Ca4 (carbonic anhydrase 4) - Rat Genome Database

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Gene: Ca4 (carbonic anhydrase 4) Ictidomys tridecemlineatus
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Symbol: Ca4
Name: carbonic anhydrase 4
RGD ID: 12635892
Description: ENCODES a protein that exhibits carbonate dehydratase activity (ortholog); INVOLVED IN animal organ development (ortholog); bicarbonate transport (ortholog); response to drug (ortholog); ASSOCIATED WITH Colonic Neoplasms (ortholog); fundus dystrophy (ortholog); retinitis pigmentosa (ortholog); FOUND IN anchored component of external side of plasma membrane (ortholog); anchored component of plasma membrane (ortholog); apical plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560235,301,294 - 35,310,173 (-)NCBI
SpeTri2.0NW_0049364901,764,845 - 1,773,752 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

Genomics

Comparative Map Data
Ca4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560235,301,294 - 35,310,173 (-)NCBI
SpeTri2.0NW_0049364901,764,845 - 1,773,752 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CA4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1760,149,942 - 60,170,899 (+)EnsemblGRCh38hg38GRCh38
GRCh381760,149,942 - 60,179,021 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371758,227,334 - 58,256,382 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361755,582,131 - 55,591,686 (+)NCBINCBI36hg18NCBI36
Build 341755,582,130 - 55,591,686NCBI
Celera1754,687,198 - 54,696,791 (+)NCBI
Cytogenetic Map17q23.1NCBI
HuRef1753,598,240 - 53,607,844 (+)NCBIHuRef
CHM1_11758,291,334 - 58,300,936 (+)NCBICHM1_1
Car4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391184,848,580 - 84,856,880 (+)NCBIGRCm39mm39
GRCm39 Ensembl1184,848,612 - 84,856,870 (+)Ensembl
GRCm381184,957,754 - 84,966,054 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1184,957,786 - 84,966,044 (+)EnsemblGRCm38mm10GRCm38
MGSCv371184,771,256 - 84,779,556 (+)NCBIGRCm37mm9NCBIm37
MGSCv361184,774,038 - 84,782,239 (+)NCBImm8
Celera1194,577,982 - 94,586,281 (+)NCBICelera
Cytogenetic Map11CNCBI
Ca4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21069,827,945 - 69,836,501 (+)NCBI
Rnor_6.0 Ensembl1072,272,248 - 72,281,067 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01072,272,286 - 72,281,069 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01072,173,022 - 72,188,138 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41073,229,211 - 73,237,707 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11073,243,580 - 73,252,077 (+)NCBI
Celera1068,755,736 - 68,764,294 (+)NCBICelera
Cytogenetic Map10q26NCBI
Ca4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554511,486,010 - 1,494,084 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554511,485,939 - 1,493,249 (+)NCBIChiLan1.0ChiLan1.0
CA4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Mhudiblu_PPA_v01754,236,114 - 54,258,638 (+)NCBIMhudiblu_PPA_v0panPan3
CA4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1936,327,919 - 36,337,103 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl936,327,969 - 36,337,088 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha935,555,114 - 35,563,663 (-)NCBI
ROS_Cfam_1.0937,140,849 - 37,149,372 (-)NCBI
UMICH_Zoey_3.1935,919,574 - 35,928,095 (-)NCBI
UNSW_CanFamBas_1.0936,206,744 - 36,215,265 (-)NCBI
UU_Cfam_GSD_1.0936,294,940 - 36,303,505 (-)NCBI
CA4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1237,962,943 - 37,972,509 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11237,962,951 - 37,972,443 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21239,632,792 - 39,642,290 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CA4
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11631,369,238 - 31,379,366 (+)NCBI
Ca4
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248713,462,577 - 3,469,978 (-)NCBI


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005321536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_005321536   ⟹   XP_005321593
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440560235,301,294 - 35,310,173 (-)NCBI
SpeTri2.0NW_0049364901,764,845 - 1,773,752 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005321593 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005321593   ⟸   XM_005321536
- UniProtKB: I3MFH1 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
Alpha-carbonic anhydrase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000010432 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000009363 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000010433 UniProtKB/TrEMBL
Gene3D-CATH 3.10.200.10 UniProtKB/TrEMBL
InterPro CA4/CA15 UniProtKB/TrEMBL
  Carbonic_anhydrase_a UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class_CS UniProtKB/TrEMBL
  Carbonic_anhydrase_a_sf UniProtKB/TrEMBL
  Carbonic_anhydrase_CA4 UniProtKB/TrEMBL
NCBI Gene Ca4 ENTREZGENE
PANTHER PTHR18952 UniProtKB/TrEMBL
  PTHR18952:SF95 UniProtKB/TrEMBL
Pfam Carb_anhydrase UniProtKB/TrEMBL
PROSITE ALPHA_CA_1 UniProtKB/TrEMBL
  ALPHA_CA_2 UniProtKB/TrEMBL
SMART Carb_anhydrase UniProtKB/TrEMBL
Superfamily-SCOP SSF51069 UniProtKB/TrEMBL
UniProt I3MFH1 ENTREZGENE, UniProtKB/TrEMBL