	10	A3	NCBI
cM Map	10	10.25	NCBI

Tbpl1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	24,597,028 - 24,622,445 (+)	NCBI		GRCr8
mRatBN7.2	1	22,777,892 - 22,803,305 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	22,778,459 - 22,803,122 (+)	Ensembl		mRatBN7.2 Ensembl
mRatBN7.2 Ensembl	1	22,778,492 - 22,803,302 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	22,557,426 - 22,582,254 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	28,557,211 - 28,582,034 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	22,754,476 - 22,779,301 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	23,977,154 - 24,002,512 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	23,977,688 - 24,002,506 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	25,441,466 - 25,466,751 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	23,295,515 - 23,320,298 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	23,298,484 - 23,322,895 (+)	NCBI
Celera	1	21,506,025 - 21,530,791 (+)	NCBI		Celera
Cytogenetic Map	1	p12	NCBI

Tbpl1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955439	2,539,486 - 2,563,720 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955439	2,539,465 - 2,548,351 (-)	NCBI	ChiLan1.0	ChiLan1.0

TBPL1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	153,924,706 - 153,961,201 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	151,832,288 - 151,867,648 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	131,719,606 - 131,754,960 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	135,817,603 - 135,852,876 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	135,817,613 - 135,852,876 (+)	Ensembl	panpan1.1		panPan2

TBPL1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	26,898,344 - 26,938,452 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	26,899,859 - 26,936,995 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	27,781,262 - 27,818,400 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	27,056,795 - 27,097,278 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	27,058,291 - 27,096,959 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	26,942,064 - 26,979,193 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	26,822,118 - 26,859,272 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	27,131,596 - 27,168,730 (+)	NCBI		UU_Cfam_GSD_1.0

TBPL1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	29,899,850 - 29,936,680 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	29,899,956 - 29,936,773 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	33,403,547 - 33,440,366 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TBPL1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	13	39,487,007 - 39,523,752 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	13	39,483,880 - 39,522,115 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	11,670,816 - 11,708,059 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tbpl1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624942	819,106 - 847,929 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624942	819,099 - 848,240 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005329776	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040283356	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000006778 ⟹ ENSSTOP00000006061

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936560	1,797,333 - 1,830,188 (+)	Ensembl

RefSeq Acc Id:

XM_005329776 ⟹ XP_005329833

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404946	122,018,625 - 122,050,977 (+)	NCBI
SpeTri2.0	NW_004936560	1,797,791 - 1,830,199 (+)	NCBI

Sequence:

show sequence

CTCTAGCCCCTGCGCGCCGTCTCTATGCTCCTCCGCGTCTGGTCTATTTATTGTCGCGGGGAAG
CAGGGGCCGCCCTGTACCCGGAACAACAAAGCACGAAAGACGGAGCCCGAGCCTCGGGGGCTCC
TAGCAACGGGCCGGGGCGGGAGTTCCATGGAGACTGGGGAGCGCGCCCGCCTCATCTTCATTCT
TGTGCTCCAGCTTCTCCTTCGCATCCGACGCAACCGGCAGCAGCGCTGCCGCCGCGTCCTCTGC
GGCCGCCCCGTCTTCCCACGGATGTGATCTTCGTGGCCAGAAGCTAAGTTTTAAACTACCCCAA
TGGATGCAGACAGTGATGTTGCATTGGACATTCTAATTACAAATGTAGTCTGTGTTTTTAGAAC
AAGATGCCATTTGAACTTAAGAAAGATTGCTTTGGAGGGAGCAAATGTAATTTATAAGCGTGAT
GTTGGGAAAGTATTAATGAAGCTTAGGAAACCTAGAATTACAGCTACAATTTGGTCCTCAGGAA
AAATTATTTGCACTGGAGCAACAAGTGAAGAAGAAGCTAAATTTGGTGCCAGACGTTTAGCCCG
CAGTCTGCAGAAATTAGGTTTTCAGGTAATATTTACAGATTTTAAGGTTGTTAATGTTTTGGCA
GTTTGTAACATGCCCTTTGAAATCCGTTTGCCAGAATTCACAAAGAACAATAGACCTCATGCCA
GTTATGAACCTGAACTTCATCCTGCTGTGTGCTATCGGATAAAGTCTCTAAGAGCTACATTACA
GATTTTTTCAACAGGAAGTATCACAGTAACAGGGCCCAATGTAAAGGCTGTGGCTACTGCTGTG
GAACAAATATACCCATTTGTGTTTGAAAGCAGGAAAGAAATTTTATAACTCATCACTTAATTGG
TTAGAATCTCTAACTGAGCACCTTTTAAAACCTGCTGCACATTGGACTCAAAGCAAAAGGAAAA
CTGGACCAACAGTAATTGAGGAAATAGACTCTTTTATTCACTCACGGCTACAGTGTAAGCTCCA
GTCCCTTTGGATTTTATTTCAAACTTTGCTGTAATATAAAAAGGAAGTTTACAAGACATGACAT
TGCTGCTTTTACAAAAGGACATTCTATTTATTTTCGCAGTAATTCTCATGTCCCCATAAGCAGA
GCTGTCACAATGTGCACTACCTTAAATTGTTTTATTGTTGTCATTGTAATTTTTTTCCAGTTTG
AGCTAATGTGTTTTATTTGTGAATAGTCTTTTACATTTTTGTATGCTGAATATGGGCACCAAAG
AACCTGTAAAAGTTATCTTTTTCAATTGAATGTGCACAAATAAAAGTTTGGAAAAGATCTTTAT
TCATA

hide sequence

RefSeq Acc Id:

XM_040283356 ⟹ XP_040139290

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024404946	122,018,007 - 122,050,977 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_005329833	(Get FASTA)	NCBI Sequence Viewer
	XP_040139290	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000006061.2
GenBank Protein	KAG3290286	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005329833 ⟸ XM_005329776
- UniProtKB:	I3M8I5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDADSDVALDILITNVVCVFRTRCHLNLRKIALEGANVIYKRDVGKVLMKLRKPRITATIWSSG KIICTGATSEEEAKFGARRLARSLQKLGFQVIFTDFKVVNVLAVCNMPFEIRLPEFTKNNRPHA SYEPELHPAVCYRIKSLRATLQIFSTGSITVTGPNVKAVATAVEQIYPFVFESRKEIL hide sequence

RefSeq Acc Id:	XP_040139290 ⟸ XM_040283356
- UniProtKB:	I3M8I5 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSSTOP00000006061 ⟸ ENSSTOT00000006778

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000006786	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000006778.3	UniProtKB/TrEMBL
Gene3D-CATH	3.30.310.10	UniProtKB/TrEMBL
InterPro	TBP	UniProtKB/TrEMBL
	TBP-like	UniProtKB/TrEMBL
	TBP_dom_sf	UniProtKB/TrEMBL
NCBI Gene	Tbpl1	ENTREZGENE
PANTHER	PTHR10126	UniProtKB/TrEMBL
	TATA BOX-BINDING PROTEIN-LIKE 1	UniProtKB/TrEMBL
Pfam	TBP	UniProtKB/TrEMBL
PRINTS	TIFACTORIID	UniProtKB/TrEMBL
Superfamily-SCOP	TATA-box binding protein-like	UniProtKB/TrEMBL
UniProt	I3M8I5	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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