Prkaca (protein kinase cAMP-activated catalytic subunit alpha) - Rat Genome Database

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Gene: Prkaca (protein kinase cAMP-activated catalytic subunit alpha) Ictidomys tridecemlineatus
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Symbol: Prkaca
Name: protein kinase cAMP-activated catalytic subunit alpha
RGD ID: 12648756
Description: ENCODES a protein that exhibits ATP binding (ortholog); cAMP-dependent protein kinase activity (ortholog); magnesium ion binding (ortholog); INVOLVED IN cellular response to cold (ortholog); cellular response to glucose stimulus (ortholog); cellular response to heat (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH adrenal cortical adenoma (ortholog); Adrenal Gland Neoplasms (ortholog); brain ischemia (ortholog); FOUND IN acrosomal vesicle (ortholog); axoneme (ortholog); cAMP-dependent protein kinase complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: cAMP-dependent protein kinase catalytic subunit alpha
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118207,588,938 - 207,605,559 (+)NCBI
SpeTri2.0NW_0049366592,750,015 - 2,765,914 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
acebutolol pharmacodynamics pathway  (ISO)
adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway  (ISO)
amiodarone pharmacodynamics pathway  (ISO)
amlodipine pharmacodynamics pathway  (ISO)
atenolol pharmacodynamics pathway  (ISO)
betaxolol pharmacodynamics pathway  (ISO)
bisoprolol pharmacodynamics pathway  (ISO)
bupranolol drug pathway  (ISO)
bupranolol pharmacodynamics pathway  (ISO)
carvedilol pharmacodynamics pathway  (ISO)
diltiazem pharmacodynamics pathway  (ISO)
disopyramide pharmacodynamics pathway  (ISO)
dobutamine pharmacodynamics pathway  (ISO)
dopamine signaling pathway  (ISO)
eicosanoid signaling pathway  (ISO)
esmolol pharmacodynamics pathway  (ISO)
flecainde pharmacodynamics pathway  (ISO)
fosphenytoin pharmacodynamics pathway  (ISO)
granulocyte-macrophage colony-stimulating factor signaling pathway  (ISO)
Hedgehog signaling pathway  (ISO)
ibutilide pharmacodynamics pathway  (ISO)
interleukin-3 signaling pathway  (ISO)
isoprenaline pharmacodynamics pathway  (ISO)
isradipine pharmacodynamics pathway  (ISO)
levobunolol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
metoprolol pharmacodynamics pathway  (ISO)
mexiletine pharmacodynamics pathway  (ISO)
nadolol pharmacodynamics pathway  (ISO)
nebivolol pharmacodynamics pathway  (ISO)
nifedipine pharmacodynamics pathway  (ISO)
nimodipine pharmacodynamics pathway  (ISO)
nisoldipine pharmacodynamics pathway  (ISO)
nitrendipine pharmacodynamics pathway  (ISO)
penbutolol pharmacodynamics pathway  (ISO)
phenytoin pharmacodynamics pathway  (ISO)
phosphatidylinositol 3-kinase-Akt signaling pathway  (ISO)
pindolol pharmacodynamics pathway  (ISO)
procainamide pharmacodynamics pathway  (ISO)
propranolol pharmacodynamics pathway  (ISO)
protein kinase A (PKA) signaling pathway  (ISO)
quinidine pharmacodynamics pathway  (ISO)
sotalol pharmacodynamics pathway  (ISO)
syndecan signaling pathway  (ISO)
timolol pharmacodynamics pathway  (ISO)
vascular endothelial growth factor signaling pathway  (ISO)
verapamil pharmacodynamics pathway  (ISO)

References

Genomics

Comparative Map Data
Prkaca
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118207,588,938 - 207,605,559 (+)NCBI
SpeTri2.0NW_0049366592,750,015 - 2,765,914 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRKACA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1914,091,688 - 14,118,084 (-)EnsemblGRCh38hg38GRCh38
GRCh381914,091,688 - 14,117,762 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371914,202,500 - 14,228,574 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361914,063,500 - 14,089,559 (-)NCBINCBI36hg18NCBI36
Build 341914,063,508 - 14,085,992NCBI
Celera1914,096,777 - 14,122,833 (-)NCBI
Cytogenetic Map19p13.12NCBI
HuRef1913,774,379 - 13,800,126 (-)NCBIHuRef
CHM1_11914,202,926 - 14,228,985 (-)NCBICHM1_1
Prkaca
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39884,699,607 - 84,723,073 (+)NCBIGRCm39mm39
GRCm39 Ensembl884,699,622 - 84,723,072 (+)Ensembl
GRCm38883,972,978 - 83,996,444 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl883,972,993 - 83,996,443 (+)EnsemblGRCm38mm10GRCm38
MGSCv37886,496,877 - 86,520,344 (+)NCBIGRCm37mm9NCBIm37
MGSCv36886,863,093 - 86,886,544 (+)NCBImm8
Celera888,266,474 - 88,289,645 (+)NCBICelera
Cytogenetic Map8C2NCBI
Prkaca
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21924,155,081 - 24,178,430 (-)NCBI
Rnor_6.0 Ensembl1925,095,089 - 25,118,860 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01925,095,089 - 25,118,869 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01936,073,104 - 36,096,884 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41925,840,795 - 25,864,786 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11925,845,620 - 25,861,927 (-)NCBI
Celera1923,703,180 - 23,726,723 (-)NCBICelera
Cytogenetic Map19q11NCBI
Prkaca
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541532,793,718 - 32,812,930 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541532,794,172 - 32,807,944 (-)NCBIChiLan1.0ChiLan1.0
PRKACA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11914,385,183 - 14,406,205 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1914,385,191 - 14,406,205 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01913,657,344 - 13,683,864 (-)NCBIMhudiblu_PPA_v0panPan3
PRKACA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12048,416,730 - 48,425,237 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2048,409,045 - 48,426,669 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2048,283,546 - 48,299,768 (+)NCBI
ROS_Cfam_1.02048,926,811 - 48,944,065 (+)NCBI
UMICH_Zoey_3.12048,138,017 - 48,154,228 (+)NCBI
UNSW_CanFamBas_1.02048,564,570 - 48,580,793 (+)NCBI
UU_Cfam_GSD_1.02048,807,387 - 48,823,603 (+)NCBI
PRKACA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl265,074,870 - 65,095,553 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1265,074,876 - 65,095,564 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2265,350,544 - 65,371,236 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PRKACA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1612,743,752 - 12,759,155 (-)NCBI
Vero_WHO_p1.0NW_0236660746,888,080 - 6,914,845 (+)NCBI
Prkaca
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249011,319,426 - 1,336,848 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_013363261   ⟹   XP_013218715
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0NW_0049366592,750,015 - 2,765,914 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040290990   ⟹   XP_040146924
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118207,588,938 - 207,605,559 (+)NCBI
Protein Sequences
Protein RefSeqs XP_040146924 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_013218715   ⟸   XM_013363261
- Sequence:
RefSeq Acc Id: XP_040146924   ⟸   XM_040290990

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000002327 ENTREZGENE
NCBI Gene Prkaca ENTREZGENE