Hrh1 (histamine receptor H1) - Rat Genome Database

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Gene: Hrh1 (histamine receptor H1) Ictidomys tridecemlineatus
Analyze
Symbol: Hrh1
Name: histamine receptor H1
RGD ID: 12638488
Description: ENCODES a protein that exhibits histamine binding (ortholog); INVOLVED IN chemical synaptic transmission (ortholog); memory (ortholog); negative regulation of steroid biosynthetic process (ortholog); ASSOCIATED WITH allergic rhinitis (ortholog); atherosclerosis (ortholog); Extravasation of Diagnostic and Therapeutic Materials (ortholog); FOUND IN cytosol (inferred); dendrite (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: histamine H1 receptor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494216,634,611 - 16,727,741 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366022,183,831 - 2,185,297 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366022,182,053 - 2,185,297 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IEA)
dendrite  (IEA)
membrane  (IEA)
plasma membrane  (IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Hrh1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494216,634,611 - 16,727,741 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366022,183,831 - 2,185,297 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366022,182,053 - 2,185,297 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HRH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38311,137,238 - 11,263,557 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl311,137,093 - 11,263,557 (+)EnsemblGRCh38hg38GRCh38
GRCh37311,178,924 - 11,305,243 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36311,153,779 - 11,279,939 (+)NCBINCBI36Build 36hg18NCBI36
Build 34311,269,399 - 11,279,415NCBI
Celera311,114,216 - 11,240,363 (+)NCBICelera
Cytogenetic Map3p25.3NCBI
HuRef311,113,586 - 11,239,205 (+)NCBIHuRef
CHM1_1311,128,810 - 11,254,995 (+)NCBICHM1_1
T2T-CHM13v2.0311,131,678 - 11,258,484 (+)NCBIT2T-CHM13v2.0
Hrh1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396114,374,897 - 114,459,432 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6114,374,897 - 114,460,257 (+)EnsemblGRCm39 Ensembl
GRCm386114,397,936 - 114,483,298 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6114,397,936 - 114,483,296 (+)EnsemblGRCm38mm10GRCm38
MGSCv376114,347,930 - 114,433,290 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366114,363,531 - 114,448,891 (+)NCBIMGSCv36mm8
Celera6116,219,517 - 116,304,883 (+)NCBICelera
Cytogenetic Map6E3NCBI
cM Map653.05NCBI
Hrh1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84149,120,511 - 149,204,267 (+)NCBIGRCr8
mRatBN7.24147,564,963 - 147,649,353 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4147,645,995 - 147,647,455 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4152,949,786 - 153,033,522 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04148,730,672 - 148,814,402 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04147,360,109 - 147,443,854 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04146,374,596 - 146,458,148 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4146,455,332 - 146,457,074 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04209,668,412 - 209,751,766 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44150,431,239 - 150,432,699 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14150,676,079 - 150,677,540 (+)NCBI
Celera4136,197,254 - 136,198,714 (+)NCBICelera
RH 3.4 Map4950.0RGD
Cytogenetic Map4q42NCBI
Hrh1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542914,067,405 - 14,068,853 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542914,022,332 - 14,069,931 (+)NCBIChiLan1.0ChiLan1.0
HRH1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2211,134,626 - 11,259,909 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1311,139,386 - 11,264,669 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0311,074,451 - 11,199,871 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1311,439,705 - 11,545,509 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl311,541,294 - 11,542,757 (+)Ensemblpanpan1.1panPan2
HRH1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1207,160,903 - 7,236,147 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl207,162,393 - 7,235,869 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha207,195,842 - 7,270,946 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0207,190,337 - 7,265,418 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl207,190,251 - 7,265,315 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1206,906,408 - 6,981,475 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0207,262,781 - 7,337,859 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0207,234,680 - 7,309,540 (-)NCBIUU_Cfam_GSD_1.0
HRH1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1367,209,127 - 67,411,170 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11367,209,261 - 67,411,174 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21374,579,748 - 74,631,302 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HRH1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12247,187,156 - 47,298,761 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2247,295,011 - 47,296,471 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041119,219,292 - 119,336,578 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hrh1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624943484,942 - 486,390 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624943483,230 - 505,678 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000015283   ⟹   ENSSTOP00000013693
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366022,183,831 - 2,185,297 (-)Ensembl
RefSeq Acc Id: XM_005333796   ⟹   XP_005333853
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494216,634,611 - 16,727,741 (+)NCBI
SpeTri2.0NW_0049366022,182,053 - 2,185,297 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040290916   ⟹   XP_040146850
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494216,634,716 - 16,727,741 (+)NCBI
RefSeq Acc Id: XM_040290917   ⟹   XP_040146851
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494216,645,443 - 16,727,741 (+)NCBI
Protein Sequences
Protein RefSeqs XP_005333853 (Get FASTA)   NCBI Sequence Viewer  
  XP_040146850 (Get FASTA)   NCBI Sequence Viewer  
  XP_040146851 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000013693.1
GenBank Protein KAG3295110 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005333853   ⟸   XM_005333796
- UniProtKB: I3MPH4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040146850   ⟸   XM_040290916
- UniProtKB: I3MPH4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040146851   ⟸   XM_040290917
- UniProtKB: I3MPH4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000013693   ⟸   ENSSTOT00000015283
Protein Domains
G-protein coupled receptors family 1 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000015286 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000015283.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Histamine_H1_rcpt UniProtKB/TrEMBL
NCBI Gene Hrh1 ENTREZGENE
PANTHER 5-HYDROXYTRYPTAMINE RECEPTOR UniProtKB/TrEMBL
  HISTAMINE H1 RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  HISTAMINEH1R UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
SMART 7TM_GPCR_Srsx UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt I3MPH4 ENTREZGENE, UniProtKB/TrEMBL