Eif5a (eukaryotic translation initiation factor 5A) - Rat Genome Database

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Gene: Eif5a (eukaryotic translation initiation factor 5A) Ictidomys tridecemlineatus
Analyze
Symbol: Eif5a
Name: eukaryotic translation initiation factor 5A
RGD ID: 12642876
Description: ENCODES a protein that exhibits U6 snRNA binding (ortholog); INVOLVED IN cellular response to thyroid hormone stimulus (ortholog); cellular response to virus (ortholog); negative regulation of apoptotic process (ortholog); ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); colorectal cancer (ortholog); FOUND IN annulate lamellae (ortholog); dendrite (ortholog); neuronal cell body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: eukaryotic translation initiation factor 5A, transcript variant X1; eukaryotic translation initiation factor 5A, transcript variant X2; eukaryotic translation initiation factor 5A-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560247,129,875 - 47,134,887 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936595604,268 - 609,075 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Eif5a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560247,129,875 - 47,134,887 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936595604,268 - 609,075 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EIF5A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38177,306,999 - 7,312,463 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl177,306,999 - 7,312,463 (+)EnsemblGRCh38hg38GRCh38
GRCh37177,210,318 - 7,215,782 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36177,151,693 - 7,156,498 (+)NCBINCBI36Build 36hg18NCBI36
Build 34177,151,692 - 7,156,496NCBI
Celera177,236,257 - 7,241,723 (+)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef177,104,783 - 7,109,831 (+)NCBIHuRef
CHM1_1177,219,093 - 7,224,550 (+)NCBICHM1_1
T2T-CHM13v2.0177,210,983 - 7,216,447 (+)NCBIT2T-CHM13v2.0
Eif5a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391169,807,538 - 69,812,784 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1169,807,540 - 69,812,784 (-)EnsemblGRCm39 Ensembl
GRCm381169,916,712 - 69,921,958 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1169,916,714 - 69,921,958 (-)EnsemblGRCm38mm10GRCm38
MGSCv371169,730,214 - 69,735,460 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361169,732,917 - 69,737,536 (-)NCBIMGSCv36mm8
Celera1177,464,600 - 77,469,965 (-)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.92NCBI
Eif5a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81055,138,821 - 55,143,272 (-)NCBIGRCr8
mRatBN7.21054,640,104 - 54,644,845 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1054,640,024 - 54,644,656 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1059,302,660 - 59,307,064 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01058,791,232 - 58,795,636 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01054,298,539 - 54,302,941 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01056,527,075 - 56,531,615 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1056,527,085 - 56,531,483 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01056,272,194 - 56,276,934 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41056,760,289 - 56,764,689 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11056,773,911 - 56,778,625 (-)NCBI
Celera1053,794,046 - 53,798,461 (-)NCBICelera
Cytogenetic Map10q24NCBI
Eif5a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554679,603,800 - 9,608,490 (-)NCBIChiLan1.0ChiLan1.0
EIF5A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21914,903,844 - 14,909,346 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11716,869,683 - 16,875,178 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0177,341,076 - 7,346,570 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1177,327,363 - 7,333,270 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl177,327,363 - 7,333,270 (+)Ensemblpanpan1.1panPan2
EIF5A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1532,268,103 - 32,272,970 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha532,405,817 - 32,410,703 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0532,373,168 - 32,378,059 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl532,372,977 - 32,378,002 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1532,338,605 - 32,343,491 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0532,297,394 - 32,302,267 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0532,474,419 - 32,479,302 (+)NCBIUU_Cfam_GSD_1.0
EIF5A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11252,659,040 - 52,664,686 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23139,934,584 - 139,940,476 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EIF5A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1166,685,908 - 6,691,159 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605914,719,550 - 14,724,974 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eif5a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247869,933,325 - 9,938,178 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: XM_005332777   ⟹   XP_005332834
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560247,130,095 - 47,134,887 (+)NCBI
SpeTri2.0NW_004936595604,268 - 609,075 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005332778   ⟹   XP_005332835
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560247,130,513 - 47,134,887 (+)NCBI
SpeTri2.0NW_004936595604,707 - 609,075 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040269346   ⟹   XP_040125280
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560247,130,415 - 47,134,887 (+)NCBI
RefSeq Acc Id: XM_040269347   ⟹   XP_040125281
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560247,131,108 - 47,134,887 (+)NCBI
RefSeq Acc Id: XM_040269348   ⟹   XP_040125282
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560247,131,503 - 47,134,887 (+)NCBI
RefSeq Acc Id: XM_040269349   ⟹   XP_040125283
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560247,129,875 - 47,134,887 (+)NCBI
RefSeq Acc Id: XP_005332834   ⟸   XM_005332777
- UniProtKB: I3N6Z6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005332835   ⟸   XM_005332778
- UniProtKB: I3N6Z6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040125283   ⟸   XM_040269349
- UniProtKB: I3N6Z6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040125280   ⟸   XM_040269346
- UniProtKB: I3N6Z6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040125281   ⟸   XM_040269347
- UniProtKB: I3N6Z6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040125282   ⟸   XM_040269348
- UniProtKB: I3N6Z6 (UniProtKB/TrEMBL)

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000020652 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000024448.2 UniProtKB/TrEMBL
Gene3D-CATH 2.30.30.30 UniProtKB/TrEMBL
  2.40.50.140 UniProtKB/TrEMBL
InterPro IF5A-like UniProtKB/TrEMBL
  IF5A-like_N UniProtKB/TrEMBL
  NA-bd_OB-fold UniProtKB/TrEMBL
  Rib_L2_dom2 UniProtKB/TrEMBL
  Trans_elong_IF5A_hypusine_site UniProtKB/TrEMBL
  Transl_elong_IF5A_C UniProtKB/TrEMBL
  Translation_prot_SH3-like_sf UniProtKB/TrEMBL
NCBI Gene Eif5a ENTREZGENE
PANTHER EUKARYOTIC TRANSLATION INITIATION FACTOR 5A-1 UniProtKB/TrEMBL
  PTHR11673 UniProtKB/TrEMBL
Pfam eIF-5a UniProtKB/TrEMBL
  IF5A-like_N UniProtKB/TrEMBL
PIRSF eIF5A UniProtKB/TrEMBL
PROSITE IF5A_HYPUSINE UniProtKB/TrEMBL
SMART eIF-5a UniProtKB/TrEMBL
Superfamily-SCOP SSF50104 UniProtKB/TrEMBL
  SSF50249 UniProtKB/TrEMBL
UniProt I3N6Z6 ENTREZGENE, UniProtKB/TrEMBL