Arhgap5 (Rho GTPase activating protein 5) - Rat Genome Database

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Gene: Arhgap5 (Rho GTPase activating protein 5) Ictidomys tridecemlineatus
Analyze
Symbol: Arhgap5
Name: Rho GTPase activating protein 5
RGD ID: 12649443
Description: ENCODES a protein that exhibits GTPase activator activity (inferred); SH2 domain binding (inferred); INVOLVED IN cell migration (ortholog); epithelial cell migration (ortholog); mammary gland development (ortholog); ASSOCIATED WITH Brain-Lung-Thyroid Syndrome (ortholog); Experimental Mammary Neoplasms (ortholog); genetic disease (ortholog); FOUND IN cytosol (inferred); endoplasmic reticulum (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: rho GTPase-activating protein 5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864043,056,223 - 43,122,569 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364946,562,069 - 6,623,175 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364946,562,092 - 6,624,015 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Arhgap5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864043,056,223 - 43,122,569 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364946,562,069 - 6,623,175 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364946,562,092 - 6,624,015 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARHGAP5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381432,077,304 - 32,159,728 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1432,076,114 - 32,159,728 (+)EnsemblGRCh38hg38GRCh38
GRCh371432,546,510 - 32,628,934 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361431,616,246 - 31,698,685 (+)NCBINCBI36Build 36hg18NCBI36
Build 341431,616,247 - 31,694,095NCBI
Celera1412,412,908 - 12,495,351 (+)NCBICelera
Cytogenetic Map14q12NCBI
HuRef1412,663,810 - 12,746,250 (+)NCBIHuRef
CHM1_11432,546,410 - 32,628,781 (+)NCBICHM1_1
T2T-CHM13v2.01426,274,927 - 26,357,362 (+)NCBIT2T-CHM13v2.0
Arhgap5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391252,550,555 - 52,618,761 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1252,550,755 - 52,618,758 (+)EnsemblGRCm39 Ensembl
GRCm381252,503,763 - 52,571,978 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1252,503,972 - 52,571,975 (+)EnsemblGRCm38mm10GRCm38
MGSCv371253,617,064 - 53,668,839 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361253,437,697 - 53,489,472 (+)NCBIMGSCv36mm8
Celera1253,816,020 - 53,871,323 (+)NCBICelera
Cytogenetic Map12C1NCBI
cM Map1222.16NCBI
Arhgap5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8675,711,199 - 75,774,636 (+)NCBIGRCr8
mRatBN7.2669,975,904 - 70,039,299 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl669,976,214 - 70,037,660 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx670,400,553 - 70,463,444 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0670,707,197 - 70,770,089 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0670,146,761 - 70,209,656 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0673,345,129 - 73,408,304 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl673,345,392 - 73,405,880 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0682,905,983 - 82,970,518 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4672,685,231 - 72,693,052 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1672,688,353 - 72,735,913 (+)NCBI
Celera668,851,685 - 68,859,506 (+)NCBICelera
Cytogenetic Map6q23NCBI
Arhgap5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540928,627,176 - 28,705,893 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540928,627,176 - 28,682,302 (-)NCBIChiLan1.0ChiLan1.0
ARHGAP5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21533,393,901 - 33,487,196 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11432,610,399 - 32,702,106 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01412,844,042 - 12,934,411 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11431,036,491 - 31,125,349 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1431,036,511 - 31,125,349 (+)Ensemblpanpan1.1panPan2
ARHGAP5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1811,190,663 - 11,269,353 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl811,204,696 - 11,267,086 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha811,052,457 - 11,131,162 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0811,292,865 - 11,371,626 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl811,293,336 - 11,370,667 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1810,977,322 - 11,056,021 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0811,057,909 - 11,136,737 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0811,336,405 - 11,415,092 (+)NCBIUU_Cfam_GSD_1.0
ARHGAP5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl767,494,941 - 67,594,197 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1767,494,237 - 67,631,461 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2772,356,323 - 72,370,515 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARHGAP5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1248,914,485 - 8,986,498 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl248,928,252 - 8,988,302 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606218,559,918 - 18,566,253 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arhgap5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624820305,475 - 381,058 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624820302,000 - 381,043 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000020314   ⟹   ENSSTOP00000022502
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049364946,562,069 - 6,623,175 (+)Ensembl
RefSeq Acc Id: XM_005322665   ⟹   XP_005322722
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864043,056,223 - 43,122,569 (+)NCBI
SpeTri2.0NW_0049364946,562,092 - 6,624,015 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040276021   ⟹   XP_040131955
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440864043,056,223 - 43,122,569 (+)NCBI
Protein Sequences
Protein RefSeqs XP_005322722 (Get FASTA)   NCBI Sequence Viewer  
  XP_040131955 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000022502.1
GenBank Protein KAG3261064 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005322722   ⟸   XM_005322665
- Peptide Label: isoform X1
- UniProtKB: I3NDQ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040131955   ⟸   XM_040276021
- Peptide Label: isoform X2
RefSeq Acc Id: ENSSTOP00000022502   ⟸   ENSSTOT00000020314
Protein Domains
FF   pG1 pseudoGTPase   pG2 pseudoGTPase   Rho-GAP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000020291 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000020314.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.440 UniProtKB/TrEMBL
  1.10.555.10 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro FF_domain UniProtKB/TrEMBL
  FF_domain_sf UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  pG1 UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
  RhoGAP-FF1 UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/TrEMBL
  RhoGAP_pG1_pG2 UniProtKB/TrEMBL
  RhoGAP_pG2 UniProtKB/TrEMBL
NCBI Gene Arhgap5 ENTREZGENE
PANTHER RHO GTPASE-ACTIVATING PROTEIN 190 UniProtKB/TrEMBL
  RHO GTPASE-ACTIVATING PROTEIN 5 UniProtKB/TrEMBL
Pfam PF01846 UniProtKB/TrEMBL
  RhoGAP UniProtKB/TrEMBL
  RhoGAP-FF1 UniProtKB/TrEMBL
  RhoGAP_pG1_pG2 UniProtKB/TrEMBL
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE PG1 UniProtKB/TrEMBL
  PG2 UniProtKB/TrEMBL
  PS51676 UniProtKB/TrEMBL
  RHOGAP UniProtKB/TrEMBL
SMART RhoGAP UniProtKB/TrEMBL
  SM00441 UniProtKB/TrEMBL
Superfamily-SCOP SSF48350 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
  SSF81698 UniProtKB/TrEMBL
UniProt I3NDQ5 ENTREZGENE, UniProtKB/TrEMBL