Slc27a3 (solute carrier family 27 member 3)

Gene: Slc27a3 (solute carrier family 27 member 3) Ictidomys tridecemlineatus

Analyze

Symbol:

Slc27a3

Name:

solute carrier family 27 member 3

RGD ID:

12636676

Description:

ENCODES a protein that exhibits fatty-acyl-CoA synthase activity (ortholog); INVOLVED IN fatty acid transport (ortholog); ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); immunodeficiency 42 (ortholog); FOUND IN endoplasmic reticulum (inferred); mitochondrion (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

long-chain fatty acid transport protein 3

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	24,524,430 - 24,528,819 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936580	3,554,952 - 3,559,047 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936580	3,554,826 - 3,559,201 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

gastrointestinal stromal tumor (ISO)

genetic disease (ISO)

immunodeficiency 42 (ISO)

MHC class II deficiency (ISO)

parathyroid carcinoma (ISO)

severe congenital neutropenia 3 (ISO)

severe congenital neutropenia 5 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

fatty acid transport (IEA,ISO)

lipid metabolic process (IEA)

long-chain fatty acid metabolic process (IEA)

long-chain fatty acid transport (IEA)

Cellular Component

endoplasmic reticulum (IEA)

mitochondrion (IEA)

Molecular Function

fatty-acyl-CoA synthase activity (ISO)

ligase activity (IEA)

long-chain fatty acid transmembrane transporter activity (IEA)

long-chain fatty acid-CoA ligase activity (IEA)

very long-chain fatty acid-CoA ligase activity (IEA)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

Slc27a3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	24,524,430 - 24,528,819 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936580	3,554,952 - 3,559,047 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936580	3,554,826 - 3,559,201 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC27A3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	153,775,407 - 153,780,157 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	153,774,354 - 153,780,157 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	153,747,883 - 153,752,633 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	152,014,392 - 152,019,257 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	150,560,840 - 150,565,705	NCBI
Celera	1	126,819,362 - 126,824,227 (+)	NCBI		Celera
Cytogenetic Map	1	q21.3	NCBI
HuRef	1	125,110,403 - 125,115,268 (+)	NCBI		HuRef
CHM1_1	1	155,143,732 - 155,148,599 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	152,912,661 - 152,917,411 (+)	NCBI		T2T-CHM13v2.0

Slc27a3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	90,292,540 - 90,298,693 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	90,292,546 - 90,297,245 (-)	Ensembl		GRCm39 Ensembl
GRCm38	3	90,385,230 - 90,390,835 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	90,385,239 - 90,389,938 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	90,189,155 - 90,193,849 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	90,471,167 - 90,475,854 (-)	NCBI		MGSCv36	mm8
Celera	3	90,422,603 - 90,427,297 (-)	NCBI		Celera
Cytogenetic Map	3	F1	NCBI
cM Map	3	39.22	NCBI

Slc27a3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	178,150,835 - 178,155,503 (-)	NCBI		GRCr8
mRatBN7.2	2	175,853,241 - 175,857,909 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	175,853,241 - 175,857,909 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	182,993,207 - 182,997,902 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	181,015,449 - 181,020,144 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	175,615,663 - 175,620,341 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	189,760,747 - 189,765,415 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	189,760,747 - 189,765,415 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	209,191,620 - 209,196,288 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	182,643,984 - 182,648,652 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	182,594,203 - 182,598,937 (-)	NCBI
Celera	2	169,788,114 - 169,792,782 (-)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

Slc27a3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955545	396,102 - 400,188 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955545	395,938 - 400,324 (+)	NCBI	ChiLan1.0	ChiLan1.0

SLC27A3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	96,052,339 - 96,057,698 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	95,787,573 - 95,792,474 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	129,131,843 - 129,136,746 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	132,759,389 - 132,765,194 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	132,759,952 - 132,765,194 (+)	Ensembl	panpan1.1		panPan2

SLC27A3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	43,321,059 - 43,325,766 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	43,321,130 - 43,325,089 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	42,811,229 - 42,815,259 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	43,191,250 - 43,195,280 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	43,191,321 - 43,195,280 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	42,969,550 - 42,973,580 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	43,022,845 - 43,026,875 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	43,306,640 - 43,310,670 (-)	NCBI		UU_Cfam_GSD_1.0

SLC27A3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	95,898,804 - 95,903,604 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	95,898,780 - 95,903,599 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	104,797,201 - 104,801,637 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC27A3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	10,031,007 - 10,037,082 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	10,031,164 - 10,035,876 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	9,404,894 - 9,410,226 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc27a3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624885	3,395,839 - 3,402,542 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624885	3,398,652 - 3,403,376 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005331269	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000117	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000024901 ⟹ ENSSTOP00000020281

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936580	3,554,952 - 3,559,047 (+)	Ensembl

RefSeq Acc Id:

XM_005331269 ⟹ XP_005331326

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	24,524,430 - 24,528,819 (+)	NCBI
SpeTri2.0	NW_004936580	3,554,826 - 3,559,201 (+)	NCBI

Sequence:

show sequence

CGCGCGCGCTCCCGAAAAGGAGAGGTCCCAGAGCAAGAAGGAGCGGGCCCAGTTTTTCGGAGGG
AGTATCAGGGGTGTTTGTGAGCGTCTAGGGCCGGTCGCTGCCGAGGAAAGGAAGAGGGCACCAT
GGCTGCCCTGCTACTGCTTCCCCTGCTCCTGCTGCTGCCTCTGCTGCTACTGAAGCTGCACCTC
TGGCCGCAGTTGCGCTGGCTCGCGGCCGACTTGGCCTTCACGGTGCGCGCCCTCCGCTGCAAAA
GGGCTCTGCGAGCTCGTATGCTGGCTGCGGCTGCCGCCGACCCAGAAGGTCCGGAGGGGGGCTG
CAGCCTGGCCTGGCGCCTCGCGCAACTGGCTCGGCAACGCCCGGCACACACCTTCCTCATTCAC
GGCGCGCGGCGCTTTAGTTACGCGCAGGCGGAACGTGAGAGTAACCGGGCTGCGCGCGCCTTCT
TGCGCGCGCAGGGCTGGGACCCGGGACGCGGCGGAGGCGTCAGGGCGGCGGGGAGCCCGTGGGC
AGGAGACCCAGCAGCCGGAAGCAGCGCGGCGCCTCCAAAGGATGGGGTGGCCGGAGATGAAGGA
GCCATGGCCCCTCTGGCACCTGGGGCGACCGTGGCGCTTCTCCTCCCCGCCAGCCCAGAATTCC
TGTGGCTCTGGTTCGGGCTGGCCAAGGCCGGCTTGTGCACGGCCTTCGTGCCCACCGCCCTGCG
TCGGGGCCCCCTGCTGCATTGCCTTCGCAGCTGCAGTGCGCGCGCGCTGGTGTTGGCGCCAGAA
TTCCTGGACTCCCTGGAGCCCGACCTGCCGGCCCTGAGAGCCATGGGGCTCCGCCTGTGGACCA
CGGGTCCCGAGACCCATCTTACTGGAGTCAGCGACTTCCTGGCTGAGGCAGCAGCCGAAATAGA
TGAGCCTCTGCCGGGATACCTCTCTGCCCCCCAGAACATGATGGACACGTGCCTGTACATCTTC
ACCTCTGGCACCACGGGCCTCCCCAAGGCTGCTCGGATCAGTCACCTGAAGATCCTCCAGTGCC
AGGGATTCTACCAGTTGTGCGGTGTCCACCCGGAGGACGTCATCTACCTCGCCCTGCCACTCTA
CCACATGTCGGGCTCCCTGCTGGGCATCGTGGGCTGCCTGGGCATCGGGGCCACAGTGGTGCTG
AAGTCCAAGTTCTCAGCTGGCCAGTTCTGGGAGGACTGCCAGGAGCACAGGGTGACGGTGTTCC
AGTACATCGGGGAGCTGTGCCGATACCTGGTCAACCAGCCCCCGAGCAAAGCAGAACTTGGCCA
CAAGGTCCGGCTGGCAGTGGGCAGCGGGCTGCGCCCTGACACCTGGGAGCGTTTTGTGCGGCGC
TTTGGGCCTCTGCAGGTGCTGGAGACGTACGGACTGACGGAGGGCAACGTGGCCACTTTCAACT
ACACGGGGCAGCGCGGTGCTGTGGGACGTGCCTCCTGGCTCTACAAGCACATCTTCCCCTTCTC
TTTGATTCGCTATGACGTCGCCACAGGGGAGCCAGTTCGGGATGCCCAGGGGCACTGTGTAGCC
ACATCTCCAGGTGAGCCAGGGCTGCTGGTGGCCCCCGTGAGCCAGCAGTCCCCATTCTTGGGCT
ACGCCGGGGGCCCAGAGCTGGCCTGGGGAAAGCTGCTGGTGGACGTCTTCCGGCCTGGAGACGT
TTTCTTCAACACGGGGGACCTGCTGGTGTGCGATGACCAAGGCTTCCTCCGCTTCCACGACCGC
ACTGGAGACACCTTCAGGTGGAAAGGGGAGAATGTGGCCACAACTGAGGTGGCGGAGGTCTTTG
AGGCCCTGGACTTCCTTCAGGAGGTGAACGTCTACGGAGTCACGGTGCCAGGGCACGAAGGCAG
GGCTGGGATGGCAGCCCTGGCTCTGCGTCCCCCCCACGCTTTAGACCTTGTGCAGCTCCACGCC
CACGTTTCTGACAACCTGCCCCCTTACGCCCGGCCTCGGTTCCTCAGGCTTCAGGAATCCTTGG
CCACCACCGAGACCTTCAAACAGCAGAAGGTTCGGATGGCCAACGAGGGCTTCGACCCGAGCAC
CCTGTCTGACCCCCTCTACGTTCTGGACCAGGCCGTCGGTGCCTACCTGCCCCTCACACCTGCA
CGGTACAGTGCCCTTCTGGCTGGGGATCTTCGAATCTGAGACCTTCCAGGCCCGAGGCACCTTG
GGAGGGACTCTGGGGCTGCTCTGAGACACGCCCGTGTGGGCGCACCAGGGCTCTCAGGGAACTT
TTTTATATCCGTTTATTGTCATTTTATAATAAATGGGACCAAGCCCACGCGTGTCTGCCTTCTG
A

hide sequence

Protein Sequences


Protein RefSeqs	XP_005331326	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000020281.2
GenBank Protein	KAG3281627	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_005331326 ⟸ XM_005331269

- UniProtKB:

I3N7D5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAALLLLPLLLLLPLLLLKLHLWPQLRWLAADLAFTVRALRCKRALRARMLAAAAADPEGPEGG
CSLAWRLAQLARQRPAHTFLIHGARRFSYAQAERESNRAARAFLRAQGWDPGRGGGVRAAGSPW
AGDPAAGSSAAPPKDGVAGDEGAMAPLAPGATVALLLPASPEFLWLWFGLAKAGLCTAFVPTAL
RRGPLLHCLRSCSARALVLAPEFLDSLEPDLPALRAMGLRLWTTGPETHLTGVSDFLAEAAAEI
DEPLPGYLSAPQNMMDTCLYIFTSGTTGLPKAARISHLKILQCQGFYQLCGVHPEDVIYLALPL
YHMSGSLLGIVGCLGIGATVVLKSKFSAGQFWEDCQEHRVTVFQYIGELCRYLVNQPPSKAELG
HKVRLAVGSGLRPDTWERFVRRFGPLQVLETYGLTEGNVATFNYTGQRGAVGRASWLYKHIFPF
SLIRYDVATGEPVRDAQGHCVATSPGEPGLLVAPVSQQSPFLGYAGGPELAWGKLLVDVFRPGD
VFFNTGDLLVCDDQGFLRFHDRTGDTFRWKGENVATTEVAEVFEALDFLQEVNVYGVTVPGHEG
RAGMAALALRPPHALDLVQLHAHVSDNLPPYARPRFLRLQESLATTETFKQQKVRMANEGFDPS
TLSDPLYVLDQAVGAYLPLTPARYSALLAGDLRI

hide sequence

RefSeq Acc Id:

ENSSTOP00000020281 ⟸ ENSSTOT00000024901

Protein Domains

AMP-binding enzyme C-terminal AMP-dependent synthetase/ligase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000020359	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000024901.2	UniProtKB/TrEMBL
Gene3D-CATH	3.30.300.30	UniProtKB/TrEMBL
	3.40.50.12780	UniProtKB/TrEMBL
InterPro	AMP-bd_C	UniProtKB/TrEMBL
	AMP-bd_C_sf	UniProtKB/TrEMBL
	AMP-binding_CS	UniProtKB/TrEMBL
	AMP-dep_Synth/Lig	UniProtKB/TrEMBL
	ANL_N_sf	UniProtKB/TrEMBL
NCBI Gene	Slc27a3	ENTREZGENE
PANTHER	LONG-CHAIN FATTY ACID TRANSPORT PROTEIN	UniProtKB/TrEMBL
	PTHR43107:SF12	UniProtKB/TrEMBL
Pfam	AMP-binding	UniProtKB/TrEMBL
	AMP-binding_C	UniProtKB/TrEMBL
PROSITE	AMP_BINDING	UniProtKB/TrEMBL
Superfamily-SCOP	Acetyl-CoA synthetase-like	UniProtKB/TrEMBL
UniProt	I3N7D5	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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