Derl2 (derlin 2) - Rat Genome Database

Name: Derl2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Derl2 (derlin 2) Ictidomys tridecemlineatus

Analyze

Symbol:

Derl2

Name:

derlin 2

RGD ID:

12646916

Description:

ENCODES a protein that exhibits misfolded protein binding (inferred); protein-containing complex binding (inferred); signal recognition particle binding (inferred); INVOLVED IN retrograde protein transport, ER to cytosol (ortholog); suckling behavior (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy 25 (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

derlin 2, transcript variant X1; derlin 2, transcript variant X2; derlin 2, transcript variant X3; derlin 2, transcript variant X4; derlin 2, transcript variant X5; derlin-2

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	DERL2 (derlin 2)	NCBI	Ortholog
Mus musculus (house mouse):	Derl2 (Der1-like domain family, member 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Derl2 (derlin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Derl2 (derlin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	DERL2 (derlin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	DERL2 (derlin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	DERL2 (derlin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	DERL2 (derlin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Derl2 (derlin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	53,558,913 - 53,572,084 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936677	2,328,904 - 2,342,080 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936677	2,328,783 - 2,342,068 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

developmental and epileptic encephalopathy 25 (ISO)

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

endoplasmic reticulum unfolded protein response (IEA)

ERAD pathway (IEA)

negative regulation of retrograde protein transport, ER to cytosol (IEA)

positive regulation of cell growth (IEA)

positive regulation of cell population proliferation (IEA)

proteasomal protein catabolic process (IEA)

response to stress (IEA)

retrograde protein transport, ER to cytosol (IEA,ISO)

suckling behavior (IEA,ISO)

Cellular Component

cytoplasm (ISO)

early endosome (IEA)

endoplasmic reticulum (IEA)

endoplasmic reticulum membrane (IEA)

Hrd1p ubiquitin ligase ERAD-L complex (IEA)

late endosome (IEA)

membrane (IEA)

Molecular Function

misfolded protein binding (IEA)

protein binding (ISO)

protein-containing complex binding (IEA)

signal recognition particle binding (IEA)

ubiquitin-specific protease binding (IEA)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Derl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	53,558,913 - 53,572,084 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936677	2,328,904 - 2,342,080 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936677	2,328,783 - 2,342,068 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DERL2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	5,471,254 - 5,486,817 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	5,471,254 - 5,486,811 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	5,374,574 - 5,389,498 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	5,318,337 - 5,330,221 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	5,318,336 - 5,330,218	NCBI
Celera	17	5,393,985 - 5,405,873 (-)	NCBI		Celera
Cytogenetic Map	17	p13.2	NCBI
HuRef	17	5,268,081 - 5,279,745 (-)	NCBI		HuRef
CHM1_1	17	5,387,294 - 5,399,165 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	17	5,364,997 - 5,380,235 (-)	NCBI		T2T-CHM13v2.0

Derl2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	70,898,266 - 70,910,667 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	70,897,990 - 70,910,667 (-)	Ensembl		GRCm39 Ensembl
GRCm38	11	71,007,440 - 71,019,841 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	71,007,164 - 71,019,841 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	70,820,947 - 70,832,765 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	70,823,640 - 70,835,458 (-)	NCBI		MGSCv36	mm8
Celera	11	78,561,860 - 78,573,678 (-)	NCBI		Celera
Cytogenetic Map	11	B4	NCBI
cM Map	11	43.21	NCBI

Derl2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	56,226,340 - 56,238,038 (-)	NCBI		GRCr8
mRatBN7.2	10	55,727,764 - 55,739,442 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	55,727,643 - 55,739,518 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	60,407,453 - 60,419,059 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	59,895,972 - 59,907,578 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	55,395,062 - 55,406,668 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	57,641,682 - 57,653,554 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	57,644,207 - 57,653,359 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	57,386,894 - 57,398,868 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	10	54,873,447 - 54,885,319 (-)	NCBI		Celera
Cytogenetic Map	10	q24	NCBI

Derl2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955467	10,825,341 - 10,837,328 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955467	10,824,922 - 10,837,408 (-)	NCBI	ChiLan1.0	ChiLan1.0

DERL2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	13,084,405 - 13,096,337 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	15,049,592 - 15,064,585 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	5,519,183 - 5,534,145 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	5,514,440 - 5,526,363 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	5,514,440 - 5,526,363 (-)	Ensembl	panpan1.1		panPan2

DERL2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	31,319,660 - 31,330,846 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	31,319,717 - 31,330,841 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	31,457,816 - 31,468,997 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	31,424,427 - 31,435,599 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	31,424,475 - 31,435,594 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	31,389,973 - 31,401,157 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	31,348,892 - 31,360,075 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	31,525,284 - 31,536,488 (+)	NCBI		UU_Cfam_GSD_1.0

DERL2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	51,507,996 - 51,524,793 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	51,508,138 - 51,524,799 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

DERL2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	4,882,296 - 4,897,799 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	4,881,876 - 4,898,078 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666059	16,689,748 - 16,705,481 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Derl2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624786	9,274,302 - 9,285,288 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624786	9,274,302 - 9,285,645 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005337335	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013363811	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021734588	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021734590	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021734591	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000662	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000020753 ⟹ ENSSTOP00000016872

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936677	2,328,904 - 2,342,080 (+)	Ensembl

RefSeq Acc Id:

XM_005337335 ⟹ XP_005337392

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405602	53,558,913 - 53,572,084 (-)	NCBI
SpeTri2.0	NW_004936677	2,328,893 - 2,342,068 (+)	NCBI

Sequence:

show sequence

TACTGGCGGAAGGGGAAGTTGGGGGGTGGGCAGGCGGCGGTGGGAAAGATGGCGTACCAGAGCC
TCCGGCTGGAGTATCTGCAAATCCCACCGGTTAGCCGCGCCTACACCACCGCCTGCGTCCTCAC
CACCGCCGCTGTGCAGCTGGAATTGATCACACCTTTTCAGCTGTACTTCAATCCTGAATTAATT
TTTAAACACTTTCAAATATGGAGGTTAATCACCAATTTCTTATTTTTTGGACCAGTTGGATTCA
ATTTTTTATTTAACATGATTTTTCTATATCGTTACTGTCGAATGCTAGAAGAAGGCTCCTTCCG
AGGTCGGACAGCAGACTTTGTATTTATGTTCCTTTTTGGTGGATTCTTAATGACTCTTTTTGGT
TTGTTTGTGAGCTTAGTTTTCTTGGGACAGGCCTTTACAATAATGCTCGTCTATGTATGGAGCC
GAAGGAACCCATATGTCCGCATGAACTTCTTTGGTCTTCTCAACTTCCAGGCCCCTTTTCTGCC
CTGGGTGCTCATGGGGTTTTCCTTGTTGTTGGGGAACTCGATCATTGTGGACCTCTTGGGTATT
GCAGTTGGACACATATATTTTTTCTTGGAAGATGTATTTCCCAATCAGCCTGGAGGGATAAGAA
TTCTGAAAACACCATCTATTTTGAGGACTATTTTTGATACACCAGATGAGGATCCAAATTACAA
TCCACTACCTGAAGAACGGCCAGGAGGCTTTGCCTGGGGTGAGGGCCAACGTCTCGGAGGTTAA
AGCAGCCGTGCCAATAATGAAACCCAGCTGGGAAGGACTTGGTGAAATACCCATTGGGATTCTT
TTATCCTTTGTTGCAAAAGTGTGGACACTTTTGACAGCTTGACAGATTTTAACTCCAGAAGCAC
TTTATGAAATGGTACACTGACTAATCCAGAAGACATTTCCAGCAGTTTGCCAGTGGTTCCTCAC
TACACTGGTACTGAAAGTGTAATCTCTTGGAGCCAAAAAACTGGAGAAAGATATCCTGCTGCCT
CTAACAAGTACATAAGTACTTGAATTCTGTGGCATAAGGCAGGGCTTTTTCTTCTTCTTCTTTG
ATAGACGAGGCCATGGTGTAAATGAAAGTTTCAGAGAGGACAAAATAAAACTGAGTTCCATCTC
TCTTTCACTGTATTAAAGCTTTTGTGTGTGATCTTTTTAAATTATGATAGTGTATGCTAGTTCT
CCCAAGTAGGTCTGGACTGAGCAGTTTACAGGCCTGCTCTTCCTGTGTCTTTACAGCTTTCAAA
TGGATTTCATTTCAAGATTGAAAACATGACTATAATGCTGTAGCTGTGTACATCTTACTAATTC
AGAGTGCTAGCTTCAGTAGAAAAATTTATTTCTGTCATTCAGATAGCTTGTTTTCCATCTGGGA
ATTGCAAAACTTCAAGTCATCAGAACACAAGAAAGAGAAGGGAGGGTGGTTCTTGTAGCAGAAA
TTCAGCTGTAGAATTGTCAGCTGTAAGTAAAAGGCTCATGTGGTATCTTATTTATTCTGCTTGC
TTTTTTCCATTAAGAACTATCCAGGGAGTGACTGGTAATGGCCACATTTTTTGAAAACTATGGG
AAGATGAATGAGTAGCAGCTAGACATACTTTCCTCCTGGGTCATTGGCTGGTTAATATTTGTCA
TTTACTTCATGAAAAGTTGAAAACCTTTTCAGAGCCAAGTAAATGGTTACCTTCCCAATTAGGC
AGAAATTAGGGTCCACAGAAGCAGGCCTTTAAATCATGCCTGTAGTTCAACAAATACTTGTCCA
AAATAGTAAGTTCTTCCCGAATCCCAGCAGGTTTGTGTTCATACTGCTTAATCAGAACTCAGGA
AAGTAAAAGAGTACACCCCTAAGAAAGAAATGATCTCAGTTTTTTATGAATAGCATGTAGGTAC
AAGAGCCTGTCCCCCAACTGGATTGTCTTCAGTTTTGTCTTGGTTAGGGATAGCTTTACAGAGT
GAGATTTCCTCAGATTGACATAGGCTTAGATCAAACAAAAAAAATCTTAAGTGGGAATTTTCAG
ATTATTGTTAAAGTACAAAGTATTTTAATGTCTTTAAAATTGGAATATGCATAAGTATGGAATT
TCGTACGCGTATTTTACACGTTGCTAGTAAGTAACTTTGAATATGATTGTTGCAGTTTTATGGA
ATTTGGGTCAATAGGACTGCTTTTTCTTCTAAGCAGTTTAAGAAGTGTTTTTAAAGTTTAAATG
CCATACTTAGATTGTATAATCCTTACAGGATTCTTAAATTTAATCATCTTTGTCTTTATCTAGA
AAGTTTTACCAATGACTTTTAGTAGTTTTTTTTGTTTGTTTGCTTTGGGGCTAGAAATGGGTTT
CTCTAGTTTTATTTGTTCTCCTTGACTTAATTTTGGGTTATCCAATTAATGGAATTTTTGTGGT
AAAATTTTAATCCTAAAATCTATTCACTGACTTTTCATTTAATTAGGGAGTATCTGTACACATT
CGTGACTGGGTAAAACAGGAAACACATTTTGAATGTATAGCCTAAAGGCAGTCATTTATAGGAT
TTTGTTTCTCTGCTTTTGTAGGGTATAAATTCCTAGTGGCAGGATGCCCTGCTGTGCTACTACA
CTGTGTCCTTGGCAGTGGTGATTTAAATCACTGACCTCTTATCAGTTTGGCCAGTCCCACTCCC
ACTCATCCCCAGCCCTGTGTTGCTTGACAGGATCCCCAGGCTTACCTGAACCTAAGGAAAAGTC
CTTACTTCTTCCCCAGCTTACCTCTTGATCTTGAGTCTTCCAGAACATTTCCTTTTCATAATGC
AAGTCAATTGAAAAGTGAGATTTGATATATGGAATTTTTGTGACCTTTCAACCTTACATACATA
TAATTTGAAAGATTCCTGAATTTTACTAGTTATACTGAAAAGCACACACCTGATTAAAACATGT
TTTTTTGTTACAGAAATACAATATATGTTCATTTGAAAATAAATGGACGAGCAAATTGCATCTC
CCTAGGAGATACATTTTATATACATTTTGGTGTGTTTTTTCACTATGGATTTCTATTTGTTTCT
CTCTTCCACTTGGTTCTTTTTTTTTTTTTTTTTCTGTGTCACTATTGTATGTCCTAATATCTTT
CATACTTCTGTATTCTCTCAAAGCAAAGCACCTTTGTCCTGGATCTTGTTAAGGAAAGCCTCAC
TCAGTCTCTCTGGGCTTCTGAAAATTAGGAAATATGAGAGTATTCTGTGTTGAGTAACTGGCTT
TCTAGAATTGTCATCTCTCCTGCCAGTGTTTTAAGTCATGGTTCTGTTTTCCTTTGACAGGTGA
GTTTCATCTTTGGTGTTAGCTAAGATCCTGTCATGATTTTTAGTGCTCTGCAGGATGCCCCTAA
ATTACTTACATATTTTATGAGTTTTCATTAAAGTTGTCGAACCTTATATGGTCAAGTTACTTAC
CTGCTCAAAAATCCAGTGAATTCTTAGCCCCTATATTAAATGCATACTTTTTGTCTTCTGAACC
TTATTCCCACTTCTACCTAACAGGGACCTCAAGTTAAGCCTCTCTAATCCTTCAAGGCCTGGAC
TTGTTCCTGACACCTCAAGAAATCTTGATTCTAAGGCCTATTTCATTGTCTTCTTTGAATCTCT
ATAAAGCTTCAAATTCTGTATGACATATTCTTACACCAAATTATATATTGTCTTGTACTGTTCC
TAGCTGGTACATGTATATTAGTCTTGTCTCCCTCATGAGAATGTAAGCTCCTTAAGGGCAGGGA
CCATGTCTTAATTTTTGTATCCACCACAGTGCCTAGCACAGTGCTTGGCACATGGGTGCTGAAT
AAATACTTTGTTTATTAATCAGCAAAC

hide sequence

RefSeq Acc Id:

XM_013363811 ⟹ XP_013219265

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405602	53,558,913 - 53,572,080 (-)	NCBI
SpeTri2.0	NW_004936677	2,328,894 - 2,342,068 (+)	NCBI

Sequence:

show sequence

ACTGGCGGAAGGGGAAGTTGGGGGGTGGGCAGGCGGCGGTGGGAAAGATGGCGTACCAGAGCCT
CCGGCTGGAGTATCTGCAAATCCCACCGGTTAGCCGCGCCTACACCACCGCCTGCGTCCTCACC
ACCGCCGCTGTGCTGGAATTGATCACACCTTTTCAGCTGTACTTCAATCCTGAATTAATTTTTA
AACACTTTCAAATATGGAGGTTAATCACCAATTTCTTATTTTTTGGACCAGTTGGATTCAATTT
TTTATTTAACATGATTTTTCTATATCGTTACTGTCGAATGCTAGAAGAAGGCTCCTTCCGAGGT
CGGACAGCAGACTTTGTATTTATGTTCCTTTTTGGTGGATTCTTAATGACTCTTTTTGGTTTGT
TTGTGAGCTTAGTTTTCTTGGGACAGGCCTTTACAATAATGCTCGTCTATGTATGGAGCCGAAG
GAACCCATATGTCCGCATGAACTTCTTTGGTCTTCTCAACTTCCAGGCCCCTTTTCTGCCCTGG
GTGCTCATGGGGTTTTCCTTGTTGTTGGGGAACTCGATCATTGTGGACCTCTTGGGTATTGCAG
TTGGACACATATATTTTTTCTTGGAAGATGTATTTCCCAATCAGCCTGGAGGGATAAGAATTCT
GAAAACACCATCTATTTTGAGGACTATTTTTGATACACCAGATGAGGATCCAAATTACAATCCA
CTACCTGAAGAACGGCCAGGAGGCTTTGCCTGGGGTGAGGGCCAACGTCTCGGAGGTTAAAGCA
GCCGTGCCAATAATGAAACCCAGCTGGGAAGGACTTGGTGAAATACCCATTGGGATTCTTTTAT
CCTTTGTTGCAAAAGTGTGGACACTTTTGACAGCTTGACAGATTTTAACTCCAGAAGCACTTTA
TGAAATGGTACACTGACTAATCCAGAAGACATTTCCAGCAGTTTGCCAGTGGTTCCTCACTACA
CTGGTACTGAAAGTGTAATCTCTTGGAGCCAAAAAACTGGAGAAAGATATCCTGCTGCCTCTAA
CAAGTACATAAGTACTTGAATTCTGTGGCATAAGGCAGGGCTTTTTCTTCTTCTTCTTTGATAG
ACGAGGCCATGGTGTAAATGAAAGTTTCAGAGAGGACAAAATAAAACTGAGTTCCATCTCTCTT
TCACTGTATTAAAGCTTTTGTGTGTGATCTTTTTAAATTATGATAGTGTATGCTAGTTCTCCCA
AGTAGGTCTGGACTGAGCAGTTTACAGGCCTGCTCTTCCTGTGTCTTTACAGCTTTCAAATGGA
TTTCATTTCAAGATTGAAAACATGACTATAATGCTGTAGCTGTGTACATCTTACTAATTCAGAG
TGCTAGCTTCAGTAGAAAAATTTATTTCTGTCATTCAGATAGCTTGTTTTCCATCTGGGAATTG
CAAAACTTCAAGTCATCAGAACACAAGAAAGAGAAGGGAGGGTGGTTCTTGTAGCAGAAATTCA
GCTGTAGAATTGTCAGCTGTAAGTAAAAGGCTCATGTGGTATCTTATTTATTCTGCTTGCTTTT
TTCCATTAAGAACTATCCAGGGAGTGACTGGTAATGGCCACATTTTTTGAAAACTATGGGAAGA
TGAATGAGTAGCAGCTAGACATACTTTCCTCCTGGGTCATTGGCTGGTTAATATTTGTCATTTA
CTTCATGAAAAGTTGAAAACCTTTTCAGAGCCAAGTAAATGGTTACCTTCCCAATTAGGCAGAA
ATTAGGGTCCACAGAAGCAGGCCTTTAAATCATGCCTGTAGTTCAACAAATACTTGTCCAAAAT
AGTAAGTTCTTCCCGAATCCCAGCAGGTTTGTGTTCATACTGCTTAATCAGAACTCAGGAAAGT
AAAAGAGTACACCCCTAAGAAAGAAATGATCTCAGTTTTTTATGAATAGCATGTAGGTACAAGA
GCCTGTCCCCCAACTGGATTGTCTTCAGTTTTGTCTTGGTTAGGGATAGCTTTACAGAGTGAGA
TTTCCTCAGATTGACATAGGCTTAGATCAAACAAAAAAAATCTTAAGTGGGAATTTTCAGATTA
TTGTTAAAGTACAAAGTATTTTAATGTCTTTAAAATTGGAATATGCATAAGTATGGAATTTCGT
ACGCGTATTTTACACGTTGCTAGTAAGTAACTTTGAATATGATTGTTGCAGTTTTATGGAATTT
GGGTCAATAGGACTGCTTTTTCTTCTAAGCAGTTTAAGAAGTGTTTTTAAAGTTTAAATGCCAT
ACTTAGATTGTATAATCCTTACAGGATTCTTAAATTTAATCATCTTTGTCTTTATCTAGAAAGT
TTTACCAATGACTTTTAGTAGTTTTTTTTGTTTGTTTGCTTTGGGGCTAGAAATGGGTTTCTCT
AGTTTTATTTGTTCTCCTTGACTTAATTTTGGGTTATCCAATTAATGGAATTTTTGTGGTAAAA
TTTTAATCCTAAAATCTATTCACTGACTTTTCATTTAATTAGGGAGTATCTGTACACATTCGTG
ACTGGGTAAAACAGGAAACACATTTTGAATGTATAGCCTAAAGGCAGTCATTTATAGGATTTTG
TTTCTCTGCTTTTGTAGGGTATAAATTCCTAGTGGCAGGATGCCCTGCTGTGCTACTACACTGT
GTCCTTGGCAGTGGTGATTTAAATCACTGACCTCTTATCAGTTTGGCCAGTCCCACTCCCACTC
ATCCCCAGCCCTGTGTTGCTTGACAGGATCCCCAGGCTTACCTGAACCTAAGGAAAAGTCCTTA
CTTCTTCCCCAGCTTACCTCTTGATCTTGAGTCTTCCAGAACATTTCCTTTTCATAATGCAAGT
CAATTGAAAAGTGAGATTTGATATATGGAATTTTTGTGACCTTTCAACCTTACATACATATAAT
TTGAAAGATTCCTGAATTTTACTAGTTATACTGAAAAGCACACACCTGATTAAAACATGTTTTT
TTGTTACAGAAATACAATATATGTTCATTTGAAAATAAATGGACGAGCAAATTGCATCTCCCTA
GGAGATACATTTTATATACATTTTGGTGTGTTTTTTCACTATGGATTTCTATTTGTTTCTCTCT
TCCACTTGGTTCTTTTTTTTTTTTTTTTTCTGTGTCACTATTGTATGTCCTAATATCTTTCATA
CTTCTGTATTCTCTCAAAGCAAAGCACCTTTGTCCTGGATCTTGTTAAGGAAAGCCTCACTCAG
TCTCTCTGGGCTTCTGAAAATTAGGAAATATGAGAGTATTCTGTGTTGAGTAACTGGCTTTCTA
GAATTGTCATCTCTCCTGCCAGTGTTTTAAGTCATGGTTCTGTTTTCCTTTGACAGGTGAGTTT
CATCTTTGGTGTTAGCTAAGATCCTGTCATGATTTTTAGTGCTCTGCAGGATGCCCCTAAATTA
CTTACATATTTTATGAGTTTTCATTAAAGTTGTCGAACCTTATATGGTCAAGTTACTTACCTGC
TCAAAAATCCAGTGAATTCTTAGCCCCTATATTAAATGCATACTTTTTGTCTTCTGAACCTTAT
TCCCACTTCTACCTAACAGGGACCTCAAGTTAAGCCTCTCTAATCCTTCAAGGCCTGGACTTGT
TCCTGACACCTCAAGAAATCTTGATTCTAAGGCCTATTTCATTGTCTTCTTTGAATCTCTATAA
AGCTTCAAATTCTGTATGACATATTCTTACACCAAATTATATATTGTCTTGTACTGTTCCTAGC
TGGTACATGTATATTAGTCTTGTCTCCCTCATGAGAATGTAAGCTCCTTAAGGGCAGGGACCAT
GTCTTAATTTTTGTATCCACCACAGTGCCTAGCACAGTGCTTGGCACATGGGTGCTGAATAAAT
ACTTTGTTTATTAATCAGCAAAC

hide sequence

RefSeq Acc Id:

XM_021734588 ⟹ XP_021590263

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405602	53,558,913 - 53,571,907 (-)	NCBI
SpeTri2.0	NW_004936677	2,329,054 - 2,342,068 (+)	NCBI

Sequence:

show sequence

CTTCTCCTTTTCTGGGCTGGATATGACTGGTTCTTCAGGAAACTGGGGTTGGGCCTCGAGGAAG
CCCAGAGGGTCTGGTCCCAGGGCAGCTGGAATTGATCACACCTTTTCAGCTGTACTTCAATCCT
GAATTAATTTTTAAACACTTTCAAATATGGAGGTTAATCACCAATTTCTTATTTTTTGGACCAG
TTGGATTCAATTTTTTATTTAACATGATTTTTCTATATCGTTACTGTCGAATGCTAGAAGAAGG
CTCCTTCCGAGGTCGGACAGCAGACTTTGTATTTATGTTCCTTTTTGGTGGATTCTTAATGACT
CTTTTTGGTTTGTTTGTGAGCTTAGTTTTCTTGGGACAGGCCTTTACAATAATGCTCGTCTATG
TATGGAGCCGAAGGAACCCATATGTCCGCATGAACTTCTTTGGTCTTCTCAACTTCCAGGCCCC
TTTTCTGCCCTGGGTGCTCATGGGGTTTTCCTTGTTGTTGGGGAACTCGATCATTGTGGACCTC
TTGGGTATTGCAGTTGGACACATATATTTTTTCTTGGAAGATGTATTTCCCAATCAGCCTGGAG
GGATAAGAATTCTGAAAACACCATCTATTTTGAGGACTATTTTTGATACACCAGATGAGGATCC
AAATTACAATCCACTACCTGAAGAACGGCCAGGAGGCTTTGCCTGGGGTGAGGGCCAACGTCTC
GGAGGTTAAAGCAGCCGTGCCAATAATGAAACCCAGCTGGGAAGGACTTGGTGAAATACCCATT
GGGATTCTTTTATCCTTTGTTGCAAAAGTGTGGACACTTTTGACAGCTTGACAGATTTTAACTC
CAGAAGCACTTTATGAAATGGTACACTGACTAATCCAGAAGACATTTCCAGCAGTTTGCCAGTG
GTTCCTCACTACACTGGTACTGAAAGTGTAATCTCTTGGAGCCAAAAAACTGGAGAAAGATATC
CTGCTGCCTCTAACAAGTACATAAGTACTTGAATTCTGTGGCATAAGGCAGGGCTTTTTCTTCT
TCTTCTTTGATAGACGAGGCCATGGTGTAAATGAAAGTTTCAGAGAGGACAAAATAAAACTGAG
TTCCATCTCTCTTTCACTGTATTAAAGCTTTTGTGTGTGATCTTTTTAAATTATGATAGTGTAT
GCTAGTTCTCCCAAGTAGGTCTGGACTGAGCAGTTTACAGGCCTGCTCTTCCTGTGTCTTTACA
GCTTTCAAATGGATTTCATTTCAAGATTGAAAACATGACTATAATGCTGTAGCTGTGTACATCT
TACTAATTCAGAGTGCTAGCTTCAGTAGAAAAATTTATTTCTGTCATTCAGATAGCTTGTTTTC
CATCTGGGAATTGCAAAACTTCAAGTCATCAGAACACAAGAAAGAGAAGGGAGGGTGGTTCTTG
TAGCAGAAATTCAGCTGTAGAATTGTCAGCTGTAAGTAAAAGGCTCATGTGGTATCTTATTTAT
TCTGCTTGCTTTTTTCCATTAAGAACTATCCAGGGAGTGACTGGTAATGGCCACATTTTTTGAA
AACTATGGGAAGATGAATGAGTAGCAGCTAGACATACTTTCCTCCTGGGTCATTGGCTGGTTAA
TATTTGTCATTTACTTCATGAAAAGTTGAAAACCTTTTCAGAGCCAAGTAAATGGTTACCTTCC
CAATTAGGCAGAAATTAGGGTCCACAGAAGCAGGCCTTTAAATCATGCCTGTAGTTCAACAAAT
ACTTGTCCAAAATAGTAAGTTCTTCCCGAATCCCAGCAGGTTTGTGTTCATACTGCTTAATCAG
AACTCAGGAAAGTAAAAGAGTACACCCCTAAGAAAGAAATGATCTCAGTTTTTTATGAATAGCA
TGTAGGTACAAGAGCCTGTCCCCCAACTGGATTGTCTTCAGTTTTGTCTTGGTTAGGGATAGCT
TTACAGAGTGAGATTTCCTCAGATTGACATAGGCTTAGATCAAACAAAAAAAATCTTAAGTGGG
AATTTTCAGATTATTGTTAAAGTACAAAGTATTTTAATGTCTTTAAAATTGGAATATGCATAAG
TATGGAATTTCGTACGCGTATTTTACACGTTGCTAGTAAGTAACTTTGAATATGATTGTTGCAG
TTTTATGGAATTTGGGTCAATAGGACTGCTTTTTCTTCTAAGCAGTTTAAGAAGTGTTTTTAAA
GTTTAAATGCCATACTTAGATTGTATAATCCTTACAGGATTCTTAAATTTAATCATCTTTGTCT
TTATCTAGAAAGTTTTACCAATGACTTTTAGTAGTTTTTTTTGTTTGTTTGCTTTGGGGCTAGA
AATGGGTTTCTCTAGTTTTATTTGTTCTCCTTGACTTAATTTTGGGTTATCCAATTAATGGAAT
TTTTGTGGTAAAATTTTAATCCTAAAATCTATTCACTGACTTTTCATTTAATTAGGGAGTATCT
GTACACATTCGTGACTGGGTAAAACAGGAAACACATTTTGAATGTATAGCCTAAAGGCAGTCAT
TTATAGGATTTTGTTTCTCTGCTTTTGTAGGGTATAAATTCCTAGTGGCAGGATGCCCTGCTGT
GCTACTACACTGTGTCCTTGGCAGTGGTGATTTAAATCACTGACCTCTTATCAGTTTGGCCAGT
CCCACTCCCACTCATCCCCAGCCCTGTGTTGCTTGACAGGATCCCCAGGCTTACCTGAACCTAA
GGAAAAGTCCTTACTTCTTCCCCAGCTTACCTCTTGATCTTGAGTCTTCCAGAACATTTCCTTT
TCATAATGCAAGTCAATTGAAAAGTGAGATTTGATATATGGAATTTTTGTGACCTTTCAACCTT
ACATACATATAATTTGAAAGATTCCTGAATTTTACTAGTTATACTGAAAAGCACACACCTGATT
AAAACATGTTTTTTTGTTACAGAAATACAATATATGTTCATTTGAAAATAAATGGACGAGCAAA
TTGCATCTCCCTAGGAGATACATTTTATATACATTTTGGTGTGTTTTTTCACTATGGATTTCTA
TTTGTTTCTCTCTTCCACTTGGTTCTTTTTTTTTTTTTTTTTCTGTGTCACTATTGTATGTCCT
AATATCTTTCATACTTCTGTATTCTCTCAAAGCAAAGCACCTTTGTCCTGGATCTTGTTAAGGA
AAGCCTCACTCAGTCTCTCTGGGCTTCTGAAAATTAGGAAATATGAGAGTATTCTGTGTTGAGT
AACTGGCTTTCTAGAATTGTCATCTCTCCTGCCAGTGTTTTAAGTCATGGTTCTGTTTTCCTTT
GACAGGTGAGTTTCATCTTTGGTGTTAGCTAAGATCCTGTCATGATTTTTAGTGCTCTGCAGGA
TGCCCCTAAATTACTTACATATTTTATGAGTTTTCATTAAAGTTGTCGAACCTTATATGGTCAA
GTTACTTACCTGCTCAAAAATCCAGTGAATTCTTAGCCCCTATATTAAATGCATACTTTTTGTC
TTCTGAACCTTATTCCCACTTCTACCTAACAGGGACCTCAAGTTAAGCCTCTCTAATCCTTCAA
GGCCTGGACTTGTTCCTGACACCTCAAGAAATCTTGATTCTAAGGCCTATTTCATTGTCTTCTT
TGAATCTCTATAAAGCTTCAAATTCTGTATGACATATTCTTACACCAAATTATATATTGTCTTG
TACTGTTCCTAGCTGGTACATGTATATTAGTCTTGTCTCCCTCATGAGAATGTAAGCTCCTTAA
GGGCAGGGACCATGTCTTAATTTTTGTATCCACCACAGTGCCTAGCACAGTGCTTGGCACATGG
GTGCTGAATAAATACTTTGTTTATTAATCAGCAAAC

hide sequence

Protein Sequences


Protein RefSeqs	XP_005337392	(Get FASTA)	NCBI Sequence Viewer
	XP_013219265	(Get FASTA)	NCBI Sequence Viewer
	XP_021590263	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000016872.1
GenBank Protein	KAG3270103	(Get FASTA)	NCBI Sequence Viewer
	KAG3270104	(Get FASTA)	NCBI Sequence Viewer
	KAG3270105	(Get FASTA)	NCBI Sequence Viewer
	KAG3270106	(Get FASTA)	NCBI Sequence Viewer
	KAG3270107	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005337392 ⟸ XM_005337335
- Peptide Label:	isoform X1
- UniProtKB:	I3MXM7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITNFLFF GPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFLGQAFTIML VYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLEDVFPNQ PGGIRILKTPSILRTIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG hide sequence

RefSeq Acc Id:

XP_013219265 ⟸ XM_013363811

- Peptide Label:

isoform X2

- Sequence:

show sequence

MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVLELITPFQLYFNPELIFKHFQIWRLITNFLFFG
PVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFLGQAFTIMLV
YVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLEDVFPNQP
GGIRILKTPSILRTIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG

hide sequence

RefSeq Acc Id:	XP_021590263 ⟸ XM_021734588
- Peptide Label:	isoform X3
- Sequence:	show sequence MIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFLGQAFTIMLVYVWSRRNPY VRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLEDVFPNQPGGIRILKTP SILRTIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG hide sequence

RefSeq Acc Id:

ENSSTOP00000016872 ⟸ ENSSTOT00000020753

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000020586	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000020753.2	UniProtKB/TrEMBL
InterPro	DER1	UniProtKB/TrEMBL
	Rhomboid-like_sf	UniProtKB/TrEMBL
NCBI Gene	Derl2	ENTREZGENE
PANTHER	DER1-LIKE PROTEIN, DERLIN	UniProtKB/TrEMBL
	DERLIN-2	UniProtKB/TrEMBL
Pfam	DER1	UniProtKB/TrEMBL
Superfamily-SCOP	SSF144091	UniProtKB/TrEMBL
UniProt	I3MXM7	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar